AU2001255090A1 - Cdk inhibitors having 3-hydroxychromen-4-one structure - Google Patents
Cdk inhibitors having 3-hydroxychromen-4-one structureInfo
- Publication number
- AU2001255090A1 AU2001255090A1 AU2001255090A AU5509001A AU2001255090A1 AU 2001255090 A1 AU2001255090 A1 AU 2001255090A1 AU 2001255090 A AU2001255090 A AU 2001255090A AU 5509001 A AU5509001 A AU 5509001A AU 2001255090 A1 AU2001255090 A1 AU 2001255090A1
- Authority
- AU
- Australia
- Prior art keywords
- hydroxychromen
- cdk inhibitors
- cdk
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- DCMHKQKYWBSFKE-UHFFFAOYSA-N 3-hydroxychromen-4-one Chemical group C1=CC=C2C(=O)C(O)=COC2=C1 DCMHKQKYWBSFKE-UHFFFAOYSA-N 0.000 title 1
- 229940043378 cyclin-dependent kinase inhibitor Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR0023705 | 2000-05-03 | ||
| KR1020000023705A KR20010103188A (en) | 2000-05-03 | 2000-05-03 | CDK inhibitors having 3-hydroxychromen-4-one structure |
| KR10-2000-0054573A KR100399364B1 (en) | 2000-09-18 | 2000-09-18 | 3-Hydroxy-6-aminochromene-4-on derivatives useful as cyclin dependendent kinase inhibitors |
| KR0054577 | 2000-09-18 | ||
| KR0054573 | 2000-09-18 | ||
| KR10-2000-0054577A KR100392468B1 (en) | 2000-09-18 | 2000-09-18 | 3-Hydroxychromene-4-on derivatives useful as cyclin dependendent kinase inhibitors |
| PCT/KR2001/000725 WO2001083469A1 (en) | 2000-05-03 | 2001-05-03 | Cdk inhibitors having 3-hydroxychromen-4-one structure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001255090A1 true AU2001255090A1 (en) | 2001-11-12 |
Family
ID=27350225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001255090A Abandoned AU2001255090A1 (en) | 2000-05-03 | 2001-05-03 | Cdk inhibitors having 3-hydroxychromen-4-one structure |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6683095B2 (en) |
| EP (1) | EP1280789A1 (en) |
| JP (1) | JP2003531899A (en) |
| CN (1) | CN1433410A (en) |
| AU (1) | AU2001255090A1 (en) |
| CA (1) | CA2407796A1 (en) |
| WO (1) | WO2001083469A1 (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100399364B1 (en) * | 2000-09-18 | 2003-09-26 | 주식회사 엘지생명과학 | 3-Hydroxy-6-aminochromene-4-on derivatives useful as cyclin dependendent kinase inhibitors |
| US20050154046A1 (en) * | 2004-01-12 | 2005-07-14 | Longgui Wang | Methods of treating an inflammatory-related disease |
| CN100381437C (en) * | 2002-04-17 | 2008-04-16 | 赛特凯恩蒂克公司 | Compounds, compositions and methods |
| AU2003245935A1 (en) * | 2002-06-13 | 2003-12-31 | Novuspharma S.P.A. | Derivatives of chromen-2-one as inhibitors of vegf production in mammalian cells |
| US7884127B2 (en) | 2002-07-08 | 2011-02-08 | Pirimal Life Sciences Ltd. | Inhibitors of cyclin dependent kinases and their use |
| US7915301B2 (en) | 2002-07-08 | 2011-03-29 | Piramal Life Science Limited | Inhibitors of cyclin dependent kinases and their use |
| US7271193B2 (en) | 2002-07-08 | 2007-09-18 | Nicholas Piramal India, Ltd. | Inhibitors of cyclin-dependent kinases and their use |
| TWI331034B (en) * | 2002-07-08 | 2010-10-01 | Piramal Life Sciences Ltd | Inhibitors of cyclin-dependent kinases and their use |
| SE0400759D0 (en) * | 2004-03-23 | 2004-03-23 | Astrazeneca Ab | Novel amination process |
| CA2658215C (en) * | 2006-07-07 | 2013-08-27 | Piramal Life Sciences Limited | An enantioselective synthesis of pyrrolidines-substituted flavones |
| GB201017315D0 (en) | 2010-10-13 | 2010-11-24 | Antoxis Ltd | Compound |
| EP2742033B1 (en) * | 2011-08-11 | 2018-09-19 | Armaron Bio Pty Ltd | Flavonoid compounds, and methods of use thereof |
| TWI839690B (en) | 2013-07-12 | 2024-04-21 | 印度商皮拉馬爾企業有限公司 | Use of a pharmaceutical combination for the treatment of melanoma |
| WO2018073687A1 (en) | 2016-10-20 | 2018-04-26 | Pfizer Inc. | Anti-proliferative agents for treating pah |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS632925A (en) * | 1986-06-23 | 1988-01-07 | Nippon Kayaku Co Ltd | C-kinase inhibitor and anti-tumor agent |
| US5911995A (en) * | 1994-08-19 | 1999-06-15 | Regents Of The University Of Minnesota | EGF-genistein conjugates for the treatment of cancer |
| GB9621757D0 (en) | 1996-10-18 | 1996-12-11 | Ciba Geigy Ag | Phenyl-substituted bicyclic heterocyclyl derivatives and their use |
| KR20010071836A (en) | 1998-09-01 | 2001-07-31 | 성재갑 | Novel Cyclin Dependent Kinase inhibitors having flavone structure |
-
2001
- 2001-05-03 EP EP01928232A patent/EP1280789A1/en not_active Withdrawn
- 2001-05-03 WO PCT/KR2001/000725 patent/WO2001083469A1/en not_active Ceased
- 2001-05-03 AU AU2001255090A patent/AU2001255090A1/en not_active Abandoned
- 2001-05-03 CN CN01809823A patent/CN1433410A/en active Pending
- 2001-05-03 US US10/275,066 patent/US6683095B2/en not_active Expired - Fee Related
- 2001-05-03 CA CA002407796A patent/CA2407796A1/en not_active Abandoned
- 2001-05-03 JP JP2001580897A patent/JP2003531899A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1433410A (en) | 2003-07-30 |
| CA2407796A1 (en) | 2001-11-08 |
| EP1280789A1 (en) | 2003-02-05 |
| JP2003531899A (en) | 2003-10-28 |
| US20030125356A1 (en) | 2003-07-03 |
| WO2001083469A1 (en) | 2001-11-08 |
| US6683095B2 (en) | 2004-01-27 |
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