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AU2001290177A1 - Immortalized human microglia cell and continuous cell line - Google Patents

Immortalized human microglia cell and continuous cell line

Info

Publication number
AU2001290177A1
AU2001290177A1 AU2001290177A AU9017701A AU2001290177A1 AU 2001290177 A1 AU2001290177 A1 AU 2001290177A1 AU 2001290177 A AU2001290177 A AU 2001290177A AU 9017701 A AU9017701 A AU 9017701A AU 2001290177 A1 AU2001290177 A1 AU 2001290177A1
Authority
AU
Australia
Prior art keywords
cell
immortalized human
human microglia
cell line
continuous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
AU2001290177A
Inventor
Seung U. Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2000/018777 external-priority patent/WO2002004618A1/en
Priority claimed from US09/855,468 external-priority patent/US20020064877A1/en
Application filed by University of British Columbia filed Critical University of British Columbia
Publication of AU2001290177A1 publication Critical patent/AU2001290177A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2001290177A 2000-07-10 2001-07-09 Immortalized human microglia cell and continuous cell line Withdrawn AU2001290177A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
USPCTUS0018777 2000-07-10
PCT/US2000/018777 WO2002004618A1 (en) 2000-07-10 2000-07-10 Methods of producing and using a human microglial cell line
US09/855,468 US20020064877A1 (en) 2000-07-10 2001-05-15 Methods of producing and using a human microglial cell line
US09855468 2001-05-15
US09887145 2001-06-22
US09/887,145 US6780641B2 (en) 2000-07-10 2001-06-22 Immortalized human microglia cell line
PCT/IB2001/001770 WO2002004604A2 (en) 2000-07-10 2001-07-09 Immortalized human microglia cell and continuous cell line

Publications (1)

Publication Number Publication Date
AU2001290177A1 true AU2001290177A1 (en) 2002-01-21

Family

ID=27358996

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001290177A Withdrawn AU2001290177A1 (en) 2000-07-10 2001-07-09 Immortalized human microglia cell and continuous cell line

Country Status (4)

Country Link
US (1) US6780641B2 (en)
AU (1) AU2001290177A1 (en)
CA (1) CA2383942A1 (en)
WO (1) WO2002004604A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69836853T2 (en) * 1997-03-05 2007-06-21 Japan Science And Technology Agency, Kawaguchi Established microglial cells
US20050026165A1 (en) * 2001-05-31 2005-02-03 Cindy Orser Detection of conformationally altered proteins and prions
US7166471B2 (en) 2001-05-31 2007-01-23 Arete Associates Misfolded protein sensor method in body fluids
FI20040953A0 (en) * 2004-07-08 2004-07-08 Jari Koistinaho Bone marrow cell stimulation method and bone marrow cell
ATE528649T1 (en) 2005-02-15 2011-10-15 Adlyfe Inc METHOD FOR DETECTING MISFOLDED PROTEINS AND PRIONS
CN117051096A (en) * 2017-12-08 2023-11-14 神经Gx有限责任公司 Synchronized cell cycle gene expression assays for Alzheimer's disease and related therapeutic methods
EP4549556A1 (en) 2023-10-31 2025-05-07 Vilnius University Method for generation of endocannabinoid receptor gene knockout microglia cells

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650148A (en) * 1988-12-15 1997-07-22 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system

Also Published As

Publication number Publication date
CA2383942A1 (en) 2002-01-17
US6780641B2 (en) 2004-08-24
US20030082139A1 (en) 2003-05-01
WO2002004604A2 (en) 2002-01-17

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