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AU1684097A - Beta-secretase isolated from human 293 cells - Google Patents

Beta-secretase isolated from human 293 cells

Info

Publication number
AU1684097A
AU1684097A AU16840/97A AU1684097A AU1684097A AU 1684097 A AU1684097 A AU 1684097A AU 16840/97 A AU16840/97 A AU 16840/97A AU 1684097 A AU1684097 A AU 1684097A AU 1684097 A AU1684097 A AU 1684097A
Authority
AU
Australia
Prior art keywords
beta
cells
human
secretase
isolated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU16840/97A
Inventor
John P. Anderson
Susanna M. S. Chrysler
Pamela S Keim
Sukanto Sinha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Perrigo Co PLC
Original Assignee
Athena Neurosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Athena Neurosciences Inc filed Critical Athena Neurosciences Inc
Publication of AU1684097A publication Critical patent/AU1684097A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
AU16840/97A 1996-12-11 1996-12-11 Beta-secretase isolated from human 293 cells Abandoned AU1684097A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1996/019549 WO1998026059A1 (en) 1996-12-11 1996-12-11 Beta-secretase isolated from human 293 cells

Publications (1)

Publication Number Publication Date
AU1684097A true AU1684097A (en) 1998-07-03

Family

ID=22256256

Family Applications (1)

Application Number Title Priority Date Filing Date
AU16840/97A Abandoned AU1684097A (en) 1996-12-11 1996-12-11 Beta-secretase isolated from human 293 cells

Country Status (2)

Country Link
AU (1) AU1684097A (en)
WO (1) WO1998026059A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9701684D0 (en) 1997-01-28 1997-03-19 Smithkline Beecham Plc Novel compounds
US6844148B1 (en) 1998-09-24 2005-01-18 Pharmacia & Upjohn Company Alzheimer's disease secretase, APP substrates therefor, and uses therefor
CN1502692A (en) * 1998-09-24 2004-06-09 �������Ŷ���Լ��������˾ Alzheimer's disease secretase
EP1939297A1 (en) * 1998-09-24 2008-07-02 Pharmacia & Upjohn Company LLC Alzheimer's disease secretase
US6699671B1 (en) 1998-09-24 2004-03-02 Pharmacia & Upjohn Company Alzheimer's disease secretase, APP substrates therefor, and uses therefor
US6313268B1 (en) 1998-10-16 2001-11-06 Vivian Y. H. Hook Secretases related to Alzheimer's dementia
US6245884B1 (en) 1998-10-16 2001-06-12 Vivian Y. H. Hook Secretases related to alzheimer's dementia
DE19856261C1 (en) * 1998-12-07 2000-03-30 Hoechst Marion Roussel De Gmbh Detection of gamma-secretase by detection of A-beta peptide useful for determining gamma-secretase activity and for identifying inhibitors
US7456007B1 (en) 1998-12-31 2008-11-25 Elan Pharmaceuticals, Inc. β-secretase enzyme compositions and methods
US7115410B1 (en) 1999-02-10 2006-10-03 Elan Pharmaceuticals, Inc. β-secretase enzyme compositions and methods
EP1445263A1 (en) * 1999-02-10 2004-08-11 Elan Pharmaceuticals, Inc. Human beta-secretase enzyme, inhibitors and their compositions and uses
CA2359785A1 (en) 1999-02-10 2000-08-17 John P. Anderson .beta.-secretase enzyme compositions and methods
GB2389182B (en) * 1999-02-10 2004-02-04 Elan Pharm Inc Method of purifying b-secretase
AU3770800A (en) 1999-03-26 2000-10-16 Amgen, Inc. Beta secretase genes and polypeptides
JP4484410B2 (en) 1999-06-28 2010-06-16 オクラホマ メディカル リサーチ ファウンデーション Inhibitors of memapsin 2 and uses thereof
US7514408B1 (en) 1999-12-02 2009-04-07 Elan Pharmaceuticals, Inc. β-secretase enzyme compositions and methods
JP4547152B2 (en) 2001-10-23 2010-09-22 オクラホマ メディカル リサーチ ファウンデーション β-secretase inhibitors and methods of use
KR20130133205A (en) 2010-11-10 2013-12-06 제넨테크, 인크. Methods and compositions for neural disease immunotherapy
WO2016081639A1 (en) 2014-11-19 2016-05-26 Genentech, Inc. Antibodies against bace1 and use thereof for neural disease immunotherapy
EP3221361B1 (en) 2014-11-19 2021-04-21 Genentech, Inc. Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE910713A1 (en) * 1990-03-05 1991-09-11 Cephalon Inc Chymotrypsin-like proteases
US5292652A (en) * 1990-10-05 1994-03-08 Athena Neurosciences, Inc. Amyloidin protease and uses thereof

Also Published As

Publication number Publication date
WO1998026059A1 (en) 1998-06-18

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