AU2001270070A1 - Nitrosated and nitrosylated taxanes, compositions and methods of use - Google Patents
Nitrosated and nitrosylated taxanes, compositions and methods of useInfo
- Publication number
- AU2001270070A1 AU2001270070A1 AU2001270070A AU2001270070A AU2001270070A1 AU 2001270070 A1 AU2001270070 A1 AU 2001270070A1 AU 2001270070 A AU2001270070 A AU 2001270070A AU 2001270070 A AU2001270070 A AU 2001270070A AU 2001270070 A1 AU2001270070 A1 AU 2001270070A1
- Authority
- AU
- Australia
- Prior art keywords
- nitrosated
- compositions
- methods
- nitrosylated taxanes
- nitrosylated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940123237 Taxane Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21329400P | 2000-06-22 | 2000-06-22 | |
| US60/213,294 | 2000-06-22 | ||
| US22609000P | 2000-08-18 | 2000-08-18 | |
| US60/226,090 | 2000-08-18 | ||
| PCT/US2001/019939 WO2001098286A1 (en) | 2000-06-22 | 2001-06-22 | Nitrosated and nitrosylated taxanes, compositions and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2001270070A1 true AU2001270070A1 (en) | 2002-03-21 |
| AU2001270070B2 AU2001270070B2 (en) | 2006-03-16 |
Family
ID=26907932
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001270070A Ceased AU2001270070B2 (en) | 2000-06-22 | 2001-06-22 | Nitrosated and nitrosylated taxanes, compositions and methods of use |
| AU7007001A Pending AU7007001A (en) | 2000-06-22 | 2001-06-22 | Nitrosated and nitrosylated taxanes, compositions and methods of use |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU7007001A Pending AU7007001A (en) | 2000-06-22 | 2001-06-22 | Nitrosated and nitrosylated taxanes, compositions and methods of use |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6656966B2 (en) |
| EP (1) | EP1301500B1 (en) |
| JP (1) | JP2004501143A (en) |
| AU (2) | AU2001270070B2 (en) |
| CA (1) | CA2410632A1 (en) |
| DE (1) | DE60131537T2 (en) |
| WO (1) | WO2001098286A1 (en) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4850985B2 (en) * | 1993-07-29 | 2012-01-11 | アメリカ合衆国 | Method for treating atherosclerosis or restenosis using microtubule stabilizer |
| US20030040790A1 (en) | 1998-04-15 | 2003-02-27 | Furst Joseph G. | Stent coating |
| US8070796B2 (en) | 1998-07-27 | 2011-12-06 | Icon Interventional Systems, Inc. | Thrombosis inhibiting graft |
| US7967855B2 (en) | 1998-07-27 | 2011-06-28 | Icon Interventional Systems, Inc. | Coated medical device |
| US20050142217A1 (en) * | 2000-04-26 | 2005-06-30 | Adams Michael A. | Formulations and methods of using nitric oxide mimetics against a malignant cell phenotype |
| US7678391B2 (en) * | 2000-04-26 | 2010-03-16 | Queen's University At Kingston | Formulations and methods of using nitric oxide mimetics against a malignant cell phenotype |
| JP2003531179A (en) | 2000-04-26 | 2003-10-21 | クイーンズ ユニバーシティ アット キングストン | Formulations and methods of using nitric oxide mimetics for malignant cell phenotype |
| ATE343969T1 (en) † | 2000-09-29 | 2006-11-15 | Cordis Corp | COATED MEDICAL DEVICES |
| US20040110691A1 (en) * | 2001-11-13 | 2004-06-10 | Stamler Jonathan S. | Thiol reactive agents as a therapeutic modality |
| US6627602B2 (en) * | 2001-11-13 | 2003-09-30 | Duke University | Preventing desensitization of receptors |
| AU2006252204B2 (en) * | 2001-12-06 | 2010-07-08 | Duke University | Prevention of Flap Necrosis in Plastic Surgery |
| US20050064429A1 (en) * | 2002-03-07 | 2005-03-24 | Olivier Devuyst | Method for diagnosing and treating predisposition for accelerated autosomal dominant polycystic kidney disease |
| AU2003223491A1 (en) * | 2002-04-05 | 2003-10-27 | Nitromed, Inc. | Nitric oxide donors, compositions and methods of use |
| PT1496951E (en) | 2002-04-24 | 2006-10-31 | Insense Ltd | WOUND THINKS THAT UNDERSTAND AN OXIDORREDUCTASE ENZYME IN HYDRATED CONDITION |
| US20040038947A1 (en) | 2002-06-14 | 2004-02-26 | The Gov. Of The U.S. Of America As Represented By The Sec. Of The Dept. Of Health & Human Services | Method of treating ischemia/reperfusion injury with nitroxyl donors |
| US8016881B2 (en) | 2002-07-31 | 2011-09-13 | Icon Interventional Systems, Inc. | Sutures and surgical staples for anastamoses, wound closures, and surgical closures |
| US6936639B2 (en) * | 2002-08-21 | 2005-08-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nitroxyl progenitors in the treatment of heart failure |
| ES2377318T3 (en) | 2002-09-06 | 2012-03-26 | Cerulean Pharma Inc. | Cyclodextrin-based polymers for the delivery of covalently bound therapeutic agents to them |
| DK1608407T3 (en) * | 2003-03-20 | 2006-12-04 | Pharmacia Corp | Dispersible formulation of an anti-inflammatory agent |
| US20050004098A1 (en) * | 2003-03-20 | 2005-01-06 | Britten Nancy Jean | Dispersible formulation of an anti-inflammatory agent |
| US20040214753A1 (en) * | 2003-03-20 | 2004-10-28 | Britten Nancy Jean | Dispersible pharmaceutical composition for treatment of mastitis and otic disorders |
| US20050009931A1 (en) * | 2003-03-20 | 2005-01-13 | Britten Nancy Jean | Dispersible pharmaceutical composition for treatment of mastitis and otic disorders |
| ITMI20030743A1 (en) * | 2003-04-11 | 2004-10-12 | Biopeg Ltd | POLYETHYLENGLYCULATED DERIVATIVES THAT RELEASE NITRIC OXIDE. |
| US20050038498A1 (en) * | 2003-04-17 | 2005-02-17 | Nanosys, Inc. | Medical device applications of nanostructured surfaces |
| US7972616B2 (en) * | 2003-04-17 | 2011-07-05 | Nanosys, Inc. | Medical device applications of nanostructured surfaces |
| US7803574B2 (en) * | 2003-05-05 | 2010-09-28 | Nanosys, Inc. | Medical device applications of nanostructured surfaces |
| GB0313217D0 (en) | 2003-06-09 | 2003-07-16 | Insense Ltd | Improvements in or relating to skin dressings |
| WO2005023182A2 (en) * | 2003-08-28 | 2005-03-17 | Nitromed, Inc. | Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use |
| MXPA06007378A (en) * | 2003-12-23 | 2007-01-26 | Musc Found For Res Dev | Methods and compositions for the prevention and treatment of inflammatory diseases or conditions. |
| US7211108B2 (en) | 2004-01-23 | 2007-05-01 | Icon Medical Corp. | Vascular grafts with amphiphilic block copolymer coatings |
| US20050260557A1 (en) * | 2004-05-21 | 2005-11-24 | Mary Zacour | Method of quantifying the cell-binding properties of a medical device |
| CA2568640C (en) | 2004-06-04 | 2011-08-09 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical composition containing irbesartan |
| US20060039950A1 (en) * | 2004-08-23 | 2006-02-23 | Zhengrong Zhou | Multi-functional biocompatible coatings for intravascular devices |
| EP1789029A2 (en) * | 2004-08-30 | 2007-05-30 | Interstitial Therapeutics | Methods and compositions for the treatment of cell proliferation |
