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AU2001261443A1 - Pituitary tumor transforming gene (pttg) carboxy-terminal peptides and methods of use thereof to inhibit neoplastic cellular proliferation and/or transformation - Google Patents

Pituitary tumor transforming gene (pttg) carboxy-terminal peptides and methods of use thereof to inhibit neoplastic cellular proliferation and/or transformation

Info

Publication number
AU2001261443A1
AU2001261443A1 AU2001261443A AU6144301A AU2001261443A1 AU 2001261443 A1 AU2001261443 A1 AU 2001261443A1 AU 2001261443 A AU2001261443 A AU 2001261443A AU 6144301 A AU6144301 A AU 6144301A AU 2001261443 A1 AU2001261443 A1 AU 2001261443A1
Authority
AU
Australia
Prior art keywords
pttg
carboxy
transformation
methods
cellular proliferation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001261443A
Inventor
_Anthony P. Heaney
Gregory A. Horwitz
Shlomo Melmed
Xun Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cedars Sinai Medical Center
Original Assignee
Cedars Sinai Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/569,956 external-priority patent/US6894031B1/en
Priority claimed from US09/730,469 external-priority patent/US20030018001A1/en
Application filed by Cedars Sinai Medical Center filed Critical Cedars Sinai Medical Center
Publication of AU2001261443A1 publication Critical patent/AU2001261443A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
AU2001261443A 2000-05-12 2001-05-12 Pituitary tumor transforming gene (pttg) carboxy-terminal peptides and methods of use thereof to inhibit neoplastic cellular proliferation and/or transformation Abandoned AU2001261443A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US09/569,956 US6894031B1 (en) 1996-11-21 2000-05-12 Pituitary tumor transforming gene (PTTG) carboxy-terminal peptides and methods of use thereof to inhibit neoplastic cellular proliferation and/or transformation
US09569956 2000-05-12
US68791100A 2000-10-13 2000-10-13
US09687911 2000-10-13
US09/730,469 US20030018001A1 (en) 1996-11-21 2000-12-04 Methods of using pituitary tumor transforming gene (PTTG) carboxy-terminal peptides to inhibit neoplastic cellular proliferation and/or transformation of breast and ovarian cells
US09730469 2000-12-04
US09777422 2001-02-05
US09/777,422 US20020147162A1 (en) 1996-11-21 2001-02-05 Methods of modulating angiogenesis by regulating the expression of pituitary tumor transforming gene (PTTG)
PCT/US2001/015254 WO2001087934A2 (en) 2000-05-12 2001-05-12 Treatment of neoplasia/transformation using a pituitary tumor transforming gene carboxy terminal peptides

Publications (1)

Publication Number Publication Date
AU2001261443A1 true AU2001261443A1 (en) 2001-11-26

Family

ID=27504884

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001263059A Abandoned AU2001263059A1 (en) 2000-05-12 2001-05-12 Method of regulating biological activity of pituitary tumor transforming gene (pttg)1 using pttg2
AU2001261443A Abandoned AU2001261443A1 (en) 2000-05-12 2001-05-12 Pituitary tumor transforming gene (pttg) carboxy-terminal peptides and methods of use thereof to inhibit neoplastic cellular proliferation and/or transformation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU2001263059A Abandoned AU2001263059A1 (en) 2000-05-12 2001-05-12 Method of regulating biological activity of pituitary tumor transforming gene (pttg)1 using pttg2

Country Status (5)

Country Link
US (1) US20020147162A1 (en)
EP (1) EP1280905A2 (en)
JP (2) JP2003535612A (en)
AU (2) AU2001263059A1 (en)
WO (1) WO2001087934A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10200410A1 (en) * 2002-01-08 2003-07-24 Marc Roller New antisense oligonucleotide, useful for treatment of tumors, inhibits translation of mRNA from the pituitary-tumor transforming gene-1
KR100627377B1 (en) 2005-03-04 2006-09-25 한국생명공학연구원 Gene therapy of cancer using a small interfering RNA and a vector expressing the same, which may block the synthesis of pituitary tumor-transforming gene 1 protein

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455305B1 (en) * 1996-11-21 2002-09-24 Cedars-Sinai Medical Center Pituitary-tumor-transforming-genes, and related products

Also Published As

Publication number Publication date
WO2001087934A2 (en) 2001-11-22
WO2001087934A3 (en) 2002-05-30
EP1280905A2 (en) 2003-02-05
JP2004526403A (en) 2004-09-02
AU2001263059A1 (en) 2001-11-26
JP2003535612A (en) 2003-12-02
US20020147162A1 (en) 2002-10-10

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