AU2001280954A1 - Production of lysosomal enzymes in plants by transient expression - Google Patents
Production of lysosomal enzymes in plants by transient expressionInfo
- Publication number
- AU2001280954A1 AU2001280954A1 AU2001280954A AU8095401A AU2001280954A1 AU 2001280954 A1 AU2001280954 A1 AU 2001280954A1 AU 2001280954 A AU2001280954 A AU 2001280954A AU 8095401 A AU8095401 A AU 8095401A AU 2001280954 A1 AU2001280954 A1 AU 2001280954A1
- Authority
- AU
- Australia
- Prior art keywords
- plants
- production
- transient expression
- lysosomal enzymes
- lysosomal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 230000002132 lysosomal effect Effects 0.000 title 1
- 230000010474 transient expression Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01045—Glucosylceramidase (3.2.1.45), i.e. beta-glucocerebrosidase
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- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
- C12N15/8203—Virus mediated transformation
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- C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
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- C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
- C12N9/0059—Catechol oxidase (1.10.3.1), i.e. tyrosinase
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- C12N9/18—Carboxylic ester hydrolases (3.1.1)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/626,127 US6846968B1 (en) | 1988-02-26 | 2000-07-26 | Production of lysosomal enzymes in plants by transient expression |
| US09/626,127 | 2000-07-26 | ||
| PCT/US2001/024111 WO2002008404A2 (en) | 2000-07-26 | 2001-07-26 | Production of lysosomal enzymes in plants by transient expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001280954A1 true AU2001280954A1 (en) | 2002-02-05 |
Family
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Family Applications (1)
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|---|---|---|---|
| AU2001280954A Abandoned AU2001280954A1 (en) | 2000-07-26 | 2001-07-26 | Production of lysosomal enzymes in plants by transient expression |
Country Status (3)
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| US (7) | US6846968B1 (en) |
| AU (1) | AU2001280954A1 (en) |
| WO (1) | WO2002008404A2 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| IL155588A0 (en) * | 2003-04-27 | 2003-11-23 | Metabogal Ltd | Methods for expression of enzymatically active recombinant lysosomal enzymes in transgenic plant root cells and vectors used thereby |
| US20050032211A1 (en) * | 1996-09-26 | 2005-02-10 | Metabogal Ltd. | Cell/tissue culturing device, system and method |
| US6906172B2 (en) | 1998-03-10 | 2005-06-14 | Large Scale Biology Corporation | Flexible processing apparatus for isolating and purifying viruses, soluble proteins and peptides from plant sources |
| US20030100945A1 (en) | 2001-11-23 | 2003-05-29 | Mindguard Ltd. | Implantable intraluminal device and method of using same in treating aneurysms |
| ITRM20020115A1 (en) * | 2002-03-01 | 2003-09-01 | Plantechno S R L | EXPRESSION OF LYSOSOMIAL ENZYMES IN SEED. |
| US7951557B2 (en) * | 2003-04-27 | 2011-05-31 | Protalix Ltd. | Human lysosomal proteins from plant cell culture |
| AU2007201909C1 (en) * | 2003-04-27 | 2011-12-01 | Protalix Ltd. | Production of High Mannose Proteins in Plant Culture |
| US20100196345A1 (en) * | 2003-04-27 | 2010-08-05 | Protalix | Production of high mannose proteins in plant culture |
| CN1922306B (en) * | 2004-02-20 | 2010-10-06 | 美国弗劳恩霍夫股份有限公司 | Systems and methods for clonal expression in plants |
| CA2626092A1 (en) | 2005-11-18 | 2007-05-24 | Tokyo Metropolitan Organization For Medical Research | Novel highly functional enzyme having modified substrate-specificity |
| US20080248512A1 (en) * | 2006-09-12 | 2008-10-09 | Genzyme Corporation | Methods for detection of lysosomal storage disease |
| KR101553040B1 (en) * | 2007-05-07 | 2015-09-14 | 프로탈릭스 리미티드 | Large scale disposable bioreactor |
| ES2549121T3 (en) * | 2007-05-18 | 2015-10-23 | Tokyo Metropolitan Institute Of Medical Science | Pharmaceutical composition for enzyme replacement therapy |
| EP2192924B1 (en) * | 2007-08-20 | 2017-10-11 | Protalix Ltd. | Saccharide-containing protein conjugates and uses thereof |
| US9194011B2 (en) | 2009-11-17 | 2015-11-24 | Protalix Ltd. | Stabilized alpha-galactosidase and uses thereof |
| JP5913372B2 (en) | 2011-01-20 | 2016-04-27 | プロタリクス リミテッド | Nucleic acid expression constructs for the expression of α-galactosidase in plants and plant cells |
| TWI620816B (en) * | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | Plant derived protein recovery method |
| US20130347144A1 (en) * | 2012-04-10 | 2013-12-26 | Prairie Plant Systems Inc. | Promoters and methods for transforming tubers and transformed tubers |
| ES2999332T3 (en) | 2012-09-19 | 2025-02-25 | Gemvax & Kael Co Ltd | Cell penetrating peptide, conjugate comprising the same, and composition comprising conjugate |
| WO2015013116A1 (en) * | 2013-07-25 | 2015-01-29 | Merck Sharp & Dohme Corp. | Method for reducing the extent of o-mannosylation of glycoproteins |
| JP2017534640A (en) * | 2014-11-10 | 2017-11-24 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | Alpha-L-iduronidase, iduronic acid-2-sulfatase and alpha-galactosidase A therapeutic compositions and methods for their use |
| JP6650943B2 (en) | 2014-12-22 | 2020-02-19 | コデクシス, インコーポレイテッド | Human α-galactosidase variant |
| JP6936150B2 (en) | 2015-03-17 | 2021-09-15 | エレヴァ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングeleva GmbH | Glycosylated lysosomal protein, its production method and use |
| GB201508025D0 (en) | 2015-05-11 | 2015-06-24 | Ucl Business Plc | Fabry disease gene therapy |
| US20210348204A1 (en) * | 2018-10-16 | 2021-11-11 | Trait Biosciences, Inc. | Systems, Methods, And Compositions For The Production of Water-Soluble Terpenes Derived From Cannabis Plants |
| MY207075A (en) | 2018-12-20 | 2025-01-28 | Codexis Inc | Human alpha-galactosidase variants |
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| US4921902A (en) * | 1984-02-02 | 1990-05-01 | The Dow Chemical Company | Hydrophobie associative composition containing a polymer of a water-soluble monomer and an amphiphilic monomer |
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| US5179023A (en) | 1989-03-24 | 1993-01-12 | Research Corporation Technologies, Inc. | Recombinant α-galactosidase a therapy for Fabry disease |
| US5401650A (en) * | 1990-10-24 | 1995-03-28 | The Mount Sinai School Of Medicine Of The City University Of New York | Cloning and expression of biologically active α-galactosidase A |
| US5356804A (en) * | 1990-10-24 | 1994-10-18 | Mount Sinai School Of Medicine Of The City Of New York | Cloning and expression of biologically active human α-galactosidase A |
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| CA2231861A1 (en) | 1995-09-13 | 1997-03-20 | Takanori Oka | Method for concentrating mutant nucleic acid and nucleic acid-concentrating assay kit for said concentration method |
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| DE69739233D1 (en) | 1996-06-25 | 2009-03-12 | Pepscan Systems Bv | A VACCINE CONTAINING LABELS BONDED TO A CARRIER CONTAINING ANTIGEN |
| US6042832A (en) | 1996-08-28 | 2000-03-28 | Thomas Jefferson University | Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins |
| US6210666B1 (en) | 1997-10-21 | 2001-04-03 | Orphan Medical, Inc. | Truncated α-galactosidase A to treat fabry disease |
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-
2000
- 2000-07-26 US US09/626,127 patent/US6846968B1/en not_active Expired - Fee Related
-
2001
- 2001-07-26 AU AU2001280954A patent/AU2001280954A1/en not_active Abandoned
- 2001-07-26 WO PCT/US2001/024111 patent/WO2002008404A2/en not_active Ceased
- 2001-11-13 US US09/993,059 patent/US6887696B2/en not_active Expired - Fee Related
-
2002
- 2002-03-20 US US10/103,327 patent/US6890748B2/en not_active Expired - Fee Related
-
2003
- 2003-06-23 US US10/602,219 patent/US20040016021A1/en not_active Abandoned
- 2003-06-23 US US10/602,220 patent/US20040023281A1/en not_active Abandoned
-
2004
- 2004-05-21 US US10/851,388 patent/US20040234516A1/en not_active Abandoned
- 2004-11-08 US US10/984,389 patent/US20050125859A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20050125859A1 (en) | 2005-06-09 |
| US20020088024A1 (en) | 2002-07-04 |
| US6887696B2 (en) | 2005-05-03 |
| US20040234516A1 (en) | 2004-11-25 |
| WO2002008404A2 (en) | 2002-01-31 |
| US20040016021A1 (en) | 2004-01-22 |
| US6846968B1 (en) | 2005-01-25 |
| US20040023281A1 (en) | 2004-02-05 |
| WO2002008404A3 (en) | 2003-04-03 |
| US6890748B2 (en) | 2005-05-10 |
| US20030106095A1 (en) | 2003-06-05 |
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