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AU2001271786A1 - Interferon-like protein zcyto21 - Google Patents

Interferon-like protein zcyto21

Info

Publication number
AU2001271786A1
AU2001271786A1 AU2001271786A AU7178601A AU2001271786A1 AU 2001271786 A1 AU2001271786 A1 AU 2001271786A1 AU 2001271786 A AU2001271786 A AU 2001271786A AU 7178601 A AU7178601 A AU 7178601A AU 2001271786 A1 AU2001271786 A1 AU 2001271786A1
Authority
AU
Australia
Prior art keywords
amino acid
zcyto21
interferon
acid sequence
genetically engineered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001271786A
Inventor
Brian A. Fox
Teresa Gilbert
Francis J Grant
Betty A. Haldeman
Scott R. Presnell
Paul O Sheppard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26910034&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2001271786(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of AU2001271786A1 publication Critical patent/AU2001271786A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

There is provided a transgenic mouse that has been genetically engineered to express a Zcyto21 gene, and a knock-out mouse, which has been genetically engineered to exhibit a complete absence of Zcyto21 gene function; wherein said Zcyto21 gene encodes a polypeptide comprising an amino acid sequence that has at least 90% amino acid sequence identity to amino acid residues 20-200 of SEQ ID NO: 2.
AU2001271786A 2000-06-30 2001-06-29 Interferon-like protein zcyto21 Abandoned AU2001271786A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21544600P 2000-06-30 2000-06-30
US60/215,446 2000-06-30
US28542401P 2001-04-20 2001-04-20
US60/285,424 2001-04-20
PCT/US2001/021087 WO2002002627A2 (en) 2000-06-30 2001-06-29 Interferon-like protein zcyto21

Publications (1)

Publication Number Publication Date
AU2001271786A1 true AU2001271786A1 (en) 2002-01-14

Family

ID=26910034

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001271786A Abandoned AU2001271786A1 (en) 2000-06-30 2001-06-29 Interferon-like protein zcyto21

Country Status (13)

Country Link
US (18) US6927040B2 (en)
EP (4) EP1294888B1 (en)
JP (1) JP4377126B2 (en)
CN (1) CN100448993C (en)
AT (2) ATE404670T1 (en)
AU (1) AU2001271786A1 (en)
BR (1) BR0112119A (en)
CA (1) CA2413258C (en)
DE (2) DE60135393D1 (en)
DK (2) DK1717316T3 (en)
ES (2) ES2311253T3 (en)
RU (1) RU2292394C2 (en)
WO (1) WO2002002627A2 (en)

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WO2003029262A2 (en) * 2001-08-29 2003-04-10 Vanderbilt University The human mob-5 (il-24) receptors and uses thereof
US7820793B2 (en) 2002-02-08 2010-10-26 University Of Medicine And Dentistry Of New Jersey IFN-λ polypeptides and compositions
US20040029228A1 (en) 2002-04-19 2004-02-12 Presnell Scott R. Cytokine receptor
WO2004015113A2 (en) * 2002-08-07 2004-02-19 Delta Biotechnology Ltd. Albumin-fused ciliary neurotrophic factor
JP2006509041A (en) * 2002-10-23 2006-03-16 ザイモジェネティクス，インコーポレイティド Methods for treating viral infections using IL-28 and IL-29
DK1668031T3 (en) 2003-08-07 2008-06-30 Zymogenetics Inc Homogeneous Preparations of IL-29
EP1750749A2 (en) * 2004-04-02 2007-02-14 ZymoGenetics, Inc. Il-28 and il-29 cysteine mutants for treating viral infection
EP2389944A1 (en) 2004-07-29 2011-11-30 ZymoGenetics, L.L.C. Use of IL-28 and IL-29 to treat cancer
RU2389502C2 (en) * 2004-07-29 2010-05-20 Займодженетикс, Инк. Application of il-28 and il-29 for treatment carcinoma and autoimmune disorders
US20060178301A1 (en) * 2005-02-04 2006-08-10 Mathias Jurs Albumin-fused ciliary neurotrophic factor
US20070053933A1 (en) * 2005-07-20 2007-03-08 Sheppard Paul O IL28 and IL29 TRUNCATED CYSTEINE MUTANTS AND ANTIVIRAL METHODS OF USING SAME
WO2007013944A2 (en) 2005-07-20 2007-02-01 Zymogenetics, Inc. Use of truncated cysteine il28 and il29 mutants to treat cancers and autoimmune disorders
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RU2504552C2 (en) 2007-12-07 2014-01-20 Займодженетикс, Инк. Monoclonal antibodies against il-21 of human being
CN102016023A (en) 2008-04-04 2011-04-13 宾夕法尼亚州立大学托管会 Vaccines and immunotherapy using IL-28 and compositions and methods of use thereof
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FR2975185A1 (en) * 2011-05-12 2012-11-16 Univ Claude Bernard Lyon METHOD FOR IN VITRO DETERMINATION OF THE PRESENCE OF A MULTIPLE SCLEROSIS
RU2549710C2 (en) * 2012-06-29 2015-04-27 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Method for purifying recombinant protein of type iii interferon-like factor
CN102998450B (en) * 2012-11-22 2014-10-15 北京正旦国际科技有限责任公司 Immuno-mass spectrometric detection kit for esophagus cancer
CN109293782A (en) 2014-01-08 2019-02-01 德益阳光生物技术（北京）有限责任公司 Fused polypeptide and application method
US10076512B2 (en) 2014-05-01 2018-09-18 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
HUE054068T2 (en) 2015-04-21 2021-08-30 Eiger Biopharmaceuticals Inc Pharmaceutical compositions comprising lonafarnib and ritonavir
KR20180110127A (en) 2016-02-19 2018-10-08 아이거 바이오파마슈티컬스 인코포레이티드 Treatment of Delta Hepatitis Virus Infection with Interferon Lambda
EP3518958A4 (en) * 2016-09-30 2021-03-31 The Board of Trustees of the Leland Stanford Junior University TYPE III INTERFERONS AND VARIANT SYNTHEKINS

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Also Published As

Publication number Publication date
RU2292394C2 (en) 2007-01-27
US20110054148A1 (en) 2011-03-03
CA2413258A1 (en) 2002-01-10
US7253261B2 (en) 2007-08-07
US7445913B2 (en) 2008-11-04
DK1717316T3 (en) 2008-12-08
US20070042468A1 (en) 2007-02-22
CN1443240A (en) 2003-09-17
RU2003103099A (en) 2005-01-20
US20110172170A1 (en) 2011-07-14
WO2002002627A2 (en) 2002-01-10
EP2132984A3 (en) 2010-11-03
US20040146988A1 (en) 2004-07-29
US7485700B2 (en) 2009-02-03
US7919595B2 (en) 2011-04-05
EP1717316A1 (en) 2006-11-02
JP2004502419A (en) 2004-01-29
EP2132984A2 (en) 2009-12-16
US20090069274A1 (en) 2009-03-12
EP1939293A2 (en) 2008-07-02
US20050106682A1 (en) 2005-05-19
WO2002002627A3 (en) 2003-01-03
CN100448993C (en) 2009-01-07
US20100222266A1 (en) 2010-09-02
EP1939293A3 (en) 2008-07-09
US7833520B2 (en) 2010-11-16
ATE360696T1 (en) 2007-05-15
US7241870B2 (en) 2007-07-10
US20090326204A1 (en) 2009-12-31
ES2286128T3 (en) 2007-12-01
US20070043209A1 (en) 2007-02-22
EP1294888B1 (en) 2007-04-25
US20020039763A1 (en) 2002-04-04
DE60135393D1 (en) 2008-09-25
JP4377126B2 (en) 2009-12-02
US20120258458A1 (en) 2012-10-11
DE60128093T2 (en) 2007-12-27
US20070049736A1 (en) 2007-03-01
BR0112119A (en) 2003-05-06
ATE404670T1 (en) 2008-08-15
US20070048841A1 (en) 2007-03-01
US6927040B2 (en) 2005-08-09
ES2311253T3 (en) 2009-02-01
EP1294888A2 (en) 2003-03-26
US20080102490A1 (en) 2008-05-01
US7252969B2 (en) 2007-08-07
US7498154B2 (en) 2009-03-03
CA2413258C (en) 2012-01-03
DK1294888T3 (en) 2007-08-20
EP1717316B1 (en) 2008-08-13
US20080214788A1 (en) 2008-09-04
US7655223B2 (en) 2010-02-02
US20050014228A1 (en) 2005-01-20
US20050106680A1 (en) 2005-05-19
US20120036590A1 (en) 2012-02-09
DE60128093D1 (en) 2007-06-06

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