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ATE125306T1 - Monoklonale antikörper, die einen unterschied zwischen nativproteinen und proteinen mit einer modifizierten sequenz machen. - Google Patents

Monoklonale antikörper, die einen unterschied zwischen nativproteinen und proteinen mit einer modifizierten sequenz machen.

Info

Publication number
ATE125306T1
ATE125306T1 AT91904843T AT91904843T ATE125306T1 AT E125306 T1 ATE125306 T1 AT E125306T1 AT 91904843 T AT91904843 T AT 91904843T AT 91904843 T AT91904843 T AT 91904843T AT E125306 T1 ATE125306 T1 AT E125306T1
Authority
AT
Austria
Prior art keywords
proteins
monoclonal antibodies
modified sequence
difference
make
Prior art date
Application number
AT91904843T
Other languages
English (en)
Inventor
David K Howard
Anne M Gill
Original Assignee
Mallinckrodt Veterinary Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Veterinary Inc filed Critical Mallinckrodt Veterinary Inc
Application granted granted Critical
Publication of ATE125306T1 publication Critical patent/ATE125306T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Testing Of Short-Circuits, Discontinuities, Leakage, Or Incorrect Line Connections (AREA)
  • Testing Relating To Insulation (AREA)
  • Patch Boards (AREA)
  • Gas-Insulated Switchgears (AREA)
  • Cable Accessories (AREA)
AT91904843T 1990-02-02 1991-01-23 Monoklonale antikörper, die einen unterschied zwischen nativproteinen und proteinen mit einer modifizierten sequenz machen. ATE125306T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/474,150 US5266477A (en) 1990-02-02 1990-02-02 Monoclonal antibodies which differentiate between native and modified porcine somatotropins

Publications (1)

Publication Number Publication Date
ATE125306T1 true ATE125306T1 (de) 1995-08-15

Family

ID=23882369

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91904843T ATE125306T1 (de) 1990-02-02 1991-01-23 Monoklonale antikörper, die einen unterschied zwischen nativproteinen und proteinen mit einer modifizierten sequenz machen.

Country Status (11)

Country Link
US (1) US5266477A (de)
EP (1) EP0513227B1 (de)
JP (1) JPH05503429A (de)
AT (1) ATE125306T1 (de)
AU (1) AU660408B2 (de)
BR (1) BR9105983A (de)
CA (1) CA2075038A1 (de)
DE (1) DE69111429T2 (de)
DK (1) DK0513227T3 (de)
ES (1) ES2074707T3 (de)
WO (1) WO1991011529A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6573055B2 (en) 1997-04-21 2003-06-03 Glycozyme, Inc. Determination of recombinant glycosylated proteins and peptides in biological fluids
KR20030074680A (ko) * 2000-12-28 2003-09-19 와이어쓰 스트렙토코커스 뉴모니에 유래 재조합 보호 단백질
EP2438443A4 (de) * 2009-06-02 2012-07-25 Targeted Molecular Diagnostics Llc Verfahren zur erkennung und quantifizierung der p95-komponente von her2/neu (erbb2)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
JPS5630925A (en) * 1979-08-21 1981-03-28 Sumitomo Chem Co Ltd Purification of human growth hormone
US4431739A (en) * 1979-11-05 1984-02-14 Genentech, Inc. Transformant bacterial culture capable of expressing heterologous protein
US4443539A (en) * 1980-02-05 1984-04-17 The Upjohn Company Process for preparing bovine growth hormone
US4487829A (en) * 1982-03-23 1984-12-11 Massachusetts Institute Of Technology Production and use of monoclonal antibodies against adenoviruses
US4623621A (en) * 1982-06-24 1986-11-18 Hoffmann-La Roche Inc. Immunoassay for peptide and protein oligomers
EP0103395A3 (de) * 1982-08-17 1985-05-22 Biogen N.V. DNS-Sequenzen, rekombinante DNS-Moleküle und Verfahren zur Herstellung von rinderwachstumshormonähnlichen Polypeptiden, mit grosser Ausbeute
CA1341012C (en) * 1982-09-27 2000-06-06 Biogen, Inc. Dna sequences, recombinant dna molecules and processes for producing swine growth hormone-like polypeptides
US4864019A (en) * 1985-11-08 1989-09-05 The Salk Institute For Biological Studies Antibodies to inhibin and conjugates produced therefrom
US5089603A (en) * 1989-06-21 1992-02-18 Tanox Biosystems, Inc. Antigenic epitopes present on membrane-bound but not secreted iga
EP0479922A4 (en) * 1989-06-27 1992-06-17 Rush-Presbyterian-St.Luke's Medical Center Monoclonal antibodies to c-reactive protein
ES2058935T3 (es) * 1989-08-04 1994-11-01 Upjohn Co Anticuerpo monoclonal contra restos de lisina acetilados en somatotropina bovina recombinante.

Also Published As

Publication number Publication date
JPH05503429A (ja) 1993-06-10
DE69111429D1 (de) 1995-08-24
ES2074707T3 (es) 1995-09-16
AU7334391A (en) 1991-08-21
AU660408B2 (en) 1995-06-29
WO1991011529A1 (en) 1991-08-08
DK0513227T3 (da) 1995-12-11
US5266477A (en) 1993-11-30
EP0513227B1 (de) 1995-07-19
BR9105983A (pt) 1992-11-17
DE69111429T2 (de) 1996-01-11
CA2075038A1 (en) 1991-08-03
EP0513227A1 (de) 1992-11-19

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