AU2001290300A1 - Method of quantifying hemoglobin and method of measuring glycation ratio of hemoglobin - Google Patents
Method of quantifying hemoglobin and method of measuring glycation ratio of hemoglobinInfo
- Publication number
- AU2001290300A1 AU2001290300A1 AU2001290300A AU9030001A AU2001290300A1 AU 2001290300 A1 AU2001290300 A1 AU 2001290300A1 AU 2001290300 A AU2001290300 A AU 2001290300A AU 9030001 A AU9030001 A AU 9030001A AU 2001290300 A1 AU2001290300 A1 AU 2001290300A1
- Authority
- AU
- Australia
- Prior art keywords
- hemoglobin
- amount
- quantifying
- sample
- measured
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000001554 Hemoglobins Human genes 0.000 title abstract 6
- 108010054147 Hemoglobins Proteins 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 230000036252 glycation Effects 0.000 title 1
- 230000003287 optical effect Effects 0.000 abstract 3
- 238000010521 absorption reaction Methods 0.000 abstract 1
- -1 tetrazolium compound Chemical class 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/723—Glycosylated haemoglobin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/904—Oxidation - reduction indicators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Plasma & Fusion (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Abstract
A method of determining Hb is provided, by which an amount of Hb can be determined easily and accurately without fear of damage to the environment. Hemoglobin in a sample is denatured with a tetrazolium compound to give denatured hemoglobin, and an amount of an optical change in the sample is measured at an absorption wavelength specific to the denatured hemoglobin. Using the amount of the optical change thus measured, an amount of the hemoglobin in the sample can be determined. The amount of the optical change preferably is measured at a wavelength in a range from 520 to 670 nm. According to this method, an amount of Hb can be determined with high accuracy as shown in FIG. 1. <IMAGE>
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000-296540 | 2000-09-28 | ||
| JP2000296540 | 2000-09-28 | ||
| PCT/JP2001/008482 WO2002027330A1 (en) | 2000-09-28 | 2001-09-27 | Method of quantifying hemoglobin and method of measuring glycation ratio of hemoglobin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001290300A1 true AU2001290300A1 (en) | 2002-04-08 |
Family
ID=18778802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001290300A Abandoned AU2001290300A1 (en) | 2000-09-28 | 2001-09-27 | Method of quantifying hemoglobin and method of measuring glycation ratio of hemoglobin |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6790665B2 (en) |
| EP (1) | EP1329721B8 (en) |
| JP (1) | JP4803696B2 (en) |
| CN (1) | CN1214246C (en) |
| AT (1) | ATE457063T1 (en) |
| AU (1) | AU2001290300A1 (en) |
| DE (1) | DE60141245D1 (en) |
| WO (1) | WO2002027330A1 (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE46105E1 (en) * | 2000-07-14 | 2016-08-16 | Arkray, Inc. | Method of selectively determining glycated hemoglobin |
| JPWO2002027331A1 (en) * | 2000-09-28 | 2004-02-05 | アークレイ株式会社 | Measurement method using redox reaction |
| DE60224839T2 (en) * | 2001-09-28 | 2009-01-29 | Arkray, Inc. | METHOD FOR STORING TETRAZOLIUM COMPOUNDS, CERTAIN STABILIZER AND TETRAZOLIUM COMPOUND BINDING SOLUTION STORED BY THE METHOD |
| JP3910174B2 (en) * | 2001-10-11 | 2007-04-25 | アークレイ株式会社 | Measurement method using sodium azide |
| ATE367583T1 (en) * | 2002-01-31 | 2007-08-15 | Arkray Inc | METHOD FOR QUANTIFYING GLYCOSYLATED PROTEIN USING A REDOX REACTION AND A QUANTIFICATION KIT |
| EP1512751B1 (en) * | 2002-05-21 | 2008-10-29 | Arkray, Inc. | Method of preventing wrong color formation of n-(carboxymethylaminocarbonyl)-4,4 -bis(dimethylamino)diphenylamine sodium, rea gent solution for the method, and measurement method employing the method |
| ATE445844T1 (en) * | 2002-06-14 | 2009-10-15 | Arkray Inc | TEST METHODS USING A SULFONIC ACID AND A NITRO COMPOUND |
| WO2004007760A1 (en) * | 2002-07-17 | 2004-01-22 | Arkray, Inc. | Method of decomposing protein with sulfonic acid compound |
| JP5131955B2 (en) * | 2004-08-05 | 2013-01-30 | 旭化成ファーマ株式会社 | Reagent containing protease reaction accelerator and / or dye stabilizer |
| EP1878801B1 (en) * | 2005-05-06 | 2011-01-26 | ARKRAY, Inc. | Protein cleavage method and use thereof |
| CN101484793B (en) * | 2006-03-24 | 2012-07-04 | 爱科来株式会社 | Glycohemoglobin concentration measuring method and concentration measuring device |
| WO2007132903A1 (en) * | 2006-05-16 | 2007-11-22 | Arkray, Inc. | Method for automatically identifying control liquid |
| JP4697809B2 (en) * | 2007-02-22 | 2011-06-08 | 旭化成ファーマ株式会社 | Method for stabilizing leuco dyes |
| WO2009067421A1 (en) * | 2007-11-20 | 2009-05-28 | Siemens Heathcare Diagnostics Inc. | Methods for the detection of glycated hemoglobin |
| JP5072776B2 (en) * | 2008-08-28 | 2012-11-14 | テルモ株式会社 | Method for the determination of hemoglobin in hemoglobin-containing liposome suspensions |
| TW201312118A (en) * | 2011-09-15 | 2013-03-16 | Toyo Boseki | Multilayer test film for measuring glycosylated hemoglobin and measuring method using it |
| BR112016019822B1 (en) * | 2014-05-06 | 2023-11-14 | Diasys Diagnostic Systems Gmbh | METHOD FOR DETERMINING THE AMOUNT OF GLYCOSYLATED HEMOGLOBIN (HBA1C) IN A SAMPLE AND REAGENT KIT |
| EP3239709B1 (en) * | 2016-04-25 | 2019-06-05 | ARKRAY, Inc. | Method of analyzing glycated protein; use of analysis reagent, analysis kit, and test piece for analysis |
| US20190346364A1 (en) * | 2016-11-18 | 2019-11-14 | Siemens Healthcare Diagnostics Inc. | Multiple sequential wavelength measurement of a liquid assay |
| AU2017378148B2 (en) * | 2016-12-16 | 2020-05-07 | Siemens Healthcare Diagnostics Inc. | Simultaneous measurement of multiple analytes of a liquid assay |
| CN109682796A (en) * | 2017-10-02 | 2019-04-26 | 爱科来株式会社 | The measurement of glycated proteins |
| CN112504985B (en) * | 2021-02-03 | 2021-06-08 | 首都医科大学附属北京友谊医院 | A method for evaluating the adverse reactions of sesquiterpenoids in curcuma oil |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60227171A (en) | 1984-04-25 | 1985-11-12 | Sogo Seibutsu Igaku Kenkyusho:Kk | Measuring method of glucose conjugated to hemoglobin |
| JPH02184758A (en) | 1989-01-11 | 1990-07-19 | Daiso Co Ltd | Method for measuring saccharogenic protein |
| JP2863491B2 (en) | 1996-06-07 | 1999-03-03 | 株式会社京都第一科学 | Reagent composition, test strip and measurement kit |
| JP3987900B2 (en) * | 1997-11-26 | 2007-10-10 | アークレイ株式会社 | Method for measuring glycated protein |
| JP2000093197A (en) | 1998-09-24 | 2000-04-04 | Hoometto:Kk | Measurement of component in liquid sample by immobilized enzyme |
| US5902731A (en) * | 1998-09-28 | 1999-05-11 | Lifescan, Inc. | Diagnostics based on tetrazolium compounds |
| US6352835B1 (en) * | 1998-11-17 | 2002-03-05 | Kyoto Daiichi Kagaku Co. Ltd. | Method of measuring substance in sample using a redox reaction |
| JP4045322B2 (en) * | 1998-11-17 | 2008-02-13 | アークレイ株式会社 | Measuring method using redox reaction |
| USRE46105E1 (en) * | 2000-07-14 | 2016-08-16 | Arkray, Inc. | Method of selectively determining glycated hemoglobin |
-
2001
- 2001-09-27 JP JP2002530858A patent/JP4803696B2/en not_active Expired - Fee Related
- 2001-09-27 US US10/380,961 patent/US6790665B2/en not_active Expired - Lifetime
- 2001-09-27 AT AT01970262T patent/ATE457063T1/en not_active IP Right Cessation
- 2001-09-27 CN CN01816508.7A patent/CN1214246C/en not_active Expired - Lifetime
- 2001-09-27 DE DE60141245T patent/DE60141245D1/en not_active Expired - Lifetime
- 2001-09-27 EP EP01970262A patent/EP1329721B8/en not_active Expired - Lifetime
- 2001-09-27 WO PCT/JP2001/008482 patent/WO2002027330A1/en not_active Ceased
- 2001-09-27 AU AU2001290300A patent/AU2001290300A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1329721B8 (en) | 2010-05-26 |
| EP1329721A4 (en) | 2006-08-23 |
| EP1329721A1 (en) | 2003-07-23 |
| CN1466684A (en) | 2004-01-07 |
| ATE457063T1 (en) | 2010-02-15 |
| JP4803696B2 (en) | 2011-10-26 |
| DE60141245D1 (en) | 2010-03-25 |
| WO2002027330A1 (en) | 2002-04-04 |
| CN1214246C (en) | 2005-08-10 |
| US6790665B2 (en) | 2004-09-14 |
| US20030186449A1 (en) | 2003-10-02 |
| EP1329721B1 (en) | 2010-02-03 |
| JPWO2002027330A1 (en) | 2004-02-05 |
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