ATE173505T1 - Nukleotidsequenzen kodierend für ein humanes protein mit angiogenetisch-regulatorischen eigenschaften - Google Patents
Nukleotidsequenzen kodierend für ein humanes protein mit angiogenetisch-regulatorischen eigenschaftenInfo
- Publication number
- ATE173505T1 ATE173505T1 AT91916657T AT91916657T ATE173505T1 AT E173505 T1 ATE173505 T1 AT E173505T1 AT 91916657 T AT91916657 T AT 91916657T AT 91916657 T AT91916657 T AT 91916657T AT E173505 T1 ATE173505 T1 AT E173505T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleotide sequences
- angiogenetic
- human protein
- sequences coding
- pct
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 title abstract 2
- 230000001656 angiogenetic effect Effects 0.000 title 1
- 230000001105 regulatory effect Effects 0.000 title 1
- 239000013598 vector Substances 0.000 abstract 2
- 239000002870 angiogenesis inducing agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48315A IT1242149B (it) | 1990-09-27 | 1990-09-27 | Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE173505T1 true ATE173505T1 (de) | 1998-12-15 |
Family
ID=11265849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91916657T ATE173505T1 (de) | 1990-09-27 | 1991-09-26 | Nukleotidsequenzen kodierend für ein humanes protein mit angiogenetisch-regulatorischen eigenschaften |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5919899A (de) |
| EP (1) | EP0550519B1 (de) |
| JP (1) | JP2987203B2 (de) |
| AT (1) | ATE173505T1 (de) |
| AU (1) | AU8635391A (de) |
| CA (1) | CA2092533C (de) |
| DE (1) | DE69130506T2 (de) |
| ES (1) | ES2127730T3 (de) |
| IT (1) | IT1242149B (de) |
| WO (1) | WO1992006194A1 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0506477B1 (de) * | 1991-03-28 | 1999-06-23 | Merck & Co. Inc. | Untereinheit-C des vaskulären endothelialen Zellwachstumsfaktors |
| US7597886B2 (en) | 1994-11-07 | 2009-10-06 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
| US7429646B1 (en) | 1995-06-05 | 2008-09-30 | Human Genome Sciences, Inc. | Antibodies to human tumor necrosis factor receptor-like 2 |
| US7964190B2 (en) | 1996-03-22 | 2011-06-21 | Human Genome Sciences, Inc. | Methods and compositions for decreasing T-cell activity |
| US6635743B1 (en) | 1996-03-22 | 2003-10-21 | Human Genome Sciences, Inc. | Apoptosis inducing molecule II and methods of use |
| EP0954575A2 (de) * | 1996-12-20 | 1999-11-10 | Human Genome Sciences, Inc. | Fuer das zerebellum und embryo spezifisches protein |
| NZ500530A (en) * | 1997-04-25 | 2001-12-21 | Collateral Therapeutics | Truncated VEGF-B, VEGF-C, VEGF-3, PlGF, VRF-2, poxvirus ORF-1 and ORF-2 proteins |
| CA2363779A1 (en) | 1999-02-26 | 2000-08-31 | Human Genome Sciences, Inc. | Human endokine alpha and methods of use |
| US20020164812A1 (en) * | 1999-04-06 | 2002-11-07 | Uab Research Foundation | Method for screening crystallization conditions in solution crystal growth |
| US7727971B2 (en) * | 2000-02-04 | 2010-06-01 | Life Sciences Research Partners Vzw | Use of placental growth factor for treating ischemic muscle disease |
| US7105168B1 (en) * | 2002-06-04 | 2006-09-12 | D. Collen Research Foundation Vzw | Method of improving ischemic muscle function by administering placental growth factor |
| DK2236152T3 (da) | 2000-04-12 | 2014-07-07 | Novozymes Biopharma Dk As | Albuminfusionsproteiner |
| ATE321069T1 (de) * | 2000-05-12 | 2006-04-15 | Vlaams Interuniv Inst Biotech | Verwendung von inhibitoren des plazenta wachstumsfactors für die behandlung einer pathologischen angiogenese, pathologischen arteriogenese, entzündung, tumorbildung und/oder gefässdurchlässigkeit (ödem) |
| WO2003029275A2 (en) * | 2001-10-03 | 2003-04-10 | Regeneron Pharmaceuticals, Inc. | Anti-angiogenic peptides |
| EP1997829A1 (de) | 2001-12-21 | 2008-12-03 | Human Genome Sciences, Inc. | Albumin Fusionsproteine |
| DE60219361T2 (de) * | 2002-02-05 | 2007-12-13 | Geymonat S.P.A. | Verfahren zur rekombinanten herstellung von plazenta wachstumsfaktor |
| ITRM20020119A1 (it) | 2002-03-05 | 2003-09-05 | Geymonat Spa | Composizioni contenenti plgf ad uso farmaceutico e cosmetico. |
| ITRM20020277A1 (it) * | 2002-05-17 | 2003-11-17 | Geymonat Spa | Muteine del fattore di crescita placentare tipo 1, metodo di preparazione e loro applicazioni. |
| AU2003288027A1 (en) | 2002-11-16 | 2004-06-15 | Dade Behring Marburg Gmbh | Scd40l, papp-a and placental growth factor (plgf) used as a biochemical marker combination in cardiovascular diseases |
| WO2005087812A1 (en) * | 2004-03-05 | 2005-09-22 | Ludwig Institute For Cancer Research | Multivalent antibody materials and methods for vegf/pdgf family of growth factors |
| US20060024302A1 (en) * | 2004-03-05 | 2006-02-02 | Ludwig Institute For Cancer Research | Chimeric anti-VEGF-D antibodies and humanized anti-VEGF-D antibodies and methods of using same |
| EA013970B1 (ru) | 2005-03-24 | 2010-08-30 | Тромбоджиникс Н.В. | Антитела к плацентарному фактору роста и способы их применения |
| DE102005022047A1 (de) | 2005-05-09 | 2006-11-30 | Dade Behring Marburg Gmbh | Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung |
| US7867490B2 (en) * | 2005-06-30 | 2011-01-11 | Vib Vzw | Treatment of liver cirrhosis and its complications |
| JP2009501521A (ja) * | 2005-07-13 | 2009-01-22 | ベス イスラエル ディーコネス メディカル センター | 炎症応答を診断および処置する方法 |
| ATE502956T1 (de) * | 2005-08-15 | 2011-04-15 | Vegenics Pty Ltd | Modifizierte vegf und pdgf mit verbesserten angiogenen eigenschaften |
| AU2007254243B2 (en) | 2006-05-17 | 2013-06-13 | Ludwig Institute For Cancer Research | Targeting VEGF-B regulation of fatty acid transporters to modulate human diseases |
| CA2710680C (en) | 2007-12-26 | 2018-10-16 | Vaccinex, Inc. | Anti-c35 antibody combination therapies and methods |
| WO2009089271A1 (en) | 2008-01-07 | 2009-07-16 | Ortho-Clinical Diagnostics, Inc. | Calibrator/control for simultaneous assay of proteins capable of complexing with one another |
| US8741287B2 (en) | 2008-06-18 | 2014-06-03 | Abbott Laboratories | PlGF-1 assay and kits and components thereof |
| US20100004306A1 (en) * | 2008-06-18 | 2010-01-07 | Abbott Laboratories | PIGF-1 Assay and kits and components thereof |
| CA2736929C (en) | 2008-10-02 | 2019-02-26 | Life Sciences Research Partners Vzw | Inhibition of plgf to treat philadelphia chromosome positive leukemia |
| EP2295449A1 (de) | 2009-09-09 | 2011-03-16 | Dompe PHA.R.MA S.p.A. | PLGF-1 in homodimerer Form |
| CN103087153B (zh) * | 2011-10-28 | 2015-05-06 | 上海市第一人民医院 | 一类新的抑制新生血管的小肽及其应用 |
| EP2785739B1 (de) | 2011-12-01 | 2017-03-15 | ThromboGenics N.V. | Verbesserung eines augendrucksenkungsergebnisses |
| WO2014055849A1 (en) | 2012-10-05 | 2014-04-10 | Alere San Diego, Inc. | Methods for diagnosing and prognosing placental dysfunction and pre-eclampsia |
-
1990
- 1990-09-27 IT IT48315A patent/IT1242149B/it active IP Right Grant
-
1991
- 1991-09-26 ES ES91916657T patent/ES2127730T3/es not_active Expired - Lifetime
- 1991-09-26 AU AU86353/91A patent/AU8635391A/en not_active Abandoned
- 1991-09-26 US US08/039,297 patent/US5919899A/en not_active Expired - Lifetime
- 1991-09-26 EP EP91916657A patent/EP0550519B1/de not_active Expired - Lifetime
- 1991-09-26 AT AT91916657T patent/ATE173505T1/de not_active IP Right Cessation
- 1991-09-26 JP JP3515286A patent/JP2987203B2/ja not_active Expired - Lifetime
- 1991-09-26 CA CA002092533A patent/CA2092533C/en not_active Expired - Lifetime
- 1991-09-26 DE DE69130506T patent/DE69130506T2/de not_active Expired - Lifetime
- 1991-09-26 WO PCT/IT1991/000079 patent/WO1992006194A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06503225A (ja) | 1994-04-14 |
| CA2092533A1 (en) | 1992-03-28 |
| JP2987203B2 (ja) | 1999-12-06 |
| EP0550519A1 (de) | 1993-07-14 |
| EP0550519B1 (de) | 1998-11-18 |
| WO1992006194A1 (en) | 1992-04-16 |
| ES2127730T3 (es) | 1999-05-01 |
| US5919899A (en) | 1999-07-06 |
| DE69130506T2 (de) | 1999-06-24 |
| AU8635391A (en) | 1992-04-28 |
| CA2092533C (en) | 2002-05-28 |
| IT9048315A0 (it) | 1990-09-27 |
| IT1242149B (it) | 1994-02-16 |
| DE69130506D1 (de) | 1998-12-24 |
| IT9048315A1 (it) | 1992-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |