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ATE2442T1 - Verfahren zur herstellung von interferon und dabei verwendete kulturmediumzusammensetzung. - Google Patents

Verfahren zur herstellung von interferon und dabei verwendete kulturmediumzusammensetzung.

Info

Publication number
ATE2442T1
ATE2442T1 AT80400416T AT80400416T ATE2442T1 AT E2442 T1 ATE2442 T1 AT E2442T1 AT 80400416 T AT80400416 T AT 80400416T AT 80400416 T AT80400416 T AT 80400416T AT E2442 T1 ATE2442 T1 AT E2442T1
Authority
AT
Austria
Prior art keywords
interferon
preparation
culture medium
composition used
medium composition
Prior art date
Application number
AT80400416T
Other languages
English (en)
Inventor
Alfred A. Tytell
Edgar Scattergood
Arthur Kirk Field
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Application granted granted Critical
Publication of ATE2442T1 publication Critical patent/ATE2442T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C12N2500/84—Undefined extracts from animals from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT80400416T 1979-03-30 1980-03-28 Verfahren zur herstellung von interferon und dabei verwendete kulturmediumzusammensetzung. ATE2442T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/025,305 US4198479A (en) 1979-03-30 1979-03-30 Replacement of animal serum proteins by human albumin for growth and interferon production by Namalva cells
EP80400416A EP0017570B1 (de) 1979-03-30 1980-03-28 Verfahren zur Herstellung von Interferon und dabei verwendete Kulturmediumzusammensetzung

Publications (1)

Publication Number Publication Date
ATE2442T1 true ATE2442T1 (de) 1983-03-15

Family

ID=21825245

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80400416T ATE2442T1 (de) 1979-03-30 1980-03-28 Verfahren zur herstellung von interferon und dabei verwendete kulturmediumzusammensetzung.

Country Status (6)

Country Link
US (1) US4198479A (de)
EP (1) EP0017570B1 (de)
JP (1) JPS55131399A (de)
AT (1) ATE2442T1 (de)
DE (1) DE3061854D1 (de)
DK (1) DK133780A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410697B1 (en) * 1979-04-20 2002-06-25 Schering Corporation Process for purifying human leukocyte interferon
US4357422A (en) * 1980-08-14 1982-11-02 Massachusetts Institute Of Technology Method of enhancing interferon production
JPS6045849B2 (ja) * 1980-08-25 1985-10-12 林原 健 ヒトエリトロポエチンの製造方法
JPS5774085A (en) * 1980-10-25 1982-05-10 Ajinomoto Co Inc Culture medium for cells originating from lymphocytes
JPS57194787A (en) * 1981-05-28 1982-11-30 Ajinomoto Co Inc Culture medium for animal cell
US4452893A (en) * 1981-08-03 1984-06-05 Cutter Laboratories, Inc. Cell growth medium supplement
EP0082481B2 (de) * 1981-12-23 1990-09-12 Schering Corporation Stabilisierte alpha-Interferon-Zusammensetzungen und ihre Herstellung
US4758510A (en) * 1981-12-30 1988-07-19 S.V.S. Laboratories, Inc. Simplified in-vitro interferon production
US4490357A (en) * 1981-12-30 1984-12-25 Skurkovich Simon V Simplified in-vitro interferon production
JPS58209993A (ja) * 1982-05-31 1983-12-07 Mochida Pharmaceut Co Ltd インタ−フエロンの産生方法
FR2572093A1 (fr) * 1984-10-22 1986-04-25 Anda Biolog Nouveau milieu de culture cellulaire contenant des cellules de rate humaine, procede de culture utilisant ce milieu de culture, lignees de cellules lymphoblastoides obtenues, application a la production d'interferon, procede de preparation d'interferon et interferon ainsi produit
FR2600076A1 (fr) * 1986-06-12 1987-12-18 Fond Ctre Nal Transfusion Milieu de culture comportant de l'albumine humaine, procede de preparation d'un produit injectable a partir de ce milieu, produit obtenu et son utilisation, composition obtenue
US6231881B1 (en) 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
US6352707B1 (en) 1992-02-24 2002-03-05 Anton-Lewis Usala Transplant encapsulation in a hydrogel matrix to obscure immune recognition
US6207437B1 (en) * 1996-03-11 2001-03-27 Genencor International, Inc. Crystalline protease and method for producing same
AU6349501A (en) * 2000-05-31 2001-12-11 Encelle Inc Method of treating chronic ulcers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3800035A (en) * 1971-12-07 1974-03-26 Smithkline Corp Production of interferon from human leukocytes in the absence of serum
GB1464939A (en) * 1974-01-11 1977-02-16 Anvar Process for the production of interferon
JPS5251009A (en) * 1975-10-17 1977-04-23 Morinaga Milk Ind Co Ltd Method of producing drug for treating marrow leukemia
DE2724918A1 (de) * 1977-06-02 1978-12-14 Thomae Gmbh Dr K Gewinnung und reinigung von humaninterferon
DK485977A (da) * 1977-11-01 1979-05-02 Ess Foodeksport Fremgangsmaade til udvinding af et biologisk aktivt materiale fra svineblodfraktioner
DE2821466A1 (de) * 1978-05-17 1979-11-29 Thomae Gmbh Dr K Verbessertes verfahren zur herstellung von humaninterferon
DE2961658D1 (en) * 1978-05-17 1982-02-18 Thomae Gmbh Dr K Process for preparing human interferon

Also Published As

Publication number Publication date
DK133780A (da) 1980-10-01
JPS55131399A (en) 1980-10-13
EP0017570A1 (de) 1980-10-15
EP0017570B1 (de) 1983-02-09
US4198479A (en) 1980-04-15
DE3061854D1 (en) 1983-03-17

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REZ Deleted due to withdrawal