AU2065697A - Iron complexes of nitrogen-containing macrocyclic ligands effective as cataly sts for dismutating superoxide - Google Patents

Iron complexes of nitrogen-containing macrocyclic ligands effective as cataly sts for dismutating superoxide

Info

Publication number: AU2065697A
Authority: AU; Australia
Prior art keywords: alkyl; aryl; acid; groups; solution
Prior art date: 1996-03-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU20656/97A

Other languages

English (en)

Inventor

Dennis P. Riley

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Monsanto Co

Original Assignee

GD Searle LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-13

Filing date

1997-03-11

Publication date

1997-10-01

1997-03-11 Application filed by GD Searle LLC filed Critical GD Searle LLC

1997-10-01 Publication of AU2065697A publication Critical patent/AU2065697A/en

Status Abandoned legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
- C07F15/025—Iron compounds without a metal-carbon linkage
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Microbiology (AREA)
Urology & Nephrology (AREA)
Analytical Chemistry (AREA)
Biotechnology (AREA)
Immunology (AREA)
Physics & Mathematics (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Vascular Medicine (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Enzymes And Modification Thereof (AREA)

AU20656/97A 1996-03-13 1997-03-11 Iron complexes of nitrogen-containing macrocyclic ligands effective as cataly sts for dismutating superoxide Abandoned AU2065697A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US61471096A	1996-03-13	1996-03-13
US08614710		1996-03-13
PCT/US1997/003348 WO1997033588A1 (en)	1996-03-13	1997-03-11	Iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide

Publications (1)

Publication Number	Publication Date
AU2065697A true AU2065697A (en)	1997-10-01

Family

ID=24462404

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU20656/97A Abandoned AU2065697A (en)	1996-03-13	1997-03-11	Iron complexes of nitrogen-containing macrocyclic ligands effective as cataly sts for dismutating superoxide

Country Status (10)

Country	Link
EP (1)	EP0888115A1 (pt)
JP (1)	JP2000507929A (pt)
KR (1)	KR19990087783A (pt)
AU (1)	AU2065697A (pt)
BR (1)	BR9707978A (pt)
CA (1)	CA2248964A1 (pt)
CZ (1)	CZ277698A3 (pt)
IL (1)	IL125993A0 (pt)
NO (1)	NO984165L (pt)
WO (1)	WO1997033588A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6127356A (en)	1993-10-15	2000-10-03	Duke University	Oxidant scavengers
EP1045851B1 (en)	1997-11-03	2003-04-23	Duke University	Substituted porphyrins
EP1616869B1 (en)	1999-01-25	2012-04-04	National Jewish Health	Substituted porphyrins and their therapeutic use
JP2003500174A (ja)	1999-05-27	2003-01-07	フアルマシア・コーポレーシヨン	スーパーオキシド・ジスムターゼ模倣体で修飾された生体材料
ATE464061T1 (de) *	2001-01-05	2010-04-15	Metaphore Pharmaceuticals Inc	Zusammensetzungen und verfahren zur erhöhung der zytokin-aktivität und zur behandlung der hypotension assoziiert mit der verabreichung von zytokinen
WO2002058686A2 (en) *	2001-01-26	2002-08-01	Metaphore Pharmaceuticals, Inc.	Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes
WO2002098431A1 (en)	2001-06-01	2002-12-12	National Jewish Medical And Research Center	Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
WO2003103680A1 (en)	2002-06-07	2003-12-18	Duke University	Substituted porphyrins
US8468189B2 (en)	2006-11-08	2013-06-18	Okinawa Institute Of Science And Technology Promotion Corporation	Iterated variational regularization combined with componentwise regularization
ES2600469T3 (es)	2008-05-23	2017-02-09	National Jewish Health	Un compuesto para su uso en el tratamiento de lesiones asociadas con la exposición al gas fosgeno o al gas de cloro

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0524161A1 (en) *	1991-07-19	1993-01-20	Monsanto Company	Manganese complexes of nitrogen containing macrocyclic ligands effective as catalysts for dismutating superoxide
BR9507477A (pt) *	1994-04-22	1997-09-16	Searle & Co	Métodos de análise de imagem de diagnóstico usando complexos metálicos de ligantes macrocíclicos contendo nitrogênio
US6525041B1 (en) *	1995-06-06	2003-02-25	Pharmacia Corporation	Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide

1997
- 1997-03-11 BR BR9707978A patent/BR9707978A/pt not_active Application Discontinuation
- 1997-03-11 CZ CZ982776A patent/CZ277698A3/cs unknown
- 1997-03-11 WO PCT/US1997/003348 patent/WO1997033588A1/en not_active Ceased
- 1997-03-11 EP EP97908848A patent/EP0888115A1/en not_active Withdrawn
- 1997-03-11 JP JP9532095A patent/JP2000507929A/ja active Pending
- 1997-03-11 CA CA002248964A patent/CA2248964A1/en not_active Abandoned
- 1997-03-11 AU AU20656/97A patent/AU2065697A/en not_active Abandoned
- 1997-03-11 KR KR1019980707264A patent/KR19990087783A/ko not_active Withdrawn
- 1997-03-11 IL IL12599397A patent/IL125993A0/xx unknown
1998
- 1998-09-10 NO NO984165A patent/NO984165L/no unknown

Also Published As

Publication number	Publication date
NO984165D0 (no)	1998-09-10
IL125993A0 (en)	1999-04-11
EP0888115A1 (en)	1999-01-07
NO984165L (no)	1998-11-10
WO1997033588A1 (en)	1997-09-18
CA2248964A1 (en)	1997-09-18
CZ277698A3 (cs)	1999-02-17
KR19990087783A (ko)	1999-12-27
BR9707978A (pt)	1999-07-27
JP2000507929A (ja)	2000-06-27

Publication	Publication Date	Title
US6204259B1 (en)	2001-03-20	Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
US6525041B1 (en)	2003-02-25	Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
KR0145953B1 (ko)	1998-08-17	슈퍼옥사이드의 불균화촉매로서 효과적인 질소를 포함하는 마크로사이클 릭리간드의 망간착물
AU706642B2 (en)	1999-06-17	Diagnostic image analysis with metal complexes
AU700958B2 (en)	1999-01-14	Bioconjugates of manganese complexes and their application as catalysts
US5721361A (en)	1998-02-24	Process for preparing substituted polyazamacrocycles
EP0891338A1 (en)	1999-01-20	Bioconjugates of manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
AU2065697A (en)	1997-10-01	Iron complexes of nitrogen-containing macrocyclic ligands effective as cataly sts for dismutating superoxide
WO1997033588A9 (en)	1997-11-06	Iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
MXPA98007449A (en)	1999-04-06	Complexes with iron of macrocyclic ligands containing nitrogen, effective as catalysts to dismute superox
MXPA98001322A (en)	1998-10-23	Bioconjugados de complejos de manganeso de ligandos macrociclicos containing nitrogen, effective as catalysts to dismute superox
KR0154346B1 (ko)	1998-12-01	슈퍼옥사이드의 불균환 촉매로서 효과적인 질소를 포함하는 마크로사이클릭 리간드의 망간 착물

Legal Events

Date	Code	Title	Description
2001-04-05	MK5	Application lapsed section 142(2)(e) - patent request and compl. specification not accepted