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AU1926500A - 3-substituted pyrrolidines useful as inhibitors of matrix metallo-proteinases - Google Patents

3-substituted pyrrolidines useful as inhibitors of matrix metallo-proteinases

Info

Publication number
AU1926500A
AU1926500A AU19265/00A AU1926500A AU1926500A AU 1926500 A AU1926500 A AU 1926500A AU 19265/00 A AU19265/00 A AU 19265/00A AU 1926500 A AU1926500 A AU 1926500A AU 1926500 A AU1926500 A AU 1926500A
Authority
AU
Australia
Prior art keywords
proteinases
inhibitors
useful
matrix metallo
substituted pyrrolidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU19265/00A
Inventor
Gary A. Flynn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Publication of AU1926500A publication Critical patent/AU1926500A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU19265/00A 1998-12-31 1999-11-30 3-substituted pyrrolidines useful as inhibitors of matrix metallo-proteinases Abandoned AU1926500A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22445698A 1998-12-31 1998-12-31
US09224456 1998-12-31
PCT/US1999/028234 WO2000040553A1 (en) 1998-12-31 1999-11-30 3-substituted pyrrolidines useful as inhibitors of matrix metallo-proteinases

Publications (1)

Publication Number Publication Date
AU1926500A true AU1926500A (en) 2000-07-24

Family

ID=22840773

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19265/00A Abandoned AU1926500A (en) 1998-12-31 1999-11-30 3-substituted pyrrolidines useful as inhibitors of matrix metallo-proteinases

Country Status (5)

Country Link
EP (1) EP1150951A1 (en)
AR (1) AR023079A1 (en)
AU (1) AU1926500A (en)
CA (1) CA2356969A1 (en)
WO (1) WO2000040553A1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE106087T1 (en) * 1987-03-17 1994-06-15 Res Corp Technologies Inc SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE.
NZ334490A (en) * 1996-09-19 2000-08-25 Hoechst Marion Roussel Inc 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives as inhibitors of matrix metalloproteinase
JP2001517245A (en) * 1997-05-29 2001-10-02 メルク エンド カンパニー インコーポレーテッド Biarylalkanoic acids as cell adhesion inhibitors

Also Published As

Publication number Publication date
AR023079A1 (en) 2002-09-04
CA2356969A1 (en) 2000-07-13
EP1150951A1 (en) 2001-11-07
WO2000040553A1 (en) 2000-07-13

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase