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AU2042301A - 1-aminoalkyl-1H-indoles for treating glaucoma - Google Patents

1-aminoalkyl-1H-indoles for treating glaucoma

Info

Publication number
AU2042301A
AU2042301A AU20423/01A AU2042301A AU2042301A AU 2042301 A AU2042301 A AU 2042301A AU 20423/01 A AU20423/01 A AU 20423/01A AU 2042301 A AU2042301 A AU 2042301A AU 2042301 A AU2042301 A AU 2042301A
Authority
AU
Australia
Prior art keywords
indoles
aminoalkyl
treating glaucoma
glaucoma
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU20423/01A
Inventor
Hwang-Hsing Chen
Anura P. Dantanarayana
Jesse A. May
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
HWANG HSING CHEN
Alcon Universal Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HWANG HSING CHEN, Alcon Universal Ltd filed Critical HWANG HSING CHEN
Publication of AU2042301A publication Critical patent/AU2042301A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU20423/01A 1999-12-03 2000-11-14 1-aminoalkyl-1H-indoles for treating glaucoma Abandoned AU2042301A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16883299P 1999-12-03 1999-12-03
US60168832 1999-12-03
US19020700P 2000-03-17 2000-03-17
US60190207 2000-03-17
PCT/US2000/031248 WO2001040183A1 (en) 1999-12-03 2000-11-14 1-aminoalkyl-1h-indoles for treating glaucoma

Publications (1)

Publication Number Publication Date
AU2042301A true AU2042301A (en) 2001-06-12

Family

ID=26864491

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20423/01A Abandoned AU2042301A (en) 1999-12-03 2000-11-14 1-aminoalkyl-1H-indoles for treating glaucoma

Country Status (2)

Country Link
AU (1) AU2042301A (en)
WO (1) WO2001040183A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6960579B1 (en) 1998-05-19 2005-11-01 Alcon Manufacturing, Ltd. Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
DK1267847T3 (en) * 2000-03-17 2004-03-08 Alcon Inc 5HT2 antagonist for the regulation of IOP and treatment of glaucoma
US6927233B1 (en) 2000-03-17 2005-08-09 Alcon, Inc. 5ht2 agonists for controlling IOP and treating glaucoma
TW593302B (en) 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
WO2004054572A2 (en) 2002-12-13 2004-07-01 Alcon, Inc. Novel benzopyran analogs and their use for the treatment of glaucoma
WO2005053688A1 (en) 2003-11-26 2005-06-16 Alcon, Inc. Substituted furo[2,3-g] indazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
US6989445B2 (en) 2003-12-15 2006-01-24 Alcon, Inc. Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma
US7129257B1 (en) 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
US8685924B2 (en) 2004-08-25 2014-04-01 Takeda Pharmaceutical Company Limited Preventives/remedies for stress urinary incontinence and method of screening the same
US7425572B2 (en) 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
JP5528699B2 (en) 2006-05-16 2014-06-25 武田薬品工業株式会社 Fused heterocyclic compounds and uses thereof
JP5520051B2 (en) 2007-11-15 2014-06-11 武田薬品工業株式会社 Condensed pyridine derivatives and uses thereof
US20120253036A1 (en) 2009-12-11 2012-10-04 Yukinori Nagakura Agent for treating fibromyalgia
EP3405454B1 (en) * 2016-01-21 2021-12-29 Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. Indoline derivatives, compositions comprising them and uses thereof
JPWO2019131902A1 (en) 2017-12-27 2020-12-10 武田薬品工業株式会社 Remedies for stress urinary incontinence and fecal incontinence
US20230219969A1 (en) * 2020-06-10 2023-07-13 Delix Therapeutics, Inc. Isotryptamine psychoplastogens and uses thereof
US20250051276A1 (en) * 2021-12-15 2025-02-13 Delix Therapeutics, Inc. Aryloxy psychoplastogens and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5068234A (en) * 1990-02-26 1991-11-26 Sterling Drug Inc. 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles
CA2036307C (en) * 1990-03-08 2002-07-09 Susan Jean Ward 3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions and method
TW270114B (en) * 1993-10-22 1996-02-11 Hoffmann La Roche
AU3255697A (en) * 1996-06-12 1998-01-07 F. Hoffmann-La Roche Ag A process for the manufacture of 1-(amino-alkyl)-indoles
ES2225998T3 (en) * 1996-11-25 2005-03-16 THE PROCTER & GAMBLE COMPANY COMPOUNDS (2-IMIDAZOLINYLAMINE) INDOL USEFUL AS AGONISTS OF THE ALFA 2 ADRENORRECEPTOR.
GB9819033D0 (en) * 1998-09-01 1998-10-28 Cerebrus Ltd Chemical compounds VI

Also Published As

Publication number Publication date
WO2001040183A1 (en) 2001-06-07

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase