|
NZ522444A
(en)
*
|
2000-05-19 |
2004-09-24 |
Genentech Inc |
Gene detection assay for improving the likelihood of an effective response to an ErbB antagonist cancer therapy
|
|
AU2004217434B2
(en)
*
|
2000-12-08 |
2010-08-26 |
Alexion Pharmaceuticals, Inc. |
Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
|
|
US9249229B2
(en)
*
|
2000-12-08 |
2016-02-02 |
Alexion Pharmaceuticals, Inc. |
Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
|
|
US7408041B2
(en)
*
|
2000-12-08 |
2008-08-05 |
Alexion Pharmaceuticals, Inc. |
Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
|
|
US20040198661A1
(en)
*
|
2000-12-08 |
2004-10-07 |
Bowdish Katherine S. |
Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
|
|
US20060057651A1
(en)
*
|
2000-12-08 |
2006-03-16 |
Bowdish Katherine S |
Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
|
|
WO2002059280A2
(en)
*
|
2000-12-08 |
2002-08-01 |
Alexion Pharmaceuticals, Inc. |
Chronic lymphocytic leukemia cell line and its use for producing an antibody
|
|
US7452539B2
(en)
*
|
2001-12-19 |
2008-11-18 |
Genentech, Inc. |
Stabilizing polypeptides which have been exposed to urea
|
|
AU2003210549A1
(en)
*
|
2002-01-18 |
2003-09-02 |
Chiron Corporation |
Combination il-2/anti-herz antibody therapy for cancers characterized by overexpression of the her2 receptor protein
|
|
PT1531850E
(en)
*
|
2002-06-07 |
2012-05-07 |
Zymogenetics Inc |
Use of il-21 and monoclonal antibody for treating solid cancers
|
|
EP2357005A1
(en)
|
2002-07-01 |
2011-08-17 |
Wilex AG |
Co-administration of CG250 and IL-2 or IFN-alpha for treating cancer such as renal cell carcinomas
|
|
CN102188704B
(en)
*
|
2004-05-20 |
2013-04-24 |
津莫吉尼蒂克斯公司 |
Methods of treating cancer using IL-21 and monoclonal antibody therapy
|
|
BRPI0518104B8
(en)
|
2005-01-21 |
2021-05-25 |
Genentech Inc |
industrialized article and use of her2 antibody
|
|
BRPI0606839B8
(en)
|
2005-02-03 |
2021-12-14 |
Massachusetts Gen Hospital |
Use of a pharmaceutical composition comprising an irreversible epidermal growth factor receptor (egfr) inhibitor
|
|
RU2404806C2
(en)
*
|
2005-02-23 |
2010-11-27 |
Дженентек, Инк. |
Extension of time to progression of disease or lifetime of oncologic patients with application of her dimerisation inhibitors
|
|
TW200642695A
(en)
*
|
2005-03-08 |
2006-12-16 |
Genentech Inc |
Methods for identifying tumors responsive to treatment with her dimerization inhibitors (HDIs)
|
|
US8105768B2
(en)
|
2005-03-09 |
2012-01-31 |
Abbott Laboratories |
Methods of identifying patients for treatment with HER-2/neu inhibitors based on detection of HER-2/neu and TOP2A gene copy number
|
|
JP2006316040A
(en)
|
2005-05-13 |
2006-11-24 |
Genentech Inc |
HERCEPTIN® adjuvant therapy
|
|
RU2451524C2
(en)
*
|
2005-11-04 |
2012-05-27 |
Вайет |
Anti-tumour combinations mtor inhibitors, herceptin and/or hki-272
|
|
US20070111906A1
(en)
*
|
2005-11-12 |
2007-05-17 |
Milner Jeffrey L |
Relatively low viscosity transmission fluids
|
|
BRPI0707126A2
(en)
*
|
2006-01-12 |
2011-04-19 |
Alexion Pharma Inc |
ox-2 / cd200 antibodies and use of these
|
|
DE102006011507A1
(en)
*
|
2006-03-14 |
2007-09-20 |
Lts Lohmann Therapie-Systeme Ag |
Active substance-loaded nanoparticles based on hydrophilic proteins
|
|
ES2613957T3
(en)
|
2006-08-04 |
2017-05-29 |
Medimmune Limited |
Antibodies against ERBB2
|
|
CA2677108A1
(en)
|
2007-03-02 |
2008-09-12 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
|
US9551033B2
(en)
*
|
2007-06-08 |
2017-01-24 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
|
WO2008154249A2
(en)
|
2007-06-08 |
2008-12-18 |
Genentech, Inc. |
Gene expression markers of tumor resistance to her2 inhibitor treatment
|
|
AU2008279618B2
(en)
*
|
2007-07-25 |
2014-05-22 |
Alexion Pharmaceuticals, Inc. |
Methods and compositions for treating autoimmune disease
|
|
US8022216B2
(en)
|
2007-10-17 |
2011-09-20 |
Wyeth Llc |
Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
|
|
BRPI0812682A2
(en)
|
2008-06-16 |
2010-06-22 |
Genentech Inc |
metastatic breast cancer treatment
|
|
SG191676A1
(en)
|
2008-06-17 |
2013-07-31 |
Wyeth Llc |
Antineoplastic combinations containing hki-272 and vinorelbine
|
|
CN109464445A
(en)
|
2008-08-04 |
2019-03-15 |
惠氏有限责任公司 |
The antineoplastic combinations of 4- anilino- -3- cyano quinolines and capecitabine
|
|
EP2362783A2
(en)
|
2008-10-31 |
2011-09-07 |
Biogen Idec MA Inc. |
Light targeting molecules and uses thereof
|
|
EP2408817B1
(en)
|
2009-03-20 |
2016-03-16 |
F.Hoffmann-La Roche Ag |
Bispecific anti-her antibodies
|
|
SG174382A1
(en)
|
2009-04-06 |
2011-11-28 |
Wyeth Llc |
Treatment regimen utilizing neratinib for breast cancer
|
|
US20120121586A1
(en)
|
2009-05-29 |
2012-05-17 |
Astrid Kiermaier |
Modulators for her2 signaling in her2 expressing patients with gastric cancer
|
|
SG182408A1
(en)
|
2010-01-11 |
2012-08-30 |
Alexion Pharma Inc |
Biomarkers of immunomodulatory effects in humans treated with anti-cd200 antibodies
|
|
WO2011100538A1
(en)
|
2010-02-11 |
2011-08-18 |
Alexion Pharmaceuticals, Inc. |
Therapeutic methods using an ti-cd200 antibodies
|
|
SG183333A1
(en)
|
2010-02-18 |
2012-09-27 |
Genentech Inc |
Neuregulin antagonists and use thereof in treating cancer
|
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
|
EP2643353A1
(en)
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispecific molecules
|
|
JP5766296B2
(en)
|
2010-12-23 |
2015-08-19 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Polypeptide-polynucleotide complexes and their use in targeted delivery of effector components
|
|
CA2842375A1
(en)
|
2011-08-17 |
2013-02-21 |
Erica Jackson |
Neuregulin antibodies and uses thereof
|
|
WO2013063229A1
(en)
|
2011-10-25 |
2013-05-02 |
The Regents Of The University Of Michigan |
Her2 targeting agent treatment in non-her2-amplified cancers having her2 expressing cancer stem cells
|
|
CA2857114A1
(en)
|
2011-11-30 |
2013-06-06 |
Genentech, Inc. |
Erbb3 mutations in cancer
|
|
EP2788500A1
(en)
|
2011-12-09 |
2014-10-15 |
F.Hoffmann-La Roche Ag |
Identification of non-responders to her2 inhibitors
|
|
CN104220457A
(en)
|
2012-03-27 |
2014-12-17 |
霍夫曼-拉罗奇有限公司 |
Diagnosis and treatment involving HER3 inhibitors
|
|
EP3511718A1
(en)
|
2012-11-30 |
2019-07-17 |
F. Hoffmann-La Roche AG |
Pd-l1 inhibitor
|
|
KR101453462B1
(en)
*
|
2013-05-16 |
2014-10-23 |
앱클론(주) |
Antibodies Capable of Binding Specifically to HER2
|
|
HUE054529T2
(en)
|
2014-03-11 |
2021-09-28 |
Molecular Templates Inc |
Amino-terminal proximal Shiga toxin A proteins containing subunit effector regions and cell-targeting immunoglobulin-type binding regions capable of specifically binding CD38
|
|
EP3116905B1
(en)
|
2014-03-11 |
2019-01-30 |
Molecular Templates, Inc. |
Proteins comprising binding regions, shiga toxin a subunit effector regions, and carboxy-terminal, endoplasmic reticulum localization signal motifs
|
|
RU2016144176A
(en)
|
2014-04-11 |
2018-05-14 |
МЕДИММЬЮН, ЭлЭлСи |
SPECIFIC ANTIBODIES TO HER2
|
|
US9586056B2
(en)
|
2014-07-03 |
2017-03-07 |
Haniva Llc |
Combination therapy for treating cancer and method for treating cancer using a combination therapy
|
|
WO2016052971A1
(en)
*
|
2014-09-30 |
2016-04-07 |
가톨릭대학교 산학협력단 |
Herceptin-photosensitizer conjugate for breast cancer diagnosis and production method therefor
|
|
CN107849096B
(en)
|
2015-05-30 |
2022-05-24 |
分子模板公司 |
Deimmunized shiga toxin a subunit scaffolds and cell targeting molecules comprising them
|
|
HK1248258A1
(en)
|
2015-07-26 |
2018-10-12 |
Molecular Templates, Inc. |
Cell-targeting molecules comprising shiga toxin a subunit effectors and cd8+ t-cell epitopes
|
|
MA44334A
(en)
|
2015-10-29 |
2018-09-05 |
Novartis Ag |
ANTIBODY CONJUGATES INCLUDING A TOLL-TYPE RECEPTOR AGONIST
|
|
US20190151346A1
(en)
|
2016-05-10 |
2019-05-23 |
INSERM (Institute National de la Santé et de la Recherche Médicale) |
Combinations therapies for the treatment of cancer
|
|
US20200024312A1
(en)
|
2017-01-25 |
2020-01-23 |
Molecular Templates, Inc. |
Cell-targeting molecules comprising de-immunized, shiga toxin a subunit effectors and cd8+ t-cell epitopes
|
|
BR112019018915A2
(en)
|
2017-03-15 |
2020-04-14 |
Pandion Therapeutics Inc |
targeted immunotolerance
|
|
AR111651A1
(en)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
CONJUGATES OF ANTIBODIES THAT INCLUDE TOLL TYPE RECEIVER AGONISTS AND COMBINATION THERAPIES
|
|
KR20200010354A
(en)
|
2017-05-24 |
2020-01-30 |
팬디온 테라퓨틱스, 인코포레이티드 |
Targeted Immune Tolerance
|
|
WO2019067499A1
(en)
|
2017-09-27 |
2019-04-04 |
Alexion Pharmaceuticals, Inc. |
Biomarker signature for predicting tumor response to anti-cd200 therapy
|
|
US10946068B2
(en)
|
2017-12-06 |
2021-03-16 |
Pandion Operations, Inc. |
IL-2 muteins and uses thereof
|
|
US10174092B1
(en)
|
2017-12-06 |
2019-01-08 |
Pandion Therapeutics, Inc. |
IL-2 muteins
|
|
USRE50550E1
(en)
|
2017-12-06 |
2025-08-26 |
Pandion Operations, Inc. |
IL-2 muteins and uses thereof
|
|
US11802154B2
(en)
|
2017-12-20 |
2023-10-31 |
Alexion Pharmaceuticals, Inc. |
Humanized anti-CD200 antibodies and uses thereof
|
|
US12139533B2
(en)
|
2017-12-20 |
2024-11-12 |
Alexion Pharmaceuticals, Inc. |
Liquid formulations of anti-CD200 antibodies
|
|
MX2019009726A
(en)
|
2018-04-17 |
2020-02-05 |
Molecular Templates Inc |
Her2-targeting molecules comprising de-immunized, shiga toxin a subunit scaffolds.
|
|
MX2021014178A
(en)
|
2019-05-20 |
2022-01-04 |
Pandion Operations Inc |
Madcam targeted immunotolerance.
|
|
WO2021168079A1
(en)
|
2020-02-21 |
2021-08-26 |
Pandion Operations, Inc. |
Tissue targeted immunotolerance with a cd39 effector
|