AU2001246478A1 - Farnesyl protein transferase inhibitor combinations with taxane compounds - Google Patents
Farnesyl protein transferase inhibitor combinations with taxane compoundsInfo
- Publication number
- AU2001246478A1 AU2001246478A1 AU2001246478A AU4647801A AU2001246478A1 AU 2001246478 A1 AU2001246478 A1 AU 2001246478A1 AU 2001246478 A AU2001246478 A AU 2001246478A AU 4647801 A AU4647801 A AU 4647801A AU 2001246478 A1 AU2001246478 A1 AU 2001246478A1
- Authority
- AU
- Australia
- Prior art keywords
- protein transferase
- transferase inhibitor
- farnesyl protein
- taxane compounds
- inhibitor combinations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000003528 protein farnesyltransferase inhibitor Substances 0.000 title 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00200689 | 2000-02-29 | ||
| EP00200689 | 2000-02-29 | ||
| PCT/EP2001/002170 WO2001064199A2 (en) | 2000-02-29 | 2001-02-26 | Farnesyl protein transferase inhibitor combinations with taxane compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001246478A1 true AU2001246478A1 (en) | 2001-09-12 |
Family
ID=8171108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001246478A Abandoned AU2001246478A1 (en) | 2000-02-29 | 2001-02-26 | Farnesyl protein transferase inhibitor combinations with taxane compounds |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20030181473A1 (en) |
| EP (1) | EP1265611A2 (en) |
| JP (1) | JP2003525239A (en) |
| AU (1) | AU2001246478A1 (en) |
| CA (1) | CA2397425A1 (en) |
| WO (1) | WO2001064199A2 (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003047697A2 (en) * | 2001-11-30 | 2003-06-12 | Schering Corporation | Use of an farsenyl protein tranferase inhibitor in combination with other antineoplastic agents for the manufacture of a medicament against cancer |
| EP1453513A1 (en) * | 2001-12-03 | 2004-09-08 | Schering Corporation | Use of fpt inhibitors and at least two antineoplastic agents in the treatment of cancer |
| US7557107B2 (en) | 2003-08-07 | 2009-07-07 | Schering Coporation | Farnesyl protein transferase inhibitors as antitumor agents |
| SV2005001973A (en) | 2003-12-12 | 2005-11-04 | Wyeth Corp | USEFUL KINOLINES IN THE TREATMENT OF CARDIOVASCULAR DISEASES REF. WYTH0090-504 (AM101500) |
| US20050272068A1 (en) * | 2004-03-18 | 2005-12-08 | The Brigham And Women's Hospital, Inc. | UCH-L1 expression and cancer therapy |
| US20060194821A1 (en) * | 2005-02-18 | 2006-08-31 | The Brigham And Women's Hospital, Inc. | Compounds inhibiting the aggregation of superoxide dismutase-1 |
| WO2007075923A2 (en) | 2005-12-23 | 2007-07-05 | Link Medicine Corporation | Treatment of synucleinopathies |
| WO2009151683A2 (en) | 2008-03-12 | 2009-12-17 | Link Medicine Corporation | Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications |
| WO2010057006A1 (en) | 2008-11-13 | 2010-05-20 | Link Medicine Corporation | Azaquinolinone derivatives and uses thereof |
| CA2888485C (en) | 2012-10-16 | 2021-01-26 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of ror.gamma.t |
| AU2013331496B2 (en) | 2012-10-16 | 2017-07-27 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of ROR-gamma-t |
| BR112015008515A2 (en) | 2012-10-16 | 2017-07-04 | Janssen Pharmaceutica Nv | heteroaryl-linked quinolinyl ror t modulators |
| EP3057422B1 (en) | 2013-10-15 | 2019-05-15 | Janssen Pharmaceutica NV | Quinolinyl modulators of ror(gamma)t |
| JP6423423B2 (en) | 2013-10-15 | 2018-11-14 | ヤンセン ファーマシューティカ エヌ．ベー． | Rorγt alkyl-linked quinolinyl modulator |
| US9403816B2 (en) | 2013-10-15 | 2016-08-02 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of RORγt |
| US9221804B2 (en) | 2013-10-15 | 2015-12-29 | Janssen Pharmaceutica Nv | Secondary alcohol quinolinyl modulators of RORγt |
| US10555941B2 (en) | 2013-10-15 | 2020-02-11 | Janssen Pharmaceutica Nv | Alkyl linked quinolinyl modulators of RORγt |
| US9328095B2 (en) | 2013-10-15 | 2016-05-03 | Janssen Pharmaceutica Nv | Heteroaryl linked quinolinyl modulators of RORgammat |
| US9284308B2 (en) | 2013-10-15 | 2016-03-15 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of RORγt |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601676B1 (en) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | PROCESS FOR THE PREPARATION OF TAXOL AND DESACETYL-10 TAXOL |
| FR2601675B1 (en) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| MX9102128A (en) * | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | DERIVATIVES OF TAXANE, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM |
| TW349948B (en) * | 1995-10-31 | 1999-01-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 2-quinolone derivatives |
| BR9610745A (en) * | 1995-12-08 | 1999-07-13 | Janssen Pharmaceutica Nv | (Imidazol-5-yl) methyl-2-quinolinone derivatives inhibiting farnesyl protein transferase |
| US5919815A (en) * | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
| TW591030B (en) * | 1997-03-10 | 2004-06-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles |
| NZ336233A (en) * | 1997-04-25 | 2001-01-26 | Janssen Pharmaceutica Nv | Phenyl substituted quinazolines on 4-position and 2-quinazolinone moiety bearing a carbon or nitrogen-linked imidazolyl moiety |
| US6096757A (en) * | 1998-12-21 | 2000-08-01 | Schering Corporation | Method for treating proliferative diseases |
| WO1999065494A1 (en) * | 1998-06-15 | 1999-12-23 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
| US6013646A (en) * | 1998-07-02 | 2000-01-11 | Bayer Corporation | Indolocarbazole derivatives useful for the treatment of neurodegenerative diseases and cancer |
| ID29241A (en) * | 1998-12-23 | 2001-08-16 | Janssen Pharmaceutica Nv | TERANELASI KINOLIN DISTRICTS-1,2 |
-
2001
- 2001-02-26 AU AU2001246478A patent/AU2001246478A1/en not_active Abandoned
- 2001-02-26 US US10/220,396 patent/US20030181473A1/en not_active Abandoned
- 2001-02-26 CA CA002397425A patent/CA2397425A1/en not_active Abandoned
- 2001-02-26 WO PCT/EP2001/002170 patent/WO2001064199A2/en not_active Ceased
- 2001-02-26 EP EP01919348A patent/EP1265611A2/en not_active Withdrawn
- 2001-02-26 JP JP2001563096A patent/JP2003525239A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003525239A (en) | 2003-08-26 |
| WO2001064199A3 (en) | 2001-12-27 |
| EP1265611A2 (en) | 2002-12-18 |
| US20030181473A1 (en) | 2003-09-25 |
| WO2001064199A2 (en) | 2001-09-07 |
| CA2397425A1 (en) | 2001-09-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2001240658A1 (en) | Farnesyl protein transferase inhibitor combinations with camptothecin compounds | |
| AU2001246477A1 (en) | Farnesyl protein transferase inhibitor combinations with platinum compounds | |
| AU2001254672A1 (en) | Farnesyl protein transferase inhibitor combinations with an her2 antibody | |
| AU2001246478A1 (en) | Farnesyl protein transferase inhibitor combinations with taxane compounds | |
| AU2001258771A1 (en) | -secretase inhibitors | |
| AU2001234484A1 (en) | Amide compounds for inhibiting protein kinases | |
| AU2001237041A1 (en) | Kinase inhibitors | |
| AU2001296961A1 (en) | 17-beta-hydroxysteroid dehydrogenase-ii inhibitors | |
| AU2001252147A1 (en) | Farnesyl protein transferase inhibitor combinations | |
| AU2001235496A1 (en) | Farnesyl protein transferase inhibitor combinations with anti-tumor alkylating agents | |
| AU2001244166A1 (en) | Farnesyl protein transferase inhibitor combinations with further anti-cancer agents | |
| AU2001230336A1 (en) | Fixture | |
| AU2001239275A1 (en) | Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives | |
| AU2001247882A1 (en) | Tricyclic protein kinase inhibitors | |
| AU2001253197A1 (en) | Non-imidazole benzodiazepine inhibitors of farnesyl protein transferase | |
| ZA200301545B (en) | Tricyclic antitumor compounds being farnesyl protein transferase inhibitors. | |
| AU2001250321A1 (en) | Homogentisate phytyl transferase | |
| AU2001244167A1 (en) | Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives | |
| AU2001272651A1 (en) | Valves | |
| AU2001242434A1 (en) | Farnesyl protein transferase inhibitor combinations with vinca alkaloids | |
| DK1339695T3 (en) | Farnesyl transferase inhibitors | |
| AU3724701A (en) | Family 5 xyloglucanases | |
| AU2435199A (en) | Farnesyl transferase inhibitors | |
| AU2001255408A1 (en) | Tetrahydro-azepinone derivatives as thrombin inhibitors | |
| PL355887A1 (en) | Farnesyl transferase inhibitors |