ATE362361T1 - Verfahren zur behandlung vaskulärer kopfschmerzen - Google Patents
Verfahren zur behandlung vaskulärer kopfschmerzenInfo
- Publication number
- ATE362361T1 ATE362361T1 AT95942443T AT95942443T ATE362361T1 AT E362361 T1 ATE362361 T1 AT E362361T1 AT 95942443 T AT95942443 T AT 95942443T AT 95942443 T AT95942443 T AT 95942443T AT E362361 T1 ATE362361 T1 AT E362361T1
- Authority
- AT
- Austria
- Prior art keywords
- treating vascular
- vascular headaches
- migraine headache
- treating
- headaches
- Prior art date
Links
- 208000001407 Vascular Headaches Diseases 0.000 title 1
- 208000019695 Migraine disease Diseases 0.000 abstract 2
- 206010027599 migraine Diseases 0.000 abstract 2
- 102000004300 GABA-A Receptors Human genes 0.000 abstract 1
- 108090000839 GABA-A Receptors Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Noodles (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/342,090 US5767117A (en) | 1994-11-18 | 1994-11-18 | Method for treating vascular headaches |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE362361T1 true ATE362361T1 (de) | 2007-06-15 |
Family
ID=23340286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95942443T ATE362361T1 (de) | 1994-11-18 | 1995-11-17 | Verfahren zur behandlung vaskulärer kopfschmerzen |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5767117A (de) |
| EP (2) | EP1839657A3 (de) |
| JP (2) | JPH10509178A (de) |
| AT (1) | ATE362361T1 (de) |
| CA (1) | CA2205134C (de) |
| DE (1) | DE69535498T2 (de) |
| DK (1) | DK0789567T3 (de) |
| ES (1) | ES2289745T3 (de) |
| PT (1) | PT789567E (de) |
| WO (1) | WO1996015782A1 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0934061B3 (de) | 1996-07-24 | 2015-01-21 | Warner-Lambert Company LLC | Isobutylgaba und dessen derivate zur schmerzbehandlung |
| US5914333A (en) * | 1996-07-31 | 1999-06-22 | Novo Nordisk A/S | Treatment of psychotic disorders |
| WO1998005337A1 (en) * | 1996-08-01 | 1998-02-12 | Cocensys, Inc. | Use of gaba and nmda receptor ligands for the treatment of migraine headache |
| US6787530B1 (en) | 1996-08-23 | 2004-09-07 | Monash University | Use of pregnane-diones as analgesic agents |
| US6284794B1 (en) | 1996-11-05 | 2001-09-04 | Head Explorer Aps | Method for treating tension-type headache with inhibitors of nitric oxide and nitric oxide synthase |
| EP1132082A1 (de) * | 1996-11-05 | 2001-09-12 | Head Explorer ApS | Verwendung von Substanzen, die die Produktion von Glutamat hemmen, zur Behandlung von Spannungskopfschmerzen |
| JP2002533353A (ja) * | 1998-12-23 | 2002-10-08 | シトスキャン サイエンシズ エルエルシー | 中枢及び末梢神経系疾患の治療のための組成物、スクリーニング方法及び治療方法 |
| EP1124416A1 (de) * | 1999-03-15 | 2001-08-22 | John Claude Krusz | Behandlung von akuten kopfschmerzem und chronischem schmerz durch verwendung von subanästhetischen dosierungen von schnell entlasteten anästhetischen arzneimitteln |
| GB9906130D0 (en) * | 1999-03-18 | 1999-05-12 | Knoll Ag | Compounds for use in therapy |
| EP1181012B1 (de) * | 1999-05-04 | 2004-09-15 | Keith R. Edwards | Intravenösen verabreichung von valproat zur behandlung von migränekopfschmerzen |
| US6333345B1 (en) * | 1999-05-14 | 2001-12-25 | Sepracor, Inc. | Methods of using and compositions comprising N-desmethylzolpidem |
| HUP0202253A3 (en) * | 1999-07-06 | 2003-12-29 | Lilly Co Eli | Selective iglur5 receptor antagonists for the treatment of migraine |
| AU2574801A (en) | 1999-12-22 | 2001-07-03 | Eli Lilly And Company | Selective iGLUR5 receptor antagonists |
| US6362234B1 (en) * | 2000-08-15 | 2002-03-26 | Vyrex Corporation | Water-soluble prodrugs of propofol for treatment of migrane |
| US20020072509A1 (en) * | 2000-10-11 | 2002-06-13 | Stein Donald Gerald | Methods for the treatment of a traumatic central nervous system injury |
| AU2002228736A1 (en) * | 2001-01-05 | 2002-07-16 | Eli Lilly And Company | Pyrrolidinylmethyl substituted decahydroisoquinolines as excitatory amino acid receptor antagonists |
| US6924294B2 (en) * | 2001-01-05 | 2005-08-02 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| EP1351951A2 (de) * | 2001-01-05 | 2003-10-15 | Eli Lilly And Company | Pyrrolidinylmethyl- und piperidinyl-substituierte decahydroisochinoline als antagonisten von exzitatorischen aminosäurerezeptoren |
| US7205313B2 (en) | 2001-01-05 | 2007-04-17 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| US7090830B2 (en) | 2001-05-24 | 2006-08-15 | Alexza Pharmaceuticals, Inc. | Drug condensation aerosols and kits |
| CA2446904A1 (en) | 2001-05-24 | 2003-04-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
| US7766013B2 (en) | 2001-06-05 | 2010-08-03 | Alexza Pharmaceuticals, Inc. | Aerosol generating method and device |
| US7645442B2 (en) | 2001-05-24 | 2010-01-12 | Alexza Pharmaceuticals, Inc. | Rapid-heating drug delivery article and method of use |
| ES2316571T3 (es) * | 2001-05-24 | 2009-04-16 | Alexza Pharmaceuticals, Inc. | Administracion de alprazolam, estazolam, midazolam o triazolam a traves de una via inhalatoria. |
| US7458374B2 (en) | 2002-05-13 | 2008-12-02 | Alexza Pharmaceuticals, Inc. | Method and apparatus for vaporizing a compound |
| US20070122353A1 (en) | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
| US7585493B2 (en) | 2001-05-24 | 2009-09-08 | Alexza Pharmaceuticals, Inc. | Thin-film drug delivery article and method of use |
| US7498019B2 (en) | 2001-05-24 | 2009-03-03 | Alexza Pharmaceuticals, Inc. | Delivery of compounds for the treatment of headache through an inhalation route |
| US6805853B2 (en) * | 2001-11-09 | 2004-10-19 | Alexza Molecular Delivery Corporation | Delivery of diazepam through an inhalation route |
| WO2002094242A1 (en) * | 2001-05-24 | 2002-11-28 | Alexza Molecular Delivery Corporation | Delivery of rizatriptan or zolmitriptan through an inhalation route |
| KR20040018434A (ko) * | 2001-07-09 | 2004-03-03 | 야마노우치세이야쿠 가부시키가이샤 | 서방성 주사제용 조성물 및 이의 제조방법 |
| US20030045541A1 (en) * | 2001-07-23 | 2003-03-06 | Christopher Bruckner | GABA-Receptor modulators with NMDA-Antagonistic activity |
| SE0104423D0 (sv) | 2001-12-27 | 2001-12-27 | Umecrine Ab | Pregnane steroids and their use in the treatment of CNS disorders |
| US20050176068A1 (en) * | 2002-04-26 | 2005-08-11 | Emmert-Buck Michael R. | Direct cell target analysis |
| WO2003091243A1 (en) | 2002-04-26 | 2003-11-06 | Eli Lilly And Company | Ester derivatives of a decahydroisoquinoline-3-carboxylic acid as analgestics |
| US20040105818A1 (en) | 2002-11-26 | 2004-06-03 | Alexza Molecular Delivery Corporation | Diuretic aerosols and methods of making and using them |
| US7913688B2 (en) | 2002-11-27 | 2011-03-29 | Alexza Pharmaceuticals, Inc. | Inhalation device for producing a drug aerosol |
| US20040204443A1 (en) * | 2003-01-27 | 2004-10-14 | Arthur Zaks | Method for inducing pain relief using imidazo[1,2-a]pyridine derivatives |
| US20040241100A1 (en) * | 2003-03-17 | 2004-12-02 | Fabre Kramer Pharmaceutical, Inc. | Nasally administrable compositions of zolpidem and methods of use |
| WO2004104490A1 (en) | 2003-05-21 | 2004-12-02 | Alexza Pharmaceuticals, Inc. | Self-contained heating unit and drug-supply unit employing same |
| WO2004105862A2 (en) * | 2003-05-28 | 2004-12-09 | The Ohio State University | Measuring human heart muscle viability using myocardial electrical impedance |
| US20050070524A1 (en) * | 2003-06-06 | 2005-03-31 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and an anticonvulsant agent for the treatment of central nervous system disorders |
| US7540286B2 (en) | 2004-06-03 | 2009-06-02 | Alexza Pharmaceuticals, Inc. | Multiple dose condensation aerosol devices and methods of forming condensation aerosols |
| AU2004322756B2 (en) | 2004-08-12 | 2011-04-14 | Alexza Pharmaceuticals, Inc. | Aerosol drug delivery device incorporating percussively activated heat packages |
| CA2900876A1 (en) * | 2004-12-22 | 2006-08-17 | Bhi Limited Partnership | Methods and compositions for treating amyloid-related diseases |
| PL2030622T3 (pl) * | 2005-03-24 | 2011-07-29 | Univ Emory | Wskazanie dawkowania progesteronu w leczeniu urazowego uszkodzenia mózgu |
| US7473687B2 (en) * | 2005-03-24 | 2009-01-06 | Emory University | Methods for the treatment of a traumatic central nervous system injury |
| US20070087055A1 (en) * | 2005-10-14 | 2007-04-19 | David Jan | Directly compressible extended release alprazolam formulation |
| US20070203216A1 (en) * | 2006-02-14 | 2007-08-30 | Bjarke Ebert | Method of treating inflammatory diseases |
| PL3851447T3 (pl) | 2006-10-12 | 2024-03-04 | Bellus Health Inc. | Sposoby, związki, kompozycje i nośniki dostarczające kwas 3-amino-1-propanosulfonowy |
| US20080139510A1 (en) * | 2006-12-07 | 2008-06-12 | Abe Rose | Treatment of migraine headaches with sublingual amino acids |
| US20080216828A1 (en) | 2007-03-09 | 2008-09-11 | Alexza Pharmaceuticals, Inc. | Heating unit for use in a drug delivery device |
| RU2485949C2 (ru) * | 2007-04-11 | 2013-06-27 | Фармасьютикал Продакшнс Инк | Таблетка мелатонина и способы изготовления и применения |
| US12214118B2 (en) | 2018-02-02 | 2025-02-04 | Alexza Pharmaceuticals, Inc. | Electrical condensation aerosol device |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US35517A (en) * | 1862-06-10 | Improved sofa, convertible into a table, trunk, cot | ||
| JPS6019713A (ja) * | 1983-07-13 | 1985-01-31 | Yakurigaku Chuo Kenkyusho:Kk | γ−アミノ酪酸又はその誘導体を主有効成分として含有する血管性頭痛及び二日酔治療薬 |
| US5189064A (en) * | 1985-07-22 | 1993-02-23 | Matrix Technologies, Inc. | Treatment of cocaine addiction |
| US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
| US5120723A (en) * | 1987-08-25 | 1992-06-09 | University Of Southern California | Method, compositions, and compounds for modulating brain excitability |
| DK0808325T3 (da) * | 1994-11-23 | 2001-01-29 | Cocensys Inc | Androstan- og pregnanserier til allosterisk modulering af GABA-receptor |
-
1994
- 1994-11-18 US US08/342,090 patent/US5767117A/en not_active Expired - Fee Related
-
1995
- 1995-11-17 ES ES95942443T patent/ES2289745T3/es not_active Expired - Lifetime
- 1995-11-17 JP JP8517015A patent/JPH10509178A/ja active Pending
- 1995-11-17 DE DE69535498T patent/DE69535498T2/de not_active Expired - Fee Related
- 1995-11-17 PT PT95942443T patent/PT789567E/pt unknown
- 1995-11-17 CA CA002205134A patent/CA2205134C/en not_active Expired - Fee Related
- 1995-11-17 EP EP07009614A patent/EP1839657A3/de not_active Withdrawn
- 1995-11-17 WO PCT/US1995/015070 patent/WO1996015782A1/en not_active Ceased
- 1995-11-17 DK DK95942443T patent/DK0789567T3/da active
- 1995-11-17 AT AT95942443T patent/ATE362361T1/de not_active IP Right Cessation
- 1995-11-17 EP EP95942443A patent/EP0789567B1/de not_active Expired - Lifetime
-
1998
- 1998-01-26 US US09/013,390 patent/US5929061A/en not_active Expired - Fee Related
-
2007
- 2007-08-16 JP JP2007212456A patent/JP2007291143A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10509178A (ja) | 1998-09-08 |
| DK0789567T3 (da) | 2007-09-24 |
| EP1839657A2 (de) | 2007-10-03 |
| PT789567E (pt) | 2007-08-24 |
| EP0789567A1 (de) | 1997-08-20 |
| EP1839657A3 (de) | 2007-12-19 |
| DE69535498T2 (de) | 2008-01-24 |
| ES2289745T3 (es) | 2008-02-01 |
| EP0789567A4 (de) | 1999-01-13 |
| WO1996015782A1 (en) | 1996-05-30 |
| US5767117A (en) | 1998-06-16 |
| CA2205134A1 (en) | 1996-05-30 |
| US5929061A (en) | 1999-07-27 |
| CA2205134C (en) | 2008-08-19 |
| JP2007291143A (ja) | 2007-11-08 |
| DE69535498D1 (de) | 2007-06-28 |
| EP0789567B1 (de) | 2007-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0789567 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |