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AU2001274827A1 - Porphyrin-based neutron capture agents for cancer therapy - Google Patents

Porphyrin-based neutron capture agents for cancer therapy

Info

Publication number
AU2001274827A1
AU2001274827A1 AU2001274827A AU7482701A AU2001274827A1 AU 2001274827 A1 AU2001274827 A1 AU 2001274827A1 AU 2001274827 A AU2001274827 A AU 2001274827A AU 7482701 A AU7482701 A AU 7482701A AU 2001274827 A1 AU2001274827 A1 AU 2001274827A1
Authority
AU
Australia
Prior art keywords
porphyrin
cancer therapy
neutron capture
capture agents
based neutron
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001274827A
Inventor
L. Jaquinod
S. J. Shetty
K. M. Smith
M. G. H. Vicente
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California
University of California Berkeley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California, University of California Berkeley filed Critical University of California
Publication of AU2001274827A1 publication Critical patent/AU2001274827A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001274827A 2000-05-09 2001-05-09 Porphyrin-based neutron capture agents for cancer therapy Abandoned AU2001274827A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20316000P 2000-05-09 2000-05-09
US60203160 2000-05-09
PCT/US2001/015433 WO2001085736A1 (en) 2000-05-09 2001-05-09 Porphyrin-based neutron capture agents for cancer therapy

Publications (1)

Publication Number Publication Date
AU2001274827A1 true AU2001274827A1 (en) 2001-11-20

Family

ID=22752759

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001274827A Abandoned AU2001274827A1 (en) 2000-05-09 2001-05-09 Porphyrin-based neutron capture agents for cancer therapy

Country Status (3)

Country Link
US (1) US7067653B2 (en)
AU (1) AU2001274827A1 (en)
WO (1) WO2001085736A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003094900A1 (en) * 2002-05-13 2003-11-20 Alexza Molecular Delivery Corporation Delivery of drug amines through an inhalation route
US7267990B2 (en) * 2002-11-15 2007-09-11 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Chelation of charged and uncharged molecules with porphyrin-based compounds
US6989443B2 (en) 2004-06-28 2006-01-24 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
WO2007050564A2 (en) 2005-10-25 2007-05-03 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Boron-containing porphyrin compounds and their uses
US9377569B2 (en) 2006-03-20 2016-06-28 High Performance Optics, Inc. Photochromic ophthalmic systems that selectively filter specific blue light wavelengths
US20120075577A1 (en) 2006-03-20 2012-03-29 Ishak Andrew W High performance selective light wavelength filtering providing improved contrast sensitivity
US8882267B2 (en) 2006-03-20 2014-11-11 High Performance Optics, Inc. High energy visible light filter systems with yellowness index values
US8287839B2 (en) 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8444953B2 (en) 2007-03-22 2013-05-21 Brookhaven Science Associates, Llc Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof
US20080279781A1 (en) * 2007-05-10 2008-11-13 Brookhaven Science Associates, Llc Glycosylated Carboranylporphyrins and Uses Thereof
RU2402554C2 (en) * 2008-07-17 2010-10-27 Российская Федерация, от имени которой выступает государственный заказчик-Федеральное агентство по науке и инновациям Carboranyl derivatives of flourinated porphyrins and metal complexes thereof, having photosensitiser properties, and synthesis method thereof
EP2793280B1 (en) * 2011-12-12 2017-03-29 Nippon Steel & Sumikin Chemical Co., Ltd. Organic electroluminescent element material and organic electroluminescent element using same
CN102993206B (en) * 2012-12-18 2015-07-22 聊城大学 Method for synthesising tetraphenylporphyrin metal complex via one-step process
US9798163B2 (en) 2013-05-05 2017-10-24 High Performance Optics, Inc. Selective wavelength filtering with reduced overall light transmission
RU2551539C2 (en) * 2013-08-01 2015-05-27 Федеральное Государственное Бюджетное Учреждение Науки Институт Биохимической Физики Им. Н.М. Эмануэля Российской Академии Наук (Ибхф Ран) Method of producing borated porphyrins
US9683102B2 (en) * 2014-05-05 2017-06-20 Frontier Scientific, Inc. Photo-stable and thermally-stable dye compounds for selective blue light filtered optic
RU2615770C1 (en) * 2015-12-21 2017-04-11 Общество с ограниченной ответственностью "Пермская химическая компания" Borated derivatives of fluorinated bacteriochlorines and their metal complexes with antitumor activity
WO2022019892A1 (en) * 2020-07-21 2022-01-27 Ankh Life Sciences Limited Therapeutic agents and uses thereof
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959356A (en) * 1989-05-26 1990-09-25 The United States Of America As Represented By The United States Department Of Energy Porphyrins for boron neutron capture therapy
US5877165A (en) * 1995-11-02 1999-03-02 Brookhaven Science Associates Boronated porhyrins and methods for their use

Also Published As

Publication number Publication date
WO2001085736A1 (en) 2001-11-15
US7067653B2 (en) 2006-06-27
US20040014737A1 (en) 2004-01-22

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