ATE79404T1 - Verfahren zur herstellung von hepatitis-b-virus- innenkoerperantigen (hbcag) in hefe. - Google Patents
Verfahren zur herstellung von hepatitis-b-virus- innenkoerperantigen (hbcag) in hefe.Info
- Publication number
- ATE79404T1 ATE79404T1 AT87304314T AT87304314T ATE79404T1 AT E79404 T1 ATE79404 T1 AT E79404T1 AT 87304314 T AT87304314 T AT 87304314T AT 87304314 T AT87304314 T AT 87304314T AT E79404 T1 ATE79404 T1 AT E79404T1
- Authority
- AT
- Austria
- Prior art keywords
- hepatitis
- hbcag
- yeast
- production
- internal body
- Prior art date
Links
- 241000700721 Hepatitis B virus Species 0.000 title abstract 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 101710132601 Capsid protein Proteins 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 108010058643 Fungal Proteins Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86655886A | 1986-05-23 | 1986-05-23 | |
| EP87304314A EP0251460B1 (de) | 1986-05-23 | 1987-05-15 | Verfahren zur Herstellung von Hepatitis-B-Virus-Innenkörperantigen (HBcAg) in Hefe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE79404T1 true ATE79404T1 (de) | 1992-08-15 |
Family
ID=25347871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87304314T ATE79404T1 (de) | 1986-05-23 | 1987-05-15 | Verfahren zur herstellung von hepatitis-b-virus- innenkoerperantigen (hbcag) in hefe. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0251460B1 (de) |
| JP (1) | JPS6332491A (de) |
| AT (1) | ATE79404T1 (de) |
| DE (1) | DE3781049T2 (de) |
| DK (1) | DK257887A (de) |
| IE (1) | IE59389B1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0300213A1 (de) * | 1987-06-22 | 1989-01-25 | Hexal-Pharma Gentechnik GmbH & Co. KG | Virale, immunogen wirksame Peptidpartikel von Hepatitis A |
| US4963483A (en) * | 1987-10-13 | 1990-10-16 | Merck & Co., Inc. | Method for producing hepatitis B virus proteins in yeast |
| EP0491077A1 (de) * | 1990-12-19 | 1992-06-24 | Medeva Holdings B.V. | Zusammensetzung verwendbar als therapeutisches Mittel gegen chronische virale Leberkrankheiten |
| RU2216590C1 (ru) * | 2002-02-26 | 2003-11-20 | Государственный научный центр вирусологии и биотехнологии "Вектор" | Рекомбинантный аттенуированный штамм бактерий salmonella typhimurium t10/pkhbc - продуцент корового антигена вируса гепатита в |
| JP4895281B2 (ja) * | 2006-10-16 | 2012-03-14 | 日本電産リード株式会社 | コネクタ |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3381619D1 (de) * | 1982-08-16 | 1990-07-05 | Chemo Sero Therapeut Res Inst | Pendelvektor. |
| ATE73349T1 (de) * | 1984-06-18 | 1992-03-15 | Chiron Corp | Hepatitisoberflaechenantigenpartikelvakzin. |
-
1987
- 1987-05-11 IE IE122487A patent/IE59389B1/en not_active IP Right Cessation
- 1987-05-15 EP EP87304314A patent/EP0251460B1/de not_active Expired - Lifetime
- 1987-05-15 AT AT87304314T patent/ATE79404T1/de not_active IP Right Cessation
- 1987-05-15 DE DE8787304314T patent/DE3781049T2/de not_active Expired - Fee Related
- 1987-05-21 DK DK257887A patent/DK257887A/da not_active Application Discontinuation
- 1987-05-23 JP JP62125046A patent/JPS6332491A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK257887D0 (da) | 1987-05-21 |
| DE3781049D1 (de) | 1992-09-17 |
| EP0251460A3 (en) | 1988-07-20 |
| DE3781049T2 (de) | 1993-03-04 |
| JPS6332491A (ja) | 1988-02-12 |
| DK257887A (da) | 1987-11-24 |
| EP0251460A2 (de) | 1988-01-07 |
| IE871224L (en) | 1987-11-23 |
| EP0251460B1 (de) | 1992-08-12 |
| IE59389B1 (en) | 1994-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |