|
US7217689B1
(en)
|
1989-10-13 |
2007-05-15 |
Amgen Inc. |
Glycosylation analogs of erythropoietin
|
|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
US5614184A
(en)
|
1992-07-28 |
1997-03-25 |
New England Deaconess Hospital |
Recombinant human erythropoietin mutants and therapeutic methods employing them
|
|
US5989538A
(en)
*
|
1995-02-15 |
1999-11-23 |
Amgen Inc. |
Mpl ligand analogs
|
|
US5696250A
(en)
*
|
1995-02-15 |
1997-12-09 |
Amgen Inc. |
DNA encoding megakaryocyte growth and development factor analogs
|
|
JPH11514232A
(ja)
*
|
1995-10-09 |
1999-12-07 |
ファルマシア・アンド・アップジョン・カンパニー |
N−アセチルガラクトサミニルトランスフェラーゼに対するアクセプターポリペプチド
|
|
KR100400637B1
(ko)
*
|
1996-02-06 |
2004-03-10 |
씨제이 주식회사 |
생물학적으로유용한펩타이드
|
|
JP4301347B2
(ja)
|
1996-03-14 |
2009-07-22 |
ジェネンテク, インコーポレイテッド |
Gdnfおよびgdnf受容体の用途
|
|
US5952226A
(en)
*
|
1996-11-05 |
1999-09-14 |
Modex Therapeutiques |
Hypoxia responsive EPO producing cells
|
|
ATE255634T1
(de)
*
|
1997-09-01 |
2003-12-15 |
Aventis Pharma Gmbh |
Rekombinantes humanes erythropoietin mit vorteilhaftem glykosylierungsmuster
|
|
WO1999029732A2
(en)
|
1997-12-08 |
1999-06-17 |
Lexigen Pharmaceuticals Corporation |
Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation
|
|
ATE339507T1
(de)
|
1998-06-15 |
2006-10-15 |
Gtc Biotherapeutics Inc |
Erythropoietin-analog-menschliches serum-albumin fusionsprotein
|
|
AU774989B2
(en)
*
|
1998-10-23 |
2004-07-15 |
Amgen, Inc. |
Methods and compositions for the prevention and treatment of anemia
|
|
US7304150B1
(en)
|
1998-10-23 |
2007-12-04 |
Amgen Inc. |
Methods and compositions for the prevention and treatment of anemia
|
|
DE19857609A1
(de)
|
1998-12-14 |
2000-06-15 |
Hannelore Ehrenreich |
Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen
|
|
AU781460B2
(en)
*
|
1999-02-12 |
2005-05-26 |
Amgen, Inc. |
Glycosylated leptin compositions and related methods
|
|
US7345019B1
(en)
|
1999-04-13 |
2008-03-18 |
The Kenneth S. Warren Institute, Inc. |
Modulation of excitable tissue function by peripherally administered erythropoietin
|
|
US7309687B1
(en)
|
1999-04-13 |
2007-12-18 |
The Kenneth S. Warren Institute, Inc. |
Methods for treatment and prevention of neuromuscular and muscular conditions by peripherally administered erythropoietin
|
|
US8236561B2
(en)
|
1999-04-15 |
2012-08-07 |
Crucell Holland B.V. |
Efficient production of IgA in recombinant mammalian cells
|
|
US6855544B1
(en)
|
1999-04-15 |
2005-02-15 |
Crucell Holland B.V. |
Recombinant protein production in a human cell
|
|
US7297680B2
(en)
|
1999-04-15 |
2007-11-20 |
Crucell Holland B.V. |
Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
|
|
US7604960B2
(en)
|
1999-04-15 |
2009-10-20 |
Crucell Holland B.V. |
Transient protein expression methods
|
|
AU766507B2
(en)
*
|
1999-05-07 |
2003-10-16 |
Genentech Inc. |
Novel chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
|
|
US6555343B1
(en)
|
1999-05-07 |
2003-04-29 |
Genentech Inc. |
Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
|
|
US6831060B2
(en)
|
1999-05-07 |
2004-12-14 |
Genentech, Inc. |
Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
|
|
CZ299516B6
(cs)
|
1999-07-02 |
2008-08-20 |
F. Hoffmann-La Roche Ag |
Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
|
|
PE20010288A1
(es)
|
1999-07-02 |
2001-03-07 |
Hoffmann La Roche |
Derivados de eritropoyetina
|
|
RU2232163C2
(ru)
*
|
1999-07-02 |
2004-07-10 |
Ф.Хоффманн-Ля Рош Аг |
Конъюгаты эритропоэтина и полиэтиленгликоля, фармацевтические композиции (варианты), способ профилактического и/или терапевтического лечения нарушений и способ получения коньюгата или композиции
|
|
US7067110B1
(en)
|
1999-07-21 |
2006-06-27 |
Emd Lexigen Research Center Corp. |
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
US6617135B1
(en)
|
1999-08-09 |
2003-09-09 |
Emd Lexigen Research Center Corp. |
Multiple cytokine protein complexes
|
|
CA2391080A1
(en)
*
|
1999-11-12 |
2001-05-25 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Erythropoietin forms with improved properties
|
|
US7527961B2
(en)
|
1999-11-26 |
2009-05-05 |
Crucell Holland B.V. |
Production of vaccines
|
|
US7521220B2
(en)
|
1999-11-26 |
2009-04-21 |
Crucell Holland B.V. |
Production of vaccines
|
|
US7192759B1
(en)
|
1999-11-26 |
2007-03-20 |
Crucell Holland B.V. |
Production of vaccines
|
|
WO2001058957A2
(en)
|
2000-02-11 |
2001-08-16 |
Lexigen Pharmaceuticals Corp. |
Enhancing the circulating half-life of antibody-based fusion proteins
|
|
US6586398B1
(en)
*
|
2000-04-07 |
2003-07-01 |
Amgen, Inc. |
Chemically modified novel erythropoietin stimulating protein compositions and methods
|
|
DK2236152T3
(da)
|
2000-04-12 |
2014-07-07 |
Novozymes Biopharma Dk As |
Albuminfusionsproteiner
|
|
ATE395357T1
(de)
*
|
2000-04-21 |
2008-05-15 |
Amgen Inc |
Verfahren und zusammensetzungen zur vermeidung und behandlung von anämie
|
|
SI1311285T1
(de)
|
2000-05-15 |
2005-08-31 |
Hoffmann La Roche |
|
|
US7259146B2
(en)
|
2000-05-26 |
2007-08-21 |
Ortho-Mcneil Pharmaceutical, Inc. |
Neuroprotective peptides
|
|
KR20030064275A
(ko)
|
2000-06-29 |
2003-07-31 |
메르크 파텐트 게엠베하 |
면역싸이토카인 흡수 증강제와의 조합 치료에 의한항체-싸이토카인 융합 단백질 매개 면역 반응 증강
|
|
AU2001276737A1
(en)
|
2000-08-04 |
2002-02-18 |
Chugai Seiyaku Kabushiki Kaisha |
Protein injection preparations
|
|
ES2644275T3
(es)
|
2000-08-11 |
2017-11-28 |
Chugai Seiyaku Kabushiki Kaisha |
Preparaciones estabilizadas que contienen anticuerpos
|
|
KR101229995B1
(ko)
|
2000-12-11 |
2013-02-06 |
씨제이 주식회사 |
생체내 에리스로포이에틴 활성이 증진된 융합단백질
|
|
AU2002222740A1
(en)
*
|
2000-12-11 |
2002-06-24 |
Cheil Jedang Corporation |
Fusion protein having the enhanced in vivo activity of erythropoietin
|
|
KR100645843B1
(ko)
|
2000-12-20 |
2006-11-14 |
에프. 호프만-라 로슈 아게 |
에리트로포이에틴 접합체
|
|
US7767643B2
(en)
|
2000-12-29 |
2010-08-03 |
The Kenneth S. Warren Institute, Inc. |
Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs
|
|
US6531121B2
(en)
|
2000-12-29 |
2003-03-11 |
The Kenneth S. Warren Institute, Inc. |
Protection and enhancement of erythropoietin-responsive cells, tissues and organs
|
|
US20030072737A1
(en)
|
2000-12-29 |
2003-04-17 |
Michael Brines |
Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
|
|
PA8536201A1
(es)
|
2000-12-29 |
2002-08-29 |
Kenneth S Warren Inst Inc |
Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina
|
|
KR100896971B1
(ko)
|
2001-02-02 |
2009-05-14 |
오르토-맥네일 파마슈티칼, 인코퍼레이티드 |
프락토피라노오스 설파메이트 및 에리트로포이에틴을포함하는 신경계 기능장애 치료법
|
|
PT1366067E
(pt)
|
2001-03-07 |
2012-11-29 |
Merck Patent Gmbh |
Tecnologia de expressão para proteínas contendo uma unidade de anticorpo de isotipo híbrido
|
|
EP3088412B1
(de)
|
2001-03-09 |
2021-05-05 |
Chugai Seiyaku Kabushiki Kaisha |
Proteinaufreinigungsverfahren
|
|
DE10112825A1
(de)
|
2001-03-16 |
2002-10-02 |
Fresenius Kabi De Gmbh |
HESylierung von Wirkstoffen in wässriger Lösung
|
|
WO2002079415A2
(en)
|
2001-03-30 |
2002-10-10 |
Lexigen Pharmaceuticals Corp. |
Reducing the immunogenicity of fusion proteins
|
|
FR2823220B1
(fr)
*
|
2001-04-04 |
2003-12-12 |
Genodyssee |
Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)
|
|
EP1382964A4
(de)
|
2001-04-17 |
2009-06-10 |
Chugai Pharmaceutical Co Ltd |
Verfahren zur tensid-quantifizierung
|
|
JP4309662B2
(ja)
|
2001-05-03 |
2009-08-05 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
腫瘍特異的組換え抗体およびその使用
|
|
US6930086B2
(en)
*
|
2001-09-25 |
2005-08-16 |
Hoffmann-La Roche Inc. |
Diglycosylated erythropoietin
|
|
US7214660B2
(en)
*
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
|
US6818613B2
(en)
|
2001-11-07 |
2004-11-16 |
Ortho-Mcneil Pharmaceutical, Inc. |
Aqueous sustained-release formulations of proteins
|
|
BR0214557A
(pt)
|
2001-11-28 |
2006-06-06 |
Ortho Mcneil Pharm Inc |
regime de dosagem de eritropoietina para o tratamento de anemia
|
|
KR100467750B1
(ko)
*
|
2001-11-29 |
2005-01-24 |
씨제이 주식회사 |
생체내 에리스로포이에틴 활성이 증진된 융합단백질
|
|
KR100467751B1
(ko)
*
|
2001-12-03 |
2005-01-24 |
씨제이 주식회사 |
생체내 에리스로포이에틴 활성이 증진된 융합단백질
|
|
CN100390282C
(zh)
|
2001-12-04 |
2008-05-28 |
默克专利有限公司 |
具有调节的选择性的il-2融合蛋白
|
|
ATE384785T1
(de)
|
2001-12-07 |
2008-02-15 |
Crucell Holland Bv |
Herstellung von viren, virusisolaten, und impfstoffen
|
|
EP1997829A1
(de)
|
2001-12-21 |
2008-12-03 |
Human Genome Sciences, Inc. |
Albumin Fusionsproteine
|
|
DE10209821A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung von Proteinen an ein modifiziertes Polysaccharid
|
|
DE10209822A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
|
|
US7129267B2
(en)
|
2002-03-11 |
2006-10-31 |
Janssen Pharmaceutica N.V. |
Methods for SHP1 mediated neuroprotection
|
|
US20030191056A1
(en)
|
2002-04-04 |
2003-10-09 |
Kenneth Walker |
Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
|
|
MXPA05000063A
(es)
*
|
2002-07-01 |
2005-04-08 |
Kenneth S Warren Inst Inc |
Citocinas recombinantes protectoras de tejido y acidos nucleicos que las codifican para la proteccion, restauracion y mejora de celulas, tejidos y organos respondedores.
|
|
WO2004009627A1
(en)
*
|
2002-07-19 |
2004-01-29 |
Cangene Corporation |
Pegylated erythropoietic compounds
|
|
DE10234192B4
(de)
|
2002-07-26 |
2009-11-26 |
Epoplus Gmbh Co.Kg |
Verwendung von Erythropoetin
|
|
AU2003257536A1
(en)
|
2002-08-27 |
2004-03-19 |
Chugai Seiyaku Kabushiki Kaisha |
Method of stabilizing protein solution preparation
|
|
US7459435B2
(en)
|
2002-08-29 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
|
AU2003263552A1
(en)
|
2002-09-09 |
2004-03-29 |
Nautilus Biotech |
Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
|
|
DE20321793U1
(de)
|
2002-09-11 |
2010-06-02 |
Fresenius Kabi Deutschland Gmbh |
Hydroxyalkylstärke-Derivate
|
|
EP1681303B1
(de)
|
2002-09-11 |
2013-09-04 |
Fresenius Kabi Deutschland GmbH |
HASylierte Polypeptide, besonders HASyliertes Erythropoietin
|
|
RU2329274C2
(ru)
|
2002-09-11 |
2008-07-20 |
Фрезениус Каби Дойчланд Гмбх |
Способ получения производных гидроксиалкилкрахмала
|
|
WO2004024752A1
(ja)
|
2002-09-11 |
2004-03-25 |
Chugai Seiyaku Kabushiki Kaisha |
タンパク質精製方法
|
|
EP1549350B1
(de)
|
2002-10-08 |
2008-09-24 |
Fresenius Kabi Deutschland GmbH |
Pharmazeutisch aktive oligosaccharid-conjugate
|
|
AU2003301332B2
(en)
*
|
2002-10-17 |
2008-06-12 |
Pharming Intellectual Property B.V. |
Protein modification
|
|
US7459436B2
(en)
|
2002-11-22 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
|
EP1572748B1
(de)
|
2002-12-17 |
2010-06-23 |
MERCK PATENT GmbH |
Humanisierter antikörper (h14.18) des maus antikörpers 14.18, der gd2 bindet und seine fusion mit il-2
|
|
CA2513213C
(en)
|
2003-01-22 |
2013-07-30 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
EP1615945B1
(de)
|
2003-04-09 |
2011-09-28 |
BioGeneriX AG |
Glycopegylierungsverfahren und durch die verfahren hergestellte proteine/peptide
|
|
NZ542585A
(en)
|
2003-05-09 |
2007-11-30 |
Crucell Holland Bv |
Cultures of PER.C6-immortalized cells and processes for culturing the same to increase product yields therefrom
|
|
US9005625B2
(en)
|
2003-07-25 |
2015-04-14 |
Novo Nordisk A/S |
Antibody toxin conjugates
|
|
KR100632985B1
(ko)
*
|
2003-07-26 |
2006-10-11 |
메덱스젠 주식회사 |
생리활성 조절 단백질의 효능 향상 방법 및 그 예시변이체들
|
|
WO2005014655A2
(en)
|
2003-08-08 |
2005-02-17 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein
|
|
CN1897959A
(zh)
|
2003-09-29 |
2007-01-17 |
沃伦药品公司 |
用于治疗和预防脓毒病和粘连形成的组织保护细胞因子
|
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
|
EP2233150B1
(de)
|
2003-12-30 |
2016-09-07 |
Augustinus Bader |
Erythropoietin zur Anwendung bei der Behandlung von Wunden oder der Transplantation von Zellen
|
|
DK1699821T3
(da)
|
2003-12-31 |
2012-07-16 |
Merck Patent Gmbh |
Fc-ERYTHROPOIETIN-FUSIONSPROTEIN MED FORBEDREDE FARMAKOKINETIKKER
|
|
DE102004004509B4
(de)
|
2004-01-23 |
2010-07-01 |
Epoplus Gmbh Co.Kg |
Einsatz von niedrig dosiertem Erythropoietin zur Stimulation endothelialer Vorläuferzellen sowie zur Organregeneration und Progressionsverlangsamung von Endorganschäden
|
|
CN101659704A
(zh)
|
2004-03-11 |
2010-03-03 |
弗雷泽纽斯卡比德国有限公司 |
通过还原氨基化制备的羟烷基淀粉和蛋白质的偶联物
|
|
WO2006010143A2
(en)
|
2004-07-13 |
2006-01-26 |
Neose Technologies, Inc. |
Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
|
|
US7597884B2
(en)
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
|
JP5948627B2
(ja)
|
2004-10-29 |
2016-07-20 |
レイショファーム ゲーエムベーハー |
線維芽細胞成長因子(fgf)のリモデリングと糖質ペグ化
|
|
US9029331B2
(en)
|
2005-01-10 |
2015-05-12 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
|
US9187546B2
(en)
|
2005-04-08 |
2015-11-17 |
Novo Nordisk A/S |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
|
US9988427B2
(en)
|
2005-05-13 |
2018-06-05 |
Charite Universitaetsmedizen-Berlin |
Erythropoietin variants
|
|
EP1736481A1
(de)
|
2005-05-13 |
2006-12-27 |
Charite Universitätsmedizin-Berlin |
Erythropoietinvarianten
|
|
US20070105755A1
(en)
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
|
CN100432107C
(zh)
*
|
2005-10-25 |
2008-11-12 |
北京大学 |
具有促红细胞生长因子活性的蛋白质及其用途
|
|
WO2007056191A2
(en)
|
2005-11-03 |
2007-05-18 |
Neose Technologies, Inc. |
Nucleotide sugar purification using membranes
|
|
EP4155385A1
(de)
|
2005-12-08 |
2023-03-29 |
Amgen Inc. |
Verbesserte herstellung von glykoproteinen unter verwendung von mangan
|
|
AU2006322028C1
(en)
|
2005-12-08 |
2025-09-04 |
Amgen Inc. |
Improved host cells and culture methods
|
|
DE102006004008A1
(de)
|
2006-01-27 |
2007-08-02 |
Hannelore Prof. Dr. Dr. Ehrenreich |
Verfahren zur Behandlung und/oder Prophylaxe von Multipler Sklerose, sowie Verwendung von Erythropoietin zur Herstellung eines Arzneimittels zur intermittierenden Behandlung und/oder intermittierenden Prophylaxe von Multipler Sklerose
|
|
US8546329B2
(en)
|
2006-03-22 |
2013-10-01 |
Chugai Seiyaku Kabushiki Kaisha |
Erythropoietin solution preparation
|
|
CN101062407A
(zh)
|
2006-04-29 |
2007-10-31 |
中国科学院上海生命科学研究院 |
促红细胞生成素在预防或治疗视网膜损伤中的用途
|
|
MX2008014744A
(es)
|
2006-05-19 |
2009-02-10 |
Glycofi Inc |
Composiciones de eritrocpoyetina.
|
|
JP2009544327A
(ja)
|
2006-07-21 |
2009-12-17 |
ノヴォ ノルディスク アー/エス |
O−結合型グリコシル化配列によるペプチドのグリコシル化
|
|
US20090173876A1
(en)
|
2006-07-21 |
2009-07-09 |
Amgen Inc. |
Method of detecting and/or measuring hepcidin in a sample
|
|
CN101505788B
(zh)
|
2006-08-22 |
2013-06-26 |
中外制药株式会社 |
周围神经病变的预防和/或治疗药
|
|
WO2008057683A2
(en)
|
2006-10-03 |
2008-05-15 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates
|
|
CN101337988B
(zh)
*
|
2006-10-31 |
2013-01-09 |
沈阳三生制药有限责任公司 |
一种新的促红细胞生成素类似物
|
|
WO2008058942A2
(en)
|
2006-11-13 |
2008-05-22 |
Charite - Universitätsmedezin Berlin |
Method of cell culture and method of treatment comprising a vepo protein variant
|
|
EP2120998B1
(de)
|
2006-11-28 |
2013-08-07 |
HanAll Biopharma Co., Ltd. |
Modifizierte erythropoetin-polypeptide und ihre verwendungen zur behandlung
|
|
AR065613A1
(es)
|
2007-03-09 |
2009-06-17 |
Chugai Pharmaceutical Co Ltd |
Agentes de proteccion para organos transplantados
|
|
EA017770B1
(ru)
|
2007-04-03 |
2013-03-29 |
Биодженерикс Аг |
Способы лечения с использованием гликопэгилированного g-csf
|
|
CN101778859B
(zh)
|
2007-06-12 |
2014-03-26 |
诺和诺德公司 |
改良的用于生产核苷酸糖的方法
|
|
EP2167115A2
(de)
*
|
2007-06-15 |
2010-03-31 |
University Of Zurich |
Behandlung von alzheimer-krankheit
|
|
RU2335296C1
(ru)
*
|
2007-06-26 |
2008-10-10 |
Сергей Марович Дудкин |
Фармацевтическая композиция для профилактики и лечения неврологических заболеваний
|
|
CN103073631A
(zh)
*
|
2007-07-02 |
2013-05-01 |
沈阳三生制药有限责任公司 |
一种促红细胞生成素类似物
|
|
CN103113464B
(zh)
*
|
2007-07-02 |
2014-08-20 |
沈阳三生制药有限责任公司 |
天然人促红细胞生成素类似物
|
|
WO2009010107A1
(en)
|
2007-07-19 |
2009-01-22 |
Hannelore Ehrenreich |
Use of epo receptor activation or stimulation for the improvement of the edss score in patients with multiple sclerosis
|
|
WO2009043049A2
(en)
|
2007-09-27 |
2009-04-02 |
Amgen Inc. |
Pharmaceutical formulations
|
|
EP3381445B1
(de)
|
2007-11-15 |
2023-10-25 |
Amgen Inc. |
Wässrige antikörperformulierung mit stabilisierung durch antioxidantien zur parenteralen verabreichung
|
|
EP2070950A1
(de)
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Hydroxyalkylstärkederivate und deren Herstellungsverfahren
|
|
EP2247618B1
(de)
|
2008-01-25 |
2014-06-11 |
Amgen, Inc |
Ferroportin-antikörper und anwendungsverfahren
|
|
EP2247743B1
(de)
|
2008-02-08 |
2016-04-06 |
Ambrx, Inc. |
Modifizierte leptin-polypeptide und deren verwendungen
|
|
US20130189239A1
(en)
|
2008-02-27 |
2013-07-25 |
Novo Nordisk A/S |
Conjugated Factor VIII Molecules
|
|
EP2095829A1
(de)
|
2008-02-27 |
2009-09-02 |
LEK Pharmaceuticals D.D. |
Selenhaltige Modifizierungsmittel und Konjugate
|
|
EP2811017A2
(de)
|
2008-04-21 |
2014-12-10 |
Novo Nordisk Health Care AG |
Hyperglycosylierter humaner Koagulationsfaktor IX
|
|
EP2620448A1
(de)
|
2008-05-01 |
2013-07-31 |
Amgen Inc. |
Anti-hepcidin-antikörper und Verfahren zu ihrer Verwendung
|
|
CN102164954B
(zh)
|
2008-09-23 |
2018-04-06 |
弗·哈夫曼-拉罗切有限公司 |
促红细胞生成素的纯化
|
|
EA019653B1
(ru)
|
2008-09-26 |
2014-05-30 |
Амбркс Инк. |
Модифицированные полипептиды эритропоэтина животных и их применение
|
|
EP3693014A1
(de)
|
2008-11-13 |
2020-08-12 |
The General Hospital Corporation |
Verfahren und zusammensetzungen zur regulierung der eisenhomöostase durch modulierung der bmp6-aktivität
|
|
AU2010216475B2
(en)
*
|
2009-02-19 |
2015-07-09 |
Xellia Pharmaceuticals Aps |
Process for purifying lipopeptides
|
|
US20100272816A1
(en)
|
2009-04-27 |
2010-10-28 |
Wolfgang Rudinger |
Microcapsules comprising liver cells and erythropoietin, methods for preparing said microcapsules and methods for treating a patient comprising applying said microcapsules to the patient
|
|
EP3009447B1
(de)
|
2009-07-24 |
2018-06-06 |
Dr. Reddy's Laboratories, Ltd. |
Herstellung von erythropoesestimulierendem protein unter verwendung von metallionen
|
|
WO2011024025A1
(en)
*
|
2009-08-28 |
2011-03-03 |
Avesthagen Limited |
An erythropoietin analogue and a method thereof
|
|
AU2010310457B2
(en)
|
2009-10-23 |
2015-07-02 |
Amgen Inc. |
Vial adapter and system
|
|
BR112012031121B1
(pt)
|
2010-06-07 |
2022-09-27 |
Amgen Inc |
Dispositivo de distribuição de drogas, kit e método de operar um dispositivo de distribuição de droga utilizável
|
|
US20120115637A1
(en)
|
2010-06-30 |
2012-05-10 |
Nike, Inc. |
Golf Balls Including A Crosslinked Thermoplastic Polyurethane Cover Layer Having Improved Scuff Resistance
|
|
US8193296B2
(en)
|
2010-06-30 |
2012-06-05 |
Nike, Inc. |
Golf balls including crosslinked thermoplastic polyurethane
|
|
RU2451071C1
(ru)
*
|
2010-12-10 |
2012-05-20 |
Российская Федерация, от имени которой выступает Министерство образования и науки Российской Федерации (Минобрнауки России) |
Штамм гибридных культивируемых клеток животных mus musculus - продуцент моноклональных антител к рекомбинантному эритропоэтину человека (варианты)
|
|
AU2012236573B2
(en)
|
2011-03-31 |
2016-06-02 |
Amgen Inc. |
Vial adapter and system
|
|
HUE042822T2
(hu)
|
2011-04-20 |
2019-07-29 |
Amgen Inc |
Automata befecskendezõ szerkezet
|
|
US9089739B2
(en)
|
2011-08-23 |
2015-07-28 |
Nike, Inc. |
Multi-core golf ball having increased initial velocity
|
|
US8979676B2
(en)
|
2011-08-23 |
2015-03-17 |
Nike, Inc. |
Multi-core golf ball having increased initial velocity at high swing speeds relative to low swing speeds
|
|
JP6411213B2
(ja)
|
2011-10-14 |
2018-10-24 |
アムジエン・インコーポレーテツド |
注入器および組立方法
|
