ATE368741T1 - Das nk1 fragment des hepatocytwachstumfaktors/dispersionsfaktors (hgf/sf), varianten davon und deren verwendung - Google Patents

Das nk1 fragment des hepatocytwachstumfaktors/dispersionsfaktors (hgf/sf), varianten davon und deren verwendung

Info

Publication number: ATE368741T1
Authority: AT; Austria
Prior art keywords: variants; hgf; fragment; factor; hepatocyt
Prior art date: 2001-04-27

Application number

AT02720271T

Other languages

English (en)

Inventor

Ermanno Gherardi

Daniel Lietha

Thomas Leon Blundell

Dimitry Yurievich Chirgadze

Original Assignee

Medical Res Council

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-27

Filing date

2002-04-29

Publication date

2007-08-15

2002-04-29 Application filed by Medical Res Council filed Critical Medical Res Council

2007-08-15 Application granted granted Critical

2007-08-15 Publication of ATE368741T1 publication Critical patent/ATE368741T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Physical Education & Sports Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Zoology (AREA)
Toxicology (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Psychiatry (AREA)
Communicable Diseases (AREA)
Diabetes (AREA)
Oncology (AREA)
Virology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)

AT02720271T 2001-04-27 2002-04-29 Das nk1 fragment des hepatocytwachstumfaktors/dispersionsfaktors (hgf/sf), varianten davon und deren verwendung ATE368741T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0110430.6A GB0110430D0 (en)	2001-04-27	2001-04-27	Protein variants and uses thereof

Publications (1)

Publication Number	Publication Date
ATE368741T1 true ATE368741T1 (de)	2007-08-15

Family

ID=9913640

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02720271T ATE368741T1 (de)	2001-04-27	2002-04-29	Das nk1 fragment des hepatocytwachstumfaktors/dispersionsfaktors (hgf/sf), varianten davon und deren verwendung

Country Status (11)

Country	Link
US (3)	US7179786B2 (de)
EP (1)	EP1381681B1 (de)
JP (2)	JP4637452B2 (de)
AT (1)	ATE368741T1 (de)
AU (1)	AU2002251337B2 (de)
CA (1)	CA2440775C (de)
DE (1)	DE60221510T2 (de)
DK (1)	DK1381681T3 (de)
ES (1)	ES2291460T3 (de)
GB (1)	GB0110430D0 (de)
WO (1)	WO2002088354A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0110430D0 (en) *	2001-04-27	2001-06-20	Medical Res Council	Protein variants and uses thereof
US20050107296A1 (en) *	2001-10-31	2005-05-19	Institut Des Vaisseaux Et Du Sang	Isolated peptide of the hepatocyte growth factor and its variants, preparation method and therapeutic use as anti-angiogenic agents
AT412785B (de) *	2003-12-04	2005-07-25	Kungl Andreas J Dr	Gag-bindungsproteine
US7563570B2 (en)	2004-10-29	2009-07-21	Pangaea Biotech	Method of determining a chemotherapeutic regimen for non small cell lung cancer based on BRCA1 expression
US20090215686A1 (en) *	2007-03-05	2009-08-27	Huaqiang Eric Xu	Nk1-based polypeptides and related methods
WO2009062143A2 (en) *	2007-11-09	2009-05-14	New York Medical College	Methods and compositions for the repair and/or regeneration of damaged myocardium using cytokines and variants thereof
WO2011103382A2 (en) *	2010-02-22	2011-08-25	The Brigham And Women's Hospital	Compositions and methods for inducing angiogenesis
WO2011116396A2 (en) *	2010-03-19	2011-09-22	The Board Of Trustees Of The Leland Stanford Junior University	Hepatocyte growth factor fragments that function as potent met receptor agonists and antagonists
EP3604549A1 (de)	2010-11-08	2020-02-05	The Board of Trustees of the Leland Stanford Junior University	Fusionsproteine mit einem manipulierten knottin-peptid und verwendungen davon
WO2013037520A1 (en)	2011-09-16	2013-03-21	Glaxo Group Limited	Modified hgf-1k1 polypeptide
WO2013037521A1 (en)	2011-09-16	2013-03-21	Medical Research Council	Modified hgf-1k1 polypeptide
HUE047148T2 (hu)	2015-01-21	2020-04-28	Univ Lille	MET receptor antagonista proteinek
AU2017204125B1 (en)	2016-06-17	2017-10-26	Crispr Therapeutics Ag	Compositions and methods for the depletion of cd117+ cells
GB201611123D0 (en)	2016-06-27	2016-08-10	Euremab Srl	Anti met antibodiesand uses thereof
IL268058B2 (en)	2017-01-20	2023-09-01	Magenta Therapeutics Inc	Compositions and methods for depleting cd137 plus cells
IT201800000535A1 (it)	2018-01-03	2019-07-03		Procedimenti per la cura del cancro.
CN109535243B (zh)	2019-01-07	2019-09-24	北京诺思兰德生物技术股份有限公司	人肝细胞生长因子突变体及其应用
CN119613527A (zh) *	2024-12-30	2025-03-14	江苏三仪生物工程有限公司	鸡肝细胞生长因子的截短突变体及其在防治肝脏相关疾病方面的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5594115A (en) *	1990-04-09	1997-01-14	Pharmacia & Upjohn Company	Process of purifying recombinant proteins and compounds useful in such process
US6566098B1 (en) *	1990-09-14	2003-05-20	The United States Of America As Represented By The Department Of Health And Human Services	DNA encoding truncated hepatocyte growth factor variants
EP0642580B1 (de) *	1992-05-18	2002-08-21	Genentech, Inc.	Hepatozytwachstumfaktor Variante
JP4006058B2 (ja) *	1997-03-11	2007-11-14	第一三共株式会社	多臓器不全予防及び／又は治療剤
GB0110430D0 (en) *	2001-04-27	2001-06-20	Medical Res Council	Protein variants and uses thereof

2001
- 2001-04-27 GB GBGB0110430.6A patent/GB0110430D0/en not_active Ceased
2002
- 2002-04-29 DK DK02720271T patent/DK1381681T3/da active
- 2002-04-29 AT AT02720271T patent/ATE368741T1/de not_active IP Right Cessation
- 2002-04-29 EP EP02720271A patent/EP1381681B1/de not_active Expired - Lifetime
- 2002-04-29 JP JP2002585635A patent/JP4637452B2/ja not_active Expired - Fee Related
- 2002-04-29 WO PCT/GB2002/001941 patent/WO2002088354A1/en not_active Ceased
- 2002-04-29 US US10/475,616 patent/US7179786B2/en not_active Expired - Fee Related
- 2002-04-29 ES ES02720271T patent/ES2291460T3/es not_active Expired - Lifetime
- 2002-04-29 AU AU2002251337A patent/AU2002251337B2/en not_active Ceased
- 2002-04-29 CA CA2440775A patent/CA2440775C/en not_active Expired - Fee Related
- 2002-04-29 DE DE60221510T patent/DE60221510T2/de not_active Expired - Lifetime
2007
- 2007-01-26 US US11/627,761 patent/US7795214B2/en not_active Expired - Fee Related
2010
- 2010-08-17 US US12/858,189 patent/US8232258B2/en not_active Expired - Fee Related
- 2010-09-17 JP JP2010208693A patent/JP2011045370A/ja active Pending

Also Published As

Publication number	Publication date
US7179786B2 (en)	2007-02-20
CA2440775C (en)	2013-02-26
GB0110430D0 (en)	2001-06-20
DK1381681T3 (da)	2007-10-29
JP2004532032A (ja)	2004-10-21
US20110021612A1 (en)	2011-01-27
EP1381681B1 (de)	2007-08-01
ES2291460T3 (es)	2008-03-01
CA2440775A1 (en)	2002-11-07
JP2011045370A (ja)	2011-03-10
WO2002088354A1 (en)	2002-11-07
AU2002251337B2 (en)	2007-08-02
US8232258B2 (en)	2012-07-31
US20040236073A1 (en)	2004-11-25
EP1381681A1 (de)	2004-01-21
US7795214B2 (en)	2010-09-14
DE60221510T2 (de)	2008-04-17
JP4637452B2 (ja)	2011-02-23
DE60221510D1 (de)	2007-09-13
US20080167224A1 (en)	2008-07-10

Publication	Publication Date	Title
ATE368741T1 (de)	2007-08-15	Das nk1 fragment des hepatocytwachstumfaktors/dispersionsfaktors (hgf/sf), varianten davon und deren verwendung
TR200100267T2 (tr)	2001-09-21	İkameli anilid bileşimleri ve yöntemler.
DK1091975T3 (da)	2006-04-18	Ny cyclosporin med forbedret aktivitetsprofil
DE69916591T2 (de)	2005-04-21	Hochzähe, hochfeste amorphe zirkoniumlegierung
EE200300307A (et)	2003-10-15	1,5-bensotiasepiinid ja nende kasutamine antilipideemiliste vahenditena
DE60039515D1 (de)	2008-08-28	Zusammensetzung für ersatz für knochentransplantat
PL375874A1 (pl)	2005-12-12	Wodne kompozycje farmaceutyczne 2,6-diizopropylofenolu
TR200103233T2 (tr)	2002-04-22	Antikolinerjik etkili bileşik ve ß-mimetikler bazında yeni ilaç bileşimleri.
TR200101772T2 (tr)	2002-04-22	IL-8 Reseptörü antagonistleri olarak hidroksi difenil üre sülfonamidler
NO20005668D0 (no)	2000-11-10	Forbindelser med veksthormonfrigjörende egenskaper
DE69916828D1 (de)	2004-06-03	Pyrazoline, ihre herstellung und verwendung als medikamente
DE60038922D1 (de)	2008-07-03	Zusammensetzungen für den wiederaufbau von knochengewebe
MA25527A1 (fr)	2002-10-01	Composition d'encollage.
ATE272628T1 (de)	2004-08-15	Substituierte gamma-phenyl-delta-lactone und deren analoge, und ihre verwendungen
DE59903261D1 (de)	2002-12-05	Regulierstreckwerk
DE60021903D1 (de)	2005-09-15	Verwendung von zusammensetzungen zur textilpflege
PT1321135E (pt)	2006-09-29	Composicao para o tigimento de oxidacao das fibras ceratinicas
TW200733961A (en)	2007-09-16	Diaryl urea for treating pulmonary hypertension
BR0012327A (pt)	2002-07-02	Pirrolidinas e piperidinas neurotróficas, e composições e métodos relacionados
SE9904404L (sv)	2000-12-23	Ny komposition
DK1100824T3 (da)	2011-06-20	Forbindelser med væksthormonfrigivende egenskaber
DE60015187D1 (de)	2004-11-25	Urotensin-ii rezeptorantagonisten
BR9811694A (pt)	2000-09-26	Forno de cúpula.
EP1096927A4 (de)	2002-09-04	Zusammensetzung für stressbehandlung
DE50010676D1 (de)	2005-08-11	Sequenzvarianten des menschlichen beta-1-adrenozeptorgens und ihre verwendung

Legal Events

Date	Code	Title	Description
2008-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties