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ATE299490T1 - Multizyklische verbindungen zur hemmung der durch vla-4 vermittelten leukozytenadhäsion - Google Patents

Multizyklische verbindungen zur hemmung der durch vla-4 vermittelten leukozytenadhäsion

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Publication number
ATE299490T1
ATE299490T1 AT00911619T AT00911619T ATE299490T1 AT E299490 T1 ATE299490 T1 AT E299490T1 AT 00911619 T AT00911619 T AT 00911619T AT 00911619 T AT00911619 T AT 00911619T AT E299490 T1 ATE299490 T1 AT E299490T1
Authority
AT
Austria
Prior art keywords
leukocyte adhesion
mediated leukocyte
multicyclic compounds
inhibiting vla
vla
Prior art date
Application number
AT00911619T
Other languages
English (en)
Inventor
Francine S Grant
Bradley S Johnson
Michael A Pleiss
Eugene D Thorsett
Original Assignee
Elan Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharm Inc filed Critical Elan Pharm Inc
Application granted granted Critical
Publication of ATE299490T1 publication Critical patent/ATE299490T1/de

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    • C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/84—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a saturated carbon skeleton containing rings
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AT00911619T 1999-01-22 2000-01-21 Multizyklische verbindungen zur hemmung der durch vla-4 vermittelten leukozytenadhäsion ATE299490T1 (de)

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