ATE406463T1 - Methode zur krebsdiagnose mittels nachweis von dna und rna im kreislauf - Google Patents
Methode zur krebsdiagnose mittels nachweis von dna und rna im kreislaufInfo
- Publication number
- ATE406463T1 ATE406463T1 AT05007508T AT05007508T ATE406463T1 AT E406463 T1 ATE406463 T1 AT E406463T1 AT 05007508 T AT05007508 T AT 05007508T AT 05007508 T AT05007508 T AT 05007508T AT E406463 T1 ATE406463 T1 AT E406463T1
- Authority
- AT
- Austria
- Prior art keywords
- rna
- dna
- cancer
- circulation
- detection
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 5
- 201000011510 cancer Diseases 0.000 title abstract 5
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 210000002966 serum Anatomy 0.000 abstract 2
- 230000004544 DNA amplification Effects 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000003208 gene overexpression Methods 0.000 abstract 1
- 238000011002 quantification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05007508A EP1712639B1 (de) | 2005-04-06 | 2005-04-06 | Methode zur Krebsdiagnose mittels Nachweis von DNA und RNA im Kreislauf |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE406463T1 true ATE406463T1 (de) | 2008-09-15 |
Family
ID=34934801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05007508T ATE406463T1 (de) | 2005-04-06 | 2005-04-06 | Methode zur krebsdiagnose mittels nachweis von dna und rna im kreislauf |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7700286B2 (de) |
| EP (1) | EP1712639B1 (de) |
| AT (1) | ATE406463T1 (de) |
| DE (1) | DE602005009324D1 (de) |
| ES (1) | ES2313143T3 (de) |
| PL (1) | PL1712639T3 (de) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7425217B2 (en) * | 2000-11-16 | 2008-09-16 | Maier Nathan C | System and method for inhibiting cellular proliferation with tachykinins |
| PL1712639T3 (pl) | 2005-04-06 | 2009-02-27 | Maurice Stroun | Sposób diagnozowania nowotworu przez wykrywanie krążącego DNA i RNA |
| EP2557517B1 (de) | 2007-07-23 | 2022-10-26 | The Chinese University of Hong Kong | Bestimmung eines Nukleinsäuresequenzungleichgewichts |
| US12180549B2 (en) | 2007-07-23 | 2024-12-31 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using genomic sequencing |
| FR2928657B1 (fr) * | 2008-03-14 | 2013-12-20 | Chu Saint Etienne Chu Hopital Nord | Methode, procede, et kit de diagnostic, pronostic, suivi d'un cancer |
| EP2318552B1 (de) | 2008-09-05 | 2016-11-23 | TOMA Biosciences, Inc. | Verfahren zum stratifizieren und annotieren der behandlungsoptionen eines krebsmedikaments |
| JP5410722B2 (ja) * | 2008-09-30 | 2014-02-05 | 三菱化学メディエンス株式会社 | 膵臓の組織傷害あるいは細胞増殖性疾患の検出方法 |
| US9090948B2 (en) | 2008-09-30 | 2015-07-28 | Abbott Molecular Inc. | Primers and probes for detecting human papillomavirus and human beta globin sequences in test samples |
| US8404444B2 (en) * | 2009-02-25 | 2013-03-26 | Diacarta Llc | Method for predicting the level of damage to cells by measuring free circulating Alu nucleic acid |
| US9085798B2 (en) | 2009-04-30 | 2015-07-21 | Prognosys Biosciences, Inc. | Nucleic acid constructs and methods of use |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| HUE026666T2 (en) | 2010-04-05 | 2016-07-28 | Prognosys Biosciences Inc | Spatially encoded biological assays |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| US9309556B2 (en) | 2010-09-24 | 2016-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | Direct capture, amplification and sequencing of target DNA using immobilized primers |
| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| CN103403182B (zh) | 2010-11-30 | 2015-11-25 | 香港中文大学 | 与癌症相关的遗传或分子畸变的检测 |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| HUE068153T2 (hu) | 2011-04-15 | 2024-12-28 | Univ Johns Hopkins | Biztonságos szekvenálási rendszer |
| US10011871B2 (en) | 2012-02-17 | 2018-07-03 | Fred Hutchinson Cancer Research Center | Compositions and methods for accurately identifying mutations |
| US9892230B2 (en) | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
| US10876152B2 (en) | 2012-09-04 | 2020-12-29 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| MX367963B (es) | 2012-09-04 | 2019-09-11 | Guardant Health Inc | Métodos para detectar mutaciones raras y variación en el número de copias. |
| US11913065B2 (en) | 2012-09-04 | 2024-02-27 | Guardent Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| USRE50065E1 (en) | 2012-10-17 | 2024-07-30 | 10X Genomics Sweden Ab | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
| EP3447495B2 (de) | 2012-10-29 | 2024-03-13 | The Johns Hopkins University | Papanicolaou-test für ovarial- und endometriumkarzinome |
| EP3013984B1 (de) | 2013-06-25 | 2023-03-22 | Prognosys Biosciences, Inc. | Verfahren zur bestimmung der räumlichen muster biologischer ziele in einer probe |
| EP3063295B1 (de) | 2013-10-29 | 2017-12-13 | Region Syddanmark | Verfahren zur analyse von körperflüssigkeitsproben |
| US11286519B2 (en) | 2013-12-11 | 2022-03-29 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| IL274464B2 (en) | 2013-12-11 | 2023-08-01 | Accuragen Holdings Ltd | Preparations and methods for the detection of rare sequence variants |
| US11859246B2 (en) | 2013-12-11 | 2024-01-02 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
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| TWI895765B (zh) | 2014-07-18 | 2025-09-01 | 香港中文大學 | Dna混合物中之組織甲基化模式分析 |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| US10364467B2 (en) | 2015-01-13 | 2019-07-30 | The Chinese University Of Hong Kong | Using size and number aberrations in plasma DNA for detecting cancer |
| CN107532124B (zh) | 2015-03-27 | 2022-08-09 | 精密科学公司 | 检测食管疾病 |
| EP4119677B1 (de) | 2015-04-10 | 2023-06-28 | Spatial Transcriptomics AB | Räumlich getrennte multiplex-nukleinsäureanalyse von biologischen proben |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| EP3359693B1 (de) | 2015-10-09 | 2025-03-19 | Accuragen Holdings Limited | Verfahren zur anreicherung von amplifikationsprodukten |
| CA3233310A1 (en) | 2015-10-30 | 2017-05-04 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay and isolation and detection of dna from plasma |
| WO2017096322A1 (en) | 2015-12-03 | 2017-06-08 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| JP2019507585A (ja) | 2015-12-17 | 2019-03-22 | ガーダント ヘルス， インコーポレイテッド | 無細胞ｄｎａの分析による腫瘍遺伝子コピー数を決定するための方法 |
| US11427866B2 (en) | 2016-05-16 | 2022-08-30 | Accuragen Holdings Limited | Method of improved sequencing by strand identification |
| CN109844133A (zh) | 2016-08-15 | 2019-06-04 | 安可济控股有限公司 | 检测罕见序列变体的组合物和方法 |
| US9850523B1 (en) | 2016-09-30 | 2017-12-26 | Guardant Health, Inc. | Methods for multi-resolution analysis of cell-free nucleic acids |
| KR20240155386A (ko) | 2016-09-30 | 2024-10-28 | 가던트 헬쓰, 인크. | 무세포 핵산의 다중-해상도 분석 방법 |
| WO2018099418A1 (en) | 2016-11-30 | 2018-06-07 | The Chinese University Of Hong Kong | Analysis of cell-free dna in urine and other samples |
| AU2018211956B2 (en) | 2017-01-27 | 2024-06-20 | Exact Sciences Corporation | Detection of colon neoplasia by analysis of methylated DNA |
| US10907211B1 (en) | 2017-02-16 | 2021-02-02 | Quantgene Inc. | Methods and compositions for detecting cancer biomarkers in bodily fluids |
| WO2018183942A1 (en) | 2017-03-31 | 2018-10-04 | Grail, Inc. | Improved library preparation and use thereof for sequencing-based error correction and/or variant identification |
| IL319255A (en) | 2017-08-07 | 2025-04-01 | Univ Johns Hopkins | Methods and materials for cancer assessment and treatment |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| US11203782B2 (en) | 2018-03-29 | 2021-12-21 | Accuragen Holdings Limited | Compositions and methods comprising asymmetric barcoding |
| US12049665B2 (en) | 2018-06-12 | 2024-07-30 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| WO2020123320A2 (en) | 2018-12-10 | 2020-06-18 | 10X Genomics, Inc. | Imaging system hardware |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11643693B2 (en) | 2019-01-31 | 2023-05-09 | Guardant Health, Inc. | Compositions and methods for isolating cell-free DNA |
| MX2021013834A (es) | 2019-05-17 | 2022-06-29 | Univ Johns Hopkins | Detección rápida de aneuploidía. |
| WO2020243579A1 (en) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| WO2021091611A1 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Spatially-tagged analyte capture agents for analyte multiplexing |
| WO2021133849A1 (en) | 2019-12-23 | 2021-07-01 | 10X Genomics, Inc. | Methods for spatial analysis using rna-templated ligation |
| JP2023513606A (ja) | 2020-02-14 | 2023-03-31 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 核酸を評価するための方法および材料 |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
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| AU2021283174A1 (en) | 2020-06-02 | 2023-01-05 | 10X Genomics, Inc. | Nucleic acid library methods |
| EP4421186B1 (de) | 2020-06-08 | 2025-08-13 | 10X Genomics, Inc. | Verfahren zur bestimmung eines chirurgischen randes und verfahren zur verwendung davon |
| EP4121555A1 (de) | 2020-12-21 | 2023-01-25 | 10X Genomics, Inc. | Verfahren, zusammensetzungen und systeme zur erfassung von sonden und/oder barcodes |
| ES3008686T3 (en) | 2021-03-18 | 2025-03-24 | 10X Genomics Inc | Multiplex capture of gene and protein expression from a biological sample |
| CN113238052B (zh) * | 2021-04-27 | 2023-07-25 | 中国人民解放军空军军医大学 | MG7-Ag、hTERT及TFF2表达分析在肠上皮化生风险分层及胃癌预警中的应用 |
| EP4582555A3 (de) | 2021-06-03 | 2025-10-22 | 10X Genomics, Inc. | Verfahren, zusammensetzungen, kits und systeme zur verbesserung der analyterfassung zur räumlichen analyse |
| EP4305195A2 (de) | 2021-12-01 | 2024-01-17 | 10X Genomics, Inc. | Verfahren, zusammensetzungen und systeme für verbesserten in-situ-nachweis von analyten und raumanalyse |
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| EP0507852B1 (de) | 1990-01-04 | 1998-04-01 | The Johns Hopkins University | In menschlichen kolorektalkarzinomen fehlendes gen |
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-
2005
- 2005-04-06 PL PL05007508T patent/PL1712639T3/pl unknown
- 2005-04-06 EP EP05007508A patent/EP1712639B1/de not_active Expired - Lifetime
- 2005-04-06 ES ES05007508T patent/ES2313143T3/es not_active Expired - Lifetime
- 2005-04-06 AT AT05007508T patent/ATE406463T1/de not_active IP Right Cessation
- 2005-04-06 DE DE602005009324T patent/DE602005009324D1/de not_active Expired - Lifetime
-
2006
- 2006-01-23 US US11/336,780 patent/US7700286B2/en not_active Ceased
-
2012
- 2012-04-13 US US13/447,104 patent/USRE44596E1/en active Active
-
2013
- 2013-09-27 US US14/039,168 patent/USRE49542E1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2313143T3 (es) | 2009-03-01 |
| DE602005009324D1 (de) | 2008-10-09 |
| US20060228727A1 (en) | 2006-10-12 |
| USRE44596E1 (en) | 2013-11-12 |
| EP1712639A1 (de) | 2006-10-18 |
| PL1712639T3 (pl) | 2009-02-27 |
| EP1712639B1 (de) | 2008-08-27 |
| USRE49542E1 (en) | 2023-06-06 |
| US7700286B2 (en) | 2010-04-20 |
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