ATE28401T1 - Naphthalen- oder azanaphthalencarbonsaeureamide als arzneimittel, naphthalen- oder azanaphthalencarbonsaeureamidderivate und verfahren zu ihrer herstellung. - Google Patents
Naphthalen- oder azanaphthalencarbonsaeureamide als arzneimittel, naphthalen- oder azanaphthalencarbonsaeureamidderivate und verfahren zu ihrer herstellung.Info
- Publication number
- ATE28401T1 ATE28401T1 AT83402501T AT83402501T ATE28401T1 AT E28401 T1 ATE28401 T1 AT E28401T1 AT 83402501 T AT83402501 T AT 83402501T AT 83402501 T AT83402501 T AT 83402501T AT E28401 T1 ATE28401 T1 AT E28401T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- carbonic
- azanaphthalen
- azanaphthalene
- naphthalenic
- Prior art date
Links
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 title 2
- 150000004649 carbonic acid derivatives Chemical class 0.000 title 1
- 150000004653 carbonic acids Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000000437 thiazol-2-yl group Chemical group [H]C1=C([H])N=C(*)S1 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8221758A FR2538388B1 (fr) | 1982-12-24 | 1982-12-24 | Nouveaux derives de naphtalene- ou azanaphtalenecarboxamide, leurs procedes de preparation et leur utilisation comme medicaments |
| EP83402501A EP0112776B1 (de) | 1982-12-24 | 1983-12-21 | Naphthalen- oder Azanaphthalencarbonsäureamide als Arzneimittel, Naphthalen- oder Azanaphthalencarbonsäureamidderivate und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE28401T1 true ATE28401T1 (de) | 1987-08-15 |
Family
ID=9280501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83402501T ATE28401T1 (de) | 1982-12-24 | 1983-12-21 | Naphthalen- oder azanaphthalencarbonsaeureamide als arzneimittel, naphthalen- oder azanaphthalencarbonsaeureamidderivate und verfahren zu ihrer herstellung. |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4711890A (de) |
| EP (1) | EP0112776B1 (de) |
| JP (1) | JPS59219260A (de) |
| AT (1) | ATE28401T1 (de) |
| AU (1) | AU575797B2 (de) |
| CA (1) | CA1225992A (de) |
| DE (1) | DE3372579D1 (de) |
| DK (1) | DK596483A (de) |
| ES (1) | ES8502433A1 (de) |
| FR (1) | FR2538388B1 (de) |
| GR (1) | GR82358B (de) |
| HU (1) | HU191745B (de) |
| IL (1) | IL70528A (de) |
| MA (1) | MA19982A1 (de) |
| NO (1) | NO834798L (de) |
| PT (1) | PT77886B (de) |
| SU (1) | SU1255050A3 (de) |
| ZA (1) | ZA839576B (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4639454A (en) * | 1985-01-17 | 1987-01-27 | E. I. Du Pont De Nemours And Company | Phenylquinazolinecarboxylic acids and derivatives as cancer chemotherapeutic agents |
| FR2582514B1 (fr) * | 1985-05-30 | 1988-02-19 | Rhone Poulenc Sante | Medicaments a base d'amides, nouveaux amides et leur preparation |
| DK623586A (da) * | 1985-12-27 | 1987-06-28 | Eisai Co Ltd | Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne |
| FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| US4933447A (en) * | 1987-09-24 | 1990-06-12 | Ss Pharmaceutical Co., Ltd. | Quinoline derivatives |
| ITMI941099A1 (it) * | 1994-05-27 | 1995-11-27 | Smithkline Beecham Farma | Derivati chinolinici |
| SK282721B6 (sk) * | 1994-05-27 | 2002-11-06 | Smithkline Beecham S.P.A. | Nepeptidové NK3 antagonistické látky, spôsob ich výroby, farmaceutické prostriedky s ich obsahom a ich použitie |
| IT1270615B (it) * | 1994-07-14 | 1997-05-07 | Smithkline Beecham Farma | Uso di derivati di chinolina |
| US5703096A (en) * | 1994-10-07 | 1997-12-30 | Sankyo Company, Limited | Oxime derivatives, their preparation and their therapeutic use |
| US5627193A (en) * | 1995-02-09 | 1997-05-06 | Mitsui Toatsu Chemicals, Inc. | Quinoline-4-carbonylguanidine derivatives, process for producing the same and pharmaceutical preparations containing the compounds |
| GB9524104D0 (en) | 1995-11-24 | 1996-01-24 | Smithkline Beecham Spa | Novel compounds |
| ES2236757T3 (es) * | 1995-11-24 | 2005-07-16 | Glaxosmithkline S.P.A. | Derivados de quinolina. |
| AR004735A1 (es) * | 1995-11-24 | 1999-03-10 | Smithkline Beecham Spa | Quinoleina 4-amido sustituida, un procedimiento para su preparacion, una composicion farmaceutica que los contiene y el uso de los mismos para lapreparacion de un medicamento. |
| KR100225565B1 (ko) * | 1996-12-12 | 1999-10-15 | 유규재 | 초미세 규산 알루미늄염의 제조법 |
| AU7474998A (en) * | 1997-05-07 | 1998-11-27 | Emory University | Haloisoquinoline carboxamide |
| FR2778564B1 (fr) * | 1998-05-13 | 2001-07-13 | Sanofi Sa | Utilisation de composes reduisant l'apoptose |
| WO1999058117A1 (fr) * | 1998-05-13 | 1999-11-18 | Sanofi-Synthelabo | Utilisation de composes reduisant l'apoptose |
| RU2154061C1 (ru) * | 1999-02-09 | 2000-08-10 | Пермская государственная фармацевтическая академия | Анилид 2-оксо-1,2,5,6,7,8-гексагидрохинолин-4-карбоновой кислоты, проявляющий противовоспалительную и анальгетическую активность |
| DE10035927A1 (de) | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
| DE10035928A1 (de) | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
| DE60114227T2 (de) * | 2000-08-16 | 2006-04-20 | Neurogen Corp., Branford | 2,4-substituierte pyridinderivate |
| US20040152727A1 (en) * | 2001-05-18 | 2004-08-05 | Hay Douglas William Pierre | Novel use |
| RU2229475C1 (ru) * | 2003-03-06 | 2004-05-27 | ООО "Исследовательский институт химического разнообразия | 6-сульфамоилхинолин-4-карбоновые кислоты, их производные и комбинаторная библиотека |
| JP2006519846A (ja) * | 2003-03-10 | 2006-08-31 | シェーリング コーポレイション | 複素環式キナーゼインヒビター：使用および合成の方法 |
| WO2008023357A1 (en) * | 2006-08-22 | 2008-02-28 | Technion Research And Development Foundation Ltd. | Heterocyclic derivatives binding to the peripheral-type benzodiazepine receptor (pbr) |
| DE102008015032A1 (de) * | 2008-03-17 | 2009-09-24 | Aicuris Gmbh & Co. Kg | Substituierte Pyrazolamide und ihre Verwendung |
| DE102008015033A1 (de) | 2008-03-17 | 2009-09-24 | Aicuris Gmbh & Co. Kg | Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung |
| DE102008062863A1 (de) | 2008-12-17 | 2010-06-24 | Aicuris Gmbh & Co. Kg | Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung |
| DE102008062878A1 (de) | 2008-12-17 | 2010-06-24 | Aicuris Gmbh & Co. Kg | Substituierte Furancarboxamide und ihre Verwendung |
| EP2907806A1 (de) * | 2014-02-14 | 2015-08-19 | Universita Degli Studi Di Genova | Neue Verbindungen als selektive PDE4D Inhibitoren |
| CN106458933B (zh) | 2014-04-23 | 2021-03-05 | 泰克年研究发展基金会公司 | 基于喹唑啉支架的化合物、其药物组合物及使用方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB191210352A (en) * | 1912-01-16 | 1913-05-01 | Hoechst Ag | Manufacture of New Derivatives of Phenyl-cinchoninic Acid and of Homologues and Derivatives thereof. |
| FR1364605A (fr) * | 1962-03-01 | 1964-06-26 | Procédé de préparation d'amides des acides carboxyliques | |
| US3812127A (en) * | 1966-10-31 | 1974-05-21 | Pfizer | 4-(quinolin-4-yl)piperazine-1-carboxylic acid esters |
| US3799929A (en) * | 1972-03-17 | 1974-03-26 | Lilly Co Eli | Cinchoninic acid derivatives |
| FR2525595A1 (fr) * | 1982-04-27 | 1983-10-28 | Pharmuka Lab | Nouveaux derives d'arene et d'heteroarenecarboxamides et leur utilisation comme medicaments |
-
1982
- 1982-12-24 FR FR8221758A patent/FR2538388B1/fr not_active Expired
-
1983
- 1983-12-21 AT AT83402501T patent/ATE28401T1/de not_active IP Right Cessation
- 1983-12-21 GR GR73304A patent/GR82358B/el unknown
- 1983-12-21 DE DE8383402501T patent/DE3372579D1/de not_active Expired
- 1983-12-21 EP EP83402501A patent/EP0112776B1/de not_active Expired
- 1983-12-22 AU AU22776/83A patent/AU575797B2/en not_active Ceased
- 1983-12-22 ZA ZA839576A patent/ZA839576B/xx unknown
- 1983-12-22 US US06/564,322 patent/US4711890A/en not_active Expired - Fee Related
- 1983-12-22 MA MA20203A patent/MA19982A1/fr unknown
- 1983-12-22 HU HU834425A patent/HU191745B/hu unknown
- 1983-12-22 JP JP58243082A patent/JPS59219260A/ja active Pending
- 1983-12-22 IL IL70528A patent/IL70528A/xx unknown
- 1983-12-23 DK DK596483A patent/DK596483A/da not_active Application Discontinuation
- 1983-12-23 CA CA000444273A patent/CA1225992A/fr not_active Expired
- 1983-12-23 ES ES528364A patent/ES8502433A1/es not_active Expired
- 1983-12-23 PT PT77886A patent/PT77886B/pt not_active IP Right Cessation
- 1983-12-23 NO NO834798A patent/NO834798L/no unknown
- 1983-12-23 SU SU833682598A patent/SU1255050A3/ru active
-
1985
- 1985-08-08 US US06/763,660 patent/US4684652A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| PT77886A (fr) | 1984-01-01 |
| AU575797B2 (en) | 1988-08-11 |
| JPS59219260A (ja) | 1984-12-10 |
| AU2277683A (en) | 1984-06-28 |
| IL70528A0 (en) | 1984-03-30 |
| HU191745B (en) | 1987-04-28 |
| CA1225992A (fr) | 1987-08-25 |
| MA19982A1 (fr) | 1984-07-01 |
| EP0112776B1 (de) | 1987-07-22 |
| DE3372579D1 (en) | 1987-08-27 |
| SU1255050A3 (ru) | 1986-08-30 |
| ES528364A0 (es) | 1985-01-01 |
| ES8502433A1 (es) | 1985-01-01 |
| GR82358B (de) | 1984-12-13 |
| US4711890A (en) | 1987-12-08 |
| EP0112776A3 (en) | 1984-09-12 |
| US4684652A (en) | 1987-08-04 |
| NO834798L (no) | 1984-06-25 |
| EP0112776A2 (de) | 1984-07-04 |
| FR2538388B1 (fr) | 1985-06-21 |
| FR2538388A1 (fr) | 1984-06-29 |
| ZA839576B (en) | 1984-08-29 |
| IL70528A (en) | 1987-01-30 |
| PT77886B (fr) | 1986-04-09 |
| DK596483D0 (da) | 1983-12-23 |
| DK596483A (da) | 1984-06-25 |
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