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AU2001286417A1 - Remote valving for microfluidic flow control - Google Patents

Remote valving for microfluidic flow control

Info

Publication number
AU2001286417A1
AU2001286417A1 AU2001286417A AU8641701A AU2001286417A1 AU 2001286417 A1 AU2001286417 A1 AU 2001286417A1 AU 2001286417 A AU2001286417 A AU 2001286417A AU 8641701 A AU8641701 A AU 8641701A AU 2001286417 A1 AU2001286417 A1 AU 2001286417A1
Authority
AU
Australia
Prior art keywords
flow control
microfluidic flow
valving
remote
remote valving
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001286417A
Inventor
Michael Mcneely
Mark Spute
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomicro Systems Inc
Original Assignee
Biomicro Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomicro Systems Inc filed Critical Biomicro Systems Inc
Publication of AU2001286417A1 publication Critical patent/AU2001286417A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
    • F15C—FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
    • F15C1/00—Circuit elements having no moving parts
    • F15C1/14—Stream-interaction devices; Momentum-exchange devices, e.g. operating by exchange between two orthogonal fluid jets ; Proportional amplifiers
    • F15C1/146—Stream-interaction devices; Momentum-exchange devices, e.g. operating by exchange between two orthogonal fluid jets ; Proportional amplifiers multiple arrangements thereof, forming counting circuits, sliding registers, integration circuits or the like
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
    • F15B—SYSTEMS ACTING BY MEANS OF FLUIDS IN GENERAL; FLUID-PRESSURE ACTUATORS, e.g. SERVOMOTORS; DETAILS OF FLUID-PRESSURE SYSTEMS, NOT OTHERWISE PROVIDED FOR
    • F15B21/00—Common features of fluid actuator systems; Fluid-pressure actuator systems or details thereof, not covered by any other group of this subclass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B1/00—Devices without movable or flexible elements, e.g. microcapillary devices
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0017—Capillary or surface tension valves, e.g. using electro-wetting or electro-capillarity effects
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0055—Operating means specially adapted for microvalves actuated by fluids
    • F16K99/0057—Operating means specially adapted for microvalves actuated by fluids the fluid being the circulating fluid itself, e.g. check valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B01L2200/146—Employing pressure sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0694—Valves, specific forms thereof vents used to stop and induce flow, backpressure valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0073—Fabrication methods specifically adapted for microvalves
    • F16K2099/0074—Fabrication methods specifically adapted for microvalves using photolithography, e.g. etching
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0073—Fabrication methods specifically adapted for microvalves
    • F16K2099/0076—Fabrication methods specifically adapted for microvalves using electrical discharge machining [EDM], milling or drilling
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0073—Fabrication methods specifically adapted for microvalves
    • F16K2099/0078—Fabrication methods specifically adapted for microvalves using moulding or stamping
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0396—Involving pressure control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y10T137/2065—Responsive to condition external of system
    • Y10T137/2071—And causing change or correction of sensed condition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y10T137/2076—Utilizing diverse fluids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y10T137/218—Means to regulate or vary operation of device
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y10T137/2224—Structure of body of device

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Fluid Mechanics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Computer Hardware Design (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
AU2001286417A 2000-08-04 2001-08-06 Remote valving for microfluidic flow control Abandoned AU2001286417A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22302200P 2000-08-04 2000-08-04
US60223022 2000-08-04
US09/922,451 US6615856B2 (en) 2000-08-04 2001-08-03 Remote valving for microfluidic flow control
US09922451 2001-08-03
PCT/US2001/024643 WO2002012734A1 (en) 2000-08-04 2001-08-06 Remote valving for microfluidic flow control

Publications (1)

Publication Number Publication Date
AU2001286417A1 true AU2001286417A1 (en) 2002-02-18

Family

ID=26917356

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001286417A Abandoned AU2001286417A1 (en) 2000-08-04 2001-08-06 Remote valving for microfluidic flow control

Country Status (7)

Country Link
US (1) US6615856B2 (en)
EP (1) EP1313955A4 (en)
JP (1) JP2004506146A (en)
KR (1) KR20030059797A (en)
AU (1) AU2001286417A1 (en)
CA (1) CA2417217A1 (en)
WO (1) WO2002012734A1 (en)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2278612C2 (en) * 2000-07-14 2006-06-27 Лайфскен, Инк. Immune sensor
FR2813207B1 (en) * 2000-08-28 2002-10-11 Bio Merieux REACTIONAL CARD AND USE OF SUCH A CARD
US6805841B2 (en) * 2001-05-09 2004-10-19 The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Liquid pumping system
US6729352B2 (en) 2001-06-07 2004-05-04 Nanostream, Inc. Microfluidic synthesis devices and methods
FR2833699B1 (en) * 2001-12-19 2004-05-28 Bio Merieux METHOD FOR CHECKING THE PRESENCE OR ABSENCE OR CHECKING THE FILLING OF A CONTAINER AND DEVICE FOR IMPLEMENTING THE METHOD
US7459127B2 (en) 2002-02-26 2008-12-02 Siemens Healthcare Diagnostics Inc. Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces
US20060134713A1 (en) 2002-03-21 2006-06-22 Lifescan, Inc. Biosensor apparatus and methods of use
US20030180814A1 (en) * 2002-03-21 2003-09-25 Alastair Hodges Direct immunosensor assay
FR2841158B1 (en) * 2002-06-24 2007-02-23 Bio Merieux THERMO-PNEUMATICALLY FLEXIBLE FLUID DEVICE ISOLATION AND POSSIBLY AGITATION OF THE CONTENT OF AN OPERATIVE CAVITY
US20040042930A1 (en) * 2002-08-30 2004-03-04 Clemens Charles E. Reaction chamber with capillary lock for fluid positioning and retention
JP4210783B2 (en) * 2002-09-26 2009-01-21 アークレイ株式会社 Analysis tool
EP1567796B1 (en) * 2002-12-04 2008-05-28 Spinx, Inc. Devices and methods for programmable microscale manipulation of fluids
DE10302720A1 (en) * 2003-01-23 2004-08-05 Steag Microparts Gmbh Microfluidic switch for stopping the flow of fluid during a time interval
FR2855076B1 (en) * 2003-05-21 2006-09-08 Inst Curie MICROFLUIDIC DEVICE
US20080257754A1 (en) * 2003-06-27 2008-10-23 Pugia Michael J Method and apparatus for entry of specimens into a microfluidic device
CA2479452C (en) * 2003-08-30 2008-11-04 F.Hoffmann-La Roche Ag Method and device for determining analytes in a liquid
JP4286094B2 (en) * 2003-09-24 2009-06-24 オリンパス株式会社 Reactor for biological materials
US8101431B2 (en) * 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US20050210996A1 (en) * 2004-03-12 2005-09-29 Quinn John G Flow channel structure and method
US20050220644A1 (en) * 2004-03-31 2005-10-06 Sebastian Bohm Pneumatic actuator for bolus generation in a fluid handling circuit
US20080069729A1 (en) * 2005-02-16 2008-03-20 Mcneely Michael R Liquid Valving Using Reactive or Responsive Materials
WO2006099042A2 (en) * 2005-03-09 2006-09-21 The Regents Of The University Of California Microfluidic valve for liquids
KR100663652B1 (en) * 2005-04-26 2007-01-02 김계열 tongs
WO2006122311A2 (en) * 2005-05-11 2006-11-16 The Trustees Of The University Of Pennsylvania Microfluidic chip
US7935318B2 (en) * 2005-06-13 2011-05-03 Hewlett-Packard Development Company, L.P. Microfluidic centrifugation systems
JP4721414B2 (en) * 2005-08-15 2011-07-13 キヤノン株式会社 REACTION CARTRIDGE, REACTOR, AND METHOD FOR TRANSFERRING REACTION CARTRIDGE SOLUTION
US8172455B2 (en) * 2005-10-28 2012-05-08 Arkray, Inc. Liquid feeding method and cartridge to be used therein
CN101004423B (en) * 2006-01-19 2011-12-28 博奥生物有限公司 Card, kit system in use for analyzing sample of liquid
US20100200021A1 (en) * 2006-02-17 2010-08-12 Nils Adey Slide Conditioning Systems and Methods
US7897113B2 (en) * 2006-07-17 2011-03-01 Industrial Technology Research Institute Fluidic devices and controlling methods thereof
US20080032311A1 (en) * 2006-08-04 2008-02-07 Zhenghua Ji Low volume mixing of sample
US20080031089A1 (en) * 2006-08-04 2008-02-07 Zhenghua Ji Low-volume mixing of sample
CN101135650A (en) * 2006-08-29 2008-03-05 彭兴跃 Cell observation experimental method and device thereof
FR2907228B1 (en) * 2006-10-13 2009-07-24 Rhodia Recherches & Tech FLUID FLOW DEVICE, ASSEMBLY FOR DETERMINING AT LEAST ONE CHARACTERISTIC OF A PHYSICO-CHEMICAL SYSTEM COMPRISING SUCH A DEVICE, DETERMINING METHOD AND CORRESPONDING SCREENING METHOD
EP2111551A1 (en) * 2006-12-20 2009-10-28 Applied Biosystems, LLC Devices and methods for flow control in microfluidic structures
JP5012817B2 (en) * 2007-02-05 2012-08-29 株式会社島津製作所 Reaction vessel plate and reaction processing method
US8016260B2 (en) 2007-07-19 2011-09-13 Formulatrix, Inc. Metering assembly and method of dispensing fluid
DK2180951T3 (en) * 2007-08-21 2019-12-02 Belimo Holding Ag FLOW SENSOR AND PREPARATION PROCEDURE
US7736891B2 (en) * 2007-09-11 2010-06-15 University Of Washington Microfluidic assay system with dispersion monitoring
JP4826570B2 (en) * 2007-10-19 2011-11-30 株式会社島津製作所 Gas flow switching device
EP2127747A1 (en) * 2008-05-20 2009-12-02 F.Hoffmann-La Roche Ag Microfluid analytical device comprising a valve with swellable material
US20100167943A1 (en) * 2008-06-09 2010-07-01 Nils Adey System and Method for Hybridization Slide Processing
US20110190153A1 (en) * 2008-06-09 2011-08-04 Nils Adey System and method for hybridization slide processing
US8122901B2 (en) * 2008-06-30 2012-02-28 Canon U.S. Life Sciences, Inc. System and method for microfluidic flow control
US8501115B2 (en) * 2008-10-24 2013-08-06 Statspin, Inc. Modular system for performing laboratory protocols and associated methods
US8100293B2 (en) 2009-01-23 2012-01-24 Formulatrix, Inc. Microfluidic dispensing assembly
DE102009000529A1 (en) * 2009-01-30 2010-08-19 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Microfluidic chip with pressure measuring device
KR101602414B1 (en) 2009-03-16 2016-03-11 삼성전자주식회사 Apparatus for fluidic control
DE102009015395B4 (en) 2009-03-23 2022-11-24 Thinxxs Microtechnology Gmbh Flow cell for treating and/or examining a fluid
US20100300563A1 (en) * 2009-05-27 2010-12-02 John Ramunas Modular device and method for moving fluids to and from a sample delivery element
WO2012153192A2 (en) * 2011-05-06 2012-11-15 Owe Orwar Microfluidic device with holding interface, and method of use
TWI410617B (en) * 2009-12-28 2013-10-01 Univ Feng Chia Air Control Microflow Detection Device
WO2011139888A2 (en) 2010-04-29 2011-11-10 Statspin, Inc. Analytical system for performing laboratory protocols and associated methods
US8721061B2 (en) 2010-05-21 2014-05-13 Hewlett-Packard Development Company, L.P. Fluid ejection device with circulation pump
US9090084B2 (en) 2010-05-21 2015-07-28 Hewlett-Packard Development Company, L.P. Fluid ejection device including recirculation system
US9963739B2 (en) 2010-05-21 2018-05-08 Hewlett-Packard Development Company, L.P. Polymerase chain reaction systems
US10132303B2 (en) 2010-05-21 2018-11-20 Hewlett-Packard Development Company, L.P. Generating fluid flow in a fluidic network
US9395050B2 (en) 2010-05-21 2016-07-19 Hewlett-Packard Development Company, L.P. Microfluidic systems and networks
US8460607B2 (en) 2010-10-22 2013-06-11 Abbott Laboratories Microfluidic device having a flow channel
JP6138173B2 (en) 2012-03-09 2017-05-31 ライカ バイオシステムズ リッチモンド インコーポレイテッドＬｅｉｃａ Ｂｉｏｓｙｓｔｅｍｓ Ｒｉｃｈｍｏｎｄ， Ｉｎｃ． Method and apparatus for controlling temperature in a dynamic fluid in a laboratory sample processing system
US9180449B2 (en) * 2012-06-12 2015-11-10 Hach Company Mobile water analysis
DE102013009347A1 (en) 2013-06-04 2014-12-04 Hydrometer Gmbh Flowmeter
EP2896457B1 (en) * 2014-01-15 2017-08-23 IMEC vzw Microstructured micropillar arrays for controllable filling of a capillary pump
EP3137030B1 (en) 2014-04-30 2019-06-12 Kimberly-Clark Worldwide, Inc. Absorbent article including a fluid distributing structure
CN107075431B (en) * 2014-08-15 2020-08-07 惠普发展公司，有限责任合伙企业 microfluidic valve
WO2016092333A2 (en) * 2014-12-12 2016-06-16 Bio Amd Holdings Limited Assay apparatus
US12290811B2 (en) 2015-01-23 2025-05-06 Unchained Labs Microfluidic serial dilution platform based well-plate using an oil-free immiscible phase driven by manual or electronic pipettors
US10828639B2 (en) 2015-04-30 2020-11-10 Hewlett-Packard Development Company L.P. Target constituent location and discharge
US10981166B2 (en) 2015-06-11 2021-04-20 Neofluidics Llc Manual or electronic pipette driven well plate for nano-liter droplet storage and methods of using same
GB201617869D0 (en) 2016-10-21 2016-12-07 Blacktrace Holdings Limited A microfluidic device
WO2018200896A1 (en) 2017-04-28 2018-11-01 Neofluidics, Llc Fluidic devices with reaction wells and uses thereof
CA3072328A1 (en) 2017-08-09 2019-02-14 Neofluidics, Llc Devices and methods for bioassay
US11305279B2 (en) 2017-11-10 2022-04-19 Neofluidics, Llc Integrated fluidic circuit and device for droplet manipulation and methods thereof
US10046322B1 (en) 2018-03-22 2018-08-14 Talis Biomedical Corporation Reaction well for assay device
CN108716938B (en) * 2018-04-27 2024-06-07 广州万孚生物技术股份有限公司 Liquid quantifying device and application thereof
EP3870369A4 (en) 2018-10-26 2022-11-09 Neofluidics, LLC Fluidic devices with reaction wells and constriction channels and uses thereof
US11008627B2 (en) 2019-08-15 2021-05-18 Talis Biomedical Corporation Diagnostic system
CN115722279B (en) * 2021-08-31 2025-08-26 湖南乐准智芯生物科技有限公司 Microfluidic chip and detection device and control method thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4426451A (en) * 1981-01-28 1984-01-17 Eastman Kodak Company Multi-zoned reaction vessel having pressure-actuatable control means between zones
US4676274A (en) * 1985-02-28 1987-06-30 Brown James F Capillary flow control
US5637469A (en) * 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
DE4220077A1 (en) 1992-06-19 1993-12-23 Bosch Gmbh Robert Micro-pump for delivery of gases - uses working chamber warmed by heating element and controlled by silicon wafer valves.
US5789045A (en) * 1994-04-15 1998-08-04 The United States Of America As Represented By The Secretary Of The Air Force Microtubes devices based on surface tension and wettability
US6152181A (en) * 1992-11-16 2000-11-28 The United States Of America As Represented By The Secretary Of The Air Force Microdevices based on surface tension and wettability that function as sensors, actuators, and other devices
DE4405005A1 (en) * 1994-02-17 1995-08-24 Rossendorf Forschzent Micro fluid diode
JP4308320B2 (en) 1995-03-07 2009-08-05 ビービーアイ バイオセック インコーポレーテッド Pressure cycling reactor
US6168948B1 (en) 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US6130098A (en) 1995-09-15 2000-10-10 The Regents Of The University Of Michigan Moving microdroplets
EP0862708A4 (en) 1995-12-18 1998-11-25 Armand P Neukermans Microfluidic valve and integrated microfluidic system
US5830657A (en) 1996-05-01 1998-11-03 Visible Genetics Inc. Method for single-tube sequencing of nucleic acid polymers
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US5863801A (en) 1996-06-14 1999-01-26 Sarnoff Corporation Automated nucleic acid isolation
US6136212A (en) 1996-08-12 2000-10-24 The Regents Of The University Of Michigan Polymer-based micromachining for microfluidic devices
US5865308A (en) * 1996-10-29 1999-02-02 Baxter International Inc. System, method and device for controllably releasing a product
AU727083B2 (en) * 1997-04-25 2000-11-30 Caliper Life Sciences, Inc. Microfluidic devices incorporating improved channel geometries
AU2347799A (en) 1998-01-29 1999-08-16 University Of Pittsburgh Thermal expansion-induced fluid control for microfluidic devices
CA2347182C (en) * 1998-10-13 2004-06-15 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
FR2790683B1 (en) 1999-03-09 2001-05-11 Biomerieux Sa DEVICE AND METHOD FOR POSITIONING A LIQUID
EP1187677B1 (en) 1999-06-22 2003-11-26 Agilent Technologies, Inc. (a Delaware corporation) Apparatus for the operation of a microfluidic device
JP2003506679A (en) 1999-07-28 2003-02-18 ユニバーシテイ オブ ワシントン Fluid interconnects, interconnect manifolds and microfluidic devices for internal delivery of gas and application of reduced pressure

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