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ATE318915T1 - Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung - Google Patents

Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung

Info

Publication number
ATE318915T1
ATE318915T1 AT97945277T AT97945277T ATE318915T1 AT E318915 T1 ATE318915 T1 AT E318915T1 AT 97945277 T AT97945277 T AT 97945277T AT 97945277 T AT97945277 T AT 97945277T AT E318915 T1 ATE318915 T1 AT E318915T1
Authority
AT
Austria
Prior art keywords
sarp
peptides
apoptosis
production
gene family
Prior art date
Application number
AT97945277T
Other languages
English (en)
Inventor
Samuil Umansky
Hovsep Melkonyan
Original Assignee
Tanox Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26701439&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE318915(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tanox Inc filed Critical Tanox Inc
Application granted granted Critical
Publication of ATE318915T1 publication Critical patent/ATE318915T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT97945277T 1996-09-24 1997-09-24 Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung ATE318915T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2660396P 1996-09-24 1996-09-24
US2836396P 1996-10-11 1996-10-11

Publications (1)

Publication Number Publication Date
ATE318915T1 true ATE318915T1 (de) 2006-03-15

Family

ID=26701439

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97945277T ATE318915T1 (de) 1996-09-24 1997-09-24 Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung

Country Status (11)

Country Link
US (3) US6433155B1 (de)
EP (1) EP0932678B2 (de)
JP (2) JP4299886B2 (de)
AT (1) ATE318915T1 (de)
AU (1) AU737323B2 (de)
CA (1) CA2266325C (de)
DE (1) DE69735375T3 (de)
DK (1) DK0932678T4 (de)
ES (1) ES2263181T5 (de)
PT (1) PT932678E (de)
WO (1) WO1998013493A2 (de)

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AU4899397A (en) * 1997-02-06 1998-08-26 Genetics Institute, Llc Human sdf-5 protein and compositions
CA2224473A1 (en) * 1997-05-21 1998-11-21 Smithkline Beecham Corporation A novel human gene similar to a secreted murine protein sdf5
EP0879885A1 (de) * 1997-05-23 1998-11-25 Smithkline Beecham Corporation GEN für ein sekretiertes-Maus-sFRP-1-Protein ähnliches Protein
AU7704498A (en) * 1997-05-29 1998-12-30 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Human frp and fragments thereof including methods for using them
US20030203446A1 (en) * 1998-10-07 2003-10-30 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
IL142690A0 (en) * 1998-10-30 2002-03-10 Idun Pharmaceuticals Inc Transgenic plants and methods of generating the same
GB9921009D0 (en) * 1999-09-07 1999-11-10 Neuropa Ltd Essential genes and assays relating thereto
US20080166356A9 (en) * 1999-09-13 2008-07-10 Peter Bodine Pharmaceutical compositions and methods of using secreted frizzled related protein
US6600018B1 (en) 2000-04-10 2003-07-29 The United States Of America As Represented By The Department Of Health And Human Services Secreted frizzled related protein, sFRP, fragments and methods of use thereof
CZ20031855A3 (cs) 2000-12-06 2003-09-17 Applied Research Systems Ars Holding N. V. Použití SARP-1 pro léčbu a/nebo prevenci onemocnění sklerodermie
CA2434672C (en) 2001-01-10 2014-03-25 Jeffrey S. Rubin Sfrp and peptide motifs that interact with sfrp and methods of their use
EP1222933A1 (de) * 2001-01-15 2002-07-17 Academisch Ziekenhuis Leiden h.o.d.n., Leids Universitair Medisch Centrum Bildung und/oder Reduktion von neuem Lungengewebe in einer erkranketen Lunge, durch Modulierung des Wnt-Signalwegs
US20030044409A1 (en) * 2001-05-01 2003-03-06 Carson Dennis A. Immunologic compositions and methods for studying and treating cancers expressing frizzled antigens
US7682607B2 (en) 2001-05-01 2010-03-23 The Regents Of The University Of California Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas
AU2003259285A1 (en) * 2002-07-29 2004-02-16 Hmgene, Inc. Methods of identifying adipocyte specific genes, the genes identified, and their uses
US20050054599A1 (en) * 2003-05-02 2005-03-10 Coles John G. Biosynthetic platform for cardioprotective stress response in human fetal heart tissue
EP1697409A1 (de) * 2003-12-16 2006-09-06 Aventis Pharmaceuticals, Inc. Sezerniertes neurales apoptose-inhibierendes protein
TWI661199B (zh) 2004-07-23 2019-06-01 太平洋愛吉生技股份有限公司 檢測膀胱癌之尿液標記物
CA3022238A1 (en) 2005-08-19 2007-02-22 Duke University Stem cell derived factors for treating pathologic conditions
JP2009513708A (ja) * 2005-10-31 2009-04-02 オンコメッド ファーマシューティカルズ インコーポレイテッド 癌の診断および処置のための組成物および方法
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
NZ545243A (en) 2006-02-10 2009-07-31 Pacific Edge Biotechnology Ltd Urine gene expression ratios for detection of cancer
PE20120806A1 (es) * 2006-09-08 2012-07-25 Genentech Inc Antagonistas del gen wnt y su uso en el diagnostico y tratamiento de trastornos mediados por el wnt
CN105079805A (zh) * 2008-09-26 2015-11-25 昂考梅德药品有限公司 卷曲蛋白结合药剂及其应用
TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Ｗｎｔ拮抗劑及治療和篩選方法
KR20130043102A (ko) 2010-04-01 2013-04-29 온코메드 파마슈티칼스, 인크. 프리즐드-결합 작용제 및 그의 용도
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
LT4108671T (lt) 2010-10-01 2025-01-10 Modernatx, Inc. Modifikuoti nukleozidai, nukleotidai, nukleorūgštys bei jų panaudojimas
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP3682905B1 (de) 2011-10-03 2021-12-01 ModernaTX, Inc. Modifizierte nukleoside, nukleotide und nukleinsäuren und verwendungen davon
ES2923757T3 (es) 2011-12-16 2022-09-30 Modernatx Inc Composiciones de ARNm modificado
EP2833923A4 (de) 2012-04-02 2016-02-24 Moderna Therapeutics Inc Modifizierte polynukleotide zur herstellung von proteinen
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US10501512B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
CA2887711A1 (en) 2012-10-23 2014-05-01 Oncomed Pharmaceuticals, Inc. Methods of treating neuroendocrine tumors using wnt pathway-binding agents
US9597380B2 (en) 2012-11-26 2017-03-21 Modernatx, Inc. Terminally modified RNA
EP2950885B1 (de) 2013-02-04 2018-11-21 Oncomed Pharmaceuticals, Inc. Verfahren und überwachung einer behandlung mit einem wnt-pfad-hemmer
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
WO2015048744A2 (en) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucleotides encoding immune modulating polypeptides
MX2016004249A (es) 2013-10-03 2016-11-08 Moderna Therapeutics Inc Polinulcleotidos que codifican el receptor de lipoproteina de baja densidad.

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US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
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US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
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WO1993004169A1 (en) 1991-08-20 1993-03-04 Genpharm International, Inc. Gene targeting in animal cells using isogenic dna constructs
US5639856A (en) * 1993-09-13 1997-06-17 The Regents Of The University Of California Semaphorin gene family
US5663070A (en) * 1993-11-15 1997-09-02 Lxr Biotechnology Inc. Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM
US5759548A (en) 1993-11-30 1998-06-02 Lxr Biotechnology Inc. Compositions which inhibit apoptosis, methods of purifying the compositions and uses thereof
US5672686A (en) * 1994-08-09 1997-09-30 Immunogen, Inc. Bcl-Y - specific antibodies

Also Published As

Publication number Publication date
DK0932678T4 (da) 2010-07-12
JP2009050257A (ja) 2009-03-12
DE69735375T2 (de) 2006-11-30
PT932678E (pt) 2006-07-31
EP0932678B2 (de) 2010-03-10
DE69735375T3 (de) 2010-09-02
US6433155B1 (en) 2002-08-13
AU737323B2 (en) 2001-08-16
ES2263181T3 (es) 2006-12-01
ES2263181T5 (es) 2011-04-07
US7045604B2 (en) 2006-05-16
JP4299886B2 (ja) 2009-07-22
WO1998013493A3 (en) 1998-06-04
CA2266325C (en) 2012-07-17
US20030023061A1 (en) 2003-01-30
CA2266325A1 (en) 1998-04-02
AU4651397A (en) 1998-04-17
DK0932678T3 (da) 2006-05-22
DE69735375D1 (de) 2006-04-27
US20040039184A1 (en) 2004-02-26
US7045596B2 (en) 2006-05-16
JP2002516564A (ja) 2002-06-04
WO1998013493A2 (en) 1998-04-02
EP0932678B1 (de) 2006-03-01
EP0932678A2 (de) 1999-08-04

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