[go: up one dir, main page]

AU2001273350A1 - Transgenic mice containing targeted kinase gene disruptions - Google Patents

Transgenic mice containing targeted kinase gene disruptions

Info

Publication number
AU2001273350A1
AU2001273350A1 AU2001273350A AU7335001A AU2001273350A1 AU 2001273350 A1 AU2001273350 A1 AU 2001273350A1 AU 2001273350 A AU2001273350 A AU 2001273350A AU 7335001 A AU7335001 A AU 7335001A AU 2001273350 A1 AU2001273350 A1 AU 2001273350A1
Authority
AU
Australia
Prior art keywords
transgenic mice
kinase gene
mice containing
gene disruptions
targeted kinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001273350A
Inventor
Keith D. Allen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deltagen Inc
Original Assignee
Deltagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deltagen Inc filed Critical Deltagen Inc
Publication of AU2001273350A1 publication Critical patent/AU2001273350A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276Knock-out vertebrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/072Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/20Animal model comprising regulated expression system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0393Animal model comprising a reporter system for screening tests
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/30Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Environmental Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001273350A 2000-07-11 2001-07-10 Transgenic mice containing targeted kinase gene disruptions Abandoned AU2001273350A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US21733000P 2000-07-11 2000-07-11
US21735400P 2000-07-11 2000-07-11
US60/217,354 2000-07-11
US60/217,330 2000-07-11
US22166600P 2000-07-27 2000-07-27
US60/221,666 2000-07-27
US22282100P 2000-08-04 2000-08-04
US60/222,821 2000-08-04
PCT/US2001/021821 WO2002003790A2 (en) 2000-07-11 2001-07-10 Transgenic mice containing targeted kinase gene disruptions

Publications (1)

Publication Number Publication Date
AU2001273350A1 true AU2001273350A1 (en) 2002-01-21

Family

ID=27499068

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001273350A Abandoned AU2001273350A1 (en) 2000-07-11 2001-07-10 Transgenic mice containing targeted kinase gene disruptions

Country Status (2)

Country Link
AU (1) AU2001273350A1 (en)
WO (1) WO2002003790A2 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5919997A (en) * 1993-11-18 1999-07-06 Cold Spring Habor Labortary Transgenic mice having modified cell-cycle regulation
WO1999066051A2 (en) * 1998-06-16 1999-12-23 Sugen, Inc. Nek-related and bub1-related protein kinases

Also Published As

Publication number Publication date
WO2002003790A3 (en) 2003-09-25
WO2002003790A2 (en) 2002-01-17

Similar Documents

Publication Publication Date Title
AU2002303184A1 (en) Transgenic mice containing gpcr5-1 gene disruptions
AU2002255979A1 (en) Transgenic mice containing beta3galt2 gene disruptions
AU2002239538A1 (en) Transgenic mice containing glucagon receptor gene disruptions
AU2002306982A1 (en) Transgenic mice containing msk2 serine/threonine kinase gene disruptions
AU2002306969A1 (en) Transgenic mice containing mglur7 metabotropic glutamate receptor gene disruptions
AU2002230737A1 (en) Transgenic mice containing huntingtin interacting protein 1 gene disruptions
AU2001282894A1 (en) Transgenic mice containing targeted gene disruptions
IL151759A0 (en) Transgenic mice containing targeted gene disruptions
AU2002226089A1 (en) Transgenic mice containing glutamate receptor (grik5) gene disruptions
AU2002239540A1 (en) Transgenic mice containing channel protein target gene disruptions
ZA200203820B (en) Transgenic mice containing TRP gene disruptions.
AU2001271902A1 (en) Transgenic mice containing targeted gpcr gene disruptions
AU2002217989A1 (en) Transgenic mice containing targeted gene disruptions
AU2002239539A1 (en) Transgenic mice containing targeted gene disruptions
AU2001273383A1 (en) Transgenic mice containing targeted gene disruptions
AU2002228798A1 (en) Transgenic mice containing perk protein kinase gene disruptions
AU2001271880A1 (en) Transgenic mice containing targeted phosphatase gene disruptions
AU2001273350A1 (en) Transgenic mice containing targeted kinase gene disruptions
AU2001271878A1 (en) Transgenic mice containing targeted gene disruptions
AU2002248179A1 (en) Transgenic mice containing gprc5b-like gene disruptions
AU2002226092A1 (en) Transgenic mice containing bsmap gene disruptions
AU2002228844A1 (en) Transgenic mice containing targeted gene disruptions
AU2001273351A1 (en) Transgenic mice containing targeted gene disruptions
AU2001273233A1 (en) Transgenic mice containing cx2 gene disruptions
AU2002227220A1 (en) Transgenic mice containing polycystin-related gene disruptions