[go: up one dir, main page]

AU2001273453A1 - Nucleic acid hairpin probes and uses thereof - Google Patents

Nucleic acid hairpin probes and uses thereof

Info

Publication number
AU2001273453A1
AU2001273453A1 AU2001273453A AU7345301A AU2001273453A1 AU 2001273453 A1 AU2001273453 A1 AU 2001273453A1 AU 2001273453 A AU2001273453 A AU 2001273453A AU 7345301 A AU7345301 A AU 7345301A AU 2001273453 A1 AU2001273453 A1 AU 2001273453A1
Authority
AU
Australia
Prior art keywords
nucleic acid
hairpin probes
acid hairpin
probes
nucleic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001273453A
Inventor
Nanibhushan Dattagupta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Gene Technologies Inc
Original Assignee
Applied Gene Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/616,761 external-priority patent/US6380377B1/en
Application filed by Applied Gene Technologies Inc filed Critical Applied Gene Technologies Inc
Publication of AU2001273453A1 publication Critical patent/AU2001273453A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2001273453A 2000-07-14 2001-07-12 Nucleic acid hairpin probes and uses thereof Abandoned AU2001273453A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/616,761 2000-07-14
US09/616,761 US6380377B1 (en) 2000-07-14 2000-07-14 Nucleic acid hairpin probes and uses thereof
US09/823,647 US6596490B2 (en) 2000-07-14 2001-03-30 Nucleic acid hairpin probes and uses thereof
US09/823,647 2001-03-30
PCT/US2001/022166 WO2002006531A2 (en) 2000-07-14 2001-07-12 Nucleic acid hairpin probes and uses thereof

Publications (1)

Publication Number Publication Date
AU2001273453A1 true AU2001273453A1 (en) 2002-01-30

Family

ID=27087855

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001273453A Abandoned AU2001273453A1 (en) 2000-07-14 2001-07-12 Nucleic acid hairpin probes and uses thereof

Country Status (3)

Country Link
US (2) US6596490B2 (en)
AU (1) AU2001273453A1 (en)
WO (1) WO2002006531A2 (en)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7354390B1 (en) * 1996-09-30 2008-04-08 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Seed coat specific nucleotide sequence encoding peroxidase
US6825337B2 (en) * 2002-05-31 2004-11-30 Isis Pharmaceuticals, Inc. Antisense modulation of PLML expression
JP2003519495A (en) * 2000-01-11 2003-06-24 マキシジェン, インコーポレイテッド Integrated systems and methods for diversity generation and screening
US7846733B2 (en) 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
EP1427847B1 (en) 2000-12-13 2010-07-28 Nugen Technologies, Inc. Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
WO2002072773A2 (en) * 2001-03-09 2002-09-19 Nugen Technologies, Inc. Methods and compositions for amplification of rna sequences
ATE361996T1 (en) * 2001-03-09 2007-06-15 Nugen Technologies Inc METHODS AND COMPOSITIONS FOR DUPLICATION OF RNA SEQUENCES
JP2003043037A (en) * 2001-07-27 2003-02-13 Inst Of Physical & Chemical Res Hybridization substrate, method of manufacturing and using this substrate
US7094537B2 (en) * 2002-04-30 2006-08-22 Agilent Technologies, Inc. Micro arrays with structured and unstructured probes
AU2003256857A1 (en) * 2002-08-08 2004-02-25 Dharmacon, Inc. Short interfering rnas having a hairpin structure containing a non-nucleotide loop
AU2003295085A1 (en) * 2002-12-02 2004-06-23 Solexa Limited Recovery of original template
US20060094016A1 (en) * 2002-12-02 2006-05-04 Niall Gormley Determination of methylation of nucleic acid sequences
EP1594975A4 (en) 2002-12-04 2006-08-02 Applera Corp Multiplex amplification of polynucleotides
FR2852317B1 (en) * 2003-03-13 2006-08-04 PROBE BIOPUCES AND METHODS OF USE
CA2521084A1 (en) 2003-04-14 2004-10-28 Nugen Technologies, Inc. Global amplification using a randomly primed composite primer
EP1660679B1 (en) * 2003-08-01 2012-11-14 Dynal Biotech Inc. Self-hybridizing multiple target nucleic acid probes and methods of use
US7570443B2 (en) 2003-09-19 2009-08-04 Applied Biosystems, Llc Optical camera alignment
JP4942484B2 (en) * 2003-10-28 2012-05-30 エポック・バイオサイエンシーズ・インコーポレイテッド Fluorescent probe for DNA detection by hybridization with improved sensitivity and low background
WO2005077125A2 (en) * 2004-02-11 2005-08-25 Applera Corporation Methods and compositions for detecting nucleic acids
WO2005085475A1 (en) 2004-03-01 2005-09-15 Applera Corporation Methods, compositions and kits for use in polynucleotide amplification
US7593483B2 (en) * 2004-05-07 2009-09-22 Broadcom Corporation Nonlinear mapping in digital-to-analog and analog-to-digital converters
EP2290072B1 (en) 2004-05-28 2014-12-17 Asuragen, Inc. Methods and compositions involving microRNA
US8034554B2 (en) 2004-07-01 2011-10-11 Gen-Probe Incorporated Methods and compositions to detect nucleic acids in a biological sample
KR100663992B1 (en) 2004-07-05 2007-01-02 (주)바이오메드랩 Highly specific probe selection method and genotype probe for analyzing genotype of human papillomavirus
ATE494392T1 (en) 2004-09-21 2011-01-15 Life Technologies Corp TWO-COLOR REAL-TIME/ENDPOINT QUANTIFICATION OF MICRO-RNAS (MIRNAS)
AU2005333165B2 (en) 2004-11-12 2012-07-19 Asuragen, Inc. Methods and compositions involving miRNA and miRNA inhibitor molecules
WO2006081222A2 (en) 2005-01-25 2006-08-03 Compass Genetics, Llc. Isothermal dna amplification
US7939258B2 (en) 2005-09-07 2011-05-10 Nugen Technologies, Inc. Nucleic acid amplification procedure using RNA and DNA composite primers
US7368265B2 (en) * 2006-01-23 2008-05-06 Compass Genetics, Llc Selective genome amplification
CN101558167A (en) 2006-08-01 2009-10-14 应用生物系统有限公司 Detection of analytes and nucleic acids
US20080131878A1 (en) * 2006-12-05 2008-06-05 Asuragen, Inc. Compositions and Methods for the Detection of Small RNA
CA2671194A1 (en) * 2006-12-08 2008-06-19 Asuragen, Inc. Mir-20 regulated genes and pathways as targets for therapeutic intervention
WO2008096146A1 (en) 2007-02-07 2008-08-14 Solexa Limited Preparation of templates for methylation analysis
US20080274458A1 (en) * 2007-05-01 2008-11-06 Latham Gary J Nucleic acid quantitation methods
WO2009035554A2 (en) * 2007-09-07 2009-03-19 University Of Florida Research Foundation, Inc. Superior structure stability and selectivity of hairpin nucleic acid probes with an l-dna stem
WO2009036332A1 (en) 2007-09-14 2009-03-19 Asuragen, Inc. Micrornas differentially expressed in cervical cancer and uses thereof
WO2009067664A1 (en) * 2007-11-21 2009-05-28 The Govt. Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health And Human Services. Photoinduced electron transfer (pet) primer for nucleic acid amplification
US8071562B2 (en) 2007-12-01 2011-12-06 Mirna Therapeutics, Inc. MiR-124 regulated genes and pathways as targets for therapeutic intervention
US20090203531A1 (en) 2008-02-12 2009-08-13 Nurith Kurn Method for Archiving and Clonal Expansion
US7846666B2 (en) 2008-03-21 2010-12-07 Nugen Technologies, Inc. Methods of RNA amplification in the presence of DNA
WO2009126726A1 (en) * 2008-04-08 2009-10-15 Asuragen, Inc Methods and compositions for diagnosing and modulating human papillomavirus (hpv)
US8911948B2 (en) * 2008-04-30 2014-12-16 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
US9434988B2 (en) 2008-04-30 2016-09-06 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
EP2644709B1 (en) 2008-04-30 2014-12-17 Integrated Dna Technologies, Inc. RNase-H-based assays utilizing modified RNA monomers
EP2990487A1 (en) 2008-05-08 2016-03-02 Asuragen, INC. Compositions and methods related to mirna modulation of neovascularization or angiogenesis
US10316352B2 (en) 2008-05-13 2019-06-11 Gen-Probe Incorporated Methods of capturing a target nucleic acid for amplification and detection using an inactivatable target capture oligomer
CA2744004A1 (en) 2008-11-25 2010-06-17 Gen-Probe Incorporated Compositions and methods for detecting small rnas, and uses thereof
JP2012511927A (en) * 2008-12-17 2012-05-31 ライフ テクノロジーズ コーポレーション Methods, compositions, and kits for detecting allelic variants
EP2411543B1 (en) 2009-03-27 2017-04-19 Life Technologies Corporation Methods, compositions, and kits for detecting allelic variants
WO2010135692A2 (en) 2009-05-22 2010-11-25 Asuragen, Inc. Mirna biomarkers of prostate disease
US10208335B2 (en) 2009-08-05 2019-02-19 Life Technologies Corporation Methods for the analysis of proximity binding assay data
EP2470897A4 (en) 2009-08-28 2013-05-29 Asuragen Inc Mirna biomarkers of lung disease
WO2011130184A2 (en) 2010-04-11 2011-10-20 Life Technologies Corporation SYSTEMS AND METHODS FOR MODEL-BASED qPCR
EP3150723B1 (en) 2010-06-21 2019-01-30 Life Technologies Corporation Compositions, kits, and methods for synthesis and/or detection of nucleic acids
US9005895B2 (en) 2010-06-21 2015-04-14 Life Technologies Corporation Compositions, methods and kits for nucleic acid synthesis and amplification
US20130304390A1 (en) 2010-11-16 2013-11-14 Life Technologies Corporation Systems and Methods for the Analysis of Proximity Binding Assay Data
EP2913408A1 (en) 2010-12-29 2015-09-02 Life Technologies Corporation Ddao compounds as fluorescent reference standards
US20120196294A1 (en) 2011-01-17 2012-08-02 Life Technologies Corporation Workflow for detection of ligands using nucleic acids
WO2012142003A2 (en) 2011-04-15 2012-10-18 Life Technologies Corporation Chemical ligation
ES2955849T3 (en) 2011-06-08 2023-12-07 Life Technologies Corp Design and development of novel detergents for use in PCR systems
WO2012170907A2 (en) 2011-06-08 2012-12-13 Life Technologies Corporation Polymerization of nucleic acids using proteins having low isoelectric points
JP6154809B2 (en) 2011-06-27 2017-06-28 エーザイ・アール・アンド・ディー・マネジメント株式会社 MicroRNA biomarkers indicating Alzheimer's disease
CN103906848B (en) 2011-08-18 2016-03-02 雀巢产品技术援助有限公司 Compositions and methods for detecting allelic variants
US9644241B2 (en) 2011-09-13 2017-05-09 Interpace Diagnostics, Llc Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease
US20130179086A1 (en) 2011-11-29 2013-07-11 Life Technologies Corporation Systems and methods for the determination of a copy number of a genomic sequence
CN102643910B (en) * 2012-04-10 2014-10-15 中国人民解放军第三军医大学第一附属医院 Application of asymmetric multicolor fluorescence hairpin probe chain reaction in pathogenic bacterium detection
WO2013153911A1 (en) * 2012-04-12 2013-10-17 国立大学法人東京大学 Nucleic acid quantification method, detection probe, detection probe set, and nucleic acid detection method
KR20230074845A (en) 2012-06-14 2023-05-31 라이프 테크놀로지스 코포레이션 Novel compositions, methods and kits for polymerase chain reaction (pcr)
GB201217770D0 (en) 2012-10-04 2012-11-14 Base4 Innovation Ltd Biological probes and the use thereof
DK2914741T3 (en) 2012-11-02 2017-11-20 Life Technologies Corp New Compositions and Methods for Improving PCR Specificity
US11254977B2 (en) 2013-03-12 2022-02-22 Life Technologies Corporation Universal reporter-based genotyping methods and materials
JP2016515380A (en) 2013-03-15 2016-05-30 ライフ テクノロジーズ コーポレーション Lung cancer classification and feasibility index
US20150080239A1 (en) 2013-09-13 2015-03-19 Life Technologies Corporation Classification and Actionability Indices for Cancer
US9777333B2 (en) 2013-04-05 2017-10-03 Life Technologies Corporation Gene fusion
WO2015061714A1 (en) 2013-10-25 2015-04-30 Life Technologies Corporation Novel compounds for use in pcr systems and applications thereof
BR112016015595A2 (en) 2014-01-05 2017-10-24 Biomirna Holdings Ltd lung cancer determination methods
WO2015120382A1 (en) 2014-02-07 2015-08-13 The Johns Hopkins University Predicting response to epigenetic drug therapy
EP3438288A1 (en) 2014-03-27 2019-02-06 Life Technologies Corporation Gene fusions and gene variants associated with cancer
US11421268B2 (en) 2014-08-19 2022-08-23 Roche Molecular Systems, Inc. Methods and compositions for nucleic acid detection
US10876149B2 (en) 2014-10-22 2020-12-29 Prominex, Inc. Compositions and methods for the detection of nucleic acids
WO2016094330A2 (en) 2014-12-08 2016-06-16 20/20 Genesystems, Inc Methods and machine learning systems for predicting the liklihood or risk of having cancer
WO2016092045A1 (en) 2014-12-11 2016-06-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and kits for predicting medically refractory acute severe colitis
WO2016177774A1 (en) 2015-05-04 2016-11-10 Academisch Medisch Centrum Method of quantifying mirnas using normalization
US10196683B2 (en) * 2015-05-07 2019-02-05 Paris Sciences Et Lettres—Quartier Latin Formation of hairpins in situ using force-induced strand invasion
EP3440221B1 (en) 2016-04-06 2025-08-27 Life Technologies Corporation Methods for synthesis and detection of nucleic acids
WO2017189878A1 (en) * 2016-04-27 2017-11-02 Roka Bioscience, Inc. Compositions and methods for the detection of nucleic acids
EP3472349A1 (en) 2016-06-16 2019-04-24 Life Technologies Corporation Novel compositions, methods and kits for microorganism detection
AU2017295717B2 (en) 2016-07-15 2021-06-24 The Regents Of The University Of California Methods of producing nucleic acid libraries
CN118207299A (en) 2016-08-26 2024-06-18 生命技术公司 Nucleic acid extraction and amplification controls and methods of use thereof
WO2018045162A1 (en) 2016-09-01 2018-03-08 Biogen Ma Inc. Biomarkers predictive of primary progressive multiple sclerosis and uses thereof
US20200340041A1 (en) 2017-11-13 2020-10-29 Life Technologies Corporation Novel compositions, methods and kits for urinary tract microorganism detection
US11584929B2 (en) 2018-01-12 2023-02-21 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
JP7537748B2 (en) 2018-06-06 2024-08-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Methods for generating nucleic acid libraries and compositions and kits for carrying out the same - Patents.com
WO2020047081A1 (en) 2018-08-30 2020-03-05 Life Technologies Corporation Machine learning system for genotyping pcr assays
EP3844677A1 (en) 2018-08-31 2021-07-07 Life Technologies Corporation Image driven quality control for array based pcr
EP3719144A1 (en) 2019-04-05 2020-10-07 Fundación para la Investigación Biomédica del Hospital Universitario de la Paz (FIBHULP) Mir-151a-3p as an universal endogenous control for exosome cargo normalization
WO2021013592A1 (en) 2019-07-19 2021-01-28 Fundación Para La Investigación Biomédica Del Hospital Universitario La Paz (Fibhulp) Method for determining the response to treatment of a patient affected by non-small cell lung carcinoma (nsclc)
DE102020103966B4 (en) 2020-02-14 2022-03-03 Testo bioAnalytics GmbH Probe complex for the specific detection of at least one substance, corresponding method and use
DE102020103958B4 (en) 2020-02-14 2021-08-26 Testo bioAnalytics GmbH Oligonucleotide probe for the specific detection of microorganisms, corresponding method and use
US20230123603A1 (en) * 2020-03-03 2023-04-20 Universiteit Gent Hydrolysis-based probe and method for str genotyping
CN116323965A (en) 2020-07-23 2023-06-23 生命技术公司 Compositions, systems and methods for biological analysis using dyes
CN116075597A (en) 2020-07-23 2023-05-05 生命技术公司 Energy transfer dye conjugates for use in biological assays
US11649441B2 (en) 2020-10-07 2023-05-16 Abclonal Science, Inc. Taq DNA polymerase mutants for probe qPCR
US20240123054A1 (en) 2021-02-22 2024-04-18 Joseph COTROPIA Coronavirus antigens and epitopes and proteins that bind thereto
WO2022197882A1 (en) 2021-03-18 2022-09-22 Cotropia Joseph Human immunodeficiency virus (hiv) antigens and epitopes and proteins that bind thereto
EP4373891A2 (en) 2021-07-21 2024-05-29 Life Technologies Corporation Azaindole cyanine dyes, uses, and methods of preparation
CN117897454A (en) 2021-07-21 2024-04-16 生命技术公司 Dibenzoxanthene quencher, use and preparation method
CN117999035A (en) 2021-08-30 2024-05-07 高德美控股有限公司 Treatment of atopic dermatitis
WO2023039525A1 (en) 2021-09-10 2023-03-16 Life Technologies Corporation Master mix compositions, kits, and methods
WO2023081221A1 (en) 2021-11-02 2023-05-11 Life Technologies Corporation Compositions and methods for reducing master mix contamination
CN114410749B (en) * 2022-01-25 2023-10-24 河南中医药大学 Electrochemiluminescence detection kit and method based on click chemistry and ARGET-ATRP amplification strategy
WO2025007089A1 (en) 2023-06-30 2025-01-02 Life Technologies Corporation Compositions, methods and kits for nucleic acids synthesis and amplification
WO2025151807A1 (en) 2024-01-11 2025-07-17 Life Technologies Corporation Crude lysate sample extraction for digital pcr
WO2025175243A1 (en) 2024-02-15 2025-08-21 Life Technologies Corporation Amplification and data collection protocol for rapid genotyping
WO2025175212A1 (en) 2024-02-15 2025-08-21 Life Technologies Corporation Methods for rapid extraction-free genotyping
WO2025188713A1 (en) 2024-03-05 2025-09-12 Cotropia Joseph Feline leukemia virus antigens and epitopes and proteins that bind thereto

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4230797A (en) 1975-04-28 1980-10-28 Miles Laboratories, Inc. Heterogenous specific binding assay employing a coenzyme as label
IN142734B (en) 1975-04-28 1977-08-20 Miles Lab
US4134792A (en) 1976-12-06 1979-01-16 Miles Laboratories, Inc. Specific binding assay with an enzyme modulator as a labeling substance
US4238565A (en) 1978-06-22 1980-12-09 Miles Laboratories, Inc. Specific binding assay with a prosthetic group as a label component
US4948882A (en) 1983-02-22 1990-08-14 Syngene, Inc. Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
US5348855A (en) 1986-03-05 1994-09-20 Miles Inc. Assay for nucleic acid sequences in an unpurified sample
DE3803275A1 (en) 1988-02-04 1989-08-17 Dornier Medizintechnik PIEZOELECTRIC SHOCK WAVE SOURCE
US5118801A (en) 1988-09-30 1992-06-02 The Public Health Research Institute Nucleic acid process containing improved molecular switch
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
DE3924454A1 (en) 1989-07-24 1991-02-07 Cornelis P Prof Dr Hollenberg THE APPLICATION OF DNA AND DNA TECHNOLOGY FOR THE CONSTRUCTION OF NETWORKS FOR USE IN CHIP CONSTRUCTION AND CHIP PRODUCTION (DNA CHIPS)
US5149797A (en) 1990-02-15 1992-09-22 The Worcester Foundation For Experimental Biology Method of site-specific alteration of rna and production of encoded polypeptides
GB9027211D0 (en) 1990-12-14 1991-02-06 Smithkline Beecham Plc Medicaments
US5587472A (en) 1991-08-13 1996-12-24 Bayer Corporation Coumarin-labeled nucleoside 5'-triphosphates
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
EP1086742B2 (en) 1991-11-22 2007-03-14 Affymetrix, Inc. (a Delaware Corporation) Combinatorial strategies for polymer synthesis
US5312233A (en) 1992-02-25 1994-05-17 Ivek Corporation Linear liquid dispensing pump for dispensing liquid in nanoliter volumes
US5541061A (en) 1992-04-29 1996-07-30 Affymax Technologies N.V. Methods for screening factorial chemical libraries
JPH0622798A (en) 1992-07-07 1994-02-01 Hitachi Ltd Method for determining base sequence
DE4222254A1 (en) 1992-07-07 1994-01-13 Bayer Ag Photochemical labeling of nucleic acids with digoxigenin reagents and their use in gene probe test systems
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
EP0601889A2 (en) 1992-12-10 1994-06-15 Maine Medical Center Research Institute Nucleic acid probes
US5861242A (en) 1993-06-25 1999-01-19 Affymetrix, Inc. Array of nucleic acid probes on biological chips for diagnosis of HIV and methods of using the same
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US5932450A (en) 1995-06-07 1999-08-03 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using digestible templates
AU2804597A (en) 1996-04-15 1997-11-07 University Of Alberta Synthesis of fluorophore-labeled dna
US5866336A (en) 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
JP3891620B2 (en) 1996-11-14 2007-03-14 株式会社アイシン・コスモス研究所 Nucleic acid probe molecule having a hairpin structure, and nucleic acid detection method using the nucleic acid probe molecule
DE19716073A1 (en) 1997-04-17 1998-10-22 Boehringer Mannheim Gmbh Dosing device for dispensing small amounts of liquid
ATE478090T1 (en) 1997-10-27 2010-09-15 Boston Probes Inc METHODS, TEST SETS AND COMPOSITIONS RELATED TO ßPNA MOLECULAR BEACONSß
CA2343067A1 (en) 1998-09-21 2000-03-30 Ribozyme Pharmaceuticals, Inc. Hairpin hybridizer molecules for modulation of gene expression
US6277607B1 (en) 1999-05-24 2001-08-21 Sanjay Tyagi High specificity primers, amplification methods and kits

