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AU2001240885A1 - Use of glucosylceramide synthesis inhibitors in brain cancer therapy - Google Patents

Use of glucosylceramide synthesis inhibitors in brain cancer therapy

Info

Publication number
AU2001240885A1
AU2001240885A1 AU2001240885A AU4088501A AU2001240885A1 AU 2001240885 A1 AU2001240885 A1 AU 2001240885A1 AU 2001240885 A AU2001240885 A AU 2001240885A AU 4088501 A AU4088501 A AU 4088501A AU 2001240885 A1 AU2001240885 A1 AU 2001240885A1
Authority
AU
Australia
Prior art keywords
cancer therapy
brain cancer
synthesis inhibitors
glucosylceramide synthesis
glucosylceramide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001240885A
Inventor
Frances M Platt
Thomas N. Seyfried
Paul David Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Oxford
Oxford Glycosciences UK Ltd
Original Assignee
CHANCELLOR MASTERS
University of Oxford
Oxford Glycosciences UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHANCELLOR MASTERS, University of Oxford, Oxford Glycosciences UK Ltd filed Critical CHANCELLOR MASTERS
Publication of AU2001240885A1 publication Critical patent/AU2001240885A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001240885A 2000-03-17 2001-03-19 Use of glucosylceramide synthesis inhibitors in brain cancer therapy Abandoned AU2001240885A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0006539.1A GB0006539D0 (en) 2000-03-17 2000-03-17 Therapies
GB0006539 2000-03-17
PCT/GB2001/001189 WO2001068093A1 (en) 2000-03-17 2001-03-19 Use of glucosylceramide synthesis inhibitors in brain cancertherapy

Publications (1)

Publication Number Publication Date
AU2001240885A1 true AU2001240885A1 (en) 2001-09-24

Family

ID=9887886

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001240885A Abandoned AU2001240885A1 (en) 2000-03-17 2001-03-19 Use of glucosylceramide synthesis inhibitors in brain cancer therapy

Country Status (6)

Country Link
US (1) US20030069200A1 (en)
EP (1) EP1263436A1 (en)
JP (1) JP2003534244A (en)
AU (1) AU2001240885A1 (en)
GB (1) GB0006539D0 (en)
WO (1) WO2001068093A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005123055A2 (en) * 2004-06-14 2005-12-29 Musc Foundation For Research Development Methods for treating inflammatory disorders
US20070248591A1 (en) * 2004-09-08 2007-10-25 Takeda Pharmaceutical Company Limited Preventive/Therapeutic Drug for Arteriosclerosis
WO2007062073A2 (en) * 2005-11-23 2007-05-31 Trustees Of Boston College Models of metastatic tumors
GB0614098D0 (en) * 2006-07-15 2006-08-23 Mnl Pharma Ltd Immune response variegation with imino sugars

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837237A (en) * 1985-07-09 1989-06-06 Fred Hutchinson Cancer Research Center Therapy using glucosidase processing inhibitors
EP0536402A4 (en) * 1990-06-29 1993-05-12 Nippon Shinyaku Company, Limited Piperidine derivative
US5399567A (en) * 1993-05-13 1995-03-21 Monsanto Company Method of treating cholera
ZA9810210B (en) * 1997-11-10 1999-07-14 Searle & Co Use of alkylated iminosugars to treat multidrug resistance.
CA2335941C (en) * 1998-06-29 2011-03-22 Barry James Maurer Treatment of hyperproliferative disorders
WO2000056334A1 (en) * 1999-03-19 2000-09-28 The Trustees Of Boston College Use of imino sugars for anti-tumor therapy
GB9909066D0 (en) * 1999-04-20 1999-06-16 Oxford Glycosciences Uk Ltd Therapies

Also Published As

Publication number Publication date
GB0006539D0 (en) 2000-05-10
JP2003534244A (en) 2003-11-18
WO2001068093A1 (en) 2001-09-20
US20030069200A1 (en) 2003-04-10
EP1263436A1 (en) 2002-12-11

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