ATE78162T1 - 5-ht3-rezeptor-antagonisten zur behandlung von husten und bronchokonstriktion. - Google Patents
5-ht3-rezeptor-antagonisten zur behandlung von husten und bronchokonstriktion.Info
- Publication number
- ATE78162T1 ATE78162T1 AT88909596T AT88909596T ATE78162T1 AT E78162 T1 ATE78162 T1 AT E78162T1 AT 88909596 T AT88909596 T AT 88909596T AT 88909596 T AT88909596 T AT 88909596T AT E78162 T1 ATE78162 T1 AT E78162T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- bronchoconstriction
- cough
- pct
- receptor antagonists
- Prior art date
Links
- 206010006482 Bronchospasm Diseases 0.000 title abstract 2
- 230000007885 bronchoconstriction Effects 0.000 title abstract 2
- 102000035037 5-HT3 receptors Human genes 0.000 title 1
- 108091005477 5-HT3 receptors Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229940113081 5 Hydroxytryptamine 3 receptor antagonist Drugs 0.000 abstract 1
- 206010011224 Cough Diseases 0.000 abstract 1
- 239000003369 serotonin 5-HT3 receptor antagonist Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Electrotherapy Devices (AREA)
- Conductive Materials (AREA)
- Indole Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878726716A GB8726716D0 (en) | 1987-11-14 | 1987-11-14 | Treatment |
| GB878726717A GB8726717D0 (en) | 1987-11-14 | 1987-11-14 | Treatment |
| PCT/GB1988/000994 WO1989004660A1 (en) | 1987-11-14 | 1988-11-14 | 5-ht3 receptor antagonists for treatment of cough and bronchoconstriction |
| EP88909596A EP0340270B1 (de) | 1987-11-14 | 1988-11-14 | 5-ht3-rezeptor-antagonisten zur behandlung von husten und bronchokonstriktion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE78162T1 true ATE78162T1 (de) | 1992-08-15 |
Family
ID=26293045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88909596T ATE78162T1 (de) | 1987-11-14 | 1988-11-14 | 5-ht3-rezeptor-antagonisten zur behandlung von husten und bronchokonstriktion. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5098909A (de) |
| EP (1) | EP0340270B1 (de) |
| JP (1) | JPH02502185A (de) |
| KR (1) | KR890701099A (de) |
| AT (1) | ATE78162T1 (de) |
| AU (1) | AU616706B2 (de) |
| DE (1) | DE3872872T2 (de) |
| DK (1) | DK345889D0 (de) |
| WO (1) | WO1989004660A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992000103A1 (en) * | 1990-06-28 | 1992-01-09 | Beecham Group Plc | Pharmaceutical preparations |
| HU211081B (en) * | 1990-12-18 | 1995-10-30 | Sandoz Ag | Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same |
| AU2295792A (en) * | 1991-06-26 | 1993-01-25 | Sepracor, Inc. | Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron |
| CA2371822A1 (en) | 1999-03-01 | 2000-09-08 | Sepracor Inc. | Methods for treating apnea and apnea disorders using optically pure r(+)ondansetron |
| CN1355698A (zh) * | 1999-06-15 | 2002-06-26 | 呼吸器有限公司 | 可用作治疗有关支气管收缩的机能障碍的药物的化合物 |
| GB9918425D0 (en) * | 1999-08-04 | 1999-10-06 | Novartis Ag | Organic compounds |
| AU2001225663A1 (en) * | 2000-06-15 | 2001-12-24 | Respiratorius Ab | A composition comprising a combination of receptor agonists and antagonists |
| CZ2005252A3 (cs) * | 2002-09-25 | 2005-11-16 | Memory Pharmaceuticals Corporation | Indazoly, benzothiazoly a benzoisothiazoly jejich příprava a použití |
| WO2004091606A1 (en) * | 2003-04-16 | 2004-10-28 | Orchid Chemicals & Pharmaceuticals, Ltd. | Treatment of bronchial asthma using 5-ht3 receptor antagonists |
| PT1697378E (pt) | 2003-12-22 | 2008-02-28 | Memory Pharm Corp | Indoles, 1h-indazoles, 1,2-benzisoxazoles e 1,2-benzisotiazoles, sua preparação e utilizações |
| EP1735306A2 (de) | 2004-03-25 | 2006-12-27 | Memory Pharmaceuticals Corporation | Indazole, benzothiazole, benzoisothiazole, benzisoxazole und deren herstellung und verwendungen |
| US7488737B2 (en) * | 2004-04-22 | 2009-02-10 | Memory Pharmaceutical Corporation | Indoles, 1H-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof |
| JP2007538011A (ja) * | 2004-05-07 | 2007-12-27 | メモリー・ファーマシューティカルズ・コーポレイション | １ｈ−インダゾール、ベンゾチアゾール、１，２−ベンゾイソキサゾール、１，２−ベンゾイソチアゾール、およびクロモン、ならびにそれらの調製および使用 |
| RU2418797C2 (ru) | 2004-12-22 | 2011-05-20 | Мемори Фармасьютиклз Корпорейшн | Лиганды никотинового рецептора альфа-7, их получение и применение |
| US8106066B2 (en) | 2005-09-23 | 2012-01-31 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3650772T2 (de) * | 1985-04-27 | 2003-04-03 | F. Hoffmann-La Roche Ag, Basel | Derivate von Indazole-3-carboxamide und -3-carboxylsäure |
-
1988
- 1988-11-14 AT AT88909596T patent/ATE78162T1/de not_active IP Right Cessation
- 1988-11-14 US US07/381,666 patent/US5098909A/en not_active Expired - Fee Related
- 1988-11-14 AU AU26264/88A patent/AU616706B2/en not_active Ceased
- 1988-11-14 WO PCT/GB1988/000994 patent/WO1989004660A1/en not_active Ceased
- 1988-11-14 DE DE8888909596T patent/DE3872872T2/de not_active Expired - Fee Related
- 1988-11-14 EP EP88909596A patent/EP0340270B1/de not_active Expired - Lifetime
- 1988-11-14 JP JP63508864A patent/JPH02502185A/ja active Pending
-
1989
- 1989-07-12 DK DK345889A patent/DK345889D0/da not_active Application Discontinuation
- 1989-07-13 KR KR1019890701320A patent/KR890701099A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1989004660A1 (en) | 1989-06-01 |
| DE3872872D1 (de) | 1992-08-20 |
| DK345889A (da) | 1989-07-12 |
| DE3872872T2 (de) | 1993-02-04 |
| AU616706B2 (en) | 1991-11-07 |
| EP0340270B1 (de) | 1992-07-15 |
| KR890701099A (ko) | 1989-12-19 |
| AU2626488A (en) | 1989-06-14 |
| JPH02502185A (ja) | 1990-07-19 |
| DK345889D0 (da) | 1989-07-12 |
| EP0340270A1 (de) | 1989-11-08 |
| US5098909A (en) | 1992-03-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE78162T1 (de) | 5-ht3-rezeptor-antagonisten zur behandlung von husten und bronchokonstriktion. | |
| ATE347892T1 (de) | Verwendung von nmda-antagonisten zur behandlung von schmerzen | |
| DE69925024D1 (de) | Verwendung von eph-rezeptor-antagonisten und agonisten zur behandlung von vaskulären krankheiten | |
| DE69528475D1 (de) | Verwendung von serotonin-antagonisten (5ht3) zur behandlung von fibromyalgie | |
| ATE198830T1 (de) | Verwendung von nikotinanalogen zur behandlung von degenerativen erkrankungen des nervensystems | |
| NO2015027I1 (no) | Mepolizumab | |
| NO890408L (no) | 3-indolpyrodruesyre-derivater og deres farmasoeytiske anvendelse. | |
| DE69805973D1 (de) | Behandlung von herzrythmusstörungen durch hemmung einer multifunktionalen calcium/calmodulin-abhängigen protein kinase | |
| DE69017302D1 (de) | Zentrale Cholecystokinin-Antagonisten zur Behandlung von psychiatrischen Krankheiten. | |
| NO962665D0 (no) | Forbindelser med veksthormonfrigjörende egenskaper | |
| DE3650647D1 (de) | Arzneimittel zur Behandlung von Anxietas | |
| IL83687A0 (de) | ||
| ATE224719T1 (de) | Phosphatidsäure enthaltende zusammensetzungen | |
| EP0128159A4 (de) | Vorrichtung und verfahren zur thermischen behandlung von halbleitersubstraten. | |
| BR9508406A (pt) | Uso de um composto e método para o tratamento e/ou profilaxia em mamíferos | |
| DE69207698D1 (de) | Arylalkylester der 4,5-dihydoxy-9,10-dihydro-9,10-dioxo-2-anthracencarbonsäure und deren therapeutische verwendung | |
| DE69112573D1 (de) | Immunstimulierendes arzneimittel, das polare glycopeptidolipide von mycobakterium-chelonae enthält. | |
| DE69023006D1 (de) | Verfahren zur behandlung von thrombocytopenie und dafür geeignete pharmazeutische zusammensetzungen. | |
| ATE222768T1 (de) | Ctla-8 in kombination mit g-csf oder mit g-csf und il-6, und verwendung vom ctla-8 zur behandlung von infektionen | |
| ATE167628T1 (de) | Verfahren und zusammensetzungen zur behandlung von krankheiten verbunden mit mangelhaften immunfunktion | |
| OA08298A (fr) | Nouvelles N-(aminométhyl-5 oxazolin-2 yl-2) N'-phénylurées, leur méthode de préparation ainsi que leur application thérapeutique. | |
| EA199800859A1 (ru) | Способ лечения при ядовитых укусах и ужалениях | |
| ATE80998T1 (de) | Verwendung von nalmefen zur herstellung eines arzneimittels zur behandlung der schaedigung des zentralnervensystems. | |
| ATE333287T1 (de) | Prophylaxe und behandlung von autoimmunen entmyelinisierungserkrankungen durch fas- antagonisten | |
| NO974687D0 (no) | Kondenserte <beta>-carboliner |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |