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AU2001275048A1 - Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof - Google Patents

Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof

Info

Publication number
AU2001275048A1
AU2001275048A1 AU2001275048A AU7504801A AU2001275048A1 AU 2001275048 A1 AU2001275048 A1 AU 2001275048A1 AU 2001275048 A AU2001275048 A AU 2001275048A AU 7504801 A AU7504801 A AU 7504801A AU 2001275048 A1 AU2001275048 A1 AU 2001275048A1
Authority
AU
Australia
Prior art keywords
polyene macrolide
group
compound
alkyl
polyene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001275048A
Other languages
English (en)
Inventor
Christopher J. Baldwin
Conway C. Chang
Binh T. Dang
David J. Loury
Reyna J Simon
Robert R. Webb Ii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biowest Therapeutics Inc
Original Assignee
IntraBiotics Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IntraBiotics Pharmaceuticals Inc filed Critical IntraBiotics Pharmaceuticals Inc
Publication of AU2001275048A1 publication Critical patent/AU2001275048A1/en
Assigned to MICROLOGIX BIOTECH INC. reassignment MICROLOGIX BIOTECH INC. Request for Assignment Assignors: INTRABIOTICS PHARMACEUTICALS, INC.
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU2001275048A 2000-05-31 2001-05-31 Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof Abandoned AU2001275048A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20765900P 2000-05-31 2000-05-31
US60207659 2000-05-31
US09/870,071 US6664241B2 (en) 2000-05-31 2001-05-29 Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof
US09870071 2001-05-29
PCT/US2001/017535 WO2001091758A1 (fr) 2000-05-31 2001-05-31 Derives amides hydrosolubles de macrolides polyenes et leur preparation et utilisation

Publications (1)

Publication Number Publication Date
AU2001275048A1 true AU2001275048A1 (en) 2001-12-11

Family

ID=26902450

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001275048A Abandoned AU2001275048A1 (en) 2000-05-31 2001-05-31 Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof

Country Status (6)

Country Link
US (2) US6664241B2 (fr)
EP (1) EP1313487A4 (fr)
JP (1) JP2003534382A (fr)
AU (1) AU2001275048A1 (fr)
CA (1) CA2410886A1 (fr)
WO (1) WO2001091758A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2394833A1 (fr) * 2000-01-14 2001-07-19 Binh T. Dang Derives de macrolides de polyene, preparation et utilisations correspondantes
US20050272166A1 (en) * 2004-05-06 2005-12-08 Li Jin Methods and systems for detection, identification and quantitation of macrolides and their impurities
WO2008143730A2 (fr) * 2007-02-28 2008-11-27 Rib-X Pharmaceuticals, Inc. Composés macrolides et procédés pour leur fabrication et leur utilisation
GB0712881D0 (en) * 2007-07-03 2007-08-15 Biosergen As Compounds
WO2009015541A1 (fr) * 2007-07-30 2009-02-05 Shanghai Institute Of Pharmaceutical Industry Antibiotiques à base de diesters de polyènes
MX365184B (es) * 2010-12-21 2019-05-21 Centro De Investig Y De Estudios Avanzados Del I P N Nuevos compuestos analogos de la anfotericina y composiciones farmaceuticas que los contienen.
KR101379978B1 (ko) 2011-12-30 2014-04-02 인하대학교 산학협력단 신규 폴리엔 화합물, 이의 제조방법 및 이를 유효성분으로 포함하는 항진균제
IN2014DN07481A (fr) 2012-03-09 2015-04-24 Blirt S A
AU2013276480B2 (en) * 2012-06-15 2018-01-04 Blirt S.A. N-substituted second generation derivatives of antifungal antibiotic Amphotericin B and methds of their preparation and application
WO2016112243A1 (fr) * 2015-01-08 2016-07-14 The Board Of Trustees Of The University Of Illinois Dérivés d'urée de l'amphotéricine b dérivée d'amines secondaires
CA3213127A1 (fr) 2015-04-15 2016-10-20 Sfunga Therapeutics, Inc. Derives d'amphotericine b
EP3917939A1 (fr) * 2019-01-31 2021-12-08 Sigma-Aldrich Co. LLC Agents antifongiques ayant une solubilité aqueuse améliorée
EP4009985A4 (fr) * 2019-08-08 2023-09-06 The Board Of Trustees Of The University Of Illinois Dérivés amides hybrides d'amphotéricine b
WO2022035752A1 (fr) * 2020-08-10 2022-02-17 The Board Of Trustees Of The University Of Illinois Dérivés amides hybrides d'amphotéricine b
CN111909226A (zh) * 2020-08-11 2020-11-10 深圳市儿童医院 一种葡萄糖酸修饰的两性霉素b衍生物及其用途
CN111875653A (zh) * 2020-08-11 2020-11-03 深圳市儿童医院 一种含二硫键的两性霉素b衍生物及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60877C (fi) * 1971-08-13 1982-04-13 Politechnika Gdanska Foerfarande foer framstaellning av terapeutiskt aktiva i vatten laett dispergerbara polyenmakrolidantibiot-n-glykosylderivat
PL122086B1 (en) 1979-04-09 1982-06-30 Politechnika Gdanska Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh
PL124710B1 (en) 1979-07-18 1983-02-28 Politechnika Gdanska Process for preparing esters of antibiotics from polyene macrolids group and their n-substituted derivatives
FR2654339B1 (fr) * 1989-11-14 1994-10-28 Mayoly Spindler Laboratoires Nouveaux derives solubles et non toxiques des macrolides polyeniques basiques, leur preparation et leurs applications.
IT1237772B (it) 1989-11-16 1993-06-17 Tiberio Bruzzese Derivati di macrolidi polienici.
IT1243404B (it) 1990-12-03 1994-06-10 Prodotti Antibiotici Spa Derivati della partricina
CA2394833A1 (fr) * 2000-01-14 2001-07-19 Binh T. Dang Derives de macrolides de polyene, preparation et utilisations correspondantes

Also Published As

Publication number Publication date
EP1313487A4 (fr) 2006-01-11
US20030040493A1 (en) 2003-02-27
CA2410886A1 (fr) 2001-12-06
EP1313487A1 (fr) 2003-05-28
US6664241B2 (en) 2003-12-16
WO2001091758A1 (fr) 2001-12-06
US20040138437A1 (en) 2004-07-15
JP2003534382A (ja) 2003-11-18

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application