ATA174885A - METHOD FOR PRODUCING A SOLID DISPERSION OF A PHARMACOLOGICAL ACTIVE SUBSTANCE IN A POLYMERIC MATRICE - Google Patents

METHOD FOR PRODUCING A SOLID DISPERSION OF A PHARMACOLOGICAL ACTIVE SUBSTANCE IN A POLYMERIC MATRICE

Info

Publication number: ATA174885A
Authority: AT; Austria
Prior art keywords: matrice; polymeric; producing; active substance; solid dispersion
Prior art date: 1984-06-14

Application number

AT0174885A

Other languages

German (de)

Other versions

AT391806B (en

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-06-14

Filing date

1985-06-12

Publication date

1990-06-15

1985-06-12 Application filed by Sandoz Ag filed Critical Sandoz Ag

1990-06-15 Publication of ATA174885A publication Critical patent/ATA174885A/en

1990-12-10 Application granted granted Critical

1990-12-10 Publication of AT391806B publication Critical patent/AT391806B/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

AT0174885A 1984-06-14 1985-06-12 METHOD FOR PRODUCING A SOLID DISPERSION OF A PHARMACOLOGICAL ACTIVE SUBSTANCE IN A POLYMERIC MATRIX AT391806B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3422083		1984-06-14
DE3442566		1984-11-22

Publications (2)

Publication Number	Publication Date
ATA174885A true ATA174885A (en)	1990-06-15
AT391806B AT391806B (en)	1990-12-10

Family

ID=25822108

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0174885A AT391806B (en)	1984-06-14	1985-06-12	METHOD FOR PRODUCING A SOLID DISPERSION OF A PHARMACOLOGICAL ACTIVE SUBSTANCE IN A POLYMERIC MATRIX

Country Status (21)

Country	Link
AT (1)	AT391806B (en)
AU (2)	AU587190B2 (en)
BE (1)	BE902626A (en)
CA (1)	CA1264441A (en)
CY (1)	CY1635A (en)
DE (1)	DE3520184C2 (en)
DK (1)	DK167649B1 (en)
ES (1)	ES8702141A1 (en)
FR (1)	FR2565822B1 (en)
GB (3)	GB2160100B (en)
GR (1)	GR851430B (en)
HK (1)	HK25192A (en)
HU (1)	HU198844B (en)
IE (1)	IE58834B1 (en)
IL (1)	IL75490A0 (en)
IT (1)	IT1200080B (en)
LU (1)	LU85946A1 (en)
NL (1)	NL194389C (en)
NZ (1)	NZ212390A (en)
PT (1)	PT80635B (en)
SE (1)	SE504583C2 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1187751B (en) *	1985-10-15	1987-12-23	Eurand Spa	PROCEDURE FOR THE PREPARATION OF SOLID FORMULATIONS OF NIFEDIPINE WITH HIGH BIO AVAILABILITY AND WITH PROLONGED EFFECT AND FORMULATIONS SO OBTAINED
US4816263A (en) *	1987-10-02	1989-03-28	Alza Corporation	Dosage form for treating cardiovascular diseases comprising isradipine
AU3432689A (en) *	1988-03-24	1989-10-16	Bukh Meditec A/S	Controlled release composition
GR1000270B (en) *	1988-09-30	1992-05-12	Alza Corp	Dose for cardiovascular troubles therapy
DK469989D0 (en) *	1989-09-22	1989-09-22	Bukh Meditec	PHARMACEUTICAL PREPARATION
MX9300110A (en) *	1992-01-13	1994-07-29	Gerhard Gergely	PHARMACEUTICAL PREPARATION IN THE FORM OF AN EFFERVESCENCE OR DISINTEGRATION TABLET OR OF AN INSTANT-TYPE GRANULATE AND PROCEDURE FOR ITS PREPARATION.
DE4201179A1 (en) *	1992-01-17	1993-07-22	Alfatec Pharma Gmbh	Granulates or pellets comprising dispersion of active agent in hydrophilic macromolecules - are e.g. for treatment of depression, hypertension, rheumatism, etc.
US5455046A (en) *	1993-09-09	1995-10-03	Edward Mendell Co., Inc.	Sustained release heterodisperse hydrogel systems for insoluble drugs
US6726930B1 (en)	1993-09-09	2004-04-27	Penwest Pharmaceuticals Co.	Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) *	1993-09-09	1998-06-30	Edward Mendell Co., Inc.	Sustained release heterodisperse hydrogel systems--amorphous drugs
GB2281697A (en) *	1993-09-14	1995-03-15	Euro Celtique Sa	Laxative compositions in capsules
EP0859603B1 (en)	1996-07-08	2008-12-17	Penwest Pharmaceuticals Co.	Sustained release matrix for high-dose insoluble drugs
DE19710009A1 (en) *	1997-03-12	1998-09-24	Knoll Ag	Multi-phase preparation forms containing active ingredients
US6056977A (en)	1997-10-15	2000-05-02	Edward Mendell Co., Inc.	Once-a-day controlled release sulfonylurea formulation
US6787157B1 (en)	1998-03-10	2004-09-07	Abbott Laboratories	Multiphase active ingredient-containing formulations
US7001892B1 (en)	1999-06-11	2006-02-21	Purdue Research Foundation	Pharmaceutical materials and methods for their preparation and use
EP1189599A2 (en) *	1999-06-11	2002-03-27	Eli Lilly And Company	Pharmaceutical materials and methods for their preparation and use
PT1205190E (en) *	1999-08-04	2006-09-29	Astellas Pharma Inc	MEDICINAL COMPOSITIONS STABLE FOR ORAL USE USING IRON OXIDES
MXPA01005370A (en)	1999-09-30	2004-05-14	Penwest Pharmaceuticals Co	Sustained release matrix systems for highly soluble drugs.
ES2261643T3 (en) *	2001-02-13	2006-11-16	Astrazeneca Ab	NEW FORMULATION OF MODIFIED LIBERATION.
US7135436B2 (en)	2003-05-05	2006-11-14	J.F. Daley International, Ltd.	Solid algicide, preparation and usage in recirculating water
EP1690528A1 (en)	2005-02-11	2006-08-16	Abbott GmbH & Co. KG	Process for the preparation of dosage forms comprising a solid dispersion of a microcrystalline active agent
EP2101745A4 (en)	2006-12-05	2009-12-30	Landec Corp	DISTRIBUTION OF MEDICINAL PRODUCTS
US8399007B2 (en)	2006-12-05	2013-03-19	Landec Corporation	Method for formulating a controlled-release pharmaceutical formulation
US8114883B2 (en)	2007-12-04	2012-02-14	Landec Corporation	Polymer formulations for delivery of bioactive materials
BRPI0917358A2 (en) *	2008-08-20	2015-11-17	Univ Texas	controlled release pharmaceutical formulation and method.

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1617362A1 (en) *	1967-11-17	1971-03-25	Beiersdorf Ag	Process for the production of medicaments with delayed release of active substances in the form of capsules
DE2400819C2 (en) *	1974-01-09	1982-04-22	Bayer Ag, 5090 Leverkusen	Process for the production of solid preparations of poorly soluble active pharmaceutical ingredients in extremely fine distribution
DE2546577B2 (en) *	1975-10-17	1981-04-02	Sandoz-Patent-GmbH, 7850 Lörrach	Solid substances made from polyvinylpyrrolidone and ergot alkaloids
DE2549740A1 (en) *	1975-11-17	1977-05-18	Sandoz Ag	NEW GALENIC FORMS AND METHODS FOR THEIR PRODUCTION
GB1579818A (en) *	1977-06-07	1980-11-26	Yamanouchi Pharma Co Ltd	Nifedipine-containing solid preparation composition
CH639659A5 (en) *	1978-12-18	1983-11-30	Sandoz Ag	NEW 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE.
DK149855C (en) *	1977-06-20	1987-04-21	Sandoz Ag	METHOD OF ANALOGY FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINE DERIVATIVES
EP0001247A1 (en) *	1977-09-14	1979-04-04	Kanebo, Ltd.	Pharmaceutical preparation containing nifedipine and a method for producing the same.
CH642259A5 (en) *	1978-12-21	1984-04-13	Sandoz Ag	GALENIC PREPARATIONS FOR ORAL APPLICATION OF ERGOTAL CALOIDS.
DE2904310A1 (en) *	1979-02-05	1980-08-07	Boehringer Mannheim Gmbh	MOLDINGS WITH RETARDED ACTIVE SUBSTANCE RELEASE AND METHOD FOR THE PRODUCTION THEREOF
JPS56115726A (en) *	1980-02-20	1981-09-11	Kaken Pharmaceut Co Ltd	Pharmaceutical containing nifedipine
DE3033919A1 (en) *	1980-09-09	1982-04-22	Bayer Ag, 5090 Leverkusen	SOLID PHARMACEUTICAL PREPARATIONS CONTAINING NIFEDIPINE AND METHOD FOR THE PRODUCTION THEREOF
US4442112A (en) *	1981-09-02	1984-04-10	Sandoz Ltd.	Dihydropyridine derivatives useful in treating vascular headaches
DE3270785D1 (en) *	1981-10-29	1986-05-28	Bayer Ag	Process for preparing solid fast-releasing drug formulations of dihydropyridines
CA1208558A (en) *	1982-10-07	1986-07-29	Kazuo Kigasawa	Soft buccal
DE3318649A1 (en) *	1983-05-21	1984-11-22	Bayer Ag, 5090 Leverkusen	TWO-PHASE FORMULATION

1985
- 1985-05-31 HU HU852126A patent/HU198844B/en unknown
- 1985-05-31 NL NL8501578A patent/NL194389C/en not_active IP Right Cessation
- 1985-06-05 DE DE3520184A patent/DE3520184C2/en not_active Expired - Lifetime
- 1985-06-10 FR FR858508850A patent/FR2565822B1/en not_active Expired
- 1985-06-10 BE BE1/011271A patent/BE902626A/en not_active IP Right Cessation
- 1985-06-12 DK DK264785A patent/DK167649B1/en not_active IP Right Cessation
- 1985-06-12 AT AT0174885A patent/AT391806B/en not_active IP Right Cessation
- 1985-06-12 ES ES544075A patent/ES8702141A1/en not_active Expired
- 1985-06-12 GB GB8514855A patent/GB2160100B/en not_active Expired
- 1985-06-12 GR GR851430A patent/GR851430B/el unknown
- 1985-06-12 IL IL75490A patent/IL75490A0/en not_active IP Right Cessation
- 1985-06-12 PT PT80635A patent/PT80635B/en unknown
- 1985-06-12 AU AU43486/85A patent/AU587190B2/en not_active Ceased
- 1985-06-12 IE IE146085A patent/IE58834B1/en not_active IP Right Cessation
- 1985-06-12 NZ NZ212390A patent/NZ212390A/en unknown
- 1985-06-12 CA CA000483768A patent/CA1264441A/en not_active Expired
- 1985-06-13 IT IT8548210A patent/IT1200080B/en active
- 1985-06-13 SE SE8502950A patent/SE504583C2/en not_active IP Right Cessation
- 1985-06-13 LU LU85946A patent/LU85946A1/en unknown
1987
- 1987-11-19 GB GB8727056A patent/GB2196852B/en not_active Expired
- 1987-11-19 GB GB8727055A patent/GB2196851B/en not_active Expired
1989
- 1989-11-09 AU AU44543/89A patent/AU4454389A/en not_active Abandoned
1992
- 1992-04-02 HK HK251/92A patent/HK25192A/en not_active IP Right Cessation
- 1992-11-06 CY CY1635A patent/CY1635A/en unknown

Also Published As

Publication number	Publication date
SE8502950L (en)	1985-12-15
GB8514855D0 (en)	1985-07-17
LU85946A1 (en)	1986-01-24
AT391806B (en)	1990-12-10
IE851460L (en)	1985-12-14
FR2565822B1 (en)	1989-02-17
DE3520184A1 (en)	1985-12-19
GB2160100B (en)	1989-06-01
ES544075A0 (en)	1987-01-01
DK264785D0 (en)	1985-06-12
IL75490A0 (en)	1985-10-31
IE58834B1 (en)	1993-11-17
SE8502950D0 (en)	1985-06-13
NL194389B (en)	2001-11-01
HUT40918A (en)	1987-03-30
IT8548210A0 (en)	1985-06-13
GB2160100A (en)	1985-12-18
CA1264441A (en)	1990-01-16
HU198844B (en)	1989-12-28
GB2196851A (en)	1988-05-11
NL194389C (en)	2002-03-04
NL8501578A (en)	1986-01-02
AU587190B2 (en)	1989-08-10
GR851430B (en)	1985-11-25
DK264785A (en)	1985-12-15
GB2196851B (en)	1989-06-07
HK25192A (en)	1992-04-10
ES8702141A1 (en)	1987-01-01
GB2196852A (en)	1988-05-11
CY1635A (en)	1992-11-06
BE902626A (en)	1985-12-10
NZ212390A (en)	1992-02-25
GB2196852B (en)	1989-05-17
DE3520184C2 (en)	1997-03-13
PT80635B (en)	1987-10-20
FR2565822A1 (en)	1985-12-20
AU4348685A (en)	1985-12-19
SE504583C2 (en)	1997-03-10
IT1200080B (en)	1989-01-05
PT80635A (en)	1985-07-01
GB8727055D0 (en)	1987-12-23
GB8727056D0 (en)	1987-12-23
DK167649B1 (en)	1993-12-06
AU4454389A (en)	1990-03-22

Publication	Publication Date	Title
ATA174885A (en)	1990-06-15	METHOD FOR PRODUCING A SOLID DISPERSION OF A PHARMACOLOGICAL ACTIVE SUBSTANCE IN A POLYMERIC MATRICE
DE69117133D1 (en)	1996-03-28	Method for producing a fuel cell electrode
DE3788821D1 (en)	1994-03-03	Method and device for producing a non-woven fiber film.
DE3855721D1 (en)	1997-02-06	POROUS POLYPROPYLENE MEMBRANE AND METHOD FOR THE PRODUCTION THEREOF
AT386825B (en)	1988-10-25	METHOD FOR PRODUCING NEW BENZIMIDAZOLE DERIVATIVES AND THEIR SALTS
AT389225B (en)	1989-11-10	METHOD FOR PRODUCING NAPROXEN AND NAPROXEN-SODIUM TABLETS WITH CONTROLLED ACTIVE SUBSTANCE RELEASE
DE69128135D1 (en)	1997-12-11	Method for producing a microelectronic device with a first and a second element
AT362347B (en)	1981-05-11	METHOD FOR PRODUCING NEW 3-PHENOXY-3 -PHENYLPROPANAMINES AND THEIR ACID ADDITION SALTS
AT381705B (en)	1986-11-25	METHOD FOR PRODUCING NEW THIAZOLIDINDION DERIVATIVES AND THEIR SALTS
DE68927516D1 (en)	1997-01-16	METHOD FOR PRODUCING AN ELECTRODE WITH DOUBLE POROSITY
DE69301088D1 (en)	1996-02-01	METHOD FOR PRODUCING A MEMBRANE AND ITS USE IN AN ELECTOCHEMICAL CELL
AT381708B (en)	1986-11-25	METHOD FOR PRODUCING NEW MACROLIDES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS
AT373864B (en)	1984-02-27	METHOD FOR PRODUCING AETHYLENE GLYCOL WITH SIMULTANEOUS FORMATION OF AETHYLENE GLYCOL MONOAETHERS AND ALCOHOLS
ATA264183A (en)	1988-12-15	METHOD AND DEVICE FOR MANUFACTURING A FIBER FIBER MATERIAL
ATA92690A (en)	1992-06-15	METHOD FOR PRODUCING A SOLUTION OF CELLULOSE IN N-METHYLMORPHOLIN-N-OXIDE AND WATER
AT368490B (en)	1982-10-11	METHOD FOR PRODUCING NEW ALKYLTHIO-PHENOXY-ALKYLAMINES AND THEIR ACID ADDITION SALTS
DE68923098D1 (en)	1995-07-27	Method of manufacturing a fuel cell.
ATA122788A (en)	1994-05-15	GLASS FILLER MATERIAL AND METHOD FOR PRODUCING A POLYMER MATRIX CONTAINING FILLER MATERIAL
AT381308B (en)	1986-09-25	METHOD FOR PRODUCING NEW FLUOROPROSTACYCLINES AND THEIR SALTS
AT384810B (en)	1988-01-11	METHOD FOR PRODUCING PSORAL-FREE NEW 6-ALKYLANGELICINES AND THEIR SALTS
DE3763380D1 (en)	1990-08-02	METHOD FOR PRODUCING A COMPOSITE STRUCTURE CONSISTING OF AT LEAST ONE PART OF POLYMER MATERIAL AND A PART OF FIBER MATERIAL AND MOLD FOR CARRYING OUT THIS METHOD.
DE69030049D1 (en)	1997-04-10	Method of manufacturing a device with a superconducting film
AT386204B (en)	1988-07-25	METHOD FOR PRODUCING NEW SUBSTITUTED CARBAPENEMES AND THEIR SALTS
ATA36984A (en)	1989-07-15	METHOD FOR PRODUCING NEW SUBSTITUTED 2-PHENYLMETHYLENE-1AMINOALKYLOXIMINOCYCLOALCANES AND THEIR ACID ADDITION SALTS
AT385508B (en)	1988-04-11	METHOD FOR PRODUCING BASIC OXIMETHERS AND THEIR SALTS

Legal Events

Date	Code	Title	Description
2006-02-15	ELA	Expired due to lapse of time