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AU2001264657A1 - Crf receptor antagonists - Google Patents

Crf receptor antagonists

Info

Publication number
AU2001264657A1
AU2001264657A1 AU2001264657A AU6465701A AU2001264657A1 AU 2001264657 A1 AU2001264657 A1 AU 2001264657A1 AU 2001264657 A AU2001264657 A AU 2001264657A AU 6465701 A AU6465701 A AU 6465701A AU 2001264657 A1 AU2001264657 A1 AU 2001264657A1
Authority
AU
Australia
Prior art keywords
receptor antagonists
crf receptor
crf
antagonists
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001264657A
Inventor
Brian P. Dyck
Zhiqiang Guo
Mustapha Haddach
Charles Q. Huang
James R. Mccarthy
Jodie Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurocrine Biosciences Inc
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Publication of AU2001264657A1 publication Critical patent/AU2001264657A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001264657A 2000-05-18 2001-05-17 Crf receptor antagonists Abandoned AU2001264657A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/574,751 US6531475B1 (en) 1998-11-12 2000-05-18 CRF receptor antagonists and methods relating thereto
US09574751 2000-05-18
PCT/US2001/016048 WO2001087885A1 (en) 2000-05-18 2001-05-17 Crf receptor antagonists

Publications (1)

Publication Number Publication Date
AU2001264657A1 true AU2001264657A1 (en) 2001-11-26

Family

ID=24297480

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001264657A Abandoned AU2001264657A1 (en) 2000-05-18 2001-05-17 Crf receptor antagonists

Country Status (3)

Country Link
US (3) US6531475B1 (en)
AU (1) AU2001264657A1 (en)
WO (1) WO2001087885A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6531475B1 (en) * 1998-11-12 2003-03-11 Neurocrine Biosciences, Inc. CRF receptor antagonists and methods relating thereto
US7273871B2 (en) * 2001-07-17 2007-09-25 Sb Pharmco Puerto Rico Inc. Phenyl-5,6,6A,7,8,9-hexahydro-4H-1,4,9-triaza-phenalene derivatives as CRF antagonists
EP2335700A1 (en) 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
NZ544301A (en) 2003-06-25 2008-08-29 Ono Pharmaceutical Co Methanesulfonic acid salt of pyrazolopyrimidine compound, crystal thereof, and process for producing the same
US20060024661A1 (en) * 2003-07-30 2006-02-02 The Regents Of The University Of California Modulation of CRF potentiation of NMDA receptor currents via CRF receptor 2
EP1722826A2 (en) * 2004-02-13 2006-11-22 SB Pharmco Puerto Rico Inc. Crf receptor antagonists, their preparations, their pharmaceutical composition and their uses
BRPI0507861A (en) 2004-02-20 2007-07-17 Boehringer Ingelheim Int viral polymerase inhibitors
US7869958B2 (en) * 2004-08-09 2011-01-11 Research Development Foundation Structure-based modulators of B1 G-protein coupled receptors
ES2326827T3 (en) * 2004-10-19 2009-10-20 Smithkline Beecham (Cork) Limited ANATAGONISTS OF THE RECEIVER OF CRF AND RELATED METHODS.
CA2615946A1 (en) * 2005-07-22 2007-02-01 Sunesis Pharmaceuticals, Inc. Pyrazolo pyrimidines useful as aurora kinase inhibitors
AU2008211729A1 (en) * 2007-02-01 2008-08-07 Astrazeneca Ab 5,6,7,8-tetrahydropteridine derivatives as HSP90 inhibitors
TW201102390A (en) * 2009-03-31 2011-01-16 Arqule Inc Substituted pyrazolo-pyrimidine compounds
SI2440558T1 (en) 2009-06-08 2015-10-30 Takeda Pharmaceutical Company Limited Dihydropyrrolonaphtyridinone compounds as inhibitors of jak
EP2519525A4 (en) * 2009-12-30 2013-06-12 Arqule Inc SUBSTITUTED PYRROLOAMINOPYRIMIDINE COMPOUNDS
AU2012244549B2 (en) 2011-04-21 2017-04-20 Origenis Gmbh Heterocyclic compounds as kinase inhibitors
BR112013026521A2 (en) * 2011-04-21 2016-12-27 Origenis Gmbh pyrazolo [4,3-d] pyrimidines useful as kinase inhibitors
US9637491B2 (en) 2012-10-19 2017-05-02 Origenis Gmbh Pyrazolo[4,3-D]pyrimidines as kinase inhibitors
WO2014060113A1 (en) 2012-10-19 2014-04-24 Origenis Gmbh Novel kinase inhibitors
MX389004B (en) 2014-01-21 2025-03-20 Neurocrine Biosciences Inc CORTICOTROPIN-RELEASING FACTOR (CRF1) RECEPTOR ANTAGONISTS FOR THE TREATMENT OF CONGENITAL ADRENAL HYPERPLASIA.
ES2751698T3 (en) * 2014-11-03 2020-04-01 Olon Spa Procedure for the preparation of 1- (2-halogen-ethyl) -4-piperidine-carboxylic acid ethyl ester
MA54395A (en) 2018-12-07 2022-03-16 Neurocrine Biosciences Inc CRF1 RECEPTOR ANTAGONIST, PHARMACEUTICAL FORMULATIONS AND CORRESPONDING SOLID FORM FOR THE TREATMENT OF CONGENITAL ADRENAL HYPERPLASIA
WO2021062246A1 (en) 2019-09-27 2021-04-01 Neurocrine Biosciences, Inc. Crf receptor antagonists and methods of use
WO2022221182A1 (en) * 2021-04-12 2022-10-20 Jnana Therapeutics Inc. Small molecule inhibitors of mammalian slc34a1 function
CN115594634B (en) * 2022-10-26 2024-10-01 浙江工业大学 A new process for continuous preparation of 4-nitropyrazole

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605642A (en) 1984-02-23 1986-08-12 The Salk Institute For Biological Studies CRF antagonists
US4904658A (en) 1988-04-15 1990-02-27 American Cyanamid Company Substituted-6H,8H-pyrimido-[1,2,3-cd]purine-8,10-(9H)-diones and substituted-6H,10H-pyrimido[1,2-cd]purin-10-ones
US5063245A (en) 1990-03-28 1991-11-05 Nova Pharmaceutical Corporation Corticotropin-releasing factor antagonism compounds
FR2692893B1 (en) 1992-06-24 1994-09-02 Sanofi Elf Branched alkylamino thiazole derivatives, processes for their preparation and pharmaceutical compositions containing them.
BR9307659A (en) 1992-12-17 1999-06-29 Pfizer Pyrazoles and pyrazolopyrimidines having crf antagonistic activity
RU2124015C1 (en) 1992-12-17 1998-12-27 Пфайзер Инк. Derivatives of pyrrolo[2,3-d]pyrimidines, pharmaceutical composition, pyrrolo[2,3-d]pyrimidines, derivatives of pyrrole
RU2130453C1 (en) 1992-12-17 1999-05-20 Пфайзер Инк. Substituted pyrazoles, pharmaceutical composition based on said, method of patient treatment, intermediate compound
TW444018B (en) 1992-12-17 2001-07-01 Pfizer Pyrazolopyrimidines
TW336932B (en) 1992-12-17 1998-07-21 Pfizer Amino-substituted pyrazoles
WO1995010506A1 (en) 1993-10-12 1995-04-20 The Du Pont Merck Pharmaceutical Company 1n-alkyl-n-arylpyrimidinamines and derivatives thereof
TW530047B (en) 1994-06-08 2003-05-01 Pfizer Corticotropin releasing factor antagonists
CN1056611C (en) 1994-06-16 2000-09-20 美国辉瑞有限公司 Pyrazolo and pyrrolopyridines
US6020492A (en) 1995-05-12 2000-02-01 Neurogen Corporation Deazapurine derivatives; a new class of CRF1 specific ligands
FR2735777B1 (en) 1995-06-21 1997-09-12 Sanofi Sa 4-PHENYLAMINOTHIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US6107300A (en) 1996-03-27 2000-08-22 Dupont Pharmaceuticals Arylamino fused pyrimidines
ZA973884B (en) * 1996-05-23 1998-11-06 Du Pont Merck Pharma Tetrahydropteridines and pyridylpiperazines for treatment of neurological disorders
IL127566A0 (en) * 1996-08-28 1999-10-28 Pfizer Substituted 6,5-hetero- bicyclic derivatives
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
ATE225349T1 (en) * 1998-11-12 2002-10-15 Neurocrine Biosciences Inc CRF RECEPTOR ANTAGONISTS AND RELATED METHODS
US6531475B1 (en) * 1998-11-12 2003-03-11 Neurocrine Biosciences, Inc. CRF receptor antagonists and methods relating thereto

Also Published As

Publication number Publication date
US20040087589A1 (en) 2004-05-06
US20040157851A1 (en) 2004-08-12
US6531475B1 (en) 2003-03-11
WO2001087885A1 (en) 2001-11-22

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