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ATE481384T1 - Isoindolderivate als ep4-rezeptoragonisten - Google Patents

Isoindolderivate als ep4-rezeptoragonisten

Info

Publication number
ATE481384T1
ATE481384T1 AT07821299T AT07821299T ATE481384T1 AT E481384 T1 ATE481384 T1 AT E481384T1 AT 07821299 T AT07821299 T AT 07821299T AT 07821299 T AT07821299 T AT 07821299T AT E481384 T1 ATE481384 T1 AT E481384T1
Authority
AT
Austria
Prior art keywords
receptor agonists
isoindole derivatives
derivatives
isoindole
medicine
Prior art date
Application number
AT07821299T
Other languages
English (en)
Inventor
Gerard Giblin
Mark Healy
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE481384T1 publication Critical patent/ATE481384T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/62Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • C07D209/66Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with oxygen atoms in positions 1 and 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT07821299T 2006-10-17 2007-10-15 Isoindolderivate als ep4-rezeptoragonisten ATE481384T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0620619.7A GB0620619D0 (en) 2006-10-17 2006-10-17 Novel compounds
PCT/EP2007/060932 WO2008046798A1 (en) 2006-10-17 2007-10-15 Isoindol derivatives as ep4 receptor agonists

Publications (1)

Publication Number Publication Date
ATE481384T1 true ATE481384T1 (de) 2010-10-15

Family

ID=37507899

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07821299T ATE481384T1 (de) 2006-10-17 2007-10-15 Isoindolderivate als ep4-rezeptoragonisten

Country Status (8)

Country Link
US (1) US20100076048A1 (de)
EP (1) EP2081897B1 (de)
JP (1) JP2010506878A (de)
AT (1) ATE481384T1 (de)
DE (1) DE602007009286D1 (de)
ES (1) ES2352305T3 (de)
GB (1) GB0620619D0 (de)
WO (1) WO2008046798A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2488168A1 (de) 2009-10-14 2012-08-22 Gemmus Pharma Inc. Kombinationstherapie zur behandlung von virusinfektionen
AU2014305843B2 (en) 2013-08-09 2019-08-29 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
CN114340631A (zh) 2019-05-21 2022-04-12 阿德利克斯股份有限公司 用于降低患者的血清磷酸盐的组合

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3300889A (en) * 1965-04-22 1967-01-31 Su Ev Inc Recoil snubber for guns
US3707797A (en) * 1970-11-18 1973-01-02 K Ruth Recoil absorber
US3714726A (en) * 1970-11-25 1973-02-06 P Braun Recoil stock
US3754344A (en) * 1972-04-28 1973-08-28 J Spiliotis Gun recoil absorber
US4439943A (en) * 1982-03-09 1984-04-03 Brakhage Rodney D Recoil reducer
US4910904A (en) * 1989-03-27 1990-03-27 Browning Recoil reducer for firearms
US5031348A (en) * 1990-10-01 1991-07-16 Carey Donald C Gun stock assembly with coordinated comb and recoil
US5173564A (en) * 1992-01-07 1992-12-22 Hammond Jr Claude R Quick detachable stock system and method
US5726377A (en) * 1996-06-19 1998-03-10 Colt's Manufacturing Company, Inc. Gas operated firearm
EP1442744B1 (de) * 1999-08-10 2006-12-20 Glaxo Group Limited EP4 Rezeptor Ligand und Verwendung gegen neuropatischen Schmerzen, Colon Krebs, HIV und Migräne
US6481143B2 (en) * 2000-11-03 2002-11-19 Mccarthy Patrick M. Gun stock with recoil reduction device
GB0103269D0 (en) * 2001-02-09 2001-03-28 Glaxo Group Ltd Napthalene derivatives
US6651371B2 (en) * 2001-06-25 2003-11-25 Richard Mark Fitzpatrick Modular gunstock
US6688031B2 (en) * 2002-05-30 2004-02-10 Gerald Dale Steele Replacement adjustable competition buttstock
US6732466B2 (en) * 2002-08-19 2004-05-11 James K. Bentley Recoil system for the receiver of a firearm
US7398616B1 (en) * 2004-05-21 2008-07-15 Robert Weir Adjustable length heavy duty butt stock assembly for a firearm
US7124529B1 (en) * 2004-12-16 2006-10-24 Havelka Jr Alfred J Axially displaced gun stock recoil system
US7162822B1 (en) * 2005-01-03 2007-01-16 The United States Of America As Represented By The Secretary Of The Army Collapsible buttstock for firearm
KR20080098597A (ko) * 2006-02-03 2008-11-11 글락소 그룹 리미티드 통증의 치료를 위한 벤조이소인돌 유도체
UY30121A1 (es) * 2006-02-03 2007-08-31 Glaxo Group Ltd Nuevos compuestos
US7992337B2 (en) * 2006-03-16 2011-08-09 Ochoa Adam A Method and apparatus to mount recoil dampening apparatus on rifle
GB0615111D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel compounds
GB0615105D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel compounds
US7681351B2 (en) * 2006-11-15 2010-03-23 Enidine, Inc. Hydraulic recoil buffer assembly

Also Published As

Publication number Publication date
EP2081897B1 (de) 2010-09-15
DE602007009286D1 (de) 2010-10-28
ES2352305T3 (es) 2011-02-17
US20100076048A1 (en) 2010-03-25
GB0620619D0 (en) 2006-11-29
JP2010506878A (ja) 2010-03-04
EP2081897A1 (de) 2009-07-29
WO2008046798A1 (en) 2008-04-24

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Legal Events

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