[go: up one dir, main page]

AU2001290855A1 - Method and cell composition for screening compounds for anti-inflammatory activity - Google Patents

Method and cell composition for screening compounds for anti-inflammatory activity

Info

Publication number
AU2001290855A1
AU2001290855A1 AU2001290855A AU9085501A AU2001290855A1 AU 2001290855 A1 AU2001290855 A1 AU 2001290855A1 AU 2001290855 A AU2001290855 A AU 2001290855A AU 9085501 A AU9085501 A AU 9085501A AU 2001290855 A1 AU2001290855 A1 AU 2001290855A1
Authority
AU
Australia
Prior art keywords
inflammatory activity
cell composition
screening compounds
screening
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001290855A
Inventor
Michael C Kiefer
Allan S. Lau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetrol Biotherapeutics Inc
Original Assignee
Genetrol Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetrol Biotherapeutics Inc filed Critical Genetrol Biotherapeutics Inc
Publication of AU2001290855A1 publication Critical patent/AU2001290855A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/108—Plasmid DNA episomal vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2001290855A 2000-09-14 2001-09-13 Method and cell composition for screening compounds for anti-inflammatory activity Abandoned AU2001290855A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23238500P 2000-09-14 2000-09-14
US60232385 2000-09-14
PCT/US2001/028616 WO2002022786A1 (en) 2000-09-14 2001-09-13 Method and cell composition for screening compounds for anti-inflammatory activity

Publications (1)

Publication Number Publication Date
AU2001290855A1 true AU2001290855A1 (en) 2002-03-26

Family

ID=22872880

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001290855A Abandoned AU2001290855A1 (en) 2000-09-14 2001-09-13 Method and cell composition for screening compounds for anti-inflammatory activity

Country Status (3)

Country Link
US (2) US6864061B2 (en)
AU (1) AU2001290855A1 (en)
WO (1) WO2002022786A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0819759A2 (en) * 2007-11-26 2015-05-05 Nestec Sa Compositions and methods for inhibiting ds-rna-dependent protein kinase activation and tumor growth inhibition
EP3417701B1 (en) * 2009-10-06 2021-12-15 Regeneron Pharmaceuticals, Inc. Genetically modified mice and engraftment
SG10201601067WA (en) 2011-02-15 2016-03-30 Regeneron Pharma Humanized m-csf mice
AU2013312359B8 (en) 2012-09-07 2019-08-15 Institute For Research In Biomedicine (Irb) Genetically modified non-human animals and methods of use thereof
PT3308641T (en) 2012-11-05 2019-10-24 Univ Yale Immunodeficient, genetically modified rodent and methods of use thereof
JP6672171B2 (en) 2014-05-19 2020-03-25 リジェネロン・ファーマシューティカルズ・インコーポレイテッド Genetically modified non-human animals expressing human EPO
US20160010019A1 (en) 2014-07-14 2016-01-14 Swift Fuels, Llc Aviation fuel with a renewable oxygenate
CA2981186A1 (en) 2015-04-13 2016-10-20 Regeneron Pharmaceuticals, Inc. Humanized sirpa-il15 knockin mice and methods of use thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4535893A (en) * 1992-06-15 1994-01-04 Regents Of The University Of California, The Screening assay for the identification of immunosuppressive drugs
US5840565A (en) 1995-08-22 1998-11-24 The Regents Of The University Of California Methods for enhancing the production of viral vaccines in PKR-deficient cell culture
US6033674A (en) 1995-12-28 2000-03-07 Johns Hopkins University School Of Medicine Method of treating cancer with a tumor cell line having modified cytokine expression
US5976800A (en) 1996-06-28 1999-11-02 The Regents Of The University Of California Enhancement of cancer cell death
US6030834A (en) * 1997-12-30 2000-02-29 Chiron Corporation Human IKK-beta DNA constructs and cells
WO2000077236A2 (en) 1999-06-15 2000-12-21 Genetrol Biotherapeutics Methods for enhancing the production of cytokines in cell cultur e
US20010031859A1 (en) 1999-09-08 2001-10-18 Lau Allan S. High level cytokine production with enhanced cell viability
AU7126000A (en) 1999-09-08 2001-04-10 Genetrol Biotherapeutics, Inc. High level cytokine production with enhanced cell viability
EP1318834A2 (en) 2000-09-12 2003-06-18 Genetrol Biotherapeutics, Inc. Compositions comprising mixtures of human cytokines and methods of producing the same

Also Published As

Publication number Publication date
WO2002022786A1 (en) 2002-03-21
US20020123075A1 (en) 2002-09-05
US20050208474A1 (en) 2005-09-22
US6864061B2 (en) 2005-03-08

Similar Documents

Publication Publication Date Title
AU5520399A (en) Method and arrangement for switching cells
AU2480900A (en) Absorbent structure and method for production
AUPQ023299A0 (en) Cucurbiturils and method for synthesis
AU6111699A (en) Novel method and compounds
AU5420699A (en) Compositions suitable for electrochemical cells
AU2001253077A1 (en) Electrochemical cell and assembly for same
AU3826999A (en) Compositions suitable for electrochemical cells
AU2469901A (en) Transesterification method for making cyanoacrylates
AU2001246903A1 (en) Honeycomb structure and method for its manufacture
AU1920800A (en) Methods for designing standard cell transistor structures
AU3215500A (en) Compounds and methods
AU7989400A (en) Compounds and methods
AU3901100A (en) Method and composition for waterproofing
EP1143948A3 (en) Liver-selective glucocorticoid antagonist for treating diabetes
AU2003256710A1 (en) Auto-stimulating cells and method for making and using the same
AU5781800A (en) Methods and compositions for assaying analytes
AU3157199A (en) Structural truss
AU2832399A (en) B cell inhibitors
AU2001294342A1 (en) Porous attachment material for cells
AU2001290855A1 (en) Method and cell composition for screening compounds for anti-inflammatory activity
AU4859399A (en) Compositions and methods for treating papillomavirus-infected cells
AU1409700A (en) Method for counting living cells
AU2003296885A1 (en) Composition and method for imaging cells
AU2346800A (en) Compositions and methods using cell fusion
AU1907901A (en) Sandwich construction and method for its manufacture