Also Published As

Publication number Publication date
WO2002006531A2 (en) 2002-01-24
US20020142309A1 (en) 2002-10-03
US20030165963A1 (en) 2003-09-04
WO2002006531A3 (en) 2003-07-10
US6596490B2 (en) 2003-07-22

Similar Documents

Publication Publication Date Title
AU2001273453A1 (en) Nucleic acid hairpin probes and uses thereof
AU2002239284A1 (en) Methods and devices for characterizing duplex nucleic acid molecules
AU2002332679A1 (en) Targeted nucleic acid constructs and uses related thereto
AU5091201A (en) Vegf-modulated genes and methods employing them
AU4341502A (en) Nod2 nucleic acids and proteins
AU2001271669A1 (en) Multipartite high-affinity nucleic acid probes
AU2002245184A1 (en) Nucleic acid amplification
AU2001293583A1 (en) Antisense iap nucleic acids and uses thereof
AU2001293336A1 (en) Nucleic acid detection medium
AU2001234455A1 (en) Informative nucleic acid arrays and methods for making same
AU2001288393A1 (en) Probes and decoder oligonucleotides
GB0002814D0 (en) Nucleic acids and their uses
AU2001269039A1 (en) Immobilized nucleic acids and uses thereof
IL134580A0 (en) Nucleic acid sequences and different uses thereof
AU2001278655A1 (en) Novel nucleic acid and amino acid sequences
AU2735002A (en) Nod2 nucleic acids and proteins
AU2001274566A1 (en) Novel protein and dna thereof
AU2001270478A1 (en) Gene expression in biological conditions
IL149679A0 (en) Nucleic acid construct and methods utilizing the same
AU2001249929A1 (en) Fdrg proteins and nucleic acid molecules and uses therefor
EP1409683A4 (en) i HELICOBACTER /i PROTEINS, NUCLEIC ACIDS AND USES THEREOF
AU2001292922A1 (en) Nucleic acid detection
GB0021008D0 (en) Protein and nucleic acid sequence
AU2001268053A1 (en) Human sparc-homologous (hsparc-h1) gene and methods and uses thereof
GB0020952D0 (en) Genes and proteins and their uses