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ATE228863T1 - METHOD FOR SURFACE COATING MEDICAL IMPLANTS - Google Patents

METHOD FOR SURFACE COATING MEDICAL IMPLANTS

Info

Publication number
ATE228863T1
ATE228863T1 AT99118883T AT99118883T ATE228863T1 AT E228863 T1 ATE228863 T1 AT E228863T1 AT 99118883 T AT99118883 T AT 99118883T AT 99118883 T AT99118883 T AT 99118883T AT E228863 T1 ATE228863 T1 AT E228863T1
Authority
AT
Austria
Prior art keywords
rotation
prosthesis
planes
right angles
surface coating
Prior art date
Application number
AT99118883T
Other languages
German (de)
Inventor
Horst Dr Laube
Erika Nickel
Martin Bei Scheffen Matthaeus
Helmut Willenbockel
Original Assignee
Co Don Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Co Don Ag filed Critical Co Don Ag
Priority claimed from AU60622/99A external-priority patent/AU766234B2/en
Application granted granted Critical
Publication of ATE228863T1 publication Critical patent/ATE228863T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/062—Apparatus for the production of blood vessels made from natural tissue or with layers of living cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Heart valve prosthesis coated prior to implantation by agitation within a cell culture container rotated simultaneously through two axes at right angles to each other, minimizing probability of rejection. A process coats the surface of a prosthesis with living cells prior to medical implantation. The cells are held in a nutritional physiological fluid within a closed container holding the prosthesis in a fixed position. The container with contents is then agitated by rotation through two planes at approx. right angles to each other. The rotation may be continuous or intermittent, or a combination of both, in the two planes. The rotation in each plane may be of uniform or different duration.
AT99118883T 1998-07-30 1999-09-24 METHOD FOR SURFACE COATING MEDICAL IMPLANTS ATE228863T1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19834396A DE19834396C2 (en) 1998-07-30 1998-07-30 Process for the surface coating of medical implants
EP99118883A EP1086710B1 (en) 1998-07-30 1999-09-24 Method for coating medical implants
US09/432,497 US6214407B1 (en) 1998-07-30 1999-11-02 Method of surface coating medical implants
CA002288532A CA2288532A1 (en) 1998-07-30 1999-11-04 Method of seeding cells onto the surface of medical implants
AU60622/99A AU766234B2 (en) 1999-11-24 1999-11-24 Method of surface coating medical implants

Publications (1)

Publication Number Publication Date
ATE228863T1 true ATE228863T1 (en) 2002-12-15

Family

ID=27507113

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99118883T ATE228863T1 (en) 1998-07-30 1999-09-24 METHOD FOR SURFACE COATING MEDICAL IMPLANTS

Country Status (5)

Country Link
US (1) US6214407B1 (en)
EP (1) EP1086710B1 (en)
AT (1) ATE228863T1 (en)
CA (1) CA2288532A1 (en)
DE (2) DE19834396C2 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6776792B1 (en) 1997-04-24 2004-08-17 Advanced Cardiovascular Systems Inc. Coated endovascular stent
DE19834396C2 (en) * 1998-07-30 2000-07-13 Daimlerchrysler Aerospace Ag Process for the surface coating of medical implants
DE19945587A1 (en) 1999-09-23 2001-05-10 Co Don Ag Procedure for inserting implants into human organs
US6592618B2 (en) * 2000-02-29 2003-07-15 The Brigham And Women's Hospital, Inc. In vitro modification of cardiac valvular xenografts
US6395326B1 (en) 2000-05-31 2002-05-28 Advanced Cardiovascular Systems, Inc. Apparatus and method for depositing a coating onto a surface of a prosthesis
US20040211362A1 (en) * 2000-05-31 2004-10-28 Daniel Castro System for coating a stent
US6783793B1 (en) 2000-10-26 2004-08-31 Advanced Cardiovascular Systems, Inc. Selective coating of medical devices
US6565659B1 (en) 2001-06-28 2003-05-20 Advanced Cardiovascular Systems, Inc. Stent mounting assembly and a method of using the same to coat a stent
US20030059520A1 (en) 2001-09-27 2003-03-27 Yung-Ming Chen Apparatus for regulating temperature of a composition and a method of coating implantable devices
US20040261698A1 (en) * 2001-09-27 2004-12-30 Roorda Wouter E. Stent coating apparatus
US7338557B1 (en) * 2002-12-17 2008-03-04 Advanced Cardiovascular Systems, Inc. Nozzle for use in coating a stent
DE10260961A1 (en) * 2002-12-20 2004-07-01 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Semiconductor sensor with contact on the front
US7087115B1 (en) * 2003-02-13 2006-08-08 Advanced Cardiovascular Systems, Inc. Nozzle and method for use in coating a stent
WO2005000001A2 (en) * 2003-06-20 2005-01-06 University Of Colorado Surgical cannula
US7341630B1 (en) * 2003-06-26 2008-03-11 Advanced Cardiovascular Systems, Inc. Stent coating system
DE10337137A1 (en) * 2003-08-11 2005-03-24 Kc - Kunststoff-Chemische Produkte Gmbh Method for partially coating printed circuit boards and apparatus for carrying out the method
US7198675B2 (en) 2003-09-30 2007-04-03 Advanced Cardiovascular Systems Stent mandrel fixture and method for selectively coating surfaces of a stent
US7563324B1 (en) 2003-12-29 2009-07-21 Advanced Cardiovascular Systems Inc. System and method for coating an implantable medical device
US7553377B1 (en) 2004-04-27 2009-06-30 Advanced Cardiovascular Systems, Inc. Apparatus and method for electrostatic coating of an abluminal stent surface
US7585369B2 (en) * 2004-08-04 2009-09-08 Larson Marian L Apparatus for coating medical devices
US7588642B1 (en) 2004-11-29 2009-09-15 Advanced Cardiovascular Systems, Inc. Abluminal stent coating apparatus and method using a brush assembly
US7632307B2 (en) 2004-12-16 2009-12-15 Advanced Cardiovascular Systems, Inc. Abluminal, multilayer coating constructs for drug-delivery stents
US20060199265A1 (en) * 2005-03-02 2006-09-07 Wolf Michael F Seeding implantable medical devices with cells
US7867547B2 (en) 2005-12-19 2011-01-11 Advanced Cardiovascular Systems, Inc. Selectively coating luminal surfaces of stents
US8069814B2 (en) 2006-05-04 2011-12-06 Advanced Cardiovascular Systems, Inc. Stent support devices
US8603530B2 (en) 2006-06-14 2013-12-10 Abbott Cardiovascular Systems Inc. Nanoshell therapy
US8048448B2 (en) 2006-06-15 2011-11-01 Abbott Cardiovascular Systems Inc. Nanoshells for drug delivery
US8017237B2 (en) 2006-06-23 2011-09-13 Abbott Cardiovascular Systems, Inc. Nanoshells on polymers
US8048441B2 (en) 2007-06-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Nanobead releasing medical devices
KR101587522B1 (en) 2007-11-14 2016-01-21 바이오센서스 인터내셔널 그룹, 리미티드 Automated Coating Apparatus and Method
US20130216719A1 (en) * 2010-10-27 2013-08-22 Envision Scientific Private Limited Method and system for coating substrates
WO2013040544A2 (en) 2011-09-15 2013-03-21 Cornell University Biomedical implant for use in fluid shear stress environments

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5441539A (en) * 1985-06-06 1995-08-15 Thomas Jefferson University Endothelial cell deposition device
CH675679A5 (en) * 1987-12-07 1990-10-31 Sulzer Ag
CH676195A5 (en) * 1988-10-07 1990-12-28 Sulzer Ag
US5205867A (en) * 1989-08-21 1993-04-27 At&T Bell Laboratories Spin coating apparatus having a horizontally linearly movable wafer holder
DE59104369D1 (en) * 1990-06-15 1995-03-09 Sulzer Medizinaltechnik Ag Process for the production of porous, tubular prostheses made of plastic loaded with living cells.
GB9116036D0 (en) * 1991-07-25 1991-09-11 Univ Leicester Preparing grafts for implantation
AU665813B2 (en) * 1992-05-11 1996-01-18 Sulzer Medizinaltechnik Ag Process and apparatus for producing endoprostheses
CH683747A5 (en) * 1992-12-29 1994-05-13 Sulzer Medizinaltechnik Ag Blood and lymph vessel prosthesis - has living cells applied to shaped carrier material, with cell-protecting agent
CA2161863A1 (en) * 1995-10-31 1997-05-01 Michael Vivian Sefton Angiogenic material and uses thereof
US6060129A (en) * 1996-03-04 2000-05-09 Polar Materials, Inc. Method for bulk coating using a plasma process
ES2210526T3 (en) * 1996-06-04 2004-07-01 Centerpulse Biologics Inc. CARTILAGO PRODUCTION PROCEDURE.
DE19834396C2 (en) * 1998-07-30 2000-07-13 Daimlerchrysler Aerospace Ag Process for the surface coating of medical implants
DE19915610A1 (en) * 1999-04-07 2000-10-19 Augustinus Bader Process for colonization of substrates with biological cells and colonization devices that can be used for this

Also Published As

Publication number Publication date
CA2288532A1 (en) 2001-05-04
EP1086710B1 (en) 2002-12-04
US6214407B1 (en) 2001-04-10
DE19834396A1 (en) 2000-02-03
DE19834396C2 (en) 2000-07-13
DE59903659D1 (en) 2003-01-16
EP1086710A1 (en) 2001-03-28

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