| US7540995B2 (en) | 2005-03-03 | 2009-06-02 | Icon Medical Corp. | Process for forming an improved metal alloy stent |
| US9107899B2 (en) | 2005-03-03 | 2015-08-18 | Icon Medical Corporation | Metal alloys for medical devices |
| WO2006110197A2 (en) | 2005-03-03 | 2006-10-19 | Icon Medical Corp. | Polymer biodegradable medical device |
| ES2986867T3 (en) | 2005-03-03 | 2024-11-12 | Mirus Llc | Enhanced metal alloys for medical devices |
| US20060222592A1 (en) * | 2005-04-05 | 2006-10-05 | Clemens Burda | Nanoparticles and methods of manufacturing nanoparticles for electronic and non-electronic applications |
| US20090298795A1 (en) * | 2005-06-23 | 2009-12-03 | The Johns Hopins University | Thiol-Sensitive Positive Inotropes |
| WO2007005758A2 (en) * | 2005-06-30 | 2007-01-11 | Mc3, Inc. | Methods , compositions and devices for promoting angiogenesis |
| EP1919357B1 (en) * | 2005-09-02 | 2013-03-27 | The Procter and Gamble Company | Methods for retail measurement of skin moisture content |
| US7566308B2 (en) * | 2005-10-13 | 2009-07-28 | Cardiac Pacemakers, Inc. | Method and apparatus for pulmonary artery pressure signal isolation |
| CN101869514B (en) * | 2005-11-16 | 2012-08-08 | 学校法人东海大学 | Controlled drug-release composition and drug-releasable medical device |
| US20080051702A1 (en) * | 2006-08-24 | 2008-02-28 | Herrmann Robert A | Therapeutic agent delivery for the treatment of asthma via implantable and insertable medical devices |
| US9339593B2 (en) * | 2007-01-11 | 2016-05-17 | Robert L. Bjork, JR. | Drug-eluting coronary artery stent coated with anti-platelet-derived growth factor antibodies overlaying extracellular matrix proteins with an outer coating of anti-inflammatory (calcineurin inhibitor) and/or anti-proliferatives |
| EP2101683A4 (en) * | 2007-01-11 | 2014-12-03 | Robert Lamar Bjork Jr | Multiple drug-eluting coronary artery stent for percutaneous coronary artery intervention |
| JP2010516625A (en) | 2007-01-24 | 2010-05-20 | インサート セラピューティクス， インコーポレイテッド | Polymer-drug conjugates with tether groups for controlled drug delivery |
| KR100904207B1 (en) | 2007-06-01 | 2009-06-25 | (주) 태웅메디칼 | Drug release coating for stents, preparation method thereof and drug release stent coated with the coating |
| JP2010539245A (en) | 2007-09-14 | 2010-12-16 | 日東電工株式会社 | Drug carrier |
| US8319002B2 (en) * | 2007-12-06 | 2012-11-27 | Nanosys, Inc. | Nanostructure-enhanced platelet binding and hemostatic structures |
| WO2009073854A1 (en) | 2007-12-06 | 2009-06-11 | Nanosys, Inc. | Resorbable nanoenhanced hemostatic structures and bandage materials |
| WO2009152479A1 (en) * | 2008-06-12 | 2009-12-17 | University Of Alabama Huntsville | Compositions comprising nitric oxide or nitric oxide donors for the treatment of neurodegenerative diseases of trauma |
| EP2320728A4 (en) * | 2008-07-21 | 2013-03-13 | Osiris Therapeutics Inc | Taxane compounds for treating eye disease |
| US8888840B2 (en) * | 2009-05-20 | 2014-11-18 | Boston Scientific Scimed, Inc. | Drug eluting medical implant |
| US20110319987A1 (en) | 2009-05-20 | 2011-12-29 | Arsenal Medical | Medical implant |
| US9265633B2 (en) | 2009-05-20 | 2016-02-23 | 480 Biomedical, Inc. | Drug-eluting medical implants |
| US8992601B2 (en) | 2009-05-20 | 2015-03-31 | 480 Biomedical, Inc. | Medical implants |
| EP2432425B1 (en) | 2009-05-20 | 2018-08-08 | 480 Biomedical, Inc. | Medical implant |
| US9309347B2 (en) | 2009-05-20 | 2016-04-12 | Biomedical, Inc. | Bioresorbable thermoset polyester/urethane elastomers |
| US8372133B2 (en) | 2009-10-05 | 2013-02-12 | 480 Biomedical, Inc. | Polymeric implant delivery system |
| WO2011063339A1 (en) * | 2009-11-23 | 2011-05-26 | Cardioxyl Pharmaceuticals, Inc. | Nitroxyl donors for the treatment of pulmonary hypertension |
| JP5826762B2 (en) * | 2009-12-07 | 2015-12-02 | ザ ジョンズ ホプキンス ユニバーシティ | N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivatives |
| IN2012DN05028A (en) | 2009-12-07 | 2015-10-23 | Univ Johns Hopkins | |
| EP2519467B1 (en) | 2009-12-28 | 2020-09-09 | Colorado State University Research Foundation | Modular biocompatible materials for medical devices and uses thereof |
| US8398916B2 (en) | 2010-03-04 | 2013-03-19 | Icon Medical Corp. | Method for forming a tubular medical device |
| WO2012116177A2 (en) * | 2011-02-24 | 2012-08-30 | Colorado State University Research Foundation | Materials for modulating biological responses and methods of making |
| JP2015505557A (en) * | 2012-01-31 | 2015-02-23 | セルリアン・ファーマ・インコーポレイテッド | Polymers based on cyclodextrins for therapeutic delivery |
| WO2014046671A1 (en) * | 2012-09-21 | 2014-03-27 | Michigan Technological University | No-releasing polymers and uses thereof |
| US20140094432A1 (en) | 2012-10-02 | 2014-04-03 | Cerulean Pharma Inc. | Methods and systems for polymer precipitation and generation of particles |
| EP3160397A4 (en) | 2014-06-24 | 2018-03-21 | Icon Medical Corp. | Improved metal alloys for medical devices |
| RU2018113280A (en) | 2015-09-16 | 2019-10-16 | ДиЭфБи СОРИА, ЭлЭлСи | DELIVERY OF MEDICINE NANOPARTICLES AND METHODS OF USE THEREOF |
| US11766506B2 (en) | 2016-03-04 | 2023-09-26 | Mirus Llc | Stent device for spinal fusion |
| WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
| US11096781B2 (en) | 2016-08-01 | 2021-08-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
| KR102658256B1 (en) | 2017-03-15 | 2024-04-16 | 디에프비 소리아, 엘엘씨 | Topical therapy for the treatment of skin malignancies using taxane nanoparticles. |
| WO2018191415A1 (en) | 2017-04-11 | 2018-10-18 | Colorado State University Research Foundation | Functionalization of metal-organic frameworks |
| EP3651580A4 (en) | 2017-07-11 | 2021-04-21 | Colorado State University Research Foundation | CHITOSAN COMPOSITE MATERIAL AND METALLO-ORGANIC STRUCTURE |
| JP7372252B2 (en) | 2018-03-16 | 2023-10-31 | ディーエフビー ソリア リミテッド ライアビリティ カンパニー | Local therapy for the treatment of cervical intraepithelial neoplasia (CIN) and cervical cancer using nanoparticles of taxanes |
| MX2023001749A (en) | 2020-08-24 | 2023-04-11 | Edwards Lifesciences Corp | Methods and systems for aligning a commissure of a prosthetic heart valve with a commissure of a native valve. |
Family Cites Families (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666884A (en) | 1984-04-10 | 1987-05-19 | New England Deaconess Hospital | Method of inhibiting binding of von Willebrand factor to human platelets and inducing interaction of platelets with vessel walls |
| US4885173A (en) | 1985-05-01 | 1989-12-05 | University Of Utah | Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities |
| US5157049A (en) | 1988-03-07 | 1992-10-20 | The United States Of America As Represented By The Department Of Health & Human Services | Method of treating cancers sensitive to treatment with water soluble derivatives of taxol |
| US4900719A (en) | 1988-08-05 | 1990-02-13 | The Ohio State University | Nitrosothiols as hypotensive agents |
| US4960790A (en) | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
| EP0533816B1 (en) | 1990-06-15 | 1995-06-14 | Cortrak Medical, Inc. | Drug delivery apparatus |
| US5998656A (en) | 1991-09-23 | 1999-12-07 | Florida State University | C10 tricyclic taxanes |
| US5284864A (en) | 1991-09-23 | 1994-02-08 | Florida State University | Butenyl substituted taxanes and pharmaceutical compositions containing them |
| US5399726A (en) | 1993-01-29 | 1995-03-21 | Florida State University | Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups |
| US6028205A (en) | 1991-09-23 | 2000-02-22 | Florida State University | C2 tricyclic taxanes |
| US5990325A (en) | 1993-03-05 | 1999-11-23 | Florida State University | Process for the preparation of 9-desoxotaxol, 9-desoxobaccatin III and analogs thereof |
| US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5272171A (en) | 1992-02-13 | 1993-12-21 | Bristol-Myers Squibb Company | Phosphonooxy and carbonate derivatives of taxol |
| US5407816A (en) | 1992-02-20 | 1995-04-18 | Phyton Catalytic, Inc. | Enhanced production of taxol and taxanes by cell cultures of taxus species |
| US5278192A (en) | 1992-07-02 | 1994-01-11 | The Research Foundation Of State University Of New York | Method of vasodilator therapy for treating a patient with a condition |
| FR2698871B1 (en) | 1992-12-09 | 1995-02-24 | Rhone Poulenc Rorer Sa | New taxoids, their preparation and the pharmaceutical compositions containing them. |
| US5646176A (en) | 1992-12-24 | 1997-07-08 | Bristol-Myers Squibb Company | Phosphonooxymethyl ethers of taxane derivatives |
| IL108316A (en) | 1993-01-15 | 2006-10-31 | Univ Florida State | C10 taxane derivatives and pharmaceutical compositions containing them |
| US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| EP0682660B1 (en) * | 1993-02-05 | 2003-11-05 | Bryn Mawr College | Synthesis of taxol, analogs and intermediates with variable a-ring side chains |
| US5464650A (en) | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
| US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| SI0703909T1 (en) | 1993-06-11 | 2000-08-31 | Pharmacia & Upjohn Company | Delta 6,7 -taxols antineoplastic use and pharmaceutical compositions containing them |
| US5852058A (en) | 1993-06-11 | 1998-12-22 | The Board Of Trustees Of The Leland Stanford Junior University | Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury |
| US5861168A (en) | 1993-06-11 | 1999-01-19 | The Board Of Trustees Of The Leland Stanford Junior University | Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury |
| US5428070A (en) | 1993-06-11 | 1995-06-27 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of vascular degenerative diseases by modulation of endogenous nitric oxide production of activity |
| US5945452A (en) | 1993-06-11 | 1999-08-31 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of vascular degenerative diseases by modulation of endogenous nitric oxide production or activity |
| US5994341A (en) | 1993-07-19 | 1999-11-30 | Angiogenesis Technologies, Inc. | Anti-angiogenic Compositions and methods for the treatment of arthritis |
| JP4850985B2 (en) * | 1993-07-29 | 2012-01-11 | アメリカ合衆国 | Method for treating atherosclerosis or restenosis using microtubule stabilizer |
