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AU2001268661A1 - 20-fluoro-17(20)-vinyl steroids as inhibitors of c17-20-lyase and 5-alpha reductase - Google Patents

20-fluoro-17(20)-vinyl steroids as inhibitors of c17-20-lyase and 5-alpha reductase

Info

Publication number
AU2001268661A1
AU2001268661A1 AU2001268661A AU6866101A AU2001268661A1 AU 2001268661 A1 AU2001268661 A1 AU 2001268661A1 AU 2001268661 A AU2001268661 A AU 2001268661A AU 6866101 A AU6866101 A AU 6866101A AU 2001268661 A1 AU2001268661 A1 AU 2001268661A1
Authority
AU
Australia
Prior art keywords
lyase
fluoro
inhibitors
alpha reductase
steroids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001268661A
Inventor
Joseph P. Burkhart
Cynthia A. Gates
Norton P. Peet
Philip M. Weintraub
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Publication of AU2001268661A1 publication Critical patent/AU2001268661A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
AU2001268661A 2000-06-27 2001-06-21 20-fluoro-17(20)-vinyl steroids as inhibitors of c17-20-lyase and 5-alpha reductase Abandoned AU2001268661A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21456100P 2000-06-27 2000-06-27
US60214561 2000-06-27
US29088101P 2001-05-14 2001-05-14
US60290881 2001-05-14
PCT/US2001/019889 WO2002000681A1 (en) 2000-06-27 2001-06-21 20-fluoro-17(20)-vinyl steroids as inhibitors of c17-20-lyase and 5-alpha reductase

Publications (1)

Publication Number Publication Date
AU2001268661A1 true AU2001268661A1 (en) 2002-01-08

Family

ID=26909117

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001268661A Abandoned AU2001268661A1 (en) 2000-06-27 2001-06-21 20-fluoro-17(20)-vinyl steroids as inhibitors of c17-20-lyase and 5-alpha reductase

Country Status (3)

Country Link
EP (1) EP1409512A1 (en)
AU (1) AU2001268661A1 (en)
WO (1) WO2002000681A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10043846A1 (en) * 2000-09-04 2002-04-04 Jenapharm Gmbh 17-methylene steroids, process for their preparation and pharmaceutical compositions containing them
DE10141984A1 (en) 2001-08-28 2003-03-20 Jenapharm Gmbh New 17-methylene-4-azasteroids
DE102006008074B4 (en) * 2006-02-22 2013-08-14 RUHR-UNIVERSITäT BOCHUM Treatment of cancer with olfactory receptor ligands
WO2008042898A2 (en) 2006-10-02 2008-04-10 Cortendo Invest, Ab Ketoconazole enantiomer in humans
GB201102913D0 (en) 2011-02-18 2011-04-06 Univ Birmingham Novel therapeutic

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3364238A (en) * 1966-04-04 1968-01-16 Searle & Co 3-oxygenated spiro[androstene-17, 1'-cycloprop-2'-ene], 2', 3'-dihydro derivatives corresponding and intermediates thereto
US5994334A (en) * 1997-02-05 1999-11-30 University Of Maryland Androgen synthesis inhibitors

Also Published As

Publication number Publication date
WO2002000681A1 (en) 2002-01-03
EP1409512A1 (en) 2004-04-21

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