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AU2001261463A1 - Magnetic bead-based arrays - Google Patents

Magnetic bead-based arrays

Info

Publication number
AU2001261463A1
AU2001261463A1 AU2001261463A AU6146301A AU2001261463A1 AU 2001261463 A1 AU2001261463 A1 AU 2001261463A1 AU 2001261463 A AU2001261463 A AU 2001261463A AU 6146301 A AU6146301 A AU 6146301A AU 2001261463 A1 AU2001261463 A1 AU 2001261463A1
Authority
AU
Australia
Prior art keywords
magnetic bead
based arrays
arrays
bead
magnetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001261463A
Inventor
Chong H. Ahn
Hyoung J. Cho
Jin-Woo Choi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Cincinnati
Original Assignee
University of Cincinnati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Cincinnati filed Critical University of Cincinnati
Publication of AU2001261463A1 publication Critical patent/AU2001261463A1/en
Abandoned legal-status Critical Current

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    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/18Magnetic separation whereby the particles are suspended in a liquid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical or biological applications
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    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
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    • C40B70/00Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/34Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G01N2030/347Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient mixers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

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Families Citing this family (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US9709559B2 (en) * 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US7892854B2 (en) * 2000-06-21 2011-02-22 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US20020166760A1 (en) * 2001-05-11 2002-11-14 Prentiss Mara G. Micromagentic systems and methods for microfluidics
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US7314599B2 (en) 2001-07-17 2008-01-01 Agilent Technologies, Inc. Paek embossing and adhesion for microfluidic devices
CA2741049C (en) 2001-10-15 2019-02-05 Bioarray Solutions, Ltd. Multiplexed analysis of polymorphic loci by probe elongation-mediated detection
US20040234898A1 (en) * 2002-02-06 2004-11-25 Batishko Charles R. Magnetic flowcell systems and methods
US20040027846A1 (en) * 2002-08-06 2004-02-12 Thaddeus Schroeder Method for forming ferromagnetic targets for position sensors
NL1021264C2 (en) * 2002-08-13 2004-02-17 Lionix B V Production of micropacking for chemical analysis systems, by converting material applied to substrate into mould and then applying second material
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US7062840B2 (en) * 2003-02-24 2006-06-20 Delphi Technologies, Inc. Method for forming permanent magnet targets for position sensors
US7229746B2 (en) * 2003-04-02 2007-06-12 Delphi Technologies, Inc. Printed high strength permanent magnet targets for magnetic sensors
DE10321809A1 (en) * 2003-05-14 2005-03-17 Micronas Holding Gmbh Process for printing biomolecules
US7927796B2 (en) * 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
PT1664722E (en) * 2003-09-22 2011-12-28 Bioarray Solutions Ltd Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
CA2544041C (en) 2003-10-28 2015-12-08 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
US20050089916A1 (en) * 2003-10-28 2005-04-28 Xiongwu Xia Allele assignment and probe selection in multiplexed assays of polymorphic targets
NZ547495A (en) 2003-10-29 2008-05-30 Bioarray Solutions Ltd Multiplexed nucleic acid analysis by fragmentation of double-stranded DNA
US20070207055A1 (en) * 2003-10-31 2007-09-06 Commissariat A L'energie Atomique Operating Device Comprising A Localized Zone For The Capture Of A Drop A Liquid Of Interest
JPWO2005042622A1 (en) * 2003-10-31 2007-12-13 トライアル株式会社 Polyolefin magnetic microparticles with functional groups on the surface
US8398295B2 (en) * 2004-01-28 2013-03-19 Drexel University Magnetic fluid manipulators and methods for their use
US7363170B2 (en) * 2004-07-09 2008-04-22 Bio Array Solutions Ltd. Transfusion registry network providing real-time interaction between users and providers of genetically characterized blood products
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
JP2006122017A (en) * 2004-11-01 2006-05-18 Toyama Prefecture Cell recovery method using magnetic spot array chip
WO2006079998A1 (en) * 2005-01-31 2006-08-03 Koninklijke Philips Electronics N.V. Rapid and sensitive biosensing
JP2006286712A (en) * 2005-03-31 2006-10-19 Asahi Intecc Co Ltd Method and apparatus for magnetizing metal
US20070031819A1 (en) * 2005-04-26 2007-02-08 University Of Washington Microfluidic systems for biological and molecular analysis and methods thereof
US7598199B2 (en) * 2005-05-10 2009-10-06 Massachusetts Institute Of Technology Catalytic nanoparticles for nerve-agent destruction
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
US7615382B2 (en) 2005-11-09 2009-11-10 The Board Of Trustees Of The Leland Stanford Junior University Magnetic sifter
US8460879B2 (en) 2006-02-21 2013-06-11 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
US20090170212A1 (en) * 2006-05-10 2009-07-02 Koninklijke Philips Electronics N.V. Rapid magnetic biosensor
TW200744944A (en) * 2006-05-22 2007-12-16 Audio Pixels Ltd Apparatus for generating pressure and methods of manufacture thereof
SG171693A1 (en) 2006-05-22 2011-06-29 Audio Pixels Ltd Volume and tone control in direct digital speakers
US8457338B2 (en) 2006-05-22 2013-06-04 Audio Pixels Ltd. Apparatus and methods for generating pressure waves
US7807454B2 (en) 2006-10-18 2010-10-05 The Regents Of The University Of California Microfluidic magnetophoretic device and methods for using the same
KR100823684B1 (en) * 2006-12-06 2008-04-21 한국전자통신연구원 Detection method of biological target substance using barcode DNA
US8292083B2 (en) 2007-04-19 2012-10-23 The Charles Stark Draper Laboratory, Inc. Method and apparatus for separating particles, cells, molecules and particulates
EP2150350B1 (en) * 2007-05-24 2012-04-25 The Regents of the University of California Integrated fluidics devices with magnetic sorting
US9551706B2 (en) 2007-06-29 2017-01-24 President And Fellows Of Harvard College Density-based methods for separation of materials, monitoring of solid supported reactions and measuring densities of small liquid volumes and solids
US7837379B2 (en) 2007-08-13 2010-11-23 The Charles Stark Draper Laboratory, Inc. Devices for producing a continuously flowing concentration gradient in laminar flow
EP2178646A1 (en) * 2007-08-23 2010-04-28 Cynvenio Biosystems, LLC Trapping magnetic sorting system for target species
WO2009066290A2 (en) 2007-11-21 2009-05-28 Audio Pixels Ltd. Digital speaker apparatus
US20110127222A1 (en) * 2008-03-19 2011-06-02 Cynvenio Biosystems, Inc. Trapping magnetic cell sorting system
WO2009129415A1 (en) * 2008-04-16 2009-10-22 Cynvenio Biosystems, Llc Magnetic separation system with pre and post processing modules
WO2013019212A1 (en) * 2011-08-02 2013-02-07 Nano3D Biosciences, Inc. Hardware for magnetic 3d culture
WO2010049883A1 (en) * 2008-10-31 2010-05-06 Koninklijke Philips Electronics N.V. Biosensor with multi-chamber cartridge
DE102009005925B4 (en) 2009-01-23 2013-04-04 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Apparatus and method for handling biomolecules
WO2010088761A1 (en) * 2009-02-06 2010-08-12 Maziyar Khorasani Method and apparatus for manipulating and detecting analytes
PT2440941T (en) * 2009-06-10 2017-07-31 Cynvenio Biosystems Inc SHELL FLOW METHODS AND DEVICES
WO2011014607A1 (en) 2009-07-30 2011-02-03 3M Innovative Properties Company Nozzle and method of making same
US8394984B2 (en) * 2010-02-02 2013-03-12 Celanese International Corporation Process for producing an ethyl acetate solvent and co-production of ethanol
US8394985B2 (en) * 2010-02-02 2013-03-12 Celanese International Corporation Process for producing an ester feed stream for esters production and co-production of ethanol
US8575403B2 (en) 2010-05-07 2013-11-05 Celanese International Corporation Hydrolysis of ethyl acetate in ethanol separation process
JP5363663B2 (en) 2010-03-01 2013-12-11 クワンテリクス コーポレーション Method or system for extending the dynamic range in an assay to detect molecules or particles
US8236574B2 (en) 2010-03-01 2012-08-07 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
PT2768241T (en) 2010-03-11 2022-05-17 Audio Pixels Ltd Electrostatic parallel plate actuators whose moving elements are driven only by electrostatic force and methods useful in conjunction therewith
CN101830427B (en) * 2010-04-17 2012-02-22 上海交通大学 Three-dimensional manipulator of diamagnetic particles based on MEMS technology
US9024083B2 (en) 2010-07-09 2015-05-05 Celanese International Corporation Process for the production of ethanol from an acetic acid feed and a recycled ethyl acetate feed
US9254488B2 (en) * 2010-07-09 2016-02-09 Koninklijke Philips N.V. Automated system for selectively processing a sample
US9272970B2 (en) 2010-07-09 2016-03-01 Celanese International Corporation Hydrogenolysis of ethyl acetate in alcohol separation processes
US8664454B2 (en) 2010-07-09 2014-03-04 Celanese International Corporation Process for production of ethanol using a mixed feed using copper containing catalyst
US8704008B2 (en) 2010-07-09 2014-04-22 Celanese International Corporation Process for producing ethanol using a stacked bed reactor
US8710279B2 (en) 2010-07-09 2014-04-29 Celanese International Corporation Hydrogenolysis of ethyl acetate in alcohol separation processes
WO2012019109A1 (en) 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Oscillating immunoassay method and device
EP2601526B1 (en) * 2010-08-05 2016-12-21 Abbott Point Of Care, Inc. Magnetic immunosensor and method of use
US11402375B2 (en) 2010-08-05 2022-08-02 Abbott Point Of Care Inc. Magnetic immunosensor with trench configuration and method of use
WO2012019104A1 (en) 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Immunoassay method and device with magnetically susceptible bead capture
CN102398036B (en) * 2010-09-15 2015-02-25 富士康(昆山)电脑接插件有限公司 Metal cured structure and manufacturing method thereof
WO2012047653A2 (en) * 2010-09-27 2012-04-12 The General Hospital Corporation Self-assembled magnetic arrays
KR20120032255A (en) 2010-09-28 2012-04-05 삼성전자주식회사 Cell separation device and cell separation method using magnetic force
WO2012070042A1 (en) 2010-11-26 2012-05-31 Audio Pixels Ltd. Apparatus and methods for individual addressing and noise reduction in actuator arrays
US9322804B2 (en) 2010-11-29 2016-04-26 President And Fellows Of Harvard College Quality control of diamagnetic materials using magnetic levitation
US9394511B2 (en) * 2010-12-05 2016-07-19 Wenbin Jiang Rapid single cell based parallel biological cell sorter
US9952237B2 (en) * 2011-01-28 2018-04-24 Quanterix Corporation Systems, devices, and methods for ultra-sensitive detection of molecules or particles
US9073816B2 (en) 2011-04-26 2015-07-07 Celanese International Corporation Reducing ethyl acetate concentration in recycle streams for ethanol production processes
US8592635B2 (en) 2011-04-26 2013-11-26 Celanese International Corporation Integrated ethanol production by extracting halides from acetic acid
US8754268B2 (en) 2011-04-26 2014-06-17 Celanese International Corporation Process for removing water from alcohol mixtures
US8895786B2 (en) 2011-08-03 2014-11-25 Celanese International Corporation Processes for increasing alcohol production
US20130188296A1 (en) 2012-01-19 2013-07-25 Ford Global Technologies, Llc Material And Coating For Interconnector Busbars
US8802588B2 (en) 2012-01-23 2014-08-12 Celanese International Corporation Bismuth catalyst composition and process for manufacturing ethanol mixture
EP2856770B1 (en) 2012-05-25 2018-07-04 Audio Pixels Ltd. A system, a method and a computer program product for controlling a set of actuator elements
EP2856769B1 (en) 2012-05-25 2018-07-04 Audio Pixels Ltd. A system, a method and a computer program product for controlling a group of actuator arrays for producing a physical effect
JP5950278B2 (en) * 2012-08-22 2016-07-13 国立大学法人広島大学 Cell separation chip manufacturing method and cell separation chip
US11197374B2 (en) 2012-09-11 2021-12-07 Ferric Inc. Integrated switched inductor power converter having first and second powertrain phases
US11116081B2 (en) 2012-09-11 2021-09-07 Ferric Inc. Laminated magnetic core inductor with magnetic flux closure path parallel to easy axes of magnetization of magnetic layers
US11058001B2 (en) 2012-09-11 2021-07-06 Ferric Inc. Integrated circuit with laminated magnetic core inductor and magnetic flux closure layer
US11064610B2 (en) 2012-09-11 2021-07-13 Ferric Inc. Laminated magnetic core inductor with insulating and interface layers
US10893609B2 (en) 2012-09-11 2021-01-12 Ferric Inc. Integrated circuit with laminated magnetic core inductor including a ferromagnetic alloy
CN103464279B (en) * 2013-09-30 2015-08-19 沈阳隆基电磁科技股份有限公司 The anticorrosion magnetic medium box of a kind of Verticle ring high intensity magnetic separator
KR20150092585A (en) * 2014-02-05 2015-08-13 한국전자통신연구원 DNA data compression Method and Apparatus based on binary image
KR101593545B1 (en) * 2014-05-29 2016-02-26 서울대학교 산학협력단 Sensor for reusable chemical or biological and method of operating the same
US11302469B2 (en) * 2014-06-23 2022-04-12 Ferric Inc. Method for fabricating inductors with deposition-induced magnetically-anisotropic cores
EP3233291A4 (en) 2014-12-15 2018-08-08 The Regents of the University of California Method and device for separation of particles and cells using gradient magnetic ratcheting
CN107533134B (en) 2015-04-15 2021-04-27 音频像素有限公司 Camera, audio sound system, method and system for detecting the position of an object
CN105080408A (en) * 2015-06-17 2015-11-25 电子科技大学 Micro-mixer based on self-assembled grain
US20180257075A1 (en) * 2015-08-10 2018-09-13 Duke University Magnetic single cell arrays for probing cell-drug and cell-cell communication
JP6626303B2 (en) * 2015-09-29 2019-12-25 アイシン精機株式会社 Magnetic modulator
CN105591037A (en) * 2016-03-23 2016-05-18 京东方科技集团股份有限公司 Packaging device
US10189029B2 (en) * 2016-06-30 2019-01-29 United Arab Emirates University Magnetic particle separator
CN109790507A (en) * 2016-07-26 2019-05-21 生物磁学解决方案有限责任公司 Separation simultaneously and the T cell in activating blood product and subsequent stimulation amplification
CN107032284B (en) * 2017-05-04 2018-12-28 北京航空航天大学 A kind of imitative indian cup liquid film fast removal Surface Texture
EP3621607B1 (en) * 2017-05-12 2025-07-23 Universal Sequencing Technology Corporation DBA UST Corporation Method and systems for pulling dna, rna and other biological molecules through nanopores using soft magnetic structures
US20190083909A1 (en) * 2017-09-20 2019-03-21 Neapco Intellectual Property Holdings, Llc Filter system including integrated diagnostics
US12399171B2 (en) 2017-11-09 2025-08-26 Small Machines Microchip and device for quantitative analysis of antigen, and method for quantitative analysis of antigen using same
AU2019243835B2 (en) * 2018-03-26 2025-03-06 LevitasBio, Inc. Magnetic particle isolation device and methods of use
CN108607584B (en) * 2018-05-08 2021-02-09 重庆大学 Magnetic composite multi-bismuth visible-light-driven photocatalyst Bi24O31Br10-SrFe12O19Preparation method of (1)
EP3833479A1 (en) * 2018-08-06 2021-06-16 Corning Incorporated Patterned microfluidic devices and methods for manufacturing the same
CN109746064B (en) * 2019-01-28 2021-10-15 武汉纺织大学 A gradient magnetic field microfluidic chip
EP3999847A4 (en) * 2019-07-15 2023-10-18 Universal Sequencing Technology Corporation Sequencing of biopolymers by motion-controlled electron tunneling
CN110639629A (en) * 2019-09-12 2020-01-03 山东大学 A nano-pillar array microfluidic chip and its detection method
CN114100704B (en) * 2020-09-22 2022-12-06 中国科学院深圳先进技术研究院 Magnetic separation micro-fluidic chip and manufacturing method thereof
EP3978119A1 (en) 2020-09-30 2022-04-06 Levitas, Inc. Particle separator system, materials, and methods of use
US12322695B2 (en) 2020-12-01 2025-06-03 Ferric Inc. Magnetic core with hard ferromagnetic biasing layers and structures containing same
CN114653268B (en) * 2022-03-21 2023-03-24 哈尔滨工业大学 Pneumatic micro-fluidic sample processing module of microballon vibrating
US12125713B2 (en) 2022-03-22 2024-10-22 Ferric Inc. Method for manufacturing ferromagnetic-dielectric composite material
US20250083146A1 (en) * 2022-03-22 2025-03-13 The Penn State Research Foundation Nucleic acid testing in a portable device
CN114952785B (en) * 2022-05-30 2023-03-10 江南大学 An independent magnetic drive system for a magnetic micro-nano robot

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU530410B2 (en) * 1978-02-21 1983-07-14 Sintef Preparing aqueous emulsions
US4421660A (en) * 1980-12-15 1983-12-20 The Dow Chemical Company Colloidal size hydrophobic polymers particulate having discrete particles of an inorganic material dispersed therein
JPS5876435A (en) * 1981-10-30 1983-05-09 Japan Synthetic Rubber Co Ltd Polymeric particle
NO155316C (en) * 1982-04-23 1987-03-11 Sintef PROCEDURE FOR MAKING MAGNETIC POLYMER PARTICLES.
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
GB2191110B (en) * 1986-06-06 1989-12-06 Plessey Co Plc Chromatographic separation device
US4770183A (en) * 1986-07-03 1988-09-13 Advanced Magnetics Incorporated Biologically degradable superparamagnetic particles for use as nuclear magnetic resonance imaging agents
US5395688A (en) * 1987-10-26 1995-03-07 Baxter Diagnostics Inc. Magnetically responsive fluorescent polymer particles
US5091206A (en) * 1987-10-26 1992-02-25 Baxter Diagnostics Inc. Process for producing magnetically responsive polymer particles and application thereof
US4965007A (en) * 1988-05-10 1990-10-23 Eastman Kodak Company Encapsulated superparamagnetic particles
US4908112A (en) * 1988-06-16 1990-03-13 E. I. Du Pont De Nemours & Co. Silicon semiconductor wafer for analyzing micronic biological samples
US5132012A (en) * 1988-06-24 1992-07-21 Hitachi, Ltd. Liquid chromatograph
US5232789A (en) * 1989-03-09 1993-08-03 Mtu Motoren- Und Turbinen-Union Muenchen Gmbh Structural component with a protective coating having a nickel or cobalt basis and method for making such a coating
FR2645160B1 (en) * 1989-03-31 1992-10-02 Rhone Poulenc Chimie
US5126022A (en) * 1990-02-28 1992-06-30 Soane Tecnologies, Inc. Method and device for moving molecules by the application of a plurality of electrical fields
US5750015A (en) * 1990-02-28 1998-05-12 Soane Biosciences Method and device for moving molecules by the application of a plurality of electrical fields
GB2244135B (en) * 1990-05-04 1994-07-13 Gen Electric Co Plc Sensor devices
US5318797A (en) * 1990-06-20 1994-06-07 Clarkson University Coated particles, hollow particles, and process for manufacturing the same
US5580523A (en) * 1994-04-01 1996-12-03 Bard; Allen J. Integrated chemical synthesizers
US6001229A (en) * 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
US5571410A (en) * 1994-10-19 1996-11-05 Hewlett Packard Company Fully integrated miniaturized planar liquid sample handling and analysis device
US5655665A (en) * 1994-12-09 1997-08-12 Georgia Tech Research Corporation Fully integrated micromachined magnetic particle manipulator and separator
US5834121A (en) * 1996-01-16 1998-11-10 Solid Phase Sciences Corp. Composite magnetic beads
US5885470A (en) * 1997-04-14 1999-03-23 Caliper Technologies Corporation Controlled fluid transport in microfabricated polymeric substrates
AU3374597A (en) * 1996-06-07 1998-01-05 Immunivest Corporation Magnetic separation employing external and internal gradients
US5779907A (en) * 1996-12-06 1998-07-14 Systems Research Laboratories, Inc. Magnetic microplate separator
ATE251306T1 (en) * 1997-03-25 2003-10-15 Immunivest Corp APPARATUS AND METHODS FOR CAPTURE AND ANALYZING PARTICLE UNITS
US6036857A (en) * 1998-02-20 2000-03-14 Florida State University Research Foundation, Inc. Apparatus for continuous magnetic separation of components from a mixture
US6672458B2 (en) * 2000-05-19 2004-01-06 Becton, Dickinson And Company System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample
US6514416B1 (en) * 2001-05-07 2003-02-04 Dexter Magnetic Technologies, Inc. Method and apparatus for magnetic separation of particles

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