| CA2129288C (en) | 1993-08-17 | 2000-05-16 | Jerzy Golik | Phosphonooxymethyl esters of taxane derivatives |
| IL127597A (en) | 1994-01-28 | 2003-07-31 | Upjohn Co | Iso-taxol analogs |
| US5482925A (en) | 1994-03-17 | 1996-01-09 | Comedicus Incorporated | Complexes of nitric oxide with cardiovascular amines as dual acting cardiovascular agents |
| NZ288802A (en) | 1994-06-28 | 1998-05-27 | Upjohn Co | Ether taxol derivatives, preparation and pharmaceutical compositions thereof |
| US5629433A (en) | 1994-07-18 | 1997-05-13 | Hauser, Inc. | Selective process for the deacylation and deacetylation of taxol and taxanes |
| WO1996011008A1 (en) | 1994-10-06 | 1996-04-18 | New York University | Administration of a 27-hydroxycholesterol or prodrug thereof as an anti-cancer agent |
| US6100411A (en) | 1994-10-28 | 2000-08-08 | The Research Foundation Of State University Of New York | Taxoid anti-tumor agents and pharmaceutical compositions thereof |
| US5719177A (en) | 1994-11-04 | 1998-02-17 | Pharmacia S.P.A. | Taxane derivatives |
| GB9423868D0 (en) | 1994-11-25 | 1995-01-11 | Wellcome Found | Compounds for use in medicine |
| EP1609477B1 (en) | 1994-12-12 | 2011-11-09 | Omeros Corporation | Irrigation solution and use thereof for the perioperative inhibition of pain/inflammation and/or spasm at a vascular structure |
| US5679807A (en) | 1995-01-30 | 1997-10-21 | Hauser, Inc. | Preparation of taxol and docetaxel through primary amines |
| US6063407A (en) | 1995-02-16 | 2000-05-16 | The General Hospital Corporation | Treatment of vascular thrombosis and restenosis with inhaled nitric oxide |
| US6231600B1 (en) | 1995-02-22 | 2001-05-15 | Scimed Life Systems, Inc. | Stents with hybrid coating for medical devices |
| US5665077A (en) | 1995-04-24 | 1997-09-09 | Nitrosci Pharmaceuticals Llc | Nitric oxide-releasing nitroso compositions and methods and intravascular devices for using them to prevent restenosis |
| CA2178541C (en) | 1995-06-07 | 2009-11-24 | Neal E. Fearnot | Implantable medical device |
| US5780653A (en) * | 1995-06-07 | 1998-07-14 | Vivorx Pharmaceuticals, Inc. | Nitrophenyl, 10-deacetylated substituted taxol derivatives as dual functional cytotoxic/radiosensitizers |
| ES2179208T3 (en) | 1995-09-12 | 2003-01-16 | Elan Pharm Inc | TAXAN HYDROPHOBE DERIVATIVES THAT FAVOR HYDROLYSIS. |
| WO1997009979A1 (en) * | 1995-09-13 | 1997-03-20 | Florida State University | Radiosensitizing taxanes and their pharmaceutical preparations |
| US6177456B1 (en) | 1995-10-02 | 2001-01-23 | Xechem International, Inc. | Monohalocephalomannines having anticancer and antileukemic activity and method of preparation therefor |
| WO1997019938A1 (en) | 1995-11-29 | 1997-06-05 | Consejo Superior Investigaciones Cientificas | Fluorescent derivatives of paclitaxel and docetaxel with antineoplastic activity, method for producing them and their applications |
| US5760072A (en) | 1995-12-29 | 1998-06-02 | Pharmachemie B.V. | Paclitaxel prodrugs, method for preparation as well as their use in selective chemotherapy |
| US5688977A (en) | 1996-02-29 | 1997-11-18 | Napro Biotherapeutics, Inc. | Method for docetaxel synthesis |
| US5951458A (en) | 1996-02-29 | 1999-09-14 | Scimed Life Systems, Inc. | Local application of oxidizing agents to prevent restenosis |
| PL189698B1 (en) | 1996-03-12 | 2005-09-30 | Pg Txl Co | Water-soluble promedicines of paklitaxel |
| US6441025B2 (en) | 1996-03-12 | 2002-08-27 | Pg-Txl Company, L.P. | Water soluble paclitaxel derivatives |
| CA2255615C (en) * | 1996-05-22 | 2006-08-29 | Neuromedica, Inc. | Compositions comprising conjugates of cis-docosahexaenoic acid and docetaxel |
| US5919815A (en) | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
| WO1998000419A1 (en) | 1996-07-02 | 1998-01-08 | Bristol-Myers Squibb Company | Ortho-ester analogs of paclitaxel |
| US5797887A (en) | 1996-08-27 | 1998-08-25 | Novovasc Llc | Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation |
| IT1295694B1 (en) | 1996-11-14 | 1999-05-27 | Nicox Sa | NITROXIS DERIVATIVES FOR THE PREPARATION OF MEDICATIONS WITH ANTI-THROMBINIC ACTIVITY |
| US6515016B2 (en) | 1996-12-02 | 2003-02-04 | Angiotech Pharmaceuticals, Inc. | Composition and methods of paclitaxel for treating psoriasis |
| US6495579B1 (en) | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
| US5977386A (en) | 1996-12-24 | 1999-11-02 | Bristol-Myers Squibb Company | 6-thio-substituted paclitaxels |
| US5902822A (en) | 1997-02-28 | 1999-05-11 | Bristol-Myers Squibb Company | 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels |
| US5912264A (en) | 1997-03-03 | 1999-06-15 | Bristol-Myers Squibb Company | 6-halo-or nitrate-substituted paclitaxels |
| US6017935A (en) | 1997-04-24 | 2000-01-25 | Bristol-Myers Squibb Company | 7-sulfur substituted paclitaxels |
| DE19718339A1 (en) | 1997-04-30 | 1998-11-12 | Schering Ag | Polymer coated stents, processes for their manufacture and their use for restenosis prophylaxis |
| KR100428634B1 (en) | 1997-07-11 | 2004-11-03 | 주식회사 코오롱 | Preparation of Taxol Using Fungi |
| JPH1192468A (en) | 1997-09-17 | 1999-04-06 | Yakult Honsha Co Ltd | New taxane derivatives |
| WO1999018949A1 (en) | 1997-10-15 | 1999-04-22 | Thomas Jefferson University | Nitric oxide donor compositions, methods, apparatus, and kits for preventing or alleviating vasoconstriction or vasospasm in a mammal |
| US5994444A (en) | 1997-10-16 | 1999-11-30 | Medtronic, Inc. | Polymeric material that releases nitric oxide |
| US20020164374A1 (en) | 1997-10-29 | 2002-11-07 | John Jackson | Polymeric systems for drug delivery and uses thereof |
| US6150537A (en) | 1997-12-12 | 2000-11-21 | Emory University | Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents |
| AU3771799A (en) | 1998-04-30 | 1999-11-16 | Johns Hopkins University, The | Treatment of advanced decompensated heart failure with nitric oxide donors |
| KR20010043230A (en) | 1998-05-01 | 2001-05-25 | 패트리샤 에이, 필리어 | Methods and useful intermediates for paclitaxel synthesis from c-7, c-10 di-cbz baccatin iii |
| US5981564A (en) | 1998-07-01 | 1999-11-09 | Universite Laval | Water-soluble derivatives of paclitaxel, method for producing same and uses thereof |
| US5916913A (en) | 1998-08-03 | 1999-06-29 | Joseph; Hazel L. | Inhibition of wound contraction with paclitaxel, colchicine and penicillamine |
| ATE218560T1 (en) | 1998-08-21 | 2002-06-15 | Pharmachemie Bv | WATER-SOLUBLE SIMILAR COMPOUNDS AND PRODUCTS OF PACLITAXEL |
| US6017948A (en) | 1998-10-30 | 2000-01-25 | Supergen, Inc. | Water-miscible pharmaceutical compositions |
| US6071952A (en) | 1998-12-02 | 2000-06-06 | Mylan Pharmaceuticals, Inc. | Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents |
| IT1311924B1 (en) | 1999-04-13 | 2002-03-20 | Nicox Sa | PHARMACEUTICAL COMPOUNDS. |
| IT1311921B1 (en) | 1999-04-13 | 2002-03-20 | Nicox Sa | PHARMACEUTICAL COMPOUNDS. |
| IT1311923B1 (en) | 1999-04-13 | 2002-03-20 | Nicox Sa | PHARMACEUTICAL COMPOUNDS. |
| JP2003506142A (en) | 1999-08-04 | 2003-02-18 | シー・アール・バード・インク | Medical devices that release nitric oxide |
| IT1314184B1 (en) | 1999-08-12 | 2002-12-06 | Nicox Sa | PHARMACEUTICAL COMPOSITIONS FOR THE THERAPY OF STRESS-OXIDATIVE CONDITIONS |
-
2001
- 2001-06-22 US US09/886,494 patent/US6656966B2/en not_active Expired - Fee Related
- 2001-06-22 DE DE60131537T patent/DE60131537T2/en not_active Expired - Fee Related
- 2001-06-22 AU AU2001270070A patent/AU2001270070B2/en not_active Ceased
- 2001-06-22 EP EP01948610A patent/EP1301500B1/en not_active Expired - Lifetime
- 2001-06-22 JP JP2002504242A patent/JP2004501143A/en active Pending
- 2001-06-22 WO PCT/US2001/019939 patent/WO2001098286A1/en not_active Ceased
- 2001-06-22 AU AU7007001A patent/AU7007001A/en active Pending
- 2001-06-22 CA CA002410632A patent/CA2410632A1/en not_active Abandoned
-
2003
- 2003-10-14 US US10/682,923 patent/US6869973B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2001270070A1 (en) | Nitrosated and nitrosylated taxanes, compositions and methods of use | |
| AU7007001A (en) | Nitrosated and nitrosylated taxanes, compositions and methods of use | |
| IL150368A0 (en) | Nitrosated and nitrosylated cyclooxygenase-2-inhibitors, compositions and methods of use | |
| AU2003293529A1 (en) | Nitrosated and nitrosylated rapamycin compounds, compositions and methods of use | |
| AU2003291668A1 (en) | Sacrificial compositions, methods of use thereof, and methods of decomposition thereof | |
| AU4841700A (en) | Nitrosated and nitrosylated potassium channel activators, compositions and methods of use | |
| AU2002357119A1 (en) | Mitocidal compositions and methods | |
| AU2003259735A1 (en) | Small-mer compositions and methods of use | |
| AU3713600A (en) | Nitrosated and nitrosylated prostaglandins, compositions and metods of use | |
| AU2003299441A1 (en) | Nf-hev compositions and methods of use | |
| AU2001261194A1 (en) | Novel members of the lysyl oxidases family of amine oxidases related applications | |
| AU2002357748A1 (en) | Osteopontin-related compositions and methods | |
| AU2002251140A1 (en) | Chemical derivatives and their use as anti-telomerase agent | |
| AU2756301A (en) | Compositions comprising genome segments and methods of using the same | |
| AU5179800A (en) | Mycolactone and related compounds, compositions and methods of use | |
| AU2001238091A1 (en) | Tgf-beta therapeutics, compositions and methods of use | |
| AU2002359869A1 (en) | Pak5-related compositions and methods | |
| AU2003238034A1 (en) | Novel use of imidazotriazinones | |
| AU2001258330A1 (en) | New uses of imidazolylmethyl-pyridines | |
| AU2002229859A1 (en) | Chemical derivatives and their use as anti-telomerase agent | |
| AU2002319505A1 (en) | Hair extension kits | |
| AU2001249940A1 (en) | Aminoflavone compounds, compositions, and methods of use thereof | |
| AU2002331660A1 (en) | Supported fluridone compositions and methods | |
| HK1051489A (en) | Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use | |
| HK1090923A (en) | Novel spiroindoline or spiroisoquinoline compounds, methods of use and compositions thereof |