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AU2001295891A1 - Method for the preparation of a non-woven silk fibroin fabrics - Google Patents

Method for the preparation of a non-woven silk fibroin fabrics

Info

Publication number
AU2001295891A1
AU2001295891A1 AU2001295891A AU9589101A AU2001295891A1 AU 2001295891 A1 AU2001295891 A1 AU 2001295891A1 AU 2001295891 A AU2001295891 A AU 2001295891A AU 9589101 A AU9589101 A AU 9589101A AU 2001295891 A1 AU2001295891 A1 AU 2001295891A1
Authority
AU
Australia
Prior art keywords
silk
silk fibroin
preparation
kda
woven silk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001295891A
Inventor
Ubaldo Armato
Ilaria Dal Pra
Kemal Kesenci
Claudio Migliaresi
Antonella Motta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consorzio per gli Studi Universitari di Verona
Original Assignee
CONSORZIO PER GLI STUDI UNI
Consorzio per gli Studi Universitari di Verona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CONSORZIO PER GLI STUDI UNI, Consorzio per gli Studi Universitari di Verona filed Critical CONSORZIO PER GLI STUDI UNI
Publication of AU2001295891A1 publication Critical patent/AU2001295891A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/225—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/40—Formation of filaments, threads, or the like by applying a shearing force to a dispersion or solution of filament formable polymers, e.g. by stirring
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00—Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • D01F4/02—Monocomponent artificial filaments or the like of proteins; Manufacture thereof from fibroin
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
    • D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
    • D04H1/4266—Natural fibres not provided for in group D04H1/425
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H3/00—Non-woven fabrics formed wholly or mainly of yarns or like filamentary material of substantial length
    • D04H3/015—Natural yarns or filaments

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Textile Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Woven Fabrics (AREA)
  • Artificial Filaments (AREA)

Abstract

A process for producing non-woven silk fiber fabrics comprises the following steps: a) obtaining silk fibroin, for example either from silk cocoons, or silk textiles or waste silk; b) removing the sercin layer covering the silk fibroin fibers, when present; c) breaking the disulfide bonds between heavy (350 kDa) and light (27 kDa) chains of silk fibroin in order to obtain the production of chain fragments which serve as a specific cellular recognition sites promoting the attachment and growth of cells, d) homogenising of the material resulting from step c).
AU2001295891A 2000-10-02 2001-09-28 Method for the preparation of a non-woven silk fibroin fabrics Abandoned AU2001295891A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITVR200A000096 2000-10-02
IT2000VR000096A IT1316885B1 (en) 2000-10-02 2000-10-02 PROCEDURE FOR THE PREPARATION OF A NON-WOVEN FABRIC IN SILK FIBER.
PCT/IT2001/000501 WO2002029141A1 (en) 2000-10-02 2001-09-28 Method for the preparation of a non-woven silk fibroin fabrics

Publications (1)

Publication Number Publication Date
AU2001295891A1 true AU2001295891A1 (en) 2002-04-15

Family

ID=11461889

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001295891A Abandoned AU2001295891A1 (en) 2000-10-02 2001-09-28 Method for the preparation of a non-woven silk fibroin fabrics

Country Status (8)

Country Link
US (1) US7285637B2 (en)
EP (1) EP1327014B1 (en)
AT (1) ATE310840T1 (en)
AU (1) AU2001295891A1 (en)
DE (1) DE60115271T2 (en)
ES (1) ES2254500T3 (en)
IT (1) IT1316885B1 (en)
WO (1) WO2002029141A1 (en)

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AU2002367580A1 (en) * 2001-05-16 2003-09-22 Tracy C. Grikscheit Tissue-engineered organs
EP1446169B1 (en) 2001-10-25 2009-01-14 University of Connecticut Fibroin compositions and methods of making the same
US20110009960A1 (en) * 2001-11-16 2011-01-13 Allergan, Inc. Prosthetic fabric structure
US6902932B2 (en) * 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
JP2005515309A (en) * 2002-01-09 2005-05-26 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー Polypeptide fibers and methods for their production
EP1558444B1 (en) * 2002-06-24 2016-09-21 Tufts University Silk biomaterials and methods of use thereof
US7842780B2 (en) * 2003-01-07 2010-11-30 Trustees Of Tufts College Silk fibroin materials and use thereof
JP4815554B2 (en) * 2003-03-11 2011-11-16 アラーガン、インコーポレイテッド Medical device based on immune neutral silk fiber
JP4698596B2 (en) * 2003-04-10 2011-06-08 タフツ ユニバーシティー Concentrated aqueous silk fibroin solutions and their use
WO2005000483A1 (en) * 2003-06-06 2005-01-06 Tufts University Method for forming inorganic coatings
US8178656B2 (en) 2004-06-11 2012-05-15 Trustees Of Tufts College Silk-based drug delivery system
KR100762928B1 (en) 2004-10-29 2007-10-04 재단법인서울대학교산학협력재단 Non-woven form of bone tissue-induced regeneration shielding membrane made of silk fibroin nanofibers and method for manufacturing same
US9102916B2 (en) 2007-02-27 2015-08-11 Trustees Of Tufts College Tissue-engineered silk organs
US8172901B2 (en) 2007-03-20 2012-05-08 Allergan, Inc. Prosthetic device and method of manufacturing the same
PL2211876T3 (en) 2007-05-29 2015-05-29 Tufts College Method for silk fibroin gelation using sonication
EP2249886A4 (en) * 2008-02-07 2013-05-22 Tufts College THREE DIMENSIONAL HYDROXYAPATITIS AND SILK COMPOSITIONS
GB0807868D0 (en) * 2008-04-30 2008-06-04 Knight David P Cartilage repair material and a method for the preparation thereof
MX341351B (en) * 2008-05-15 2016-08-17 Tufts College Silk polymer-based adenosine release: therapeutic potential for epilepsy.
US8501172B2 (en) * 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
MX2011003618A (en) 2008-10-09 2011-06-16 Tufts College Modified silk films containing glycerol.
US9204953B2 (en) 2008-12-15 2015-12-08 Allergan, Inc. Biocompatible surgical scaffold with varying stretch
BRPI0922440A2 (en) 2008-12-15 2018-10-23 Allergan Inc prosthetic device and method of manufacture thereof.
US9326840B2 (en) 2008-12-15 2016-05-03 Allergan, Inc. Prosthetic device and method of manufacturing the same
US9308070B2 (en) * 2008-12-15 2016-04-12 Allergan, Inc. Pliable silk medical device
US9204954B2 (en) * 2008-12-15 2015-12-08 Allergan, Inc. Knitted scaffold with diagonal yarn
CA2812635A1 (en) 2009-07-14 2011-01-20 Trustees Of Tufts College Electrospun silk material systems for wound healing
WO2011031854A1 (en) * 2009-09-11 2011-03-17 Allergan, Inc. Prosthetic device and method of manufacturing the same
WO2011038401A2 (en) * 2009-09-28 2011-03-31 Trustees Of Tufts College Drawn silk egel fibers and methods of making same
IN2012DN02358A (en) 2009-09-29 2015-08-21 Tufts College
WO2011109691A2 (en) 2010-03-05 2011-09-09 Trustees Of Tufts College Silk-based ionomeric compositions
US8309689B2 (en) 2010-05-20 2012-11-13 Taipei Medical University High yield dialysis-free process for producing organosoluble regenerated silk fibroin
US9566365B2 (en) 2010-09-01 2017-02-14 Trustees Of Tufts College Silk fibroin and polyethylene glycol-based biomaterials
US10933173B2 (en) 2010-10-19 2021-03-02 Trustees Of Tufts College Silk fibroin-based microneedles and methods of making the same
US10335519B2 (en) 2011-04-20 2019-07-02 Trustees Of Tufts College Dynamic silk coatings for implantable devices
EP2811987B1 (en) 2012-02-06 2021-01-20 Children's Medical Center Corporation Multi-layer biomaterial for tissue regeneration and wound healing
WO2013152265A1 (en) * 2012-04-06 2013-10-10 Trustees Of Tufts College Methods of producing and using silk microfibers
KR101313898B1 (en) 2012-04-27 2013-09-30 서울대학교산학협력단 Silk fibroin nanofiber comprising hydroxyapatite nanoparticles modified with hyaluronic acid/dopamine conjugate, and scaffold using the same
EP2712955A1 (en) 2012-09-27 2014-04-02 Ludwig Boltzmann Gesellschaft GmbH Product made of silk
CN103446623B (en) * 2013-09-18 2015-03-11 中国人民解放军军事医学科学院卫生装备研究所 Construction method of tissue engineering epidermis model
CN103668782B (en) * 2013-11-29 2016-05-11 温州医科大学 The electrostatic spinning preparation method of the bionical Bruch ' s of ultra-thin porous composite nano fiber film
KR101573838B1 (en) * 2014-06-13 2015-12-07 대한민국 Artificial biomembrane using Cocoon and Method for manufacturing thereof
KR101714545B1 (en) * 2014-06-26 2017-03-15 대한민국 The manufacture method of osteogenic enhancing membrane and osteogenic enhancing membrane using the same
KR101570717B1 (en) 2014-08-04 2015-11-24 대한민국 Dental Membrain using Cocoon and Method for manufacturing thereof
US9394355B2 (en) 2014-08-20 2016-07-19 Silk Technologies, Ltd. Fibroin-derived protein composition
WO2016172689A1 (en) 2015-04-23 2016-10-27 Rowan University Processes of increasing crystallinity alignment of protein films and products thereof
AU2017243878B2 (en) * 2016-03-31 2021-09-09 Deakin University Improved silk fibroin glycerol membranes
US11298443B2 (en) 2016-07-01 2022-04-12 Trustees Of Tufts College Innervated artificial skin
AU2017310520A1 (en) 2016-08-12 2019-03-21 Silk Technologies, Ltd. Silk-derived protein for treating inflammation
WO2018195048A1 (en) * 2017-04-17 2018-10-25 Rowan University Solution blow spun protein-based polymer fibers and products comprising same
US20200188178A1 (en) * 2018-12-18 2020-06-18 National Taiwan University Of Science And Technology Double-layer dressing containing silk fibroin and a method for making the same
US20220247559A1 (en) * 2021-02-03 2022-08-04 Gwangju Institute Of Science And Technology Puf id and puf id reader
CN116392636A (en) * 2023-03-29 2023-07-07 深圳高性能医疗器械国家研究院有限公司 Silk repairing patch and preparation method thereof
CN116712612B (en) * 2023-07-13 2025-08-26 上海市肺科医院（上海市职业病防治院） A tissue engineering bionic tracheal stent with microenvironment regulation function and its preparation method

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US976977A (en) 1908-11-27 1910-11-29 Carl Rudolf Baumann Process for obtaining silk fibroin.
US5171505A (en) 1990-11-28 1992-12-15 E. I. Du Pont De Nemours And Company Process for spinning polypeptide fibers
DE19841649A1 (en) 1998-09-11 2000-04-27 Thueringisches Inst Textil Production of solutions of fibrillar proteins, especially silk, comprises dissolving the protein in N-methylmorpholine N-oxide

Also Published As

Publication number Publication date
ITVR20000096A0 (en) 2000-10-02
EP1327014A1 (en) 2003-07-16
DE60115271D1 (en) 2005-12-29
US20040097709A1 (en) 2004-05-20
ATE310840T1 (en) 2005-12-15
DE60115271T2 (en) 2006-08-24
ES2254500T3 (en) 2006-06-16
EP1327014B1 (en) 2005-11-23
ITVR20000096A1 (en) 2002-04-02
US7285637B2 (en) 2007-10-23
IT1316885B1 (en) 2003-05-13
WO2002029141A1 (en) 2002-04-11

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