ATE256119T1 - Verfahren zum nachweis von einer zielsubstanz in einer probe mit hilfe von pyryliumverbindung - Google Patents
Verfahren zum nachweis von einer zielsubstanz in einer probe mit hilfe von pyryliumverbindungInfo
- Publication number
- ATE256119T1 ATE256119T1 AT95303567T AT95303567T ATE256119T1 AT E256119 T1 ATE256119 T1 AT E256119T1 AT 95303567 T AT95303567 T AT 95303567T AT 95303567 T AT95303567 T AT 95303567T AT E256119 T1 ATE256119 T1 AT E256119T1
- Authority
- AT
- Austria
- Prior art keywords
- target substance
- sample
- detecting
- reagents
- interaction
- Prior art date
Links
- 239000013076 target substance Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- -1 PYRYLIUM COMPOUND Chemical class 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 3
- 230000003993 interaction Effects 0.000 abstract 3
- WVIICGIFSIBFOG-UHFFFAOYSA-N pyrylium Chemical class C1=CC=[O+]C=C1 WVIICGIFSIBFOG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11262694A JP3796271B2 (ja) | 1994-05-26 | 1994-05-26 | 試料中の標的物質の検出方法 |
| JP12504094A JP4114958B2 (ja) | 1994-06-07 | 1994-06-07 | 核酸ハイブリッド体の検出方法及びそれに用いるプローブ |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE256119T1 true ATE256119T1 (de) | 2003-12-15 |
Family
ID=26451740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95303567T ATE256119T1 (de) | 1994-05-26 | 1995-05-25 | Verfahren zum nachweis von einer zielsubstanz in einer probe mit hilfe von pyryliumverbindung |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US6156506A (de) |
| EP (1) | EP0684239B1 (de) |
| AT (1) | ATE256119T1 (de) |
| DE (1) | DE69532255D1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0837141B1 (de) * | 1996-10-03 | 2003-01-08 | Canon Kabushiki Kaisha | Verfahren zur Detektion von Zielnukleinsäure, Verfahren zu ihrer Quantifizierung und Pyrylium-Verbindungen zur Chemilumineszenz-Analyse |
| US6960432B2 (en) * | 1999-07-26 | 2005-11-01 | Canon Kabushiki Kaisha | Detection/quantification of targeted nucleotide chains, and detection/quantification of multi-stranded nucleotide chains by fluorescence |
| US7897140B2 (en) | 1999-12-23 | 2011-03-01 | Health Research, Inc. | Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents |
| WO2003077886A1 (en) * | 2002-03-20 | 2003-09-25 | Hosokawa Micron Corporation | Method of manufacturing chemical-containing composite particles |
| US7144950B2 (en) | 2003-09-17 | 2006-12-05 | The Regents Of The University Of California | Conformationally flexible cationic conjugated polymers |
| US10001475B2 (en) | 2002-06-20 | 2018-06-19 | The Regents Of The University Of California | Light harvesting multichromophore compositions and methods of using the same |
| US9371559B2 (en) | 2002-06-20 | 2016-06-21 | The Regents Of The University Of California | Compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
| AU2003248747A1 (en) | 2002-06-27 | 2004-01-19 | Health Research, Inc. | Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy |
| WO2004005289A2 (en) | 2002-07-02 | 2004-01-15 | Health Research, Inc. | Efficient synthesis of pyropheophorbide a and its derivatives |
| EP1549772B1 (de) * | 2002-08-26 | 2013-01-02 | The Regents of The University of California | Verfahren und zusammensetzungen zum nachweis und zur analyse von polynukleotiden unter verwendung von licht einfangenden multichromophoren |
| JP4504821B2 (ja) * | 2002-08-26 | 2010-07-14 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 集光性多発色団を用いてポリヌクレオチドを検出及び分析するための方法並びに組成物 |
| AU2004215006A1 (en) | 2003-02-13 | 2004-09-10 | The Regents Of The University Of California | Methods and compositions for detection and analysis of polynucleotide-binding protein interactions using light harvesting multichromophores |
| JP4458327B2 (ja) * | 2003-08-28 | 2010-04-28 | キヤノン株式会社 | 標的物質の定量方法および該方法に用いるプローブ担体 |
| JP4541731B2 (ja) * | 2004-03-12 | 2010-09-08 | キヤノン株式会社 | 核酸検出方法 |
| US8216610B2 (en) * | 2004-05-28 | 2012-07-10 | Imaginot Pty Ltd. | Oral paracetamol formulations |
| JP4183256B2 (ja) * | 2004-08-04 | 2008-11-19 | キヤノン株式会社 | 核酸増幅反応産物の鎖分離方法、核酸増幅反応産物の検出方法 |
| JP2006094760A (ja) * | 2004-09-29 | 2006-04-13 | Canon Inc | 細胞のスクリーニング方法および口腔癌細胞検出方法 |
| WO2006074471A2 (en) | 2005-01-10 | 2006-07-13 | The Regents Of The University Of California | Cationic conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays |
| US7811755B2 (en) | 2005-01-10 | 2010-10-12 | The Regents Of The University Of California | Methods and articles for strand-specific polynucleotide detection with cationic multichromophores |
| US8535914B2 (en) * | 2005-01-21 | 2013-09-17 | Canon Kabushiki Kaisha | Probe, probe set and information acquisition method using the same |
| WO2006083932A2 (en) | 2005-01-31 | 2006-08-10 | The Regents Of The University | Methods and compositions for aggregant detection |
| JP2007010413A (ja) * | 2005-06-29 | 2007-01-18 | Canon Inc | 核酸ハイブリッドの融点測定方法及びそのための装置 |
| US7642086B2 (en) * | 2005-08-09 | 2010-01-05 | Canon Kabushiki Kaisha | Labeled probe bound object, method for producing the same and method for using the same |
| US9757455B2 (en) | 2005-11-28 | 2017-09-12 | Johnson & Johnson Consumer Inc. | Oral therapeutic compound delivery system |
| US20090011413A1 (en) * | 2005-12-14 | 2009-01-08 | Canon Kabushiki Kaisha | Method for screening colon cancer cells and gene set used for examination of colon cancer |
| JP5729904B2 (ja) | 2009-06-02 | 2015-06-03 | キヤノン株式会社 | 細胞から蛋白質、dna、rnaを調製する方法 |
| MX340373B (es) * | 2010-01-26 | 2016-07-07 | Meiji Seika Pharma Co Ltd * | Estructura de acido nucleico que contiene un agrupamiento de genes para la biosintesis de piripiropeno y un gen marcador. |
| CN113072534B (zh) * | 2021-04-02 | 2022-02-08 | 广西师范大学 | 一种rna荧光探针及其制备方法和应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3786369A (en) * | 1972-12-27 | 1974-01-15 | Eastman Kodak Co | Laser dye composition |
| US4341894A (en) * | 1978-03-13 | 1982-07-27 | Eastman Kodak Company | Sensitizers for photoconductive compositions |
| US4555396A (en) * | 1982-12-22 | 1985-11-26 | Eastman Kodak Company | Use of pyrylium and thiapyrylium compounds as biological stains |
| US4840784A (en) * | 1982-12-22 | 1989-06-20 | Eastman Kodak Company | Use of pyrylium and thiapyrylium compounds as biological stains |
| US4886744A (en) * | 1985-04-25 | 1989-12-12 | Polaroid Corporation | Fluorescent conjugates and biological diagnostic assay system |
| US5011769A (en) * | 1985-12-05 | 1991-04-30 | Meiogenics U.S. Limited Partnership | Methods for detecting nucleic acid sequences |
| CA1273552A (en) * | 1985-12-23 | 1990-09-04 | Michael J. Heller | Fluorescent stokes shift probes for polynucleotide hybridization assays |
| DE3785591T2 (de) * | 1986-01-10 | 1993-09-02 | Amoco Corp | Kompetitiver homogener test. |
| JPS63238166A (ja) * | 1987-03-26 | 1988-10-04 | Mitsubishi Electric Corp | 有機電子素子材料 |
| JPH01153683A (ja) * | 1987-11-06 | 1989-06-15 | Eastman Kodak Co | アミノ置換チオピリリウム化合物 |
| CA1323293C (en) * | 1987-12-11 | 1993-10-19 | Keith C. Backman | Assay using template-dependent nucleic acid probe reorganization |
| US5324829A (en) * | 1988-12-16 | 1994-06-28 | Ortho Diagnostic Systems, Inc. | High specific activity nucleic acid probes having target recognition and signal generating moieties |
| US5229297A (en) * | 1989-02-03 | 1993-07-20 | Eastman Kodak Company | Containment cuvette for PCR and method of use |
| GB8902689D0 (en) * | 1989-02-07 | 1989-03-30 | Ici Plc | Assay method |
| CA2033692A1 (en) * | 1990-01-25 | 1991-07-26 | Wilhelm Bannwarth | Energy transfer systems |
| US5102784A (en) * | 1990-05-04 | 1992-04-07 | Oncor, Inc. | Restriction amplification assay |
| JP2985446B2 (ja) * | 1990-10-31 | 1999-11-29 | 東ソー株式会社 | 核酸の検出及び測定方法 |
| US5994056A (en) * | 1991-05-02 | 1999-11-30 | Roche Molecular Systems, Inc. | Homogeneous methods for nucleic acid amplification and detection |
| EP0567635B1 (de) * | 1991-11-15 | 2000-05-31 | Igen International, Inc. | Schnelle bestimmungsverfahren für amplifikationsprodukte |
| ATE319853T1 (de) * | 1992-11-27 | 2006-03-15 | Canon Kk | Verfahren und sonde zum nachweis von nukleinsäuren |
| JP3247001B2 (ja) * | 1992-12-21 | 2002-01-15 | キヤノン株式会社 | ピリリウム化合物を用いた2本鎖核酸の検出方法、ピリリウム化合物を含有するプローブ及びそれを用いた標的核酸の検出方法、新規ピリリウム化合物 |
| EP0643140B1 (de) * | 1993-09-13 | 2001-10-31 | Canon Kabushiki Kaisha | Bestimmung von Nukleinsäuren durch PCR, Messung der Anzahl von mikrobiellen Zellen, Genen oder Genkopien durch PCR und Kit zu ihrer Verwendung |
| US5591578A (en) * | 1993-12-10 | 1997-01-07 | California Institute Of Technology | Nucleic acid mediated electron transfer |
-
1995
- 1995-05-25 EP EP95303567A patent/EP0684239B1/de not_active Expired - Lifetime
- 1995-05-25 DE DE69532255T patent/DE69532255D1/de not_active Expired - Lifetime
- 1995-05-25 AT AT95303567T patent/ATE256119T1/de not_active IP Right Cessation
-
1997
- 1997-04-01 US US08/825,586 patent/US6156506A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0684239B1 (de) | 2003-12-10 |
| DE69532255D1 (de) | 2004-01-22 |
| US6156506A (en) | 2000-12-05 |
| EP0684239A1 (de) | 1995-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |