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AU1272295A - Proinsulin-like compounds - Google Patents

Proinsulin-like compounds

Info

Publication number
AU1272295A
AU1272295A AU12722/95A AU1272295A AU1272295A AU 1272295 A AU1272295 A AU 1272295A AU 12722/95 A AU12722/95 A AU 12722/95A AU 1272295 A AU1272295 A AU 1272295A AU 1272295 A AU1272295 A AU 1272295A
Authority
AU
Australia
Prior art keywords
proinsulin
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU12722/95A
Inventor
Asser Andersen
Thomas Kjeldsen
Claus Kristensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK140093A external-priority patent/DK140093D0/en
Priority claimed from DK139993A external-priority patent/DK139993D0/en
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of AU1272295A publication Critical patent/AU1272295A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU12722/95A 1993-12-17 1994-12-16 Proinsulin-like compounds Abandoned AU1272295A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DK1399/93 1993-12-17
DK1400/93 1993-12-17
DK140093A DK140093D0 (en) 1993-12-17 1993-12-17 PRODUCT
DK139993A DK139993D0 (en) 1993-12-17 1993-12-17 PRODUCT
DK029/94 1994-01-07
DK2994 1994-01-07
PCT/DK1994/000471 WO1995016708A1 (en) 1993-12-17 1994-12-16 Proinsulin-like compounds

Publications (1)

Publication Number Publication Date
AU1272295A true AU1272295A (en) 1995-07-03

Family

ID=27220342

Family Applications (1)

Application Number Title Priority Date Filing Date
AU12722/95A Abandoned AU1272295A (en) 1993-12-17 1994-12-16 Proinsulin-like compounds

Country Status (2)

Country Link
AU (1) AU1272295A (en)
WO (1) WO1995016708A1 (en)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (en) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa NOVEL BIOLOGICALLY ACTIVE POLYPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
KR0150565B1 (en) * 1995-02-15 1998-08-17 김정재 A process for preparing human proinsulin by recombinant dna technology
US5622932A (en) * 1995-05-05 1997-04-22 Eli Lilly And Company IGF-1 superagonists
AU5724996A (en) * 1995-05-05 1996-11-21 Eli Lilly And Company Single chain insulin with high bioactivity
WO2001077137A1 (en) 2000-04-12 2001-10-18 Human Genome Sciences, Inc. Albumin fusion proteins
US7378390B2 (en) 1999-12-29 2008-05-27 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
HUP0301640A2 (en) 1999-12-29 2003-08-28 Novo Nordisk A/S. Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
ES2307544T3 (en) * 1999-12-29 2008-12-01 Novo Nordisk A/S METHOD OF PRODUCTION OF INSULIN PRECURSORS AND INSULIN PRECURSORS ANALOGS.
US6777207B2 (en) 1999-12-29 2004-08-17 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
US6521738B2 (en) 1999-12-29 2003-02-18 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogs
US7105314B2 (en) 2001-04-02 2006-09-12 Novo Nordisk A/S Method for making human insulin precursors
AU2002316807A1 (en) * 2001-06-08 2002-12-23 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogs
EP2277889B1 (en) 2001-12-21 2014-07-09 Human Genome Sciences, Inc. Fusion proteins of albumin and interferon beta
EP1594530A4 (en) 2003-01-22 2006-10-11 Human Genome Sciences Inc Albumin fusion proteins
ATE517119T1 (en) * 2003-12-03 2011-08-15 Novo Nordisk As SINGLE CHAIN INSULIN
JP5864834B2 (en) 2006-09-22 2016-02-17 ノボ・ノルデイスク・エー／エス Protease resistant insulin analogue
ES2632504T3 (en) 2007-11-20 2017-09-13 Ambrx, Inc. Modified insulin polypeptides and their uses
KR101775000B1 (en) 2009-06-26 2017-09-04 노보 노르디스크 에이/에스 Preparation comprising insulin, nicotinamide and an amino acid
CN103328006A (en) 2010-12-14 2013-09-25 诺沃—诺迪斯克有限公司 Preparation comprising insulin, nicotinamide and an amino acid
WO2012080320A1 (en) 2010-12-14 2012-06-21 Novo Nordisk A/S Fast-acting insulin in combination with long-acting insulin
US9006176B2 (en) 2011-10-18 2015-04-14 AmideBio LLC Chemically and thermodynamically stable insulin analogues and improved methods for their production
WO2013086785A1 (en) * 2011-12-15 2013-06-20 Qin Shulin Compound and composition having hypoglycemic effect and use thereof
WO2013186138A1 (en) 2012-06-14 2013-12-19 Novo Nordisk A/S Preparation comprising insulin, nicotinamide and arginine
EP2925345B1 (en) 2012-12-03 2018-09-05 Merck Sharp & Dohme Corp. Method for making o-glycosylated carboxy terminal portion (ctp) peptide-based insulin and insulin analogues
US9163073B2 (en) 2013-04-17 2015-10-20 Amidebio, Llc Chemically and thermodynamically stable insulin analogues and improved methods for their production
BR112016007176A2 (en) 2013-10-04 2018-01-23 Merck Sharp & Dohme conjugate, composition, uses of a conjugate and composition, and method for treating an individual having diabetes
GB201321489D0 (en) 2013-12-05 2014-01-22 Chemical & Biopharmaceutical Lab Of Patras S A Biologically active insulin derivatives
CA3014641C (en) 2014-11-21 2020-08-18 Songnian Lin Insulin receptor partial agonists
WO2016144658A1 (en) 2015-03-10 2016-09-15 Merck Sharp & Dohme Corp. Process for preparing recombinant insulin using microfiltration
US10745457B2 (en) 2015-09-02 2020-08-18 Merck Sharp & Dohme Corp. Process for obtaining insulin with correctly formed disulfide bonds
WO2017189342A1 (en) 2016-04-26 2017-11-02 Merck Sharp & Dohme Corp. Insulin dimer-incretin conjugates
EP3463429A4 (en) 2016-05-24 2020-07-22 Merck Sharp & Dohme Corp. INSULIN RECEPTOR PART AGONISTS AND GLP-1 ANALOG
EP3463413A4 (en) 2016-05-25 2020-03-04 Merck Sharp & Dohme Corp. PARTIAL INSULIN RECEPTOR AGONISTS
MX2019000677A (en) 2016-07-18 2019-06-10 Eth Zuerich B-cell-mimetic cells.
EP3272877A1 (en) 2016-07-18 2018-01-24 ETH Zurich B-cell-mimetic cells
US11230585B2 (en) 2016-09-06 2022-01-25 Chemical & Biopharmaceutical Laboratories Of Patra Proinsulin derivatives
WO2018175272A1 (en) 2017-03-23 2018-09-27 Merck Sharp & Dohme Corp. Glucose responsive insulin comprising a tri-valent sugar cluster for treatment of diabetes
EP3980052A4 (en) 2019-06-06 2023-08-23 Merck Sharp & Dohme LLC GLUCOSE-SENSITIVE INSULIN CONJUGATES
JP2023510218A (en) 2019-12-30 2023-03-13 ガン アンド リー ファーマスゥーティカルズ カンパニー リミテッド Long-acting GLP-1 compounds
BR112022013009A2 (en) 2019-12-30 2022-09-06 Gan & Lee Pharmaceuticals Co Ltd INSULIN DERIVATIVES, PHARMACEUTICAL COMPOSITION, INSULIN DERIVATIVE USE AND METHODS TO TREAT OR PREVENT DIABETES, TO INCREASE THE CAPACITY OF AN INSULIN DERIVATIVE, AND TO INCREASE THE POTENCY OF AN INSULIN DERIVATIVE
US20250340610A1 (en) 2022-01-28 2025-11-06 Gan & Lee Pharmaceuticals Co., Ltd. Acylated insulin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1285023A (en) * 1968-08-09 1972-08-09 Novo Terapeutisk Labor As Improvements in or relating to injectable insulin preparations
NZ223630A (en) * 1987-02-25 1989-11-28 Novo Industri As Insulin derivative and pharmaceutical compositions
ATE101620T1 (en) * 1988-06-23 1994-03-15 Hoechst Ag MINI-PROINSULIN, ITS PREPARATION AND USE.
ATE93238T1 (en) * 1988-07-20 1993-09-15 Novo Nordisk As HUMAN INSULIN PLANTS AND PREPARATIONS THEREOF.
US5158875A (en) * 1989-08-25 1992-10-27 Amgen Inc. Production of biologically active insulin-like growth factor i from high expression host cell systems
JPH07508025A (en) * 1992-05-08 1995-09-07 トーマス・ジェファーソン・ユニバーシティ Insulin-like growth factor (IGF-1) analogs

Also Published As

Publication number Publication date
WO1995016708A1 (en) 1995-06-22

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