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AU2001270200A1 - Fatty acid synthase inhibitors - Google Patents

Fatty acid synthase inhibitors

Info

Publication number
AU2001270200A1
AU2001270200A1 AU2001270200A AU7020001A AU2001270200A1 AU 2001270200 A1 AU2001270200 A1 AU 2001270200A1 AU 2001270200 A AU2001270200 A AU 2001270200A AU 7020001 A AU7020001 A AU 7020001A AU 2001270200 A1 AU2001270200 A1 AU 2001270200A1
Authority
AU
Australia
Prior art keywords
fatty acid
acid synthase
synthase inhibitors
inhibitors
fatty
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001270200A
Inventor
Robert A Daines
Israil Pendrak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of AU2001270200A1 publication Critical patent/AU2001270200A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2001270200A 2000-06-27 2001-06-27 Fatty acid synthase inhibitors Abandoned AU2001270200A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21428000P 2000-06-27 2000-06-27
US60214280 2000-06-27
PCT/US2001/020458 WO2002000646A1 (en) 2000-06-27 2001-06-27 Fatty acid synthase inhibitors

Publications (1)

Publication Number Publication Date
AU2001270200A1 true AU2001270200A1 (en) 2002-01-08

Family

ID=22798484

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001270200A Abandoned AU2001270200A1 (en) 2000-06-27 2001-06-27 Fatty acid synthase inhibitors

Country Status (3)

Country Link
US (1) US6608059B1 (en)
AU (1) AU2001270200A1 (en)
WO (1) WO2002000646A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820682B2 (en) 2002-10-03 2010-10-26 Ono Pharmaceutical Co., Ltd. LPA receptor antagonist
AU2005311826A1 (en) * 2004-11-30 2006-06-08 Plexxikon, Inc. Indole derivatives for use as PPAR active compounds
WO2006090817A1 (en) * 2005-02-25 2006-08-31 Ono Pharmaceutical Co., Ltd. Indole compound and use thereof
EP1943245A2 (en) * 2005-09-07 2008-07-16 Plexxikon, Inc. 1,3-disubstituted indole derivatives for use as ppar modulators
CN101117328B (en) * 2006-08-01 2012-11-07 中国人民解放军军事医学科学院毒物药物研究所 Fatty acid synthetase inhibitor and application for treating bacterial infection
PE20090159A1 (en) * 2007-03-08 2009-02-21 Plexxikon Inc INDOL-PROPIONIC ACID DERIVED COMPOUNDS AS PPARs MODULATORS
AR072297A1 (en) 2008-06-27 2010-08-18 Novartis Ag DERIVATIVES OF INDOL-2-IL-PIRIDIN-3-ILO, PHARMACEUTICAL COMPOSITION THAT INCLUDES THEM AND ITS USE IN MEDICINES FOR THE TREATMENT OF DISEASES MEDIATED BY THE SYNTHESIS ALDOSTERONE.
TWI469965B (en) 2008-12-22 2015-01-21 Ono Pharmaceutical Co Ethynylindole compounds
WO2011066211A1 (en) * 2009-11-24 2011-06-03 Glaxosmithkline Llc Azabenzimidazoles as fatty acid synthase inhibitors
US8450350B2 (en) 2010-05-05 2013-05-28 Infinity Pharmaceuticals, Inc. Triazoles as inhibitors of fatty acid synthase
EP2566853B1 (en) 2010-05-05 2017-01-25 Infinity Pharmaceuticals, Inc. Tetrazolones as inhibitors of fatty acid synthase
MY162757A (en) 2010-06-21 2017-07-14 Ono Pharmaceutical Co New Crystalline Forms of 4,4’-[4-Fluoro-7-({4-[4-(3-Fluoro-2-Methylphenyl) Butoxy] Phenyl}Ethynyl)-2-Methyl-1H-Indole-1, 3-Diyl] Dibutanoic Acid
US20130196971A1 (en) * 2010-09-17 2013-08-01 Christopher Joseph Aquino Fatty acid synthase inhibitors
HUE045701T2 (en) 2013-03-13 2020-01-28 Forma Therapeutics Inc 2-Hydroxy-1- {4 - [(4-phenylphenyl) carbonyl] piperazin-1-yl} ethan-1-one derivatives and related compounds as fatty acid synthase (FASN) inhibitors for the treatment of cancer
WO2017165497A1 (en) 2016-03-22 2017-09-28 Leof Edward B Using fatty acid synthase inhibitors to treat fibrosis
TWI767148B (en) 2018-10-10 2022-06-11 美商弗瑪治療公司 Inhibiting fatty acid synthase (fasn)
WO2020092395A1 (en) 2018-10-29 2020-05-07 Forma Therapeutics, Inc. SOLID FORMS OF (4-(2-FLUORO-4-(1-METHYL-1 H-BENZO[d]IMIDAZOL-5-YL)BENZOYL) PIPERAZIN-1-YL)(1-HYDROXYCYCLOPROPYL)METHANONE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
FR2745003B1 (en) * 1996-02-16 1998-04-03 Adir NOVEL PSEUDOPEPTIDES DERIVED FROM NEUROKININS, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US6486211B1 (en) * 1999-10-22 2002-11-26 Smithkline Beecham Corporation Indole compounds

Also Published As

Publication number Publication date
WO2002000646A1 (en) 2002-01-03
US6608059B1 (en) 2003-08-19

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