|
KR101443257B1
(ko)
*
|
2011-10-18 |
2014-09-19 |
주식회사 종근당 |
낮은 등전점을 갖는 에리스로포이에틴 유사체의 정제방법
|
|
CN102788720B
(zh)
*
|
2012-06-05 |
2016-01-06 |
西北大学 |
一种滤膜辅助分离生物样本中糖蛋白全n-连接糖链及其鉴别方法
|
|
ES2860954T3
(es)
|
2012-11-21 |
2021-10-05 |
Amgen Inc |
Dispositivo de administración de fármacos
|
|
CN103864913A
(zh)
*
|
2012-12-18 |
2014-06-18 |
联亚生技开发股份有限公司 |
重组蛋白
|
|
EP2968760B1
(de)
|
2013-03-15 |
2024-01-03 |
Amgen Inc. |
Medikamentenkassette, autoinjektor und autoinjektorsystem
|
|
BR112015022123B1
(pt)
|
2013-03-15 |
2022-08-09 |
Intrinsic Lifesciences, Llc |
Anticorpos, fragmentos de ligação ao antígeno dos mesmos que se ligam especificamente à hepcidina ou um peptídeo de hepcidina, uso, meio contentor e kit
|
|
BR112015022042B1
(pt)
|
2013-03-15 |
2023-01-10 |
Amgen Inc |
Injetor para injetar um produto terapêutico
|
|
TWI580452B
(zh)
|
2013-03-15 |
2017-05-01 |
安美基公司 |
用於注射器之匣盒、注射器及使用包括自動注射器及匣盒之設備之方法
|
|
EP2976117B1
(de)
|
2013-03-22 |
2020-12-30 |
Amgen Inc. |
Injektor und verfahren zur montage
|
|
WO2015061389A1
(en)
|
2013-10-24 |
2015-04-30 |
Amgen Inc. |
Drug delivery system with temperature-sensitive control
|
|
ES3010716T3
(en)
|
2013-10-24 |
2025-04-04 |
Amgen Inc |
Injector and method of assembly
|
|
KR101414897B1
(ko)
|
2013-11-29 |
2014-07-04 |
씨제이헬스케어 주식회사 |
다베포에틴 알파의 정제 방법
|
|
WO2015119906A1
(en)
|
2014-02-05 |
2015-08-13 |
Amgen Inc. |
Drug delivery system with electromagnetic field generator
|
|
KR102496507B1
(ko)
|
2014-05-07 |
2023-02-03 |
암겐 인코포레이티드 |
충격 감소 요소들을 가진 자동 주사기
|
|
ES3046483T3
(en)
|
2014-06-03 |
2025-12-02 |
Amgen Inc |
Drug delivery system and method of use
|
|
CN107074928B
(zh)
*
|
2014-09-18 |
2021-03-12 |
奥美药业有限公司 |
新型猫促红细胞生成素受体激动剂
|
|
AU2015321462B2
(en)
|
2014-09-22 |
2020-04-30 |
Intrinsic Lifesciences Llc |
Humanized anti-hepcidin antibodies and uses thereof
|
|
US10695506B2
(en)
|
2014-10-14 |
2020-06-30 |
Amgen Inc. |
Drug injection device with visual and audio indicators
|
|
WO2016100055A1
(en)
|
2014-12-19 |
2016-06-23 |
Amgen Inc. |
Drug delivery device with live button or user interface field
|
|
EP3848072A1
(de)
|
2014-12-19 |
2021-07-14 |
Amgen Inc. |
Medikamentenabgabevorrichtung mit näherungssensor
|
|
CA2976935C
(en)
|
2015-02-17 |
2020-03-10 |
Amgen Inc. |
Drug delivery device with vacuum assisted securement and/or feedback
|
|
EP3261690B1
(de)
|
2015-02-27 |
2021-12-15 |
Amgen Inc. |
Arzneimittelabgabevorrichtung mit nadelschutzmechanismus mit abstimmbarem widerstandsschwellwert gegenüber der bewegung des nadelschutzes
|
|
WO2017039786A1
(en)
|
2015-09-02 |
2017-03-09 |
Amgen Inc. |
Syringe assembly adapter for a syringe
|
|
JP7082568B2
(ja)
|
2015-12-09 |
2022-06-08 |
アムジエン・インコーポレーテツド |
信号伝達キャップ付き自動注射器
|
|
WO2017120178A1
(en)
|
2016-01-06 |
2017-07-13 |
Amgen Inc. |
Auto-injector with signaling electronics
|
|
US10604779B2
(en)
|
2016-03-09 |
2020-03-31 |
Jcr Pharmaceuticals Co., Ltd. |
Method for production of mutant-type human erythropoietin
|
|
ES2814287T3
(es)
|
2016-03-15 |
2021-03-26 |
Amgen Inc |
Reducir la probabilidad de rotura de cristal en dispositivos de administración de fármaco
|
|
WO2017189089A1
(en)
|
2016-04-29 |
2017-11-02 |
Amgen Inc. |
Drug delivery device with messaging label
|
|
WO2017192287A1
(en)
|
2016-05-02 |
2017-11-09 |
Amgen Inc. |
Syringe adapter and guide for filling an on-body injector
|
|
MX2018013616A
(es)
|
2016-05-13 |
2019-02-21 |
Amgen Inc |
Montaje de cubierta protectora de vial.
|
|
EP3458988B1
(de)
|
2016-05-16 |
2023-10-18 |
Amgen Inc. |
Datenverschlüsselung in medizinischen vorrichtungen mit eingeschränkter rechenfähigkeit
|
|
GB2550418A
(en)
|
2016-05-20 |
2017-11-22 |
Laing Peter |
An improved vaccine against flaviviruses avoiding elicitation or stimulation of infection-enhancing antibodies
|
|
EP3465124A1
(de)
|
2016-06-03 |
2019-04-10 |
Amgen Inc. |
Wirkungstestvorrichtungen und verfahren für wirkstofffreisetzungsvorrichtungen
|
|
WO2018004842A1
(en)
|
2016-07-01 |
2018-01-04 |
Amgen Inc. |
Drug delivery device having minimized risk of component fracture upon impact events
|
|
WO2018034784A1
(en)
|
2016-08-17 |
2018-02-22 |
Amgen Inc. |
Drug delivery device with placement detection
|
|
US20200261643A1
(en)
|
2016-10-25 |
2020-08-20 |
Amgen Inc. |
On-body injector
|
|
CA3049780A1
(en)
|
2017-01-17 |
2018-07-26 |
Amgen Inc. |
Injection devices and related methods of use and assembly
|
|
WO2018152073A1
(en)
|
2017-02-17 |
2018-08-23 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
|
US11752258B2
(en)
|
2017-02-17 |
2023-09-12 |
Amgen Inc. |
Drug delivery device with sterile fluid flowpath and related method of assembly
|
|
JP6258536B1
(ja)
*
|
2017-03-03 |
2018-01-10 |
協和発酵キリン株式会社 |
ダルベポエチン組成物の製造方法およびダルべポエチン産生細胞の培養方法
|
|
WO2018165143A1
(en)
|
2017-03-06 |
2018-09-13 |
Amgen Inc. |
Drug delivery device with activation prevention feature
|
|
US11571511B2
(en)
|
2017-03-07 |
2023-02-07 |
Amgen Inc. |
Insertion mechanism and method of inserting a needle of a drug delivery device
|
|
US11986624B2
(en)
|
2017-03-09 |
2024-05-21 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
|
CN110446499A
(zh)
|
2017-03-20 |
2019-11-12 |
豪夫迈·罗氏有限公司 |
一种体外糖基工程化红细胞生成刺激蛋白的方法
|
|
SG11201907676PA
(en)
|
2017-03-28 |
2019-09-27 |
Amgen Inc |
Plunger rod and syringe assembly system and method
|
|
US11667686B2
(en)
|
2017-06-06 |
2023-06-06 |
Kindred Biosciences, Inc. |
Erythropoietin and analogs for veterinary use
|
|
MX2019014615A
(es)
|
2017-06-08 |
2020-02-07 |
Amgen Inc |
Dispositivo de administracion de farmacos accionado por par de torsion.
|
|
AU2018280054B2
(en)
|
2017-06-08 |
2023-07-13 |
Amgen Inc. |
Syringe assembly for a drug delivery device and method of assembly
|
|
JP7195276B2
(ja)
|
2017-06-22 |
2022-12-23 |
アムジエン・インコーポレーテツド |
デバイス起動による衝突/衝撃の低減
|
|
MA49461A
(fr)
|
2017-06-23 |
2020-04-29 |
Amgen Inc |
Dispositif électronique d'administration de médicament comprenant un bouchon activé par un ensemble commutateur
|
|
ES2972207T3
(es)
|
2017-07-14 |
2024-06-11 |
Amgen Inc |
Sistema de inserción-retracción de agujas con sistema de resorte de torsión doble
|
|
US11672733B2
(en)
|
2017-07-21 |
2023-06-13 |
Amgen Inc. |
Gas permeable sealing member for drug container and methods of assembly
|
|
EP4085942A1
(de)
|
2017-07-25 |
2022-11-09 |
Amgen Inc. |
Arzneimittelabgabevorrichtung mit getriebemodul und verwandtes verfahren zur montage
|
|
MA49676A
(fr)
|
2017-07-25 |
2020-06-03 |
Amgen Inc |
Dispositif d'administration de médicament doté d'un système d'accès à un récipient et procédé d'assemblage associé
|
|
US12318593B2
(en)
|
2017-08-09 |
2025-06-03 |
Amgen Inc. |
Hydraulic-pneumatic pressurized chamber drug delivery system
|
|
EP3668567A1
(de)
|
2017-08-18 |
2020-06-24 |
Amgen Inc. |
Am körper tragbarer injektor mit sterilem klebepflaster
|
|
US11103636B2
(en)
|
2017-08-22 |
2021-08-31 |
Amgen Inc. |
Needle insertion mechanism for drug delivery device
|
|
ES2939292T3
(es)
|
2017-10-04 |
2023-04-20 |
Amgen Inc |
Adaptador de flujo para dispositivo de administración de fármacos
|
|
WO2019070552A1
(en)
|
2017-10-06 |
2019-04-11 |
Amgen Inc. |
DRUG DELIVERY DEVICE COMPRISING A LOCKOUT ASSEMBLY AND ASSOCIATED ASSEMBLY METHOD
|
|
US11464903B2
(en)
|
2017-10-09 |
2022-10-11 |
Amgen Inc. |
Drug delivery device with drive assembly and related method of assembly
|
|
WO2019090086A1
(en)
|
2017-11-03 |
2019-05-09 |
Amgen Inc. |
Systems and approaches for sterilizing a drug delivery device
|
|
CA3079197A1
(en)
|
2017-11-06 |
2019-05-09 |
Amgen Inc. |
Drug delivery device with placement and flow sensing
|
|
MA50569A
(fr)
|
2017-11-06 |
2020-09-16 |
Amgen Inc |
Ensembles de remplissage-finition et procédés associés
|
|
JP7247174B2
(ja)
|
2017-11-10 |
2023-03-28 |
アムジエン・インコーポレーテツド |
薬物送達デバイスのプランジャ
|
|
EP3710090A1
(de)
|
2017-11-16 |
2020-09-23 |
Amgen Inc. |
Türverriegelungsmechanismus für wirkstofffreisetzungsvorrichtung
|
|
CN111263651B
(zh)
|
2017-11-16 |
2022-06-17 |
安进公司 |
具有停顿和终点检测的自动注射器
|
|
US10835685B2
(en)
|
2018-05-30 |
2020-11-17 |
Amgen Inc. |
Thermal spring release mechanism for a drug delivery device
|
|
US11083840B2
(en)
|
2018-06-01 |
2021-08-10 |
Amgen Inc. |
Modular fluid path assemblies for drug delivery devices
|
|
WO2020023220A1
(en)
|
2018-07-24 |
2020-01-30 |
Amgen Inc. |
Hybrid drug delivery devices with tacky skin attachment portion and related method of preparation
|
|
CN112469454B
(zh)
|
2018-07-24 |
2024-01-26 |
安进公司 |
用于施用药物的输送装置
|
|
EP3826699A1
(de)
|
2018-07-24 |
2021-06-02 |
Amgen Inc. |
Ausgabevorrichtung zur verabreichung von arzneimitteln
|
|
WO2020023336A1
(en)
|
2018-07-24 |
2020-01-30 |
Amgen Inc. |
Hybrid drug delivery devices with grip portion
|
|
CA3103105A1
(en)
|
2018-07-31 |
2020-02-06 |
Amgen Inc. |
Fluid path assembly for a drug delivery device
|
|
EP3856284A1
(de)
|
2018-09-24 |
2021-08-04 |
Amgen Inc. |
Interventionelle dosiersysteme und verfahren
|
|
AR113091A1
(es)
|
2018-09-27 |
2020-01-22 |
Univ Nacional Del Litoral |
Eritropoyetina humana modificada
|
|
US12042642B2
(en)
|
2018-09-28 |
2024-07-23 |
Amgen Inc. |
Muscle wire escapement activation assembly for a drug delivery device
|
|
CA3110529A1
(en)
|
2018-10-02 |
2020-04-09 |
Amgen Inc. |
Injection systems for drug delivery with internal force transmission
|
|
US12151089B2
(en)
|
2018-10-05 |
2024-11-26 |
Amgen Inc. |
Drug delivery device having dose indicator
|
|
AR116703A1
(es)
|
2018-10-15 |
2021-06-02 |
Amgen Inc |
Proceso de ensamblaje de plataforma para un dispositivo de administración de fármacos
|
|
JP7719714B2
(ja)
|
2018-10-15 |
2025-08-06 |
アムジエン・インコーポレーテツド |
ダンピング機構を有する薬物送達装置
|
|
MA54048A
(fr)
|
2018-11-01 |
2022-02-09 |
Amgen Inc |
Dispositifs d'administration de médicament avec rétraction partielle de l'organe d'administration de médicament
|
|
TWI831847B
(zh)
|
2018-11-01 |
2024-02-11 |
美商安進公司 |
部分針頭縮回之藥物遞送裝置及其操作方法
|
|
EP3873563A1
(de)
|
2018-11-01 |
2021-09-08 |
Amgen Inc. |
Vorrichtung zur verabreichung von medikamenten mit partiellem einzug des wirkstoffabgabeelements
|
|
JP7510952B2
(ja)
|
2019-04-24 |
2024-07-04 |
アムジエン・インコーポレーテツド |
シリンジ滅菌確認アセンブリ及び方法
|
|
AU2020337250A1
(en)
|
2019-08-23 |
2022-03-03 |
Amgen Inc. |
Drug delivery device with configurable needle shield engagement components and related methods
|
|
WO2022159414A1
(en)
|
2021-01-22 |
2022-07-28 |
University Of Rochester |
Erythropoietin for gastroinfestinal dysfunction
|
|
CN117320964A
(zh)
|
2021-05-21 |
2023-12-29 |
美国安进公司 |
优化药物容器的灌装方案的方法
|
|
WO2023209074A1
(en)
|
2022-04-28 |
2023-11-02 |
Institut National de la Santé et de la Recherche Médicale |
Methods of restoring erythropoiesis in patients suffering from a sf3b1 mutant myelodysplastic syndrome by correcting coasy mis-splicing
|
|
CN120380163A
(zh)
|
2022-11-02 |
2025-07-25 |
豪夫迈·罗氏有限公司 |
用于生产糖蛋白组合物的方法
|