AU2001272452A1 - Preparation containing an oxygen carrier for regeneration of the skin in the case of oxygen deficiency - Google Patents
Preparation containing an oxygen carrier for regeneration of the skin in the case of oxygen deficiencyInfo
- Publication number
- AU2001272452A1 AU2001272452A1 AU2001272452A AU7245201A AU2001272452A1 AU 2001272452 A1 AU2001272452 A1 AU 2001272452A1 AU 2001272452 A AU2001272452 A AU 2001272452A AU 7245201 A AU7245201 A AU 7245201A AU 2001272452 A1 AU2001272452 A1 AU 2001272452A1
- Authority
- AU
- Australia
- Prior art keywords
- gel
- oxygen
- preparation
- regeneration
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000002360 preparation method Methods 0.000 title abstract 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052760 oxygen Inorganic materials 0.000 title abstract 2
- 239000001301 oxygen Substances 0.000 title abstract 2
- 206010021143 Hypoxia Diseases 0.000 title 1
- 230000008929 regeneration Effects 0.000 title 1
- 238000011069 regeneration method Methods 0.000 title 1
- 102000001554 Hemoglobins Human genes 0.000 abstract 4
- 108010054147 Hemoglobins Proteins 0.000 abstract 4
- 102000036675 Myoglobin Human genes 0.000 abstract 3
- 108010062374 Myoglobin Proteins 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 239000000499 gel Substances 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000000017 hydrogel Substances 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
Abstract
In an externally applied preparation (A) comprising oxygen carrier (I), where (I) is incorporated as a molecular dispersion in a preparation of gel-like consistency. An independent claim is included for the preparation of (A), by incorporating a gel-forming agent (specifically a hydrogel) in water, optionally incorporating additives, adding reactants (Specifically sodium hydroxide) to initiate gel formation and adding a solution containing hemoglobin (HG) and optionally myoglobin (MG) having a concentration of 150-450 g/l, such that the gel contains 0.1-20% HG or HG/MG. - ACTIVITY : Dermatological; vulnerary. No biological data given. - MECHANISM OF ACTION : None given.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10031741.3 | 2000-06-29 | ||
| DE10031741A DE10031741A1 (en) | 2000-06-29 | 2000-06-29 | Externally applied oxygen carrier preparation for treating oxygen deficiency states of the skin, comprises active agent, specifically hemoglobin or its mixture with myoglobin, incorporated in a gel carrier |
| PCT/EP2001/006328 WO2002000246A2 (en) | 2000-06-29 | 2001-06-02 | Preparation containing an oxygen carrier for regeneration of the skin in the case of oxygen deficiency |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001272452A1 true AU2001272452A1 (en) | 2002-01-08 |
Family
ID=7647245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001272452A Abandoned AU2001272452A1 (en) | 2000-06-29 | 2001-06-02 | Preparation containing an oxygen carrier for regeneration of the skin in the case of oxygen deficiency |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20030180365A1 (en) |
| EP (1) | EP1303297B1 (en) |
| AT (1) | ATE282427T1 (en) |
| AU (1) | AU2001272452A1 (en) |
| DE (2) | DE10031741A1 (en) |
| ES (1) | ES2232645T3 (en) |
| WO (1) | WO2002000246A2 (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10212321A1 (en) * | 2002-03-20 | 2003-10-09 | Sanguibio Tech Ag | Use of one or more natural or modified oxygen binders freed from plasma and cell wall components for the external treatment of open, in particular chronic wounds |
| DE10342449A1 (en) * | 2003-09-13 | 2005-04-07 | Beiersdorf Ag | Use of oxygen in cosmetic or dermatological preparations |
| WO2005062765A2 (en) * | 2003-12-18 | 2005-07-14 | Subq Llc | Implantable biosensor and methods of use thereof |
| DE10360503A1 (en) * | 2003-12-22 | 2005-07-14 | Sanguibiotech Gmbh | Combination set and method for the bio-regenerative treatment of skin |
| DE102004001266A1 (en) * | 2004-01-07 | 2005-08-18 | Beiersdorf Ag | Cosmetic and/or dermatological compositions especially for treating hair loss contain native, modified or recombinant proteinogenic oxygen carriers |
| FR2917292B1 (en) * | 2007-06-18 | 2014-06-13 | Centre Nat Rech Scient | USE OF A HEMOGLOBIN FOR THE PREPARATION OF DRESSINGS, AND DRESSINGS THUS PREPARED |
| US20130177641A1 (en) * | 2011-01-07 | 2013-07-11 | Vindico NanoBio Technology Inc. | Compositions and methods for delivery of high-affinity oxygen binding agents to tumors |
| EP2550973B1 (en) * | 2011-07-23 | 2013-08-28 | SastoMed GmbH | Wound spray |
| EP2614833A1 (en) * | 2012-01-13 | 2013-07-17 | SastoMed GmbH | Scarring reducing wound treatment |
| US10729748B2 (en) * | 2012-01-13 | 2020-08-04 | Mölnlycke Health Care Ab | Scarring reducing wound treatment |
| US10456452B2 (en) | 2015-07-02 | 2019-10-29 | Poseida Therapeutics, Inc. | Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles |
| JP2018535189A (en) | 2015-09-02 | 2018-11-29 | メトロノーム・ヘルス、インコーポレイテッド | System and method for continuous health monitoring using a photo-enzyme analyte sensor |
| US20190046547A1 (en) * | 2016-02-08 | 2019-02-14 | Hackensack University Medical Center | Compositions and methods for treating chronic wounds |
| US9977258B2 (en) * | 2016-04-14 | 2018-05-22 | Johnson & Johnson Vision Care, Inc. | Methods and apparatus to enhance oxygen concentrations for ophthalmic devices |
| US11213594B2 (en) | 2016-04-29 | 2022-01-04 | Poseida Therapeutics, Inc. | Poly(histidine)-based micelles for complexation and delivery of proteins and nucleic acids |
| EP3421044A1 (en) * | 2017-06-26 | 2019-01-02 | SastoMed GmbH | Oxygen carriers for the treatment of skin indispositions |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2527210A (en) * | 1944-01-25 | 1950-10-24 | John O Bower | Hemoglobin solution and method |
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4001401A (en) * | 1975-02-02 | 1977-01-04 | Alza Corporation | Blood substitute and blood plasma expander comprising polyhemoglobin |
| US4001200A (en) * | 1975-02-27 | 1977-01-04 | Alza Corporation | Novel polymerized, cross-linked, stromal-free hemoglobin |
| GB8710598D0 (en) * | 1987-05-05 | 1987-06-10 | Star Medical Diagnostics Ltd | Hemoglobin based blood substitute |
| FR2641463B1 (en) * | 1989-01-09 | 1991-03-08 | Sederma Sa | COSMETIC PREPARATIONS FOR OXYGENATION OF THE SKIN |
| US5386014A (en) * | 1989-11-22 | 1995-01-31 | Enzon, Inc. | Chemically modified hemoglobin as an effective, stable, non-immunogenic red blood cell substitute |
| US5312808A (en) * | 1989-11-22 | 1994-05-17 | Enzon, Inc. | Fractionation of polyalkylene oxide-conjugated hemoglobin solutions |
| US5439882A (en) * | 1989-12-29 | 1995-08-08 | Texas Tech University Health Sciences Center | Blood substitute |
| US5248785A (en) * | 1990-02-12 | 1993-09-28 | Virginia Commonwealth University | Using allosteric hemoglobin modifiers to decrease oxygen affinity in blood |
| FR2717385B1 (en) * | 1994-03-21 | 1996-04-19 | Oreal | Cosmetic composition containing in combination a superoxide dismutase and a porphyrin. |
| WO1997015313A1 (en) * | 1995-10-26 | 1997-05-01 | Baxter International Inc. | Therapeutic use of hemoglobin in promoting wound healing |
| FR2741266A1 (en) * | 1995-11-16 | 1997-05-23 | Chassignole Jean Bernard | Cosmetic and therapeutic compositions contg a haemocyanin |
| WO1998006438A2 (en) * | 1996-08-12 | 1998-02-19 | Medlogic Global Corporation | Composition for pharmaceutical applications |
| DE19701037A1 (en) * | 1997-01-15 | 1998-07-16 | Sanguibiotech Ag | Hemoglobins provided with protective ligands of the oxygen binding sites as artificial oxygen carriers for direct biological-medical use and processes for their production |
| US6818018B1 (en) * | 1998-08-14 | 2004-11-16 | Incept Llc | In situ polymerizable hydrogels |
| CN1602601B (en) * | 2001-10-12 | 2010-09-08 | Geo信托有限公司 | Method and computer system for processing and issuing digital certificates |
| US20060015716A1 (en) * | 2003-08-15 | 2006-01-19 | Imcentric, Inc. | Program product for maintaining certificate on client network devices1 |
-
2000
- 2000-06-29 DE DE10031741A patent/DE10031741A1/en not_active Withdrawn
-
2001
- 2001-06-02 AU AU2001272452A patent/AU2001272452A1/en not_active Abandoned
- 2001-06-02 US US10/312,509 patent/US20030180365A1/en not_active Abandoned
- 2001-06-02 AT AT01951556T patent/ATE282427T1/en not_active IP Right Cessation
- 2001-06-02 WO PCT/EP2001/006328 patent/WO2002000246A2/en not_active Ceased
- 2001-06-02 ES ES01951556T patent/ES2232645T3/en not_active Expired - Lifetime
- 2001-06-02 DE DE50104553T patent/DE50104553D1/en not_active Expired - Fee Related
- 2001-06-02 EP EP01951556A patent/EP1303297B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002000246A3 (en) | 2002-05-10 |
| ES2232645T3 (en) | 2005-06-01 |
| WO2002000246A8 (en) | 2002-12-12 |
| US20030180365A1 (en) | 2003-09-25 |
| WO2002000246A2 (en) | 2002-01-03 |
| EP1303297B1 (en) | 2004-11-17 |
| DE50104553D1 (en) | 2004-12-23 |
| ATE282427T1 (en) | 2004-12-15 |
| DE10031741A1 (en) | 2002-01-17 |
| EP1303297A2 (en) | 2003-04-23 |
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