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AU2001290772A1 - Alpha v integrin receptor antagonists - Google Patents

Alpha v integrin receptor antagonists

Info

Publication number
AU2001290772A1
AU2001290772A1 AU2001290772A AU9077201A AU2001290772A1 AU 2001290772 A1 AU2001290772 A1 AU 2001290772A1 AU 2001290772 A AU2001290772 A AU 2001290772A AU 9077201 A AU9077201 A AU 9077201A AU 2001290772 A1 AU2001290772 A1 AU 2001290772A1
Authority
AU
Australia
Prior art keywords
alpha
receptor antagonists
integrin receptor
integrin
antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001290772A
Inventor
Paul J. Coleman
Donghui Cui
Mark E. Duggan
Xiaojun Fang
John H. Hutchinson
Thomayant Prueksaritanont
Maria Victoria Silva Elipe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU2001290772A1 publication Critical patent/AU2001290772A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001290772A 2000-09-14 2001-09-10 Alpha v integrin receptor antagonists Abandoned AU2001290772A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23226200P 2000-09-14 2000-09-14
US60232262 2000-09-14
PCT/US2001/028404 WO2002022616A2 (en) 2000-09-14 2001-09-10 Alpha v integrin receptor antagonists

Publications (1)

Publication Number Publication Date
AU2001290772A1 true AU2001290772A1 (en) 2002-03-26

Family

ID=22872445

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001290772A Abandoned AU2001290772A1 (en) 2000-09-14 2001-09-10 Alpha v integrin receptor antagonists

Country Status (3)

Country Link
US (1) US20020040030A1 (en)
AU (1) AU2001290772A1 (en)
WO (1) WO2002022616A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2424304A1 (en) * 2000-10-05 2002-04-11 Merck & Co., Inc. Process for preparation of integrin receptor antagonist intermediates
CN102026671B (en) 2008-03-14 2014-09-03 Visen医药公司 Integrin targeting reagents and in vivo and in vitro imaging methods using the same
JP5622565B2 (en) * 2008-03-28 2014-11-12 武田薬品工業株式会社 Stable vinamidinium salts and nitrogen-containing heterocycle synthesis using them
HUE035357T2 (en) 2013-02-07 2018-05-02 Scifluor Life Sciences Inc Fluorinated integrin antagonists
US8901144B2 (en) 2013-02-07 2014-12-02 Scifluor Life Sciences, Llc Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives
GB201305668D0 (en) 2013-03-28 2013-05-15 Glaxosmithkline Ip Dev Ltd Avs6 Integrin Antagonists
LT3929196T (en) 2013-09-24 2023-09-25 Fujifilm Corporation Pharmaceutical composition of a nitrogen-containing compound or salt thereof, or metal complex thereof
GB201417011D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201417094D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201417018D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201417002D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compound
KR102647026B1 (en) 2015-02-19 2024-03-12 사이플루어 라이프 사이언시즈, 인크 Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof
GB201604680D0 (en) 2016-03-21 2016-05-04 Glaxosmithkline Ip Dev Ltd Chemical Compounds
US11046685B2 (en) 2017-02-28 2021-06-29 Morphic Therapeutic, Inc. Inhibitors of (α-v)(β-6) integrin
BR112019017929A2 (en) 2017-02-28 2020-05-19 Morphic Therapeutic Inc integrin (alpha-v) (beta-6) inhibitors
HUE071053T2 (en) 2018-08-29 2025-07-28 Morphic Therapeutic Inc Inhibitors of alpha v beta6 integrin
EP4086254B1 (en) 2018-08-29 2024-12-18 Morphic Therapeutic, Inc. Integrin inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048861A (en) * 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists
CN1284944A (en) * 1997-12-17 2001-02-21 麦克公司 Integrin receptor antagonists
HUP0302468A2 (en) * 1999-06-02 2003-11-28 Merck & Co., Inc. Alpha v integrin receptor antagonists and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US20020040030A1 (en) 2002-04-04
WO2002022616A2 (en) 2002-03-21
WO2002022616A3 (en) 2002-06-06

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