[go: up one dir, main page]

AU2001273559A1 - Methods of ligation mediated chimeragenesis utilizing populations of scaffold and donor nucleic acids - Google Patents

Methods of ligation mediated chimeragenesis utilizing populations of scaffold and donor nucleic acids

Info

Publication number
AU2001273559A1
AU2001273559A1 AU2001273559A AU7355901A AU2001273559A1 AU 2001273559 A1 AU2001273559 A1 AU 2001273559A1 AU 2001273559 A AU2001273559 A AU 2001273559A AU 7355901 A AU7355901 A AU 7355901A AU 2001273559 A1 AU2001273559 A1 AU 2001273559A1
Authority
AU
Australia
Prior art keywords
chimeragenesis
scaffold
populations
utilizing
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001273559A
Inventor
Joseph J. Arensdorf
Wayne M. Coco
Lance P. Encell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enchira Biotechnology Corp
Original Assignee
Enchira Biotechnology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enchira Biotechnology Corp filed Critical Enchira Biotechnology Corp
Publication of AU2001273559A1 publication Critical patent/AU2001273559A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1031—Mutagenizing nucleic acids mutagenesis by gene assembly, e.g. assembly by oligonucleotide extension PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2001273559A 2000-07-18 2001-07-18 Methods of ligation mediated chimeragenesis utilizing populations of scaffold and donor nucleic acids Abandoned AU2001273559A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US21908500P 2000-07-18 2000-07-18
US21892100P 2000-07-18 2000-07-18
US60/218,921 2000-07-18
US60/219,085 2000-07-18
US69187300A 2000-10-19 2000-10-19
US69273200A 2000-10-19 2000-10-19
US09/691,873 2000-10-19
US09/692,732 2000-10-19
PCT/US2001/022640 WO2002006469A2 (en) 2000-07-18 2001-07-18 Methods of ligation mediated chimeragenesis utilizing populations of scaffold and donor nucleic acids

Publications (1)

Publication Number Publication Date
AU2001273559A1 true AU2001273559A1 (en) 2002-01-30

Family

ID=27499132

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001273559A Abandoned AU2001273559A1 (en) 2000-07-18 2001-07-18 Methods of ligation mediated chimeragenesis utilizing populations of scaffold and donor nucleic acids

Country Status (2)

Country Link
AU (1) AU2001273559A1 (en)
WO (1) WO2002006469A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991922B2 (en) 1998-08-12 2006-01-31 Proteus S.A. Process for in vitro creation of recombinant polynucleotide sequences by oriented ligation
US6951719B1 (en) 1999-08-11 2005-10-04 Proteus S.A. Process for obtaining recombined nucleotide sequences in vitro, libraries of sequences and sequences thus obtained
US20030036641A1 (en) * 2001-01-31 2003-02-20 Padgett Hal S. Methods for homology-driven reassembly of nucleic acid sequences
US20040132101A1 (en) 2002-09-27 2004-07-08 Xencor Optimized Fc variants and methods for their generation
GB2388604B (en) * 2002-05-17 2005-01-26 Alligator Bioscience Ab A method for in vitro molecular evolution of protein function
EP2364996B1 (en) 2002-09-27 2016-11-09 Xencor Inc. Optimized FC variants and methods for their generation
US20040110213A1 (en) * 2002-09-30 2004-06-10 Eugeni Namsaraev Polynucleotide synthesis and labeling by kinetic sampling ligation
JP2007527206A (en) * 2003-04-04 2007-09-27 ユニバーシティ オブ ローザンヌ Peptabody for cancer treatment
US8883147B2 (en) 2004-10-21 2014-11-11 Xencor, Inc. Immunoglobulins insertions, deletions, and substitutions
US8399618B2 (en) 2004-10-21 2013-03-19 Xencor, Inc. Immunoglobulin insertions, deletions, and substitutions
WO2005056759A2 (en) 2003-12-04 2005-06-23 Xencor, Inc. Methods of generating variant proteins with increased host string content and compositions thereof
WO2005092925A2 (en) 2004-03-24 2005-10-06 Xencor, Inc. Immunoglobulin variants outside the fc region
CA2587617C (en) 2004-11-12 2011-02-01 Xencor, Inc. Fc variants with altered binding to fcrn
CA2594356C (en) 2005-01-05 2018-07-17 F-Star Biotechnologische Forschungs- Und Entwicklungsges.M.B.H. Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
GB0500703D0 (en) * 2005-01-14 2005-02-23 Bioinvent Int Ab Molecular biology method
AT503889B1 (en) 2006-07-05 2011-12-15 Star Biotechnologische Forschungs Und Entwicklungsges M B H F MULTIVALENT IMMUNE LOBULINE
ES2975748T3 (en) 2007-06-26 2024-07-12 F Star Therapeutics Ltd Presentation of bonding agents
US7682809B2 (en) 2008-01-11 2010-03-23 Agilent Technologies, Inc. Direct ATP release sequencing
EP2113255A1 (en) 2008-05-02 2009-11-04 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Cytotoxic immunoglobulin
CN108603190B (en) 2015-09-08 2023-05-23 美国冷泉港实验室 Determination of gene copy number using high throughput multiple sequencing of fragmented nucleotides

