ATE250340T1 - 7-methylthiooxomethyl- und 7- methylthiodioxomethyl-paclitaxele - Google Patents
7-methylthiooxomethyl- und 7- methylthiodioxomethyl-paclitaxeleInfo
- Publication number
- ATE250340T1 ATE250340T1 AT98908734T AT98908734T ATE250340T1 AT E250340 T1 ATE250340 T1 AT E250340T1 AT 98908734 T AT98908734 T AT 98908734T AT 98908734 T AT98908734 T AT 98908734T AT E250340 T1 ATE250340 T1 AT E250340T1
- Authority
- AT
- Austria
- Prior art keywords
- paclitaxele
- methylthiooxomethyl
- methylthiodioxomethyl
- present
- invention concerns
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000004579 taxol derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3948097P | 1997-02-28 | 1997-02-28 | |
| PCT/US1998/003741 WO1998037765A1 (en) | 1997-02-28 | 1998-02-24 | 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE250340T1 true ATE250340T1 (de) | 2003-10-15 |
Family
ID=21905699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98908734T ATE250340T1 (de) | 1997-02-28 | 1998-02-24 | 7-methylthiooxomethyl- und 7- methylthiodioxomethyl-paclitaxele |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5902822A (de) |
| EP (1) | EP1011329B1 (de) |
| JP (1) | JP2001513778A (de) |
| AT (1) | ATE250340T1 (de) |
| AU (1) | AU724591B2 (de) |
| CA (1) | CA2282264A1 (de) |
| DE (1) | DE69818492T2 (de) |
| DK (1) | DK1011329T3 (de) |
| ES (1) | ES2207817T3 (de) |
| PT (1) | PT1011329E (de) |
| WO (1) | WO1998037765A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999046904A1 (en) * | 1998-03-12 | 1999-09-16 | John Griffits | Improved realtime internet functions by use of a hybrid pstn and ip protocol means |
| WO2001024763A2 (en) | 1999-10-01 | 2001-04-12 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| AU7007001A (en) | 2000-06-22 | 2002-01-02 | Nitromed Inc | Nitrosated and nitrosylated taxanes, compositions and methods of use |
| PL217731B1 (pl) | 2006-06-01 | 2014-08-29 | Tomasz Byrski | Sposób wykrywania genetycznie uwarunkowanej obniżonej odpowiedzi na chemioterapię cytostatykiem taksanowym, zastosowanie mutacji założycielskiej oraz zestawu do wykrywania takiej odpowiedzi |
| EP3007692A1 (de) | 2013-06-11 | 2016-04-20 | Bayer Pharma Aktiengesellschaft | Kombinationen zur behandlung von krebs mit einem mps-1-kinaseinhibitor und einem mitotischen inhibitor |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| US4960790A (en) * | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
| EP0642503B1 (de) * | 1991-09-23 | 1999-12-01 | Florida State University | 10-disacetoxytaxolderivate |
| US5272171A (en) * | 1992-02-13 | 1993-12-21 | Bristol-Myers Squibb Company | Phosphonooxy and carbonate derivatives of taxol |
| DE69325454T2 (de) * | 1992-04-17 | 2000-01-20 | Abbott Laboratories, Abbott Park | Taxol-derivate |
| US5254580A (en) * | 1993-01-19 | 1993-10-19 | Bristol-Myers Squibb Company | 7,8-cyclopropataxanes |
| US5294637A (en) * | 1992-07-01 | 1994-03-15 | Bristol-Myers Squibb Company | Fluoro taxols |
| CA2100808A1 (en) * | 1992-10-01 | 1994-04-02 | Vittorio Farina | Deoxy paclitaxels |
| FR2697019B1 (fr) * | 1992-10-15 | 1994-11-25 | Rhone Poulenc Rorer Sa | Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent. |
| CA2109861C (en) * | 1992-12-04 | 1999-03-16 | Shu-Hui Chen | 6,7-modified paclitaxels |
| AU679206B2 (en) * | 1992-12-23 | 1997-06-26 | Bristol-Myers Squibb Company | Novel sidechain-bearing taxanes and intermediates thereof |
| US5646176A (en) * | 1992-12-24 | 1997-07-08 | Bristol-Myers Squibb Company | Phosphonooxymethyl ethers of taxane derivatives |
| CA2111527C (en) * | 1992-12-24 | 2000-07-18 | Jerzy Golik | Phosphonooxymethyl ethers of taxane derivatives |
| EP0687260B1 (de) * | 1993-03-05 | 2003-02-19 | Florida State University | Verfahren zur Herstellung von 9-Desoxotaxanen |
| US5703247A (en) * | 1993-03-11 | 1997-12-30 | Virginia Tech Intellectual Properties, Inc. | 2-Debenzoyl-2-acyl taxol derivatives and methods for making same |
| IL127598A (en) * | 1994-01-28 | 2003-04-10 | Upjohn Co | Process for preparing isotaxol analogs |
| CA2192373A1 (en) * | 1994-06-09 | 1995-12-14 | Hirofumi Terasawa | Deacetoxytaxol derivative |
| WO1996000724A1 (en) * | 1994-06-28 | 1996-01-11 | Pharmacia & Upjohn Company | 7-ether-taxol analogs, antineoplastic use and pharmaceutical compositions containing them |
| CN1073105C (zh) * | 1994-07-26 | 2001-10-17 | 因迪纳有限公司 | 具有抗肿瘤活性的半合成紫杉烷 |
| US6201140B1 (en) * | 1994-07-28 | 2001-03-13 | Bristol-Myers Squibb Company | 7-0-ethers of taxane derivatives |
-
1998
- 1998-02-18 US US09/025,270 patent/US5902822A/en not_active Expired - Fee Related
- 1998-02-24 ES ES98908734T patent/ES2207817T3/es not_active Expired - Lifetime
- 1998-02-24 DE DE69818492T patent/DE69818492T2/de not_active Expired - Fee Related
- 1998-02-24 EP EP98908734A patent/EP1011329B1/de not_active Expired - Lifetime
- 1998-02-24 PT PT98908734T patent/PT1011329E/pt unknown
- 1998-02-24 JP JP53783998A patent/JP2001513778A/ja not_active Ceased
- 1998-02-24 AU AU66686/98A patent/AU724591B2/en not_active Ceased
- 1998-02-24 CA CA002282264A patent/CA2282264A1/en not_active Abandoned
- 1998-02-24 AT AT98908734T patent/ATE250340T1/de not_active IP Right Cessation
- 1998-02-24 DK DK98908734T patent/DK1011329T3/da active
- 1998-02-24 WO PCT/US1998/003741 patent/WO1998037765A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU724591B2 (en) | 2000-09-28 |
| EP1011329A1 (de) | 2000-06-28 |
| US5902822A (en) | 1999-05-11 |
| AU6668698A (en) | 1998-09-18 |
| ES2207817T3 (es) | 2004-06-01 |
| DK1011329T3 (da) | 2003-12-22 |
| DE69818492D1 (en) | 2003-10-30 |
| EP1011329A4 (de) | 2000-07-26 |
| EP1011329B1 (de) | 2003-09-24 |
| CA2282264A1 (en) | 1998-09-03 |
| PT1011329E (pt) | 2004-01-30 |
| WO1998037765A1 (en) | 1998-09-03 |
| DE69818492T2 (de) | 2004-07-22 |
| JP2001513778A (ja) | 2001-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1011329 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |