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AU1675692A - Medicaments containing azacyclodiphosphonic acid derivatives, novel azacyclodiphosphonic acid derivatives and process for producing them - Google Patents

Medicaments containing azacyclodiphosphonic acid derivatives, novel azacyclodiphosphonic acid derivatives and process for producing them

Info

Publication number
AU1675692A
AU1675692A AU16756/92A AU1675692A AU1675692A AU 1675692 A AU1675692 A AU 1675692A AU 16756/92 A AU16756/92 A AU 16756/92A AU 1675692 A AU1675692 A AU 1675692A AU 1675692 A AU1675692 A AU 1675692A
Authority
AU
Australia
Prior art keywords
acid derivatives
azacyclodiphosphonic
novel
producing
medicaments containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU16756/92A
Inventor
Frieder Bauss
Angelika Esswein
Harald Zilch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of AU1675692A publication Critical patent/AU1675692A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532—Seven-(or more) membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Medicaments for the treatment of bone metabolism disorders containing at least one compound of formula (I) in which n is a whole number between 7 and 16 and R is hydrogen or C1?-C4?-alkyl, and their pharmacologically acceptable salts and novel azacycloalkane-2,2-diphosphonic acid derivatives.
AU16756/92A 1991-05-04 1992-05-04 Medicaments containing azacyclodiphosphonic acid derivatives, novel azacyclodiphosphonic acid derivatives and process for producing them Abandoned AU1675692A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4114586 1991-05-04
DE4114586A DE4114586A1 (en) 1991-05-04 1991-05-04 MEDICINAL PRODUCTS CONTAINING AZACYCLODIPHOSPHONIC ACID DERIVATIVES, NEW AZACYCLODIPHOSPHONIC ACID DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF

Publications (1)

Publication Number Publication Date
AU1675692A true AU1675692A (en) 1992-12-21

Family

ID=6430977

Family Applications (1)

Application Number Title Priority Date Filing Date
AU16756/92A Abandoned AU1675692A (en) 1991-05-04 1992-05-04 Medicaments containing azacyclodiphosphonic acid derivatives, novel azacyclodiphosphonic acid derivatives and process for producing them

Country Status (7)

Country Link
EP (1) EP0584115B1 (en)
JP (1) JPH06506931A (en)
AT (1) ATE141608T1 (en)
AU (1) AU1675692A (en)
CA (1) CA2109318A1 (en)
DE (2) DE4114586A1 (en)
WO (1) WO1992019628A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4222910A1 (en) * 1992-07-11 1994-01-13 Asta Medica Ag New phospholipid derivatives
US6172050B1 (en) 1992-07-11 2001-01-09 Asta Medica Aktiengesellschaft Phospholipid derivatives
GB9325113D0 (en) * 1993-12-08 1994-02-09 Albright & Wilson Substituted phosphonic acids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2343196C3 (en) * 1973-08-27 1980-01-10 Henkel Kgaa, 4000 Duesseldorf Aiacycloalkan-2 ^ -diphosphonic acids or their water-soluble salts
DE2541981A1 (en) * 1975-09-20 1977-03-24 Bayer Ag Azacycloalkane diphosphonic acid metal sequestrants - made by reacting lactams with phosphorus trihalide in the presence of specified quantities of water
DE3808074A1 (en) * 1988-03-11 1989-09-21 Henkel Kgaa METHOD FOR PRODUCING AZACYCLOALKANE-2,2-DIPHOSPHONIC ACIDS

Also Published As

Publication number Publication date
EP0584115A1 (en) 1994-03-02
CA2109318A1 (en) 1992-11-05
EP0584115B1 (en) 1996-08-21
DE59206959D1 (en) 1996-09-26
DE4114586A1 (en) 1992-11-05
WO1992019628A1 (en) 1992-11-12
JPH06506931A (en) 1994-08-04
ATE141608T1 (en) 1996-09-15

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