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5518900A (en) * 1993-01-15 1996-05-21 Molecular Tool, Inc. Method for generating single-stranded DNA molecules
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6335160B1 (en) * 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US5965408A (en) * 1996-07-09 1999-10-12 Diversa Corporation Method of DNA reassembly by interrupting synthesis
US6153410A (en) * 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
FR2782323B1 (en) * 1998-08-12 2002-01-11 Proteus PROCESS FOR THE IN VITRO PRODUCTION OF RECOMBINANT POLYNUCLEOTIDE SEQUENCES, SEQUENCE BANKS AND SEQUENCES THUS OBTAINED
IL138002A0 (en) * 1999-01-19 2001-10-31 Maxygen Inc Methods for making character strings, polynucleotides and polypeptides having desired characteristics
AU1098001A (en) * 1999-10-19 2001-04-30 Enchira Biotechnology Corporation Method for directed evolution by random chimeragenesis on transient templates
WO2001029212A1 (en) * 1999-10-19 2001-04-26 Enchira Biotechnology Corporation Methods for chimeragenesis of whole genomes or large polynucleotides

Also Published As

Publication number Publication date
WO2002006469A3 (en) 2002-08-15
WO2002006469A2 (en) 2002-01-24

Similar Documents

Publication Publication Date Title
AU2001273559A1 (en) Methods of ligation mediated chimeragenesis utilizing populations of scaffold and donor nucleic acids
AUPQ801700A0 (en) Enzyme and viral activation
AU2001283916A1 (en) Method and nucleic acids for the analysis of astrocytomas
AU3760100A (en) Immunostimulatory nucleic acids and antigens
AU2002252183A1 (en) Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases
AU7097400A (en) Platelet membrane glycoprotein vi (gpvi) dna and protein sequences, and uses thereof
AU2002366947A1 (en) Methods for quantitating nucleic acids using coupled ligation and amplification
AU3886599A (en) Silicone adhesives, articles, and methods
AU4341502A (en) Nod2 nucleic acids and proteins
AU2001241674A1 (en) Variant galactose oxidase, nucleic acid encoding same, and methods of using same
AU2001269039A1 (en) Immobilized nucleic acids and uses thereof
AU6611500A (en) Single-phase amplification of nucleic acids
AU2001294833A1 (en) Chlamydia pmp proteins, gene sequences and uses thereof
AU2735002A (en) Nod2 nucleic acids and proteins
AU2002258525A1 (en) Telomerase expression repressor proteins and methods of using the same
AU2001239953A1 (en) Methods of modulating cell-adhesion mediated drug resistance
AU2001274566A1 (en) Novel protein and dna thereof
AU2000239273A1 (en) Systems and methods of viral marketing
AU1855001A (en) A new member of the pak protein family, nucleic acids and methods related to thesame
AU2002359136A1 (en) Post-synthesis labeling of nucleic acids and uses thereof
AU2001268053A1 (en) Human sparc-homologous (hsparc-h1) gene and methods and uses thereof
AU2002367841A1 (en) Bsnd nucleic acids and proteins
AU2405300A (en) Uses of flavivirus rna-dependent rna polymerases
AU5634400A (en) Shank proteins and methods of use thereof
AU4312201A (en) Isolation and purification of nucleic acids