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AU2001278739A1 - Method of modifying microorganism-origin transglutaminase - Google Patents

Method of modifying microorganism-origin transglutaminase

Info

Publication number
AU2001278739A1
AU2001278739A1 AU2001278739A AU7873901A AU2001278739A1 AU 2001278739 A1 AU2001278739 A1 AU 2001278739A1 AU 2001278739 A AU2001278739 A AU 2001278739A AU 7873901 A AU7873901 A AU 7873901A AU 2001278739 A1 AU2001278739 A1 AU 2001278739A1
Authority
AU
Australia
Prior art keywords
microorganism
modifying
transglutaminase
origin
origin transglutaminase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001278739A
Inventor
Kazuo Hirayama
Kohki Ishikawa
Tatsuki Kashiwagi
Nobuhisa Shimba
Ei-Ichiro Suzuki
Keiichi Yokoyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of AU2001278739A1 publication Critical patent/AU2001278739A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/02—Aminoacyltransferases (2.3.2)
    • C12Y203/02013—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2001278739A 2000-08-17 2001-08-15 Method of modifying microorganism-origin transglutaminase Abandoned AU2001278739A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2000-247664 2000-08-17
JP2000247664 2000-08-17
JP2000-396695 2000-12-27
JP2000396695 2000-12-27
PCT/JP2001/007038 WO2002014518A1 (en) 2000-08-17 2001-08-15 Method of modifying microorganism-origin transglutaminase

Publications (1)

Publication Number Publication Date
AU2001278739A1 true AU2001278739A1 (en) 2002-02-25

Family

ID=26598044

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001278739A Abandoned AU2001278739A1 (en) 2000-08-17 2001-08-15 Method of modifying microorganism-origin transglutaminase

Country Status (9)

Country Link
US (2) US20040002144A1 (en)
EP (1) EP1310560A4 (en)
KR (1) KR100575394B1 (en)
CN (1) CN1275980C (en)
AU (1) AU2001278739A1 (en)
BR (1) BR0113304A (en)
CA (1) CA2419453C (en)
RU (1) RU2260051C2 (en)
WO (1) WO2002014518A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7485438B2 (en) 2002-03-01 2009-02-03 Szu-Yi Chou Method of producing polyvalent antigens
US7101695B2 (en) 2002-03-01 2006-09-05 Szu-Yi Chou Method of producing transglutaminase having broad substrate activity
CN101263225A (en) * 2005-08-18 2008-09-10 诺沃-诺迪斯克保健股份有限公司 Improved substrate specificity of transglutaminase
US20090318349A1 (en) * 2006-08-18 2009-12-24 Novo Nordisk Health Care Ag Transglutaminase variants with improved specificity
NZ579599A (en) 2007-02-15 2012-03-30 Ajinomoto Kk Transglutaminase having disulfide bond introduced therein
US20100099610A1 (en) * 2007-02-22 2010-04-22 Novo Nordisk Health Care Ag Transglutaminase Variants with Improved Specificity
DE102007042727A1 (en) * 2007-09-07 2009-09-24 Martin-Luther-Universität Halle-Wittenberg Thermostable transglutaminases
EP2404999B1 (en) * 2009-03-06 2015-04-29 Ajinomoto Co., Inc. Thermotolerant transglutaminase originating in actinomyces
MY177148A (en) * 2014-06-12 2020-09-08 Cspc Megalith Biopharmaceutical Co Ltd Homogenous antibody drug conjugates via enzymatic methods
US11319531B2 (en) 2017-11-07 2022-05-03 Codexis, Inc. Transglutaminase variants
EP3719131A4 (en) * 2017-11-30 2021-09-01 Amano Enzyme Inc. MODIFIED TRANSGLUTAMINASE
US20230125821A1 (en) * 2020-03-03 2023-04-27 Amano Enzyme Inc. Modified transglutaminase
MX2022011077A (en) * 2020-03-13 2022-09-23 Curie Co Inc Transglutaminase variants.
BR112022021955A2 (en) * 2020-05-13 2022-12-13 Curie Co Inc TRANSGLUTAMINASE VARIANTS AND APPLICATIONS FOR THEIR USE
EP4170034A4 (en) * 2020-06-18 2024-07-17 Amano Enzyme Inc. Novel transglutaminase
FR3117599B1 (en) * 2020-12-16 2024-11-29 Oreal Method of prognosis and/or diagnosis of a dandruff condition of the scalp
CN114220492B (en) * 2021-12-16 2023-02-28 江南大学 Method and application of enzyme redesign based on isothermal compressibility coefficient perturbation and mutants screened by this method

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665280B2 (en) * 1987-03-04 1994-08-24 味の素株式会社 Protein gelling agent and protein gelling method using the same
US5643758A (en) * 1987-03-10 1997-07-01 New England Biolabs, Inc. Production and purification of a protein fused to a binding protein
NZ234453A (en) 1989-07-13 1993-01-27 Sanofi Sa Recombinant dna encoding urate oxidase, and vector, host, protein and pharmaceutical compositions associated therewith
JP2849773B2 (en) * 1990-08-27 1999-01-27 天野製薬株式会社 Method for producing transglutaminase from Streptomyces
EP0481504B1 (en) * 1990-10-19 1996-01-17 Amano Pharmaceutical Co., Ltd. Recombinant transglutaminase
US5965442A (en) * 1993-11-12 1999-10-12 Nec Corporation Method of altering enzymes and a novel neopullulanase
US6100053A (en) * 1994-08-26 2000-08-08 Novo Nordisk A/S Microbial transglutaminases, their production and use
US5965402A (en) * 1996-02-20 1999-10-12 Smithkline Beecham Corporation DNA encoding phoH polypeptides
EP0889133B1 (en) * 1997-07-04 2004-03-10 Ajinomoto Co., Inc. Process for producing microbial transglutaminase
DE19814860A1 (en) * 1998-04-02 1999-10-07 Fuchsbauer Hans Lothar Bacterial transglutaminases
WO2000070026A1 (en) * 1999-05-14 2000-11-23 Wisconsin Alumni Research Foundation A NOVEL TRANSGLUTAMINASE FROM $i(STREPTOVERTICILLIUM MOBARAENS)
AU7449400A (en) * 1999-09-30 2001-04-30 Ajinomoto Co., Inc. Process for producing transglutaminase
US20020187525A1 (en) * 1999-10-18 2002-12-12 Ajinomoto Co., Inc. Method of producing microbial transglutaminase

Also Published As

Publication number Publication date
WO2002014518A1 (en) 2002-02-21
US20060275872A1 (en) 2006-12-07
CN1275980C (en) 2006-09-20
CA2419453A1 (en) 2003-02-14
BR0113304A (en) 2004-01-06
US7553650B2 (en) 2009-06-30
EP1310560A1 (en) 2003-05-14
US20040002144A1 (en) 2004-01-01
CN1469929A (en) 2004-01-21
KR100575394B1 (en) 2006-05-03
KR20030027037A (en) 2003-04-03
RU2260051C2 (en) 2005-09-10
EP1310560A4 (en) 2005-07-13
CA2419453C (en) 2010-03-09

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