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AU2001291028A1 - Apparatus and method for preparing microparticles using liquid-liquid extraction - Google Patents

Apparatus and method for preparing microparticles using liquid-liquid extraction

Info

Publication number
AU2001291028A1
AU2001291028A1 AU2001291028A AU9102801A AU2001291028A1 AU 2001291028 A1 AU2001291028 A1 AU 2001291028A1 AU 2001291028 A AU2001291028 A AU 2001291028A AU 9102801 A AU9102801 A AU 9102801A AU 2001291028 A1 AU2001291028 A1 AU 2001291028A1
Authority
AU
Australia
Prior art keywords
liquid
preparing microparticles
extraction
liquid extraction
microparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001291028A
Inventor
J. Mickael Ramstack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alkermes Controlled Therapeutics Inc II
Original Assignee
Alkermes Inc
Alkermes Controlled Therapeutics Inc II
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkermes Inc, Alkermes Controlled Therapeutics Inc II filed Critical Alkermes Inc
Publication of AU2001291028A1 publication Critical patent/AU2001291028A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001291028A 2000-09-27 2001-09-18 Apparatus and method for preparing microparticles using liquid-liquid extraction Abandoned AU2001291028A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/671,426 US6471995B1 (en) 2000-09-27 2000-09-27 Apparatus and method for preparing microparticles using liquid-liquid extraction
US09671426 2000-09-27
PCT/US2001/028999 WO2002026371A2 (en) 2000-09-27 2001-09-18 Apparatus and method for preparing microparticles using liquid-liquid extraction

Publications (1)

Publication Number Publication Date
AU2001291028A1 true AU2001291028A1 (en) 2002-04-08

Family

ID=24694463

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001291028A Abandoned AU2001291028A1 (en) 2000-09-27 2001-09-18 Apparatus and method for preparing microparticles using liquid-liquid extraction

Country Status (3)

Country Link
US (3) US6471995B1 (en)
AU (1) AU2001291028A1 (en)
WO (1) WO2002026371A2 (en)

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DE60138641D1 (en) 2000-10-27 2009-06-18 Baxter Healthcare Sa PREPARATION OF MICRO BEADS
ES2307779T3 (en) * 2001-08-16 2008-12-01 Baxter International Inc. FORMULATIONS OF PROPELLENT-BASED MICROPARTICLES.
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
CN1826170B (en) * 2003-07-18 2010-12-08 巴克斯特国际公司 Process for the manufacture of small spherical particles prepared by controlled phase separation, their use and composition
US20070092452A1 (en) * 2003-07-18 2007-04-26 Julia Rashba-Step Methods for fabrication, uses, compositions of inhalable spherical particles
WO2005009375A2 (en) * 2003-07-22 2005-02-03 Baxter International Inc. Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
EP1711124A4 (en) * 2004-01-12 2011-06-01 Univ Pennsylvania LONG-TERM RELEASE PREPARATIONS AND METHODS OF USE THEREOF
US8221778B2 (en) 2005-01-12 2012-07-17 The Trustees Of The University Of Pennsylvania Drug-containing implants and methods of use thereof
WO2005112885A2 (en) 2004-05-12 2005-12-01 Baxter International Inc. Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1
US8728525B2 (en) 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
EP2335689A1 (en) 2004-05-12 2011-06-22 Baxter International Inc. Method of manufacturing nucleic acid micropheres
WO2005112893A1 (en) 2004-05-12 2005-12-01 Baxter International Inc. Microspheres comprising protein and showing injectability at high concentrations of said agent
EP1679065A1 (en) * 2005-01-07 2006-07-12 OctoPlus Sciences B.V. Controlled release compositions for interferon based on PEGT/PBT block copolymers
US20080213593A1 (en) * 2005-01-21 2008-09-04 President And Fellows Of Harvard College Systems And Methods For Forming Fluidic Droplets Encapsulated In Particles Such As Colloidal Particles
MX2009001226A (en) 2006-08-04 2009-03-20 Baxter Int Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes.
US7799225B1 (en) * 2006-09-29 2010-09-21 The United States Of America As Represented By The United States Department Of Energy Membrane contactor assisted water extraction system for separating hydrogen peroxide from a working solution, and method thereof
GB0625322D0 (en) * 2006-12-19 2007-01-24 Pharmakodex Ltd Pharmaceutical compositions
WO2009085952A1 (en) * 2007-12-20 2009-07-09 Brookwood Pharmaceuticals, Inc. Process for preparing microparticles having a low residual solvent volume
US8323685B2 (en) 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US8323615B2 (en) 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
US8367427B2 (en) 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
US8703843B2 (en) * 2008-09-11 2014-04-22 Evonik Corporation Solvent extraction microencapsulation with tunable extraction rates
ES2644885T3 (en) * 2009-01-23 2017-11-30 Evonik Corporation Continuous double emulsion procedure to manufacture microparticles
US8324830B2 (en) * 2009-02-19 2012-12-04 Microsemi Corp.—Analog Mixed Signal Group Ltd. Color management for field-sequential LCD display
US10449150B2 (en) * 2014-05-20 2019-10-22 Texas State University Fluidic system for high throughput preparation of microparticles and nanoparticles
US9439864B2 (en) * 2014-07-07 2016-09-13 Antriabio, Inc. Solvent extraction from biodegradable microparticles
FR3045591B1 (en) * 2015-12-18 2021-05-07 Suez Environnement WATER TREATMENT PROCESS, ASSOCIATED MODULE AND INSTALLATION
US10450345B2 (en) 2017-06-09 2019-10-22 General Electric Company Method of isolation of polypeptide-aptamer-polymer conjugates

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Also Published As

Publication number Publication date
US6830737B2 (en) 2004-12-14
US6471995B1 (en) 2002-10-29
WO2002026371A3 (en) 2002-05-30
US20040191324A1 (en) 2004-09-30
US20030011088A1 (en) 2003-01-16
US6884372B2 (en) 2005-04-26
WO2002026371A2 (en) 2002-04-04

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