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AU2001295073A1 - Dendrimeric support or carrier macromolecule - Google Patents

Dendrimeric support or carrier macromolecule

Info

Publication number
AU2001295073A1
AU2001295073A1 AU2001295073A AU9507301A AU2001295073A1 AU 2001295073 A1 AU2001295073 A1 AU 2001295073A1 AU 2001295073 A AU2001295073 A AU 2001295073A AU 9507301 A AU9507301 A AU 9507301A AU 2001295073 A1 AU2001295073 A1 AU 2001295073A1
Authority
AU
Australia
Prior art keywords
dendrimeric
support
carrier macromolecule
macromolecule
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001295073A
Inventor
Jean J. Frechet
Rolf H. Ihre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California
University of California Berkeley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California, University of California Berkeley filed Critical University of California
Publication of AU2001295073A1 publication Critical patent/AU2001295073A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002Dendritic macromolecules
    • C08G83/003Dendrimers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593Polyesters, e.g. PLGA or polylactide-co-glycolide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU2001295073A 2000-09-29 2001-09-25 Dendrimeric support or carrier macromolecule Abandoned AU2001295073A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23656100P 2000-09-29 2000-09-29
US60/236,561 2000-09-29
PCT/US2001/042310 WO2002026867A2 (en) 2000-09-29 2001-09-25 Dendrimeric support or carrier macromolecule

Publications (1)

Publication Number Publication Date
AU2001295073A1 true AU2001295073A1 (en) 2002-04-08

Family

ID=22890010

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001295073A Abandoned AU2001295073A1 (en) 2000-09-29 2001-09-25 Dendrimeric support or carrier macromolecule

Country Status (3)

Country Link
US (1) US7097856B2 (en)
AU (1) AU2001295073A1 (en)
WO (1) WO2002026867A2 (en)

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US8652484B2 (en) * 2004-02-13 2014-02-18 Immunomedics, Inc. Delivery system for cytotoxic drugs by bispecific antibody pretargeting
CA2560667A1 (en) * 2004-03-23 2005-11-03 Lytone Enterprise, Inc. Chitosan embedded or encapsulated capsule
JP2008510829A (en) * 2004-08-25 2008-04-10 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン Compositions based on dendrimers and their use
CN101035823B (en) 2004-10-08 2012-07-04 弗门尼舍有限公司 Amphiphilic star block copolymers
JP2008530307A (en) * 2005-02-10 2008-08-07 エモリー ユニヴァーシティ Polyethylene oxide polymer containing anti-inflammatory glycodendron
US7723438B2 (en) * 2005-04-28 2010-05-25 International Business Machines Corporation Surface-decorated polymeric amphiphile porogens for the templation of nanoporous materials
US20070048759A1 (en) * 2005-06-10 2007-03-01 Dan Luo Detection of target molecules with labeled nucleic acid detection molecules
US8486621B2 (en) * 2005-08-11 2013-07-16 Cornell Research Foundation, Inc. Nucleic acid-based matrixes
US20070148246A1 (en) * 2005-08-11 2007-06-28 Dan Luo Nucleic Acid-Based Matrixes
HUE031341T2 (en) 2005-10-25 2017-07-28 Starpharma Pty Ltd Macromolecular compounds having controlled stoichiometry
EP1969031B1 (en) * 2005-12-05 2009-06-03 Nitto Denko Corporation Polyglutamate-amino acid conjugates and methods
TWI311486B (en) * 2005-12-30 2009-07-01 Ind Tech Res Inst Nuclear molecular imaging contrast agent
US9603941B2 (en) * 2006-01-24 2017-03-28 Minghui Chai Method of preparing dendritic drugs
US8329155B2 (en) * 2006-03-10 2012-12-11 Montana State University Quaternary ammonium functionalized glycodendrimers, methods for the production and use thereof
US20080020043A1 (en) * 2006-07-20 2008-01-24 Marc Gingras Dendrimer-Drug Conjugates
US8969622B2 (en) * 2006-08-23 2015-03-03 Vanderbilt University Dendritic molecular intracellular transporters and methods of making and using same
US20080181852A1 (en) * 2007-01-29 2008-07-31 Nitto Denko Corporation Multi-functional Drug Carriers
US20080221224A1 (en) * 2007-03-06 2008-09-11 Sheiko Sergei S Unimolecular tweezers
CN101674852A (en) * 2007-04-10 2010-03-17 日东电工株式会社 Multifunctional polyglutamate drug carriers
US8197828B2 (en) * 2007-05-09 2012-06-12 Nitto Denko Corporation Compositions that include a hydrophobic compound and a polyamino acid conjugate
MX2007013267A (en) * 2007-10-24 2009-05-11 Itesm Multifunctional dendrons and dendrimers with a high loading capacity.
US11254786B2 (en) 2007-11-05 2022-02-22 Vanderbilt University Multifunctional degradable nanoparticles with control over size and functionalities
US20130142733A1 (en) 2007-11-05 2013-06-06 Vanderbilt University Multifunctional degradable nanoparticles with control over size and functionalities
EP3574925A1 (en) * 2007-11-05 2019-12-04 Vanderbilt University Multifunctional degradable nanoparticles with control over size and functionalities
WO2009067175A2 (en) 2007-11-16 2009-05-28 Nektar Therapeutics Al, Corporation Oligomer-dantrolene conjugates and related compounds
US8303937B2 (en) * 2007-12-31 2012-11-06 Industrial Technology Research Institute Dendritic polymers and magnetic resonance imaging contrast agent employing the same
RU2010137032A (en) * 2008-03-06 2012-04-20 Нитто Денко Корпорейшн (Jp) PACLITAXEL CONJUGATES WITH POLYMER AND METHODS FOR TREATING CANCER
WO2009151687A2 (en) * 2008-03-12 2009-12-17 The Regents Of The University Of Michigan Dendrimer conjugates
US8889635B2 (en) * 2008-09-30 2014-11-18 The Regents Of The University Of Michigan Dendrimer conjugates
US8535655B2 (en) 2008-10-10 2013-09-17 Polyactiva Pty Ltd. Biodegradable polymer—bioactive moiety conjugates
WO2010040187A1 (en) 2008-10-10 2010-04-15 The Bionic Ear Institute Polymer-bioactive agent conjugates
WO2010054321A2 (en) 2008-11-07 2010-05-14 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
WO2010075423A2 (en) * 2008-12-23 2010-07-01 The Regents Of The University Of Michigan Dendrimer based modular platforms
US8846848B2 (en) 2009-02-03 2014-09-30 The Administrators Of The Tulane Educational Fund Tuned synthetic dendrimer calibrants for mass spectrometry
TW201035104A (en) * 2009-03-27 2010-10-01 Chunghwa Chemical Synthesis & Biotech Co Ltd Improved synthesis method for Temsirolimus and its similar compounds
US8524784B2 (en) 2009-04-30 2013-09-03 Intezyne Technologies, Incorporated Polymer micelles containing anthracylines for the treatment of cancer
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US8912323B2 (en) 2009-10-30 2014-12-16 The Regents Of The University Of Michigan Multifunctional small molecules
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WO2013108988A1 (en) * 2012-01-17 2013-07-25 서울대학교 산학협력단 Hyperbranched polyether compound, and poly(vinyl chloride) composition containing same
US9987199B2 (en) * 2012-07-10 2018-06-05 Tokuyama Dental Corporation Dental adhesive composition, dental adhesive primer, dental adhesive bonding material, dental adhesivecomposite resin, and dental adhesive resin cement
WO2016201310A1 (en) 2015-06-12 2016-12-15 Rhodia Operations Hybrid nanoparticles containing dendrons, methods of producing such hybrid nanoparticles, and uses thereof
US10869939B2 (en) * 2015-08-03 2020-12-22 Ramot At Tel-Aviv University Ltd. Delivery system in micellar form having modular spectral response based on enzyme-responsive amphiphilic PEG-dendron hybrid polymers
KR101823490B1 (en) 2016-09-08 2018-01-30 한국과학기술연구원 Oxamide nanogel, a preparation method of the same and use thereof
CN113797353B (en) * 2020-06-12 2023-10-20 南京工业大学 Combined therapeutic agent for radiotherapy and chemotherapy and preparation method thereof
CN112057631A (en) * 2020-08-20 2020-12-11 华南理工大学 Application of a modified dendrimer in protein intracellular delivery
CN112461807B (en) * 2020-11-26 2021-11-19 山西大学 Application of carbon quantum dots in targeted nucleolus wash-free imaging
US11851454B2 (en) 2021-12-30 2023-12-26 Hongene Biotech Corporation Compositions and methods for liquid phase oligonucleotide synthesis
EP4543960A1 (en) * 2022-06-21 2025-04-30 Hongene Biotech Corporation Compositions and methods for liquid phase oligonucleotide synthesis
CN115920139B (en) * 2022-11-25 2024-07-02 杭州矩正医疗科技有限公司 Photodynamic saccule catheter system
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Also Published As

Publication number Publication date
WO2002026867A2 (en) 2002-04-04
US20020123609A1 (en) 2002-09-05
US7097856B2 (en) 2006-08-29
WO2002026867A3 (en) 2002-